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Abrozin (Promethazine)

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Abrozin belongs to a group of medicines called phenothiazines. Promazine can be used to calm your emotions particularly if you feel restless and agitated, particularly if you are an older person.

Other names for this medication:
Abrozin, Aceegan, Avomine, Basiprom, Biodol, Brumol, Calmkid, Ceedokid, Cofcodyl, Emispan, Enimol, Ethamol, Fevril, Hyperex, Ibuprom, Kidkof, Lagesic, Lincotuss, Metacet, Nimkair, Paracee, Paral, Paramax, Petrox, Phenomet, Pinex, Pizol, Primozyn, Procalm, Progene, Promethazine, Promethegan, Promit, Promyoz, Prosed, Prosip, Prosym, Prozine, Romet, Symol, Synergan, Tixylix, Tymol, Vomin

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Zanaflex, Bactrim, Coreg, Celebrex, Symmetrel

Also known as: Promethazine


{name} (promethazine) belongs to a group of drugs called phenothiazines. It works by changing the actions of chemicals in your brain. Promethazine also acts as an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body.

{name} is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

{name} also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

{name} is not for use in treating symptoms of asthma, pneumonia, or other lower respiratory tract infections.


This section provides information on the proper use of a number of products that contain promethazine. It may not be specific to Abrozin. Please read with care.

Never take rectal suppositories by mouth.

Wash your hands with soap and water before and after using this medicine.

To insert suppository: First remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum. If the suppository is too soft to insert, chill the suppository in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppositories): For allergy symptoms: Adults and teenagers—12.5 milligrams (mg) before meals and at bedtime; or 25 mg at bedtime as needed. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 6.25 to 12.5 mg three times a day; or 25 mg at bedtime as needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For prevention of motion sickness: Adults and teenagers—25 mg twice daily; this initial dose should be taken one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. On other days of travel, 25 mg may be taken on arising and again before the evening meal. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For nausea and vomiting: Adults and teenagers—25 mg for the first dose, then 12.5 to 25 mg every four to six hours if needed. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 0.5 mg per pound of body weight (1.1 mg per kg) or 12.5 to 25 mg every four to six hours as needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For sedation: Adults and teenagers—25 to 50 mg. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg. Children younger than 2 years of age—Use and dose must be determined by your doctor . For control of pain or anxiety before or after surgery: Adults and teenagers—50 mg the night before surgery; 25 to 50 mg after surgery. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 0.5 mg per pound of body weight (1.1 mg per kg) or 12.5 to 25 mg the night before surgery or after the surgery. Children younger than 2 years of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Do not keep outdated medicine or medicine no longer needed.

Keep out of the reach of children.

Detailed Abrozin dosage information

Side effects

The most common side effects associated with Abrozin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Abrozin should not be given to a child younger than 2 years old. Abrozin can cause severe breathing problems or death in very young children. Carefully follow your doctor's instructions when giving this medicine to a child of any age.

You should not take Abrozin if you are allergic to promethazine or to similar medicines such as chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, or trifluperazine.

You should not take Abrozin if you have asthma or another lower respiratory tract disorder.

To make sure Abrozin is safe for you, tell your doctor if you have:

asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder; a sulfite allergy; a history of seizures; a weak immune system (bone marrow depression); glaucoma; enlarged prostate or problems with urination; stomach ulcer or obstruction; heart disease or high blood pressure; liver disease; adrenal gland tumor (pheochromocytoma); low levels of calcium in your blood (hypocalcemia); or if you have ever had a serious side effect while using promethazine or any other phenothiazine.

It is not known whether Abrozin will affect an unborn baby. Animal studies have not shown any effects. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether promethazine passes into breast milk or if it could affect a nursing baby. Tell your doctor if you are nursing prior to using Abrozin.

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Effect of Buddleja officinalis on high-glucose-induced vascular inflammation in human umbilical vein endothelial cells. Analysis of codon usage bias and base compositional constraints in iridovirus genomes. Identification of immunogenic proteins and generation of antibodies against Salmonella Typhimurium using phage display. Moreover, anti-CD52 treatment caused the complete loss of all graft lymphocytes, including plasma cells. We screened a random phage display library to isolate peptides specifically binding to basiliximab. AFM force spectroscopy allowed the mapping of the stiffness distribution at the cross-section of the composite with high spatial resolution. The data also indicated that vitamin C decreased the apparent values of Km and Vmax from T24 cells. The authors report 4 cases in which echocardiographic detection of characteristic right ventricular involvement led to the confirmation of the diagnosis of carcinoid tumour leading to the secondary diagnosis of the primary carcinoid tumour. However, in contrast to observations in is levlen a low dose pill central neurons and PC12 cells where Bcl-2 appears to promote neurite growth, both Bcl-2 and Bcl-xL overexpression dramatically inhibit neurite outgrowth in SGNs. (1982) suggested that such difficulties disclose a high sensitivity to stress, independently of depression and personality.

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Effect of incubation time, inoculum size, temperature, pasteurization time, goat milk powder and whey powder on ACE inhibitory activity in fermented milk by L. The CD34 molecule, which is expressed at various levels on virtually all human hematopoietic progenitor cells (HPC), is a heavy glycosylated molecule with many different epitopes. Histopathological risk factors for survival stratification of surgically treated nodal positive prostate cancer patients are poorly defined as reflected by only one category for nodal metastases. Direct cytotoxicity of TTO on tumour cells in vivo was assessed by transmission electron microscopy. We use specific examples to illustrate the general principle that, in performing laboratory testing for thrombophilia, one must always consider the performance characteristics and limitations of the assay in use. Functionally the compliance, contractility, and agonist sensitivity of the tracheal rings matured during preterm to term development. We used a modification of the alkaline single cell gel electrophoresis (SCG) (Comet) what is the generic of prilosec assay to test the in vivo genotoxicity of four hydrazine derivatives--1,2-dimethylhydrazine (SDMH), 1,1-dimethylhydrazine (UDMH), hydrazine (HZ), and procarbazine (PCZ)--in mouse liver, lung, kidney, brain, and bone marrow, and in the mucosa of stomach, colon, and bladder.

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