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We conclude that the HSV-2 enzyme is functional in vivo and that TdR inhibits viral replication by a mechanism other than depletion of dCTP. A new optical design uses a liquid crystal pixel array (LCPA) to discriminate multiple fluorescence signals on a two-dimensional biosensor array. Due to a great number of infected dogs still existing insufficient number of hygienic slaughterhouses, slaughtering livestock without veterinary control, ignorance, lack of education as well as not enough prophylactic measures conducted, this disease represents an outstanding problem. Boosting with partially purified native antigens after priming with recombinant antigens is expected to extend the applicability of the antisera for detecting other structural and non-structural viral antigens by trapping ELISA. Effect of polyvinyl pyrrolidone derivative compound on production of interleukin-1 by monocytes. New developments in computed tomography (CT), magnetic resonance imaging (MR) and ultrasound have reduced the indications for the invasive digital subtraction angiography (DSA). These inhibitors appear to have one common binding site, blocking the entrance to the active site pocket and thus revealing the mode of inhibition by these, and probably other, anions. Clinical and magnetic resonance tomography follow-up of surgically treated aortic isthmus stenoses in adults. The present study has found a significantly depressed hypothalamic content of immunoassayable corticotropin-releasing factor (CRF) in thiouracil treated young rats. The result is rib shortening, a dysplastic thorax that is not only short but also narrowed, and respiratory failure.
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A fifth program, daily restriction started at 2 wk of age, was also compared. In addition, convergence to the asymptotic distribution appears slow for some of the statistics. Prevalence and pattern of substance use among undergraduates in a Nigerian University. This appears to be the first documented instance of a malignant fibrous histiocytoma occurring intracranially after local x-irradiation. Extracts of tissues infected with the squirrel poxvirus cross-react in gel-diffusion tests with extracts of tissues infected with Californian myxoma virus, but not with a similar preparation infected with a South American strain of myxoma virus. Computed tomography did not disclose the cause of hip pain when utilized in two instances. The Changchun isolate was also distinguishable from the other isolates in isoenzyme patterns of GP1, G6PD, HK, 6PGDH and AK, as well as in isoelectric focusing electrophoresis where the Changchun isolate presented a specific band at 4.1 P1. A radiological survey of the female pelvis in Uganda with addendum on the measurements of specimens of the female bony pelvis. The effect of the surface boundary between free space and a conducting medium on the excitation properties of neurons by magnetic fields are analyzed. Although the results obtained represent only an approximation, they nevertheless provide a rare insight into how an antigen (Der p 1) might bind to its antibody (mAb 2C7) while in complex with an anti-idiotype (mAb 2G10).
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The red cell glutathione levels of 10 healthy volunteers who are accustomed to winter-swimming were measured before and after this short-term whole body exposition to hypothermic environment. Three cases, however, of culture-proved endophthalmitis presented without pain. These findings suggest the existence of a natural mechanism of controlling prostaglandin synthesis, possibly related to corticosteroid action. C-type natriuretic peptide (CNP), in contrast, caused half-maximal relaxation at concentrations of 335 and 146 nM in aortas from either wild-type or null mice, respectively, suggesting that this peptide acted through a receptor other than GC-A. However, attempts to immunize guinea pigs by subcutaneous injection of filtered fluid from infected chambers, or with small doses of formalin-killed, chamber gonococci were not successful. The border-zone pattern of cerebral infarction demonstrated by nuclear scintigraphy. In these and most other mammalian species, aggressive behaviour is sexually dimorphic with males being generally more aggressive than females.
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Chest radiographs of thirteen neonates with group B streptococcal septicemia were evaluated for signs of early diagnosis. Analysis of the pH dependence of KD and KT suggests that electrostatic interactions, probably arising from Glu/Asp and Lys/Arg side chains, play a role in the binding process. Evaluation of the stability of biological specimens used for monitoring of occupational exposure. Early distal tubules were isolated from slices of Frog kidneys and the apical membranes exposed by everting the tubule with the aid of microperfusion pipettes. Analysis of spin diffusion and cross correlation on the net nuclear Overhauser effect in NMR. In the third stage, a fine-scale mapping study on the suggestive region was performed in an independent set of 777 affected sib-pairs from 106 families. The experimental results presented herein illustrate pseudo-phase transitions which occur from a non-convectional to convectional state or in the reverse direction. The FT-IR method used also has a traceable calibration to physical properties of the analyte, and the measured spectra can be saved for later analysis.
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Hydrolysis occurs in the vitreous resulting in high rate of active form. Five patients with strongly positive reactions at 48 h showed slower blood flow at the centre of the reaction than at the periphery (central relative slowing, CRS), possibly indicating central ischaemia short of necrosis: no fibrin deposits were seen in the dermal vessels of these skin test sites. The relationship between physician characteristics and prescribing appropriateness. F1 hybrids differ from normotensive controls in their behavioral activity and in salt appetite. Because the right hemisphere appears to play a special role in modulating arousal and interpreting emotional stimuli, it is possible that right hemisphere damage may interfere with developing the computations needed for emotional experience. Early development of spontaneous glomerular lesion in Syrian hamsters of APA strain. Spermatozoa collected from different regions of the ductus epididymidis showed considerable difference in their motility as well as total count with an increase from anterior to posterior region. A comparative study on the effects of apraclonidine and timolol on the ophthalmic blood flow velocity waveforms. Copper, chromium, manganese, nickel and zinc in kidneys of cattle, pigs and sheep and in chicken livers in The Netherlands. Total protein concentration and cholesterol saturation index were significantly greater in the untreated gallstone patients with crystals than in those without crystals in bile.
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The Memorial Sloan-Kettering biomedical cyclotron facility:radioisotope production and labeled compounds. An RNA processing enzyme has been isolated from Caulobacter crescentus which is specific for double-stranded RNA, has an absolute requirement for monovalent cations, and can be eluted from a poly I:C agarose affinity column in pure form. Computed tomography has a more limited role to determine the spatial orientation of a lesion detected only in the lateral mammographic position. These parameters are studied using an endothelial microscope and an image analysis system. Priority targets for individual hospitals may be determined by assessing each hospital. Furthermore, we found that VAMP8 localizes to apical endosomal membranes in nephric tubule epithelium and in MDCK cells.
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Thus, differences in immune complex size, specificity and ability to interact with immunologic effector systems such as complement or cells, suggest variable pathogenic potential. Clinical evaluation of the effects of dibutyryl cyclic AMP on metabolism and circulation. Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1. The used ways were: angiopneumography, pulmonary perfusional scintigraphy, cardiac catheterisation and radiocardiography. Objectivity of subconscious parafunctions with help of integrated electromyography. Quantification of infravesical obstruction is important in the management of clinical benign prostatic hyperplasia (BPH). Clinical and angiographic examinations in occlusion disease of the great intestinal arteries. The association between the concentration of selenium in serum and the risk of degenerative processes of the cardiovascular apparatus or of neoplastic disease remains still uncertain.
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Factors affecting use of food and commercial agents to thicken liquids for individuals with swallowing disorders. Is there electrical coupling between phrenic motoneurons in cats?. Echocardiographic diagnosis of an anomaly of the tricuspid valve in a male pygmy goat. Blood aliquots were collected from the infected unit immediately after inoculation, at 30 min and 1, 5, 10, and 72 h for ultrastructural evaluation. The patients were prospectively randomized in three groups to receive either eltanolone, thiopental, or etomidate. Alternative designs helpful for such purposes are respectively: (i) factorial designs, (ii) historical controls designs, (iii) group-sequential interim analysis designs, (iv) sequential designs for continuous monitoring, (v) therapeutic equivalence designs, (vi) multiple crossover-periods/multiple parallel-groups design, and (vii) increased precision designs through multivariate adjustment. Percentage of lifetime spent in area of residence at time of death.
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The isolated, superfused half-ventricle of the snail (Helix pomatia) maintains a degree of tonic activity even when not beating, since the membrane is depolarized beyond the tension threshold. Pharmacist administration of controlled substances after an earthquake. Near-ultraviolet irradiation of actively growing yeast cells leads to cell death by two distinct mechanisms. Neither a related nor an unrelated HLA-compatible bone marrow donor could be found. Transient atrioventricular conduction disorder: a potential cause of sudden death in myocarditis due to varicella. Post-mortem stability of membrane-associated sialidase activity in brain. Measurement of the permeability of the two surfaces of a living membrane. On the contrary, monolateral involvement in the absence of other signs, as in this case, raises considerable problems of differential diagnosis. The antisera obtained by the above method are devoid or almost devoid of cross-reactive antibodies. It seems that the major properties of the beta-blockers with proven effects on mortality and sudden cardiac death are beta1-receptor blockade and some degree of lipophilicity.
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Studies on stored dextrosecitrated blood with special reference to the leucocytes. Clinico-pathopsychological and catamnestic investigation was performed in 82 patients with manic-depressive psychosis featuring the mixed affective states. Using competitive reverse transcriptase-PCR on mRNA from gastric biopsies, we could show a clear correlation between the amount of IL-8 transcripts and the activity of H. The dependence of the solubilized decarboxylase on the Triton X-100 to phosphatidylserine ratio and the inhibitory effect of Triton X-100 at its molar ratio to phospholipid higher than 5.6 was observed. A case control study was carried out with two groups of patients: patients with anterior knee pain, and patients with no knee pain as a control. Follow-up evaluation included abdominopelvic CT, chest x-ray, urinalysis, blood biochemistry, venous gasometry and ultrasonography with evaluation of postvoid residual urine.
Changes to biological activity following acetylation of dendrotoxin I from Dendroaspis polylepis (black mamba). Generator-produced positron emitting 62Cu-labeled bifunctional radiopharmaceuticals with metabolizable ester groups were synthesized and evaluated for their bifunctionality: the Cu chelating ability and the biochemical reactivity of the ester groups. A psychological autopsy study of suicide in 84 farmers who died between 1991-1994 is presented and some preliminary findings are discussed. Using in situ hybridization with radiolabelled oligonucleotide probes, we studied the mRNA expression of IL-1beta, IL-4, IL-6, IL-10, IL-12, tumour necrosis factor-alpha (TNF-alpha), TNF-beta, interferon-gamma (IFN-gamma), and transforming growth factor-beta (TGF-beta) in the brain during the lethal course of experimental meningitis in a rat model inoculated intracisternally with Haemophilus influenzae type b (Hib) or Streptococcus pneumoniae and in uninfected control rats inoculated with the same volume of PBS. Human mucoepidermoid carcinoma MEC-1 cells induced differentiation by HMBA. The beta 1 subunit of the fibronectin receptors is also found, but with a diffuse pattern, in the osteoclast membrane. Surface electrocardiograph of twelve cases of isolated left ventricular inferior infarction and 24 cases of biventricular inferior infarction confirmed by two-dimensional echocardiography were analysed. Animal experiments showed a decrease in resistance toward respiratory infections that were caused by simultaneous exposure to MnO2 and pathogenic bacteria. Only two cases of this type of metastasis have been previously reported, and these were in the female breast.