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Aclene (Adapalene)

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Aclene is an expensive drug used to treat mild to moderate acne. This drug is slightly more popular than comparable drugs. It is available in generic and brand versions. Over-the-counter Aclene is now available without a prescription.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Klonopin, Lozol, Ovral, Antivert, Compazine, Revia, Propecia

Also known as: Adapalene


{name} (adapalene) is a topical medicine (a medication that is applied to the surface of the skin) similar to vitamin A. It helps the skin to renew itself.

{name} is used to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation.


Follow the directions for using this medicine provided by your doctor. Use Aclene exactly as directed. Aclene is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Aclene. Aclene should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Aclene. Continue using Aclene until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Aclene promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Aclene and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Aclene dosage information

Side effects

The most common side effects associated with Aclene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Selective regulation of different muscarinic receptors in septum and hippocampus neuronal cultures. Electronmicroscopically, the arrangement of PEI particles was observed as two strata along the basement membrane. Neither offspring group received any drug administrations or experimental treatments. Observations based on two contrasting cases of myringitis bullosa haemorrhagica indicate that tympanosclerosis involving the tympanic membrane may have a significant effect on the clinical course of the disease. Strong specific anti-UU fluorescence was detected in 6 of 8 samples, mainly on the midpieces and post-acrosomal regions of the spermatozoa. In all other cases, irradiation has to encompass the whole small pelvis. The clinical approbation of the method gave similar results of the capacitance blood flow with the literature data and with the rheographic method of determination of the cerebral blood flow. Variceal bleeding in children with extrahepatic portal hypertension is best controlled by an effective decompressive shunt. Effects of excess dietary dl-methionine and/or 1-arginine on rats.

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Characteristics of leg extensor muscle in a world champion masters jumper. NPAF is an octadecapeptide isolated from the bovine brain together with neuropeptide FF (NPFF). All patients were followed up by using fine-needle aspiration biopsy and transplant aspiration cytology. Cortical somatosensory evoked potentials in spinal cord injury patients. After the period of monocular vision, single units in striate cortex were tested for visual responsiveness through each eye.

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Determination of serum free amino acids and ammonia in pregnant women with severe pregnancy induced hypertension. The information gained in this study will be useful in developing novel compounds which bind more avidly to the influenza virus hemagglutinin. The four polypeptides produced by the four pDm plasmids require sequences of 4000 base pairs for their translation, and the total amount of DNA in the 37 cloned Dm segments that were tested is approximately 400,000 base pairs. We also demonstrate that the spindle-positioning defects exhibited by dyn1 kip3 cells are caused, to a large extent, by the actions of kinesin- related Kip2p. These data provide an essential baseline for longitudinal study of symptoms associated with the ovarian decline in the perimenopausal years.

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Acute post-partum hemorrhage secondary to a coagulation disorder was successfully treated by embolization of the uterine arteries. The Km for benzylpenicillin, dicloxacillin, cephaloridin and cephalothin was 6.5410(-5), 3 X 10(-4), 2.1 X 10(-5) and 5.7 X 10(-5) M, respectively. Since the introduction of the Angelchik prosthesis for the repair of hiatal hernias in 1979, there have been no previous formal reports of major problems with this procedure. The alteration in pineal and hypothalamic TRH produced by season, and the effect of illumination on pineal TRH content, support the view that TRH has a neuronal function in vertebrates, possibly as a neurotransmitter. The characterization and regional distribution of neuromedin N-like immunoreactivity in rat brain using a highly sensitive and specific radioimmunoassay. It was established that the partitioning released drug was the most important step of drug release.

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The obtained equilibrium data were correlated using the competitive Langmuir isotherm equation, a bi-Langmuir model, the ideal adsorbed solution theory and the real adsorbed solution theory. Patients with squamous cell cancer in the main sites within the head and neck region with the general exception of early T1 N0 tumours were entered into the study by 11 centres. Rate constants for entry into endothelium for both L-glu and mD-glu were high, indicating a quick equilibrium with the aqueous humor. A kinetic spectrophotometric method utilizing competition between p-benzoquinone and tiron for O2 was employed. In addition, about 1 percent of the dialysis patients will commit suicide. Transcipients of this two-step mating retransferred their tetracycline resistance but not bacteriocinogeny to another recipient strain. High levels of CA-125, the specific tumour marker for epithelial ovarian cancers are also found in inflammatory diseases of the pelvis. Inhibition of mouse thymidylate synthase promoter activity by the wild-type p53 tumor suppressor protein. Separate groups of rats were given either 1 or 2 mg/kg injections of amphetamine 30 min before or after eating a preferred high-fat food. It was shown that the optimal extraction of the poliovirus from meat into the solution was seen to occur with the proportions of meat and the eluating solution of 1:8-1:9.

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Concomitant radiochemotherapy in inoperable non-small cell lung cancer. Under these conditions the latter increase in size by way of crystal growth and agglomeration. When the redox state of the mitochondrial NAD couple was calculated from the glutamate dehydrogenase equilibrium, the free energy change (deltaG) corresponding to the potential difference between the NAD couple and cytochrome c was 115.8 kj/mol in the beating heart and 122.2 kj/mol in the arrested heart. Taking advantage of an ongoing study of obesity, this was a survey of a cohort of severely obese men, with a randomly selected control group. Effect of pathological anatomy on the development of the physician and his vocational calling. In this paper albenza pediatric dosage pinworm we analyse whether the dual-labelling, centrifugal-elutriation method is capable of discriminating between exponential and periodic rate-doubling patterns.

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Effect of biotin deficiency on some properties of Staphylococcus aureus isolates from humans and other animals. The correlation between HCT, Hb and the total free amino acid were studied. Recommendations for the reporting of specimens containing oral cavity and oropharynx neoplasms. The plethysmograph is most effective in predictive situations when it is used in conjunction norvasc medicine company with multiple data source. As in both groups there were no significant differences in other parameters further influencing oxygen supply--such as haemoglobin, haematocrit, pH and mean arterial blood pressure--we do not believe that disturbances of perfusion caused by microembolism are mainly responsible for postoperative hypoxaemia. Here the ability of lung cancer cell lines to synthesize neuromedin B (NMB), a structurally similar mammalian bombesin-like peptide, was investigated.

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Caesarean section of the second twin is the rarely clinical situation, but in motivated situation is accepted and reasonable solution. The monitors are designed to accommodate a wide spectrum of criticality accident scenarios from both liquid and metal supercriticalities. The long-term goal of this study is to assess the feasibility of using fetal pig pancreas fragment (FPPF) transplantation to treat patients with type I diabetes. The maps reveal that relatively modest changes in shear rate and/or vessel lumen can cause shifts from high to low likelihood of vessel patency, opening up possible ways of controlling blockage by manipulation of these variables. ALT-946 is a potent inhibitor of advanced renal glycation end-product accumulation and reproduces the renoprotective effects of aminoguanidine. (a) The constituent beta gamma-subunits in the brain membrane G proteins appeared to be divided into two groups in their elution profiles from a hydrophobic column. In animals, methods of access as well as enabling surgical instruments to allow crossclamp of the aorta and performance of the anastomosis were developed. The molecular weight of the mutant was determined by electrospray mass spectrometry, and the presence of the stable acyl enzyme adducts with cephaloridine and cefotaxime was confirmed by both electrospray and MALDI mass spectrometry. Specific fluorescence was localized only in the retina, and not in any other ocular or nonocular tissues. Pentylenetetrazol kindling changes the ability to induce potentiation phenomena in the hippocampal CA1 region.

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Frequent association with myeloid dysplasia and neoplasia and expression of multiple hematopoietic lineage-associated markers forward the hypothesis that myeloma originates in a hematopoietic stem cell. Prokaryotic and eukaryotic 5 S RNAs: primary sequences and proposed secondary structures. But one limitant parameter has been the sample preparation of DNA molecules. Concerning the classification, this disease should not be included among the phacomatoses for there is no biastema tendency, and should bisoprolol zebeta drug class be included among the more general group of neuro-cutaneous dystrophies or genoneurodermatoses. Posterior iliac osteotomy is a recognised method employed to facilitate and support anterior abdominal wall closure in patients with bladder exstrophy, but it adds considerably to the already lengthy procedure of bladder exstrophy surgery. The myoclonus of a 3rd case was believed to be cortical reflex myoclonus on the basis of the emergence of giant SEP, increased LLR and the onset of spikes in the EEGs preceding myoclonic jerks, as ascertained by jerk-locked averaging analysis with muscular discharge. Determination of cardiac output of the artificial heart from the drive air flow. These components were detected at elevated levels in the media of explants of cartilage from the operated joint, and in the synovial fluids of the operated joints.

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