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Acnovate (Adapalene)

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Acnovate is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. Among topical retinoids used to treat acne vulgaris, Acnovate is considered to be the least effective, but best tolerated.

Other names for this medication:
Aclene, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Clinred, Daple, Difra, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Atarax, Alprostadil, Minipress, Deltasone, Sinequan, Flonase, Singulair, Casodex

Also known as: Adapalene


Acnovate is a third-generation topical retinoid primarily used in the treatment of acne. Acnovate is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Acnovate gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Acnovate works under the skin surface to unclog pores and clear up pimples. Acnovate is also known as Adapalene, Adapen, Adaferin. Generic name of Acnovate is Adapalene.


Follow the directions for using this medicine provided by your doctor. Use Acnovate exactly as directed. Acnovate is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Acnovate. Acnovate should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Acnovate. Continue using Acnovate until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Acnovate promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include skin redness, scaling, or irritation.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Acnovate are:

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There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Insulin receptor: role in the resistance of human obesity to insulin. The results are discussed in relation to the properties of the perceptive elements and the cells activating them (habituation, barriers, filling-in). The small (appropriate) concentrations of the metal-binding agents stimulate and stabilize the enzyme activity. Evidence suggests that more aggressive antiretroviral therapy for the mother, which allows suppression of viral loads to undetectable levels, may be safe and may provide significant additional benefits. In contrast, in a further 12 depressed patients, the PRL responses to thyrotropin-releasing hormone, which acts directly on the pituitary to release PRL, were not reduced. The histochemical and immunohistochemical findings in these two cases were confirmed at the ultrastructural level, with most tumor cells containing many neurosecretory granules. The animals which developed disease and suppressed PHA responses were found to be able to confer this loss of PHA reactivity to normal lymphocytes. Incorporation of L-(U- 14 C)leucine into prothrombin by rat liver microsomes and ribosomes. Mean plasma prolactin levels were increased approximately 2.5-fold relative to untreated, ovulatory control cycles. Extracorporeal shock-wave lithotripsy (ESWL) is a treatment that preserves the gallbladder.

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