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Actocard

Actocard is a beta-blocker used to treat chest pain (angina), heart failure, and high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the action of certain natural chemicals in your body (such as epinephrine) that affect the heart and blood vessels. This lowers heart rate, blood pressure, and strain on the heart.

Other names for this medication:
Actiblok, Actocard, Asoprol, Betaloc, Betaone, Blumeta, Cadmet, Dutoprol, Intramet, Macsart, Mepol, Metapro, Metin, Metocare, Metofin, Metolar, Metolex, Metomac, Metoprolol, Metozest, Metpure, Metscore, Metzok, Nexovas, Powermet, Sitelol, Supermet, Telidin, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Also known as: Metoprolol

Description

Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. A lower blood pressure can reduce the risk of strokes and heart attacks.

Metoprolol is also used to treat severe chest pain (angina) and lowers the risk of repeated heart attacks. It is given to people who have already had a heart attack. In addition, metoprolol is used to treat patients with heart failure.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.

Dosage

Take Actocard tablets orally with water. Take Actocard once or twice a day at the same time. Do not crush or chew it. If you want to achieve most effective results do not stop taking Actocard suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast or slow heart rate, trouble breathing, or fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Actocard dosage information

Side effects

The most common side effects associated with Actocard are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Actocard if you are allergic to Actocard components. Do not take Actocard if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Actocard if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Actocard in case of taking cimetidine (Tagamet), clonidine (Catapres), diphenhydramine (Benadryl), fluoxetine (Prozac, Sarafem), hydroxychloroquine, paroxetine (Paxil), propafenone (Rythmol), quinidine (Quinaglute, Quinidex), ranitidine (Zantac), reserpine (Serpalan, Serpasil, Serpatab), ritonavir (Norvir), terbinafine (Lamisil),and thioridazine (Mellaril), bupropion (Wellbutrin). Be careful with Actocard if you have allergies to medicines, foods, or other substances. Be careful with Actocard if you suffer from or have a history of heart or liver disease; diabetes; severe allergies; or an overactive thyroid gland (hyperthyroidism), slow heart rate, heart failure, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat), had asthma or other lung disease. Use Actocard with great care in case you want to undergo an operation (dental or any other). Avoid alcohol. Avoid machine driving. Do not stop taking Actocard suddenly.

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The medical records of 90 dogs that were admitted for primary ocular problems and reacted positive for E. Low-noise temperature measurements at frequencies in the millihertz range are required in the laser interferometer space antenna (LISA) and LISA PathFinder missions. 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates. The study also suggested that fissurectomy followed by 8 weeks of topical DTC may be as good as fissurectomy with BTA injection in the treatment of CAF. This diagnosis should be suggested when hemeralopia is associated with typical fundus aspect resolving after dark adaptation (so called Mizuo-Nakamura phenomenon). Participants displayed a greater tendency to stutter on word-onsets than stressed syllables within words. The high correlations between dissociative experiences and PTS several years after trauma exposure have important clinical implications that may affect their treatment and trauma recovery. tauschii from northern and central Iran, and two hexaploid wheats. Articular ultrasonography is an innocuous methodology, easily reproducible and directly applied by a rheumatologist. Fluorescence in situ hybridization (FISH) and a panel of probes were used to detect cytogenetic aberrations.

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Screening for mutation variants in exons 5, 7, 12 of phenylalanine hydroxylase gene using denaturing gradient gel-electrophoresis. To assess the interpretation of modern criteria for evaluating surgical margins (SMs), by examining the incidence of positive SMs (PSMs) and subsequent biochemical recurrence in a single-surgeon series of radical prostatectomy (RP) at two institutions, as the criteria for determining PSMs after RP are subject to individual interpretation, and this might explain some of the variability in biochemical recurrence rates with different rates of PSMs. A quarter of participants no longer met diagnostic criteria, had not sought further treatment, and their anxiety had not troubled them since treatment. By interacting with each other, these proteins participate in the assembly of molecular platforms, called inflammasomes, which ultimately lead to the activation of cytokines, to the transcription of inflammatory genes or to the induction of cell apoptosis. These include oxidative stress, hyperthermia, excitotoxicity and various apoptotic pathways. This plasmid is commonly used in cotransfections as a measure of transfection efficiency. Promoting activity independent of weight-management appears promising for further study. Follow up weight and height and number of routinely collected weights. Only culture-confirmed cases from sterile fluids were included in the study.

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Infected hosts progressively decrease egg output during the chronic phase of Schistosoma mansoni infection. We present an extension of the Barry and Hartigan model, which can be used to estimate parameters by maximum likelihood (ML) when the data contain invariant sites and there are violations of the assumptions of stationarity, reversibility, and homogeneity. To determine the effectiveness of changes in factors associated with self-efficacy theory for predicting weight change in obese women of two ethnic groups. Confocal laser scanning microscopy (CLSM) was applied in combination with Raman microscopy (RM) for the characterization of heterotrophic biofilms. We evaluated our graph bigram metric against a word-proximity metric for term association on datasets of full-text literature in these three different protein families. gamma(2)(alpha)) were correlated with the delayed neuronal death after CA. This study evaluated the non-linear association between body mass index as a continuous variable and untreated dental decay. Our purpose was to quantify and compare the metabolic and inflammatory changes after laparoscopic and abdominal hysterectomy. Antigens coated with split products of C3, the result of complement activation, are capable of crosslinking the complement receptor 2 (CR2, CD21) and the antigen receptor on the surface of B cells simultaneously. A cDNA for the gene ZFP182, encoding a C2H2-type zinc finger protein, was cloned from rice by RT-PCR.

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The aim of this study was to determine the effect of NRG1 on several oculomotor schizophrenia endophenotypes. Korea is the only developed country that saw an increase in the number of psychiatric beds with the longest average length of stay of psychiatric patients for the past decades. The Sluder method is still generally used in the majority of hospitals in the Netherlands today. Other studies are needed to clarify the potential advantages of the LMA on breastfeeding. The corresponding endocardial structure is the left lateral ridge. This final rule exempts the new system of records, the Healthcare Integrity and Protection Data Bank (HIPDB), from certain provisions of the Privacy Act (5 U.S.C. To this end, we first identified the specific location of 5-HT(2C)-like receptors using immunohistochemistry. To determine the prevalence of Thyroid dysfunction among Type 2 Diabetes mellitus. Clinical application of these results should confirm this finding through randomized research protocols.

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Analysis of vasculature in the telencephalic pallium of a teleost allows the considerable depth of the sulcus externus, which lies at the lateral extent of the ependymal attachment, to be appreciated. The rectal blood supply comes almost exclusively through the superior rectal vessels. A positive oesophageal margin is an independent poor prognostic factor for long-term survival in stomach cancer. Here, we report the identification of a new class of polymer-forming proteins, termed bactofilins, that are widely conserved among bacteria. To evaluate the efficacy and safety of docetaxel (Taxotere) (DTX) and oxaliplatin (OXA) for treatment of recurrent epithelial ovarian cancer.

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The expression of c-erbB-2 protein in colorectal cancer tissue correlates closely with liver metastasis but not with lymphatic or lung metastases. These results should be interpreted with caution as the quality of the evidence was moderate or very low. We developed the pain identification task (PIT), a sequential priming task wherein participants judge the painfulness of target experiences while trying to avoid the influence of prime experiences. Sensitivities and specificities of the annotations on the 300 images by the automated system and a third retinal specialist were determined. Topiramate has been proven to reduce headache frequency and the accompanying disability. The result of this action is the normalization of cell metabolism and the protection of membrane of excitable cells against negative environmental influences.

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In summary, we identified a slfn-2 promoter for the first time and demonstrated that CpG-DNA and LPS triggers slfn-2 gene expression by activating NF-kappaB and AP-1 pathways in macrophages. Blood purification techniques such as continuous renal replacement therapy and plasmapheresis can remove streptococcal exotoxins as well as inflammatory mediators. DOM did not interfere with this LiCl-mediated taste avoidance but significantly decreased LiCl-mediated disgust reactions (head-shaking and wall climbing). The growth of the facial skeleton continues after puberty, but the amount of growth decreases steadily and after the second decade of life seems to be clinically insignificant. The leukemogenic GMP displayed higher levels of beta-catenin activity than either the nontransformed GMP or the transformed nonGMP, both in culture and in transplanted mouse BM. FGF-2 immunoreactivity was concentrated extracellularly in the basal lamina of both glandular and surface epithelium and was abundant and diffusely distributed within myometrial and vascular cells in both cytoplasm and nucleus.

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Data collected from medical records included the baseline social demographic variables and clinical variables. The membrane orientations of the substituted cysteines were determined by treatment with the thiol-specific reagent N-Biotinoylaminoethyl methanethiosulfonate (biotin-MTSEA), combined with the membrane impermeant thiol-specific reagent sodium (2-sulfonatoethyl) methanethiosulfonate (MTSES). Chronic NSAID use has been implicated in the development of severe and potentially life-threatening gastointestinal complications, though certain strategies are known to decrease the risk of these NSAID-related gastointestinal complications. We used a suprasternal Doppler flow technique to measure maternal cardiac output (CO) and corrected flow time (FTc, a measure of intravascular volume) before and after spinal anesthesia after 3 fluid preload regimens. The authors describe this process of gathering unconscious data as one of attention to narrativity, idiosyncratic semanticity, form, and interactive discursive elements. Relation between length of hospital stay and costs of care for patients with community-acquired pneumonia. Fostriecin-mediated G2-M-phase growth arrest correlates with abnormal centrosome replication, the formation of aberrant mitotic spindles, and the inhibition of serine/threonine protein phosphatase activity. The yield of purified hG-CSF and hGM-CSF was 100 and 50 mg/kg of fresh leaves, respectively. Since this procedure does not have the disadvantages usually attributed to TEP, it can be possibly recommended as a first-line procedure, even for unilateral inguinal hernias. Patients were identified using ICD code for BT tumors, 26 patients met inclusion criteria: histologically proven advanced BTC that received GC as their initial chemotherapy.

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Few studies have evaluated prenatal care considerations after these procedures. The investigations showed that the contamination of traditional foods in indigenous peoples of the North was higher than that made in other regions of Russia. Repetitions within a given genealogical tree provide some information about the degree of consanguinity of a population. What determines how satisfactory a size indicator is as a normalizing parameter for small solute clearances in peritoneal dialysis?. Cell-type-specific expression is mediated principally by a single cis-acting enhancer element, termed the insulin control element (ICE), which is acted upon by both these cellular activities. Relatively small toxicant-induced increases in oxidative status are associated with Fyn kinase activation, leading to secondary activation of the c-Cbl ubiquitin ligase. The ideal assessment of technical skills should be defensible and practical. The purpose of this study was to clarify the electrophysiological characteristics of these ATs and attempt the novel approach for catheter ablation. Relationship between objective and subjective assessment of limb function in normal dogs with an experimentally induced lameness.

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The alterations in the pump-perfused isolated lung experiments exceeded those of the pulsatile perfused heart-lung experiments. Intracytoplasmic sperm injection, conventional and molecular cytogenetic analyses. In addition, a controlled drug release of the incorporated PTO-ODN was achieved from these particles. If frequency specificity is not essential, then wavelets and P(episode) are recommended. Severe inflammation and astrocyte loss with profound demyelination in spinal cord and optic nerves are typical pathological features of neuromyelitis optica (NMO). The authors emphasize the paucity of published scientific data that hampers evidence-based medicine recommendations. Our data indicate that spontaneous brain tumors can arise from different cell types in VM mice and that metastatic cancer can represent a disease of macrophage-like cells similar to those described in several human metastatic cancers. To estimate the prevalence of and identify factors associated with physical activity in leisure, transportation, occupational, and household settings. Recent Advances: Discrete regulation of gasotransmitter molecule formation, movement, and reaction is critical to their biological function. In general, these did not negatively impact patient quality of life.

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There has been confusion in the literature and in genome projects regarding the reaction products, the assignment of individual sequences as either cyanuric acid hydrolases or barbiturases, and spurious connection of this family to another protein family. We describe three common work activities, detailing the main actors involved, the tools used and the challenges faced. We analyzed the data using thematic analysis and created treatment availability maps with Google maps. Although attitudes to premarital sex may be influenced by several factors, the importance of religion to that discourse cannot be underestimated. The prognosis was extremely poor, but some proper therapies lead to the prognosis which was equal to that of prostate cancer in Stage D2 without DIC. This ecologic analysis found a correlation between large-scale CT/GC screening in a high-morbidity population and reductions in hospitalized PID, ectopic pregnancies, and ED-diagnosed CT/GC. Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway. The most widely used preclinical models for the acute leukemias are human tumor xenografts established in immune-deficient mice, and genetically engineered mouse strains. These data suggest that the earlier accelerated GnRH pulse generator frequency and advanced puberty with obesogenic diets might be associated with premature up-regulation of kisspeptin and NKB signaling in the hypothalamus of the female rat.

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In contrast to these latter cells, in which DNA synthesis was decreased by TGFbeta1 independently of the cell cycle phases, exponentially growing RAC responded with a stimulation of DNA synthesis while confluent or quiescent cells were growth inhibited. Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells. However, the mechanisms by which haloperidol causes neurotoxicity are not fully understood. In addition to the synchronized longitudinal and circumferential contractions, typical axial displacement cycles could be identified. Laparoscopic cholecystectomy can be safely performed in a resource-limited setting: the first 49 laparoscopic cholecystectomies in Yemen. Here we briefly recount the early breakthroughs concerning the asymmetric hydrogenation of largely unfunctionalized olefins, from the first reports to the advent of chiral Crabtree-like catalysts. The effect of distractors on the shape of oculomotor and manual trajectories provide evidence of such inhibition. This article describes findings from a qualitative study with beneficiaries about their Medicare managed care experiences. Whilst some evidence of a significant change was found in parts of the systems nonlinear response, the effect was small and probably of little physiological relevance. This paper will review the application and relevant research of nasal endoscopic surgery and discuss its further provigil 200 mg perspectives in China.

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Unfortunately, there is little quantitative information available regarding the differences in optical properties of sound enamel, enamel developmental defects, and caries. Additional research is needed to determine the potential cause of this finding. A longitudinal description of heart rate variability in 28--34-week-old preterm infants. The same is true for genomic imprinting which among vertebrates is unique to mammals and represents a special kind of epigenetic modification that is heritable according to parent of origin. Our results indicate a conserved role for GPHR family receptors in controlling germline development and fertility. Chronic stress in free-living European starlings reduces corticosterone concentrations and reproductive success. We use real time transmission electron microscopy observations of the interaction between threading and misfit dislocations in SiGe heterostructures to investigate interactions quantitatively. Cranial subarachnoid hemorrhage (SAH) related to movement of this type of catheter has not been described.

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In situ-hybridization studies showed that glob1 and glob2 expression in An. Nutrient deficiency in the production of artemisinin, dihydroartemisinic acid, and artemisinic acid in Artemisia annua L. Depression is considered one of the most complex mental disorders in the elderly. It is, however, crucial to obtain high-quality plasma or serum in order to avoid increased data variation and thereby increased group sizes. The livers of Smad3-mutant mice were exposed to local irradiation of 15 gray, from a (60)Co-gamma radiation. This sensitivity is mediated by an overproduction of tumor necrosis factor (TNF) and other inflammatory cytokines. The objectives of the present study were to determine the fall rate of in-hospital fallers at home and to explore the risk factors for falls during the immediate post-hospitalization period. curvata embryos cultured in the presence of RA develop into larvae whose trunks are shortened and superficially resemble those of early metamorphosing postlarvae.

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3D-HPLC fingerprints of Kampo medicine and botanical raw materials. These data and the quenching of fluorescence by addition of calcium ions suggest that the enzyme active site is directly involved in the inactivation process. We found that the fast wave showed apparent refraction, whereas the slow wave did not. Genetic effects of workers occupationally exposed to mercury using three genetic end-points. Circulating fibrocytes contribute to the pathogenesis of collagen antibody-induced arthritis. Chemical corrosion protection of optical components using atomic layer deposition. The standards of dental maturation described by Demirjian and Goldstein (1976) may not be suitable for Kuwaiti children. Ultracentrifuged pellets of substance from seminal vesicle secretions were analysed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and flow cytometry. Is growth influencing diameter and function of laparoscopic TESA hepaticojejunostomy?. Although all drug resistant sublines showed cross-resistance to DOC, VCR, and doxorubicin (DXR), the expression of ATP-binding cassette (ABC) transporter B1 (ABCB1) gene was found to be strongly induced in DOC but not in VCR resistant A549 sublines by quantitative reverse transcription real-time polymerase chain reaction (qRT-PCR).

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Visually induced activity in human frontal motor areas during simple visuomotor performance. In humans, recent data suggest that resistin functions as a proinflammatory cytokine. The interactions between the proteins in the network are likely to be responsible for the unusual surface elasticity of the hydrophobin film. The vaccines are regarded as a major contribution to the retreat of the infectious diseases at the XX th century: they allowed a demographic rise without precedent in the world, even if there is still an important shift between the countries. Recent studies have revealed that caspase family of cystine proteases play an important role in the regulation of several apoptotic processes. Our results highlighted the importance of understanding varietal dynamics, an often overlooked component of agriculture drug interactions with inderal sustainability, in addition to evolutionary forces shaping agro-diversity and genetic diversity distribution within crops. Hexane and ether extracts of chicken feathers differ significantly in attractiveness of Culex spp. ABA-induced H(2)O(2) synthesis was normal in these plants, indicating that MPK3 probably acts in signalling downstream of H(2)O(2). Amino acid substitutions in leucine zipper motif in the F-specific domain of human parainfluenza virus 3 HN protein play important roles in the protein function.

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Impaired G(s)alpha and adenylyl cyclase cause beta-adrenoceptor desensitization in chronically hypoxic rat hearts. In almost all cases, there is mineral continuity from the prisms to the underlying foliated layer, as confirmed by X-ray texture analyses. Such images may provide a useful adjunct to surgical planning and education. All patients registered in the study centres who required care between 1 January and 31 December 2008 were finally studied. This agent might have a role in the treatment of patients who require rapid, predictable, and profound but reversible platelet inhibition.

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Participants proposed antiburnout solutions, including promoting the provision of generalist palliative care, frequent rotations on-and-off service, and organizational support for self-care. Cognitive problems are frequently reported in patients with eosinophilia-myalgia syndrome (EMS). Participants of the dementia training achieved a substantial gain of knowledge. E-cadherin and LDLR were regulated at the cell surface in response to R1881 and bicalutamide. Accordingly, the authors developed a novel Social Interaction Empathy Task to examine empathy for physical and psychological pain from first- and third-person perspectives. Hydroxylamine moiety of developmental toxicants is associated with early cell death: a structure-activity analysis. Ultrasound increased BMP-2 expression via PI3K, Akt, c-Fos/c-Jun, and AP-1 pathways in cultured osteoblasts. The energy levels of the BClx reactions between the anatase and rutile surfaces show that the rutile surface has lower energy levels than those of anatase surface. Existing clinical and experimental evidence generally supports a pathogenic role of autoantibodies for blister formation.

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Fluorescence in situ hybridization (FISH) analysis on interphase nuclei confirmed the heterogeneity and amplification of the fused BCR-ABL gene. This level of resolution is needed to investigate the wall shear stress (WSS) distribution, a factor generally recognized as a related to the atherogenesis. Postembryonic development of centrally generated flight motor patterns in the hawkmoth, Manduca sexta. First-in-man experience of percutaneous aortic valve replacement using self-expanding corevalve prosthesis. The analytical precision obtained, when expressed as the average standard deviation for these compounds, was better than 1.6 what happens if you drink alcohol after taking zithromax per thousand. In humans, there are no significant treatment-related effects at the levels tested. Some non-steroidal anti-inflammatory drugs (NSAIDs) incidentally induce hypoglycemia, which is often seen in diabetic patients receiving sulphonylureas.

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It is shown that the proposed regression models obtain favourable performance when compared with the Bayesian method. The aim of this study was to assess the reliability of a newly developed enzyme immunoassay for Helicobacter pylori-specific antigen detection in stools (HpSA) compared to other standardized diagnostic techniques such as histology (H), rapid urease test (RUT) and 13C-urea breath test (UBT) to diagnose H. Recently, a specific nutritional combination containing fish oil, specific oligosaccharide mixture, high protein content and leucine has been developed aimed to support the immune system of cancer patients in order to reduce the frequency and severity of (infectious) complications. These preliminary results may indicate that whenever it is necessary to provide information to the patient it is advisable to do so before cardiac catheterization. 6-month open-label weight loss trial combining sibutramine (a serotonin and noradrenaline reuptake inhibitor) with a can you take other sinus medicine with zyrtec 600-kcal deficit diet and exercise. Interleukin-16 (IL-16) is a pleiotropic cytokine that functions as a chemoattractant factor, a modulator of T cell activation, and an inhibitor of human immunodeficiency virus (HIV) replication.

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