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Addos (Nifedipine)

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Addos is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

Other names for this medication:
Adipine, Afeditab, Atanaal, Buconif, Calcigard, Cardiosol, Cardipin, Carditas, Cardules, Cisday, Citilat, Coral, Cordaflex, Corinfar, Epilat, Fenamon, Ficard, Ficor, Herlat, Hexadilat, Milfadin, Myogard, Nedipin, Nifangin, Nifatenol, Nifcal, Nifecap, Nifedate, Nifedel, Nifedip, Nifedipine, Nifedipinum, Nifensar, Nifestad, Nifezzard, Nilol, Nipin, Nirena, Sepamit, Tenif, Valni, Vasdalat, Viscard, Xepalat, Zenusin

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Addos. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Addos and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Addos are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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A 13-year-old girl with chronic graft versus host disease (GVHD) developed severe proximal weakness. Changes in the reactivity of the pituitary-adrenal system and influence of the sex glands in selection of silver-black foxes by behavior. Distribution and expression of SNAP-25 immunoreactivity in rat brain, rat PC-12 cells and human SMS-KCNR neuroblastoma cells. Inhibition of lymphocyte blastogenesis by factor(s) in alloxan-diabetic rat plasma. Effects of cyclosporine on insulin secretion and insulin sensitivity in dogs with intrasplenic islet autotransplants. Evaluation of endocrine parameters and semen samples: pregnancies following conservative infertility treatment versus IVF therapy. Opportunities for eye health education in the secondary schools. The control group received a single intraperitoneal injection of saline alone.

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After explaining the idea and purpose of cosmetic products, we report on the course of development these products usually take: marketing briefing, selection of the raw materials, serial experiments and stability tests, and finally, dermatophysiological efficacy tests. Since little DHA is present in rat plasma and adrenal and since only estrogens have any effect on the onset of puberty, it is likely that the adrenal is not directly involved in pubertal development in the female rat. The effect of environment on body site temperatures in full-term neonates. However, the fluorescence intensity of T cells labeled with alpha Leu-13, washed and kept at 4 degrees C for different periods, does not diminish more rapidly than the fluorescence of T cells stained with alpha Leu-4 and treated the same way. Samples of human placental lactogen, obtained either as a standard pooled preparation or prepared from individual placentas, were shown to migrate as a single band on acrylamide gel electrophoresis ultram 50 dosing . Further studies are indicated to determine if nutritional support for cardiac cachexia can reduce the levels of morbidity and mortality during mitral and tricuspid valve surgery. Tumour implantation in ischemic, thermic and mechanical lesions of the colonic mucosa. The phosphorylation of H1 histones which occurs during cell replication is reviewed in detail, and it is concluded that there is no clocklike mechanism which couples the phosphorylation of a particular site or region in H1 histones to a set point in the cell cycle.

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Diurnal rhythm in endoplasmic reticulum of rat liver: electron microscopic study. Using immunofluorescent staining with affinity isolated monospecific autoantibodies it was demonstrated that the immunoreactivity of two nuclear antigens (p30 and p85) and one cytoplasmic antigen (p40) was sensitive to the presence of charged polymers. Temporomandibular joint (TMJ) loading and flexibility and the clinical significance of orthopedic appliance therapy are also discussed. Cholesterol absorption efficiency was significantly lower in the apo E 3/3 patients than in the apo E 4/3 group. The following paper is an analysis of 27 consecutive referrals of children, thirteen boys and fourteen girls, in one health district, for assessment on the grounds of possible giftedness, with a view to early placement in a state-maintained school or nursery school. ABO-incompatible bone marrow transplantation: prevention of hemolysis by alkaline hydration with mannitol diuresis in conjunction with red cell reduced buffy coat bone marrow.

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We have cloned the cDNA of a novel human ABC-half-transporter highly similar to peroxisomal ABC-half-transporters such as the adrenoleukodystrophy protein (ALDP) and the peroxisomal protein 70 (PMP70). We complemented this by receptor mutagenesis, followed by additional cleavage and Edman degradation sequencing to refine our insights into the labeled residues. By analyzing chimeric DFRs of Petunia and Gerbera, we identified a region that determines the substrate specificity of DFR. Potassium-selective microelectrodes used for measuring the extracellular brain potassium during spreading depression and anoxic depolarization in rats. Differentiation of smooth and rough Brucella strains by lectins. Although cognitive loss is considered a core symptom of senile dementia, loss of behavioral disinhibition, loss of functional autonomy and mood problems are considered as more important by clinicians and family and are of great diagnostic value. Autogenous skin graft in the treatment of large incisional lumbar hernias can you drink alcohol while on bystolic and bulges. When classified according to their degree of dysplasia, adenomas in the rectum exhibit a significantly higher ratio of AgNOR to nuclear area as the degree of dysplasia increases in severity.

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Immunohistochemical stainings for CD34 and S-100 protein revealed that the former cells showed positivity only for CD34, while the latter were only positive for S-100 protein. Approximately one third of patients have no history of primary cancer at the time of ocular diagnosis. Cells primed with a low concentration of butyrate that itself did not induce activation of caspase-3 or apoptosis were, nevertheless, rendered highly susceptible to induction of apoptosis by staurosporine (an agent that has recently been shown to act by causing mitochondrial release of cytochrome c). It also shows that combined testing has not significantly increased the number of children referred to ENT. The adenovirus 11 strains from American children were antigenically similar to the prototype adenovirus type 11 strain as measured by cross hemagglutination-inhibition procedures. Two unusual cases of metastatic osteosarcoma detected by Tc-99m MDP bone scintigraphy. Proceedings of the thirty-second annual AOA Research Conference, 1988. Norethisterone acetate as secondary endocrine treatment in advanced breast cancer. Inhibition was obtained with hydrocortisone and with nordihydroguaiaretic acid, but not with indomethacin or with the mastocyte membrane stabilizer, sodium cromoglycate. The role of the sympathetic nervous system and catecholamines in the regulation of energy metabolism.

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The control of patients treated by diuretic sulfonamides can be carried out by a radiocompetitive assay using their binding properties to carbonic anhydrase (CA). The Korean version of the neuropsychiatric inventory: a scoring tool for neuropsychiatric disturbance in dementia patients. Our present results suggest that local chemotherapy of malignancies not only may reduce local tumor load, but also may affect distant metastases by facilitating the development of tumor-specific immunity. The influence of serum concentration on lactate dehydrogenase activity. Reduction of radiation dose in diagnostic radiological procedures. The improvement of the lipid profile was accompanied by a marked improvement of the barrier formation as judged from extensive production of lamellar bodies, their complete extrusion at the stratum granulosum/stratum corneum interface, and the formation of multiple broad lipid lamellar structures in the intercorneocyte space. Sources of replenishment of the sex cells: study of sterlet and other sturgeon species. The continent patient had a stable bladder, whereas the others still suffered from unstable bladder contractions despite increased bladder capacity and leak point pressure.

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Late changes after occlusion of the central retinal artery, examined by electrophysiological methods. The presence of insulin inhibits totally the effects of glucagon. Isopycnic centrifugation studies revealed that PAK and PAK(2PfS pili have the same buoyant density in sucrose (1.221 albenza 200 mg tab ) and CsC1 (1.295). Sodium and potassium changes in blood bank stored human erythrocytes. A serum-free chemically-defined culture medium has been formulated that permits determination of the effects of individual growth and trophic factors.

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Surgery of cataracts and on the vitreous body with the Sparta (USA) apparatus. Advantages and limitations of the electrocardiograph in general practice. Physical and clinical evaluation of new high-strip-density radiographic grids. The cleavage of DNA in albendazole 400 mg tablet uses in tamil the presence of Fe(III) did not appear to have any preferred site(s) or sequence(s) for strand scission. A complete medical examination also resulted in negative findings, with the excetion of congenital bilateral talipes equinovarus.

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