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Adefin (Nifedipine)

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Adefin is used to treat hypertension (high blood pressure) and angina (chest pain). Adefin is in a class of drugs called calcium channel blockers. Adefin relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
Adalate, Addos, Adefin, Adipine, Atenerate, Bresben, Buconif, Calcianta, Calcigard, Cardalin, Cardiosol, Cardipin, Carditas, Cardules, Cordalat, Cordilat, Emaberin, Farmalat, Fenamon, Ficard, Glopir, Menoprizin, Nedipin, Nefelid, Nifecap, Nifecardia, Nifed, Nifedalat, Nifedel, Nifedipress, Nifelat, Nifelong, Nifensar, Nifezzard, Nifin, Nipin, Nycopin, Nyefax, Oxcord, Siopelmin, Tredalat, Xepalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


Adefin should be taken orally with or without food. It is better to take Adefin at the same time every day. Take on an empty stomach. Avoid grapefruit juice during treatment with Adefin. If you want to achieve most effective results do not stop taking Adefin suddenly.


If you overdose Adefin and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

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Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Few new techniques have been developed recently to alter host susceptibility, prevent acquisition of virulent pathogens, or eradicate infectious organisms from their sources, but effective infection control programs in hospitals appear to reduce the incidence of nosocomial pulmonary infection, and implementation of these programs deserves serious consideration in all hospitals. The law in relation to the autonomy and physical integrity of persons is explored in this paper. An association between the presence of this vessel and recurring abnormalities of eye movements with alternating ptosis is assumed. A simple method for the x-ray localization of the upper impacted canine. Mature neurons contain two distinct regulated secretory pathways, characterized electron microscopically by so-called large dense core vesicles and small synaptic vesicles, respectively. Distribution of laminin in tumor pathology, Immunofluorescence study. The optimized assay conditions for the enzymatic determination of creatinine in a HITACHI 7250 autoanalyzer was established.

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viciae strain VF39SM plays a central role in FnrN-dependent microaerobic regulation of genes involved in nitrogen fixation. Synthesis and interconversions of C-methyl-branched 1-(3-amino-3-deoxy- -D-hexopyranosyl)uracils. Phorbol diesters promote beta-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes. These decreases suggest the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors. Long-term follow-up of patients treated with implantable cardioverter defibrillators in a Danish centre. Community psychiatry and the public health nurse: evaluation of a training program. Statement by the national specialist qualification advisory committee. It is concluded that self-care does not presently warrant consideration as a social movement. We report a 52 year old man, who without previous thoracic trauma, cardiac diseases or cardiovascular risk factors presented after mild epigastric discomfort acute pulmonary oedema. The best estimates of the number of dependent heroin users in Australia in 1997-1998 from the three methods of estimation were between 67 000 and 92 000 and the median estimate was 74 000.

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What eventually causes the increased number of myofibroblasts and promotes fibrosis is unclear, nor do we know the relative role of hepatocytes or mesenchymal cells in the process of fibroplasis. Plasma levels in luteinizing hormone (LH) and prolactin were measured after oral administration of clomiphene-citrate (CC) at doses of 6 and 12 mg/kg BW/day for 5 consecutive days to broody turkey hens. The patient, a 47-year-old man, with calf claudication, was examined with Doppler velocimetry and angiography. Forty patients with bleeding oesophageal varices were studied during treatment by endoscopic sclerotherapy to discover what factors determine successful outcome. Quantitative evaluation of scanning electron microscopy-examined ciliary morphological changes in control and noise exposed guinea pig cochleas. Based on HPLC analysis we have derived, products from picomole ranges of the drug sample can be detected. Increased insulin binding to erythrocytes in anorexia nervosa: restoration to normal with refeeding. Investigations, in that context, led to the discovery of so far unknown and unexpected properties of this group of medicaments. Care for the complications of dialysis in patients with diabetes mellitus. In order to study factors influencing osteogenesis after bone and bone marrow transplantation, we have caused guinea pigs to become scorbutic, and looked at the cell morphology at sites of bone formation.

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These results suggest that the growth patterns of hepatoblasts are similar in both periportal and nonperiportal regions. This phase transition temperature dependence has been explained as resulting from the formation of lateral phase separations within the membrane bilayer. Effect of topical phenylephrine on the permeability of the blood-aqueous barrier in man. The influence of drugs upon the anticoagulant activity of heparin. We raise the possibilities of particular receptor-ligand combinations and the possible functions of these interactions in the morphogenesis of the head, face, and brain. Concrete and idiosyncratic thinking in acute schizophrenic patients. Experimental therapy of the pneumo-arthritis syndrome of calves. Overall distribution of vasoactive intestinal polypeptide-containing nerves on the wall of cerebral arteries: an immunohistochemical study using whole-mounts. Methylation of C-4 or C-4 and C-17 changes this relatively selective adrenal inhibitor to compounds with increased ovarian/placental inhibitory activity with decreased adrenal inhibitory activity. Neuro-evolutionary accounts of each of the anxiety disorders have been offered.

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Advances in the molecular genetics of hypogonadotropic hypogonadism. This sympathetic regulation of Ito expression may be greatly significant to the genesis of cardiac complications of several diseases such us diabetes mellitus. Anticardiolipin antibodies could be detected in only three patients. 79:369-377, 1989) reported that although supraspinatus is active during arm elevations against gravity, it is silent during the swing phase of quadrupedal locomotion, and instead acts as a joint stabilizer during support phase. Intestinal calcium absorption measured with 91Y as a reference substance was higher in birds during formation of egg shell than in those with inactive uteri. The effect of EMG biofeedback on postoperative pain following abdominal surgery.

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Acid outputs decreased in the control group by the administration of adrenaline, but in the cysteamine-administered group acid outputs increased dose dependently. Protein kinase A activation has no effect on the basal release of PAI-1 and t-PA by human mesangial cells, and, in contrast to endothelial cells, it inhibits both PMA-stimulated PAI-1 and t-PA releases. These findings strongly suggest that the in vivo immunization with PPS delivered to these spontaneously secreting PPS-specific B cells the signals for proliferation as well as differentiation, both of which were expressed in vitro. PPHN should be recognized as a clinical condition associated with a number of pulmonary and systemic diseases. The long form (Ch2L), composed of 92 amino acids (aa), is preferentially expressed in the salivary glands, while the short form (Ch2S), composed of 90 aa, is preferentially expressed in the skin. Mononuclear and giant cells in GCA display the cytoplasmic accumulation of estrogen receptor (ER) alpha. Taken together, these studies have implicated a role for PPARgamma in peripheral nerve cell biology and suggest that the PPARgamma signaling pathway is involved in the regulation of nb cell growth and differentiation.

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Background information on contraception behavior of patients undergoing abortion as an indication of the psychosocial origin of unwanted pregnancies. In all three patients, a synthetic Gortex graft was used for reconstruction of the venous pathways to the left atrium. There was no increase in heart triglycerides of nonketotic rats taken off insulin treatment, although the rats exhibited several indices of diabetes. A review of basic and clinical evidence for this perception does not support the view that an increase in thrombosis-related events has occurred as a results of non-ionic contrast media use in coronary angiographic procedures. Loss of goblet cells and detachment of the columnar epithelial cells were found in the intestinal mucosa of common carp and coloured carp. The inspiratory gas mixture was sampled just at the outlet port of ventilator. A survey of several normal rat tissues revealed that only the stomach contains this unique isozyme of alcohol dehydrogenase. Escherichia coli and Staphylococcus aureus were the major pathogens. Dimensional changes of skin, tongue and nasal epithelia in histological sections were evaluated by t-test. A strategy of health for all--are we reaching our target to reduce mortality?.

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99mTc-sulfur colloid was not absorbed by the bronchial mucosa and therefore appears to be an almost ideal agent. administered as a booster antigen, the antitoxin titer in the serum showed a rapid, steep elevation. In this study we have determined which Galpha proteins are associated with the pancreatic zymogen granule membrane. A satisfactory functional result was obtained in 82 per cent of patients after TVP compared with 73 per cent following PGV and there was little difference between the groups with regard to the incidence of dumping, heartburn and vomiting. cAMP at low temperature increased the cellular uptake of 3H-estradiol, but the grains were not associated with the nuclei. In 2 of 3 cases the signs of herpetic syringitis were limited to the metaplastic duct epithelium, but in 1 case there were also herpetic alterations without ESS. The cloned DNA fragments of 3.8 and 4.7 kb were found to contain the same repetitive element, which was different from previously characterized repetitive elements.

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The relative sizes of the pools and half-times of exchange were highly dependent on the presence of acidic phospholipids and on cytosolic proteins involved in sterol transfer. Effects of a combination of certain drugs inhibiting nucleic acid synthesis processes on transplanted humors. Studies of the primary structures of CAT variants suggest a marked degree of heterogeneity but conservation of amino acid sequence at and near the putative active site. The MVG measured in early diastole in a group of subjects 18 to 45 years old would appear to be an accurate variable used to discriminate between HCM and hypertrophy in athletes. Such myofibrillary dislocation, designated as fibrillar segregation, suggests how myocardial fibres may loose their ability to contract.

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The value of liquid crystal thermography in the diagnosis of spinal root compression syndromes. Cell-specific and inducible Nramp1 gene expression in mouse macrophages in vitro and in vivo. Importantly, treatment recognizing recipient MHC was effective, whereas a similar regimen recognizing donor MHC was not. In one case the change in resonant frequency and corresponding oscillation amplitude is measured whereas in the second case the usual way of recording amplitude and phase signal at a fixed driving frequency is applied. Instead of mixing reagents at the time of testing, previously prepared, labelled reagents were made in economic quantities and used according to the established procedure.

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Automated clean-up procedure for the gas chromatographic-high-resolution mass spectrometric determination of polychlorinated dibenzo-p-dioxins and dibenzofurans in milk. We studied their epidemiological, clinical, hematological, immunological, electrocardiographic (ECG) and echocardiographic characteristics and their in-hospital outcome. Turbojet engine noise, vibrational frequencies and intensities encountered in engine elavil 25 mg pill test cells. They also significantly increased the content of the saturated branched fatty acid with 15 carbon atoms in this culture and decreased the content of the fatty acid of the same type with 19 carbon atoms. Remission of staphylococcal dermatitis by autogenous bacterin therapy.

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The correlation level fluctuates from high with audiometry to low with caloric tests. Gene transfer experiments using estrogen-responsive cells have shown that the 13 bp perfect palindromic element GGTCACTGTGACC found upstream of the Xenopus laevis vitellogenin gene A2 promoter mediates hormonal stimulation and thus, was called the estrogen-responsive element (ERE). Audio-visual aids like video-tapes, which enable the dentists study by themselves at their leisure hours at home, will be a favourable ways of continuing education for busy dentists. Gene expression of TGF-beta1 and IGF-I was enhanced in idiopathic hypertrophic cardiomyopathy and may be associated with its development. Suppression was absent from autologous AML cells exposed to ultraviolet light, or when untreated autologous AML cells were present in ratios of less than 1:1 to lymphocytes, or when added 24 or more hours after stimulation of remission lymphocytes with allogeneic cells. The growth inhibition of HepG2 cells by pyridoxine was accompanied by a marked inhibition of secretion of plasma proteins, particularly albumin. A lactate-fermenting strain of Selenomonas ruminantium (HD4) and a lactatenonfermenting strain (GA192) were examined with respect to the stereoisomers of lactate formed during glucose fermentation, the stereoisomers of lactate fermented by HD4, and the characteristics of the lactate dehydrogenases of the strains. While these trends have usually paralleled high unemployment and increasing income disparities, Sweden had low unemployment and narrowing income differences.

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Enteroclysis and double contrast barium enema are necessary only in very rare cases. Expression of the transgene occurred after 8 weeks of age, at which time the murine immune and central nervous systems are both fully developed. Different kinetic patterns were found for strains having a different structure of mitochondrial mosaic genes, even when the nuclear background was the same. Every hormone known to be normally secreted by endocrine organs or the placenta has been documented to be secreted ectopically by a wide variety of tumors. Loop transverse colostomies as usually constructed without immediate mucocutaneous anastomosis function poorly even a year later, with diarrheal fluid output approaching 1 liter/day on a regular diet. Myeloid antigen expression in childhood acute lymphoblastic leukemia.

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The sensitizing properties of additives to cooling emulsions are reviewed. Spleen cells from F1 mice immunized with nonresponder parental GAT-Mphi developed secondary responses to these GAT-Mphi, but failed to respond to responder parental GAT-Mphi. Ian Govier suggests that patients will benefit if nurses adopt a systematic approach to assessing spiritual needs. In this study, the role of cytokines and neuropeptides in melanin synthesis, which is one indication of the RPE cell differentiation, was examined using chick RPE cells in prilosec dosage per day vitro IL-1beta, TNF-alpha, substance P, beta-endorphin and methionine-enkephalin stimulated the melanin synthesis of RPE cells in a dose-dependent manner. Dimeric DOTA-alpha-melanocyte-stimulating hormone analogs: synthesis and in vivo characteristics of radiopeptides with high in vitro activity. Immediate digestion of fish muscle following field collections yields DNA suitable for RAPD fingerprinting. Corticotropin-releasing factor (CRF) and restraint-stress both decrease exploratory behavior in rats and mice. Potentiating effect of iododeoxyuridine on MuLV replication in mouse embryo fibroblasts. Plasma retinol, alpha-tocopherol, and total tocopherol were estimated by HPLC.

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The NAD level in the organs, calculated to 1 g of the tissue, changed but little and with the estimates covering the whole of the organ there could be noted its substantial drop in the liver, especially after 11 days of fasting (by as much as 62 per cent), and to a lesser degree--in the heart and pancreas and rise in the brain (by 13 per cent). Our study identified substantial differences during the prenatal period and in birth outcomes among the five Hispanic subgroups. Cultivation of the rodent trypanosomes, Trypanosoma lewisi and T. Transport of ions and macromolecules is highly regulated and an important component of host defense. Such progress in immunoassays for cardiac LC has made the measurement of LC an important laboratory test for the diagnosis of AMI. Renal transplantation--a possible factor in the development of circulatory insufficiency in the lower extremities. The results of this study are consistent with the assumption that glucocorticoids regulate the expression of several extracellular matrix molecules in the marrow stroma and thus permit in vitro hematopoiesis to occur. Rats made hypoxic by confinement in hypoxic cages for 4 weeks developed pulmonary hypertension and right ventricular hypertrophy.

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Biliary tract levels generally run parallel to serum levels but were about 15 times higher than those. There was no difference in the incidence of haemorrhagic complications. Marked reduction in cell number of thymus, and moderate effect on cellularity of spleen and MLN, were observed at 20 mg/kg bw. Primary intracranial germ cell tumor in the right basal ganglia and its vicinity area--a report of the case with germinoma and choriocarcinoma histologically. These proteins are members of a conserved family of proteins recognized by a monoclonal antibody that binds to active sites of RNA polymerase II transcription. Oestrogen treatment consisted of the subcutaneous implantation of Silastic capsules containing oestradiol-17beta 3 weeks before ovariectomy.

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Induced changes in the electron paramagnetic resonance spectra of mammalian catalases. The role of lipid peroxidation and biological antioxidants in the function of the adrenal cortex. In neutral gradients, the majority of whole phi105 DNA sedimented as nicked circles and the remainder as oligomers. Mechanism of carbon monoxide oxidation by the carbon monoxide dehydrogenase/acetyl-CoA synthase from Clostridium thermoaceticum: kinetic characterization of the intermediates. Propofol with fentanyl was able to suppress motor and hemodynamic reactions to various noxious stimuli. The Program of Assertive Community Treatment (PACT) has been investigated in Madison and at other replication sites, and the positive results for clients have led to more widespread dissemination of the PACT model. Use and perceptions of antibiotics for upper respiratory infections among college students. Lengthening of circadian period in hamsters by novelty-induced wheel running.

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We design rapidly folding sequences by assigning the strongest couplings to the contacts present in a target native state in a two-dimensional model of heteropolymers. Characterization of a strain E of Rickettsia prowazekii and its pathogenic properties. It is now becoming clear that asthma is a chronic inflammatory disease, involving many interacting cells. A correlation between sulfide production and mucosal immune responses in UC needs to be undertaken. To investigate the diagnostic accuracy, electrocardiogram and hemodynamic effects and safety of dobutamine stress echocardiography. It can and does occur during radiological examinations such as cystourethrography, loopography, and probably during the barium enema. The formation of the peridermal cells is already striking in this region in the early fetal period. Net sodium diovan medication generic and potassium movements seem to be linked to net water flux. The 14 infections that were studied were as follows: one sternal and five leg incisions, five pneumonias, one bacteremia, one urinary tract infection, and one infected internal defibrillator site.

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In these experiments, in addition to mitochondria, labeling with mitochondrial Hsp70 antibody was also observed on the plasma membrane and in unidentified cytoplasmic vesicles and granules. The cerebral B cluster neurones of Aplysia californica were studied under experimental conditions designed to evoke head movements in a selective fashion: either to approach an appetitive stimulus, or to withdraw from an aversive one. The transfected cells were also used to determine whether experimentally introduced methylation patterns are maintained in extrachromosomal viral DNA. In the 3 cases, pneumoperitoneum diagnosis and laparotomy decision were based on the results of an emergency abdominal CT Scan. Free latissimus dorsi myocutaneous flap for secondary breast reconstruction after partial loss of a TRAM flap. Anticonvulsant and sodium channel blocking activity of higher doses of clenbuterol. A computed tomographic scan of the orbit revealed a left-sided retroorbital soft tissue mass, part of which was resected and found be to a metastasis from follicular carcinoma of thyroid. The pantothenic acid requirements of chicks receiving a purified diet. All 21 probes hybridized to the corresponding homoeologous chromosome arms.

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L1-mediated axon outgrowth occurs via a homophilic binding mechanism. Changes were observed more often in axonic terminals than in the endings of specific pain afferent fibres. It was found that the virus was isolated in 5 (3 males and 2 females) of 10 subjects and of the 5 subjects, the virus was isolated from saliva in 4 and from tears in 1. Displaced fractures of the os calcis involving the subtalar joint frequently cause chronic disability due to subsequent osteoarthritis. The review of epidemiological studies published in this field for the last 15 years indicates that most epidemiological studies were carried out using a panel study design of well documented pollinosis subjects. Mutations that attenuated adult beta-globin transcription resulted concomitantly in a proportional increase in expression of the embryonic epsilon-globin gene. The present study indicates that catecholamines are critically involved in the organization of aggressive behavior in ants. Pharmacokinetics and tissue distribution of a DNA-methyltransferase antisense (MT-AS) oligonucleotide and its catabolites in tumor-bearing nude mice. In the study 18 young and 14 elderly patients were subjected to elective abdominal or thoracic surgery, and the IR-ACTH response was determined. The PPT was measured at 3 different rates of pressure application on 3 occasions, 1 week apart.

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A 46-year-old woman was hospitalized with the complaint of right flank pain. The antimalarial activity of Vernonia amygdalina Del (Compositae). Fortification may prove effective in alleviating nutrient deficiencies, but the carrier vehicle must be acceptable to all age groups. Histologic examination of liver tissues from the IH injection site revealed no apparent normal tissue destruction induced by the VPC. The purpose of this review is to summarize the most significant developments during the past 5 yr which are applicable to the practice of intensivists. Age range, mechanism of injury, and associated injuries are quite variable. An explicit solution to these equations giving true corneal thickness in terms of apparent thickness cannot be established, and an iterative procedure is used to develop a relationship for a number of different pachometer configurations. The results show a linear relation between hemolysis area and logarithm of concentration.

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