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Six of these were pure adenocarcinomas, while the remainder consisted of 2 adenocarcinoma with transitional malignant elements, 2 adenosquamous carcinomas and 2 mesonephric adenocarcinomas. A total of 864 persons in highly endemic areas for schistosomiasis were administered either artesunate at a dose of 6 mg/kg once a week for 8 weeks or identical placebo with the same dose-schedule during transmission season for S. Favourable outcome in 33 triplet pregnancies managed between 1985-1990. We studied the cardiac function of 6-week diabetic rats using the isolated perfused heart preparation. Facilitated-diffusion glucose transporter GLUT1 is abundant in the placental barrier, as is the case in other blood-tissue barriers, where GLUT1 is present at the critical plasma membranes of the barrier cells. This pathway could be either an agonist, antagonist or substitutive modulation of the natural retinoid action or a separate pathway.
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One kilogram of a pesticide is not necessarily equal to a kilogram of a different pesticide. Consequently they acquire an early, excessive reliance on anaerobic metabolism and have depression of the ventilatory anaerobic threshold (VAT) and of the slope of the oxygen consumption-work rate relationship (delta VO2/delta WR). Treatment of infections due to Herpesvirus in humans: a critical review of the state of the art. Earlier this method had been used only for reconstruction of high radiation doses obtained accidentally. Picornaviruses may be divided, by physicochemical properties, into enteroviruses, cardioviruses, caliciviruses, rhinoviruses and foot-and-mouth diseases viruses. In the control young ddY mice, however, the overloaded mesangial human IgA quickly disappeared, presenting no appreciable mesangial deposition of autologous IgA. Consequently, Ethibloc duct occlusion does not seem to be a superior alternative to other methods of producing exocrine atrophy in organs intended for transplantation. Disorders of spermatogenic and androgenic functions in varicocele.
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We evaluated the mean arterial pressure (MAP), heart rate (HR) and regional blood flow (BF) in response to NPY in normal and diabetic rats. These findings are similar to the ultrastructural features previously described as being specific for gastrointestinal adenocarcinomas metastatic to lung. In addition, cortical alpha-activity was examined to test whether gamma-band activity might reflect changes in harmonics of alpha waves. We find that it is indeed possible to reproduce behavior similar to that seen in experiments, with the data for cos theta plotted versus sigmalv falling in a narrow band which could almost be interpreted as a smooth curve. Segments of equine jejunum were subjected to ischaemia for 1 h, and recovered for 4 h in Ussing chambers. Further analysis of the IgG response revealed production of IgG1 and IgG2 antibodies by all patient groups, while an IgG3 response was seen only in survivors of septicemic infection. Thus, although these results support the view that cytoplasmic receptors and the capacity to transport androgens are closely linked phenotypic markers of intracellular steroid hormone action, they suggest that the control of androgen concentration in the nucleus is achieved in a more intricate fashion than simply through a dependence on the presumed translocation of 4.4 S androgen-receptor complex into the nucleus. Spontaneous activity, consisting primarily of complex repetitive discharges (pseudomyotonic discharges), was found in all dogs tested, but was most prominent in dogs greater than or equal to 10 weeks old. 100) with an average follow up of 7 years (range 5 years to 10 years 4 months), 12 of whom recovered to stage I disability by the NYHA classification after the first postoperative year. Hydrocarbon-grown organisms were characterized by the presence of intracellular electron-transparent inclusions which in many cases appeared membrane-bound.
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In contrast, HRP was restricted to the apical region of enterocytes in controls. Salutary effect of tedisamil on post-ischemic recovery rat heart: involvement of sarcolemmal (Na,K)-ATPase. Even when CT6 was recloned by a limiting dilution, no unresponsive clone to PMA was obtained, whereas several clones unresponsive to LPS were obtained. Two of these forms were observed in all tissues examined, while several others were uniquely observed in cardiac muscle and brain. From these observations a close link between the Gly I and the adaptive-response as well as the split-dose effect is speculated. The synergistic action of penicillin and streptomycin on Endameba histolytica cultures.
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In the case presented, the fibrosis first became manifest in the pelvis and simulated metastatic carcinoma of the cervix. In two women from group B, the serum HCV levels were undetectable during follow up. A comparative study of enzymatic digestion profiles of apolipoprotein B from four human subjects. They all became acutely ill with fever, chills and severe headache 1-10 days after return to Norway. The expression of BCL-x, a BCL2-related protein that is a potent inhibitor of apoptosis, was investigated by immunohistochemical and immunoblot methods in 43 primary untreated breast carcinomas, in conjunction with BCL2 and TP53.
National Kidney Foundation-Dialysis Outcomes Quality Initiative. Although plasmid pD10 was stably maintained in the host bacterium, the introduced strain did not enhance the degradation of 3-chlorobenzoate in the ASU. Three doses of estradiol produced a more pronounced protection with a lower number of E. It is therefore suggested that chemical or enzymatic methods be used to inactivate serum inhibitors and that standard virus be used in the HAI test for the currently circulating H3N2 viruses. Application of a new residual chlorine method to effluent chlorination. Moreover, the alterations of rDNA transcription by the hormone is effected by a factor which elutes with fraction TFIA. No biochemical, hematologic or histopathologic changes were observed.
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Virus development in enucleate cells: echovirus, poliovirus, pseudorabies virus, reovirus, respiratory syncytial virus and Semliki Forest virus. Hydroxyurea, fluorodeoxyuridine, and 3 mM thymidine all stimulated nerve outgrowth in the absence of exogenous NGF. A sample of 125 students completed the revised Ways of Coping Questionnaire, the Academic Problem-Solving Inventory, and measures of state and trait test anxiety. Cytochemical changes in lactate dehydrogenase isoenzymes in human brain tumours. Preventative foot care programs for diabetic unilateral amputees should therefore place greater emphasis on peripheral vascular assessment to identify patients at risk and on the development of timely intervention strategies. Effect of Biseptol 480 on the cells of the exocrine part of the pancreas after surgical removal of the hepatic lobe. Melatonin-treated hamsters exhibited increased splenic lymphoproliferative responses to a polyclonal T-cell mitogen (concanavalin A (Con-A)), but decreased proliferation following stimulation with a polyclonal B-cell mitogen (lipopolysaccharide). Extensive setting-up of sanitary standards has no significant positive effect on natural and technological environment. Some of the processes occurring in the diabetic person may, however, be of major importance in initiating and maintaining conditions for the evolution of microvascular disease. Primary repair of 2 patients with large upper arm defects with the bilobed fasciocutaneous flap is reported.
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Eggs from -6 to 21 days and 58 to 64 days postinoculation were incubated. In addition, since an unconjugated de-O-acetylated (dOA) GCMP vaccine was previously shown to be highly immunogenic in humans, we had chosen this dOA form to couple with TT by reductive amination for clinical evaluation. Aminolaevulinic acid (ALA) is an endogenous substrate in the haem biosynthetic pathway. The results of radiological and endoscopic examination of 173 patients with gastric ulcerations (71 of cancerous and 102 of ulcerative etiology) were studied. To more strictly verify these preliminary data, a double-blind placebo controlled study is in progress. Bleeding is one of the most frequent complications leading to discontinuation of an otherwise effective form of long-term contraception and family spacing.
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Morphostatistical analysis of the lymphocytic infiltration intensity and mitotic activity in 34 colon villous tumours is performed depending on the degree of dysplasia, the presence or the absence of invasive growth. A further 20 represent helical regions which definitely exist, but where the detailed base-pairing is still open to discussion. However, nearly all of these problems may be avoided if a resonance technique is used, and all of the elastic constants may be determined with a single measurement. Autologous as well as homologous bone implants were added as needed. Superoxide also gives rise to breaks in DNA suppressible by both superoxide dismutase and catalase. The origin of this widespread leiomyosarcomatosis of the gastrointestinal system is discussed. The propagation of noise in digitized images arrived at by algebraic manipulation of two images has been investigated. Inverted papilloma of the nose and paranasal sinuses--diagnosis, surgical procedure and studies of cytokeratin profile.
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(7) What is to be learned from tobacco and other risky commodities about the importance of supply?. To investigate the direct influence of high glucose on endothelial cell structure and possible pharmacologic effects, seven different experimental protocols were carried out on endothelial cells in culture. Unusual pulmonary complications resulting from prolonged lodging of nonopaque foreign body in left main stem bronchus. When the pressor effects of phenylephrine were opposed by administration of diazoxide or phentolamine, the inhibitory effects of phenylephrine on both HR and VO2 were abolished. Here we report on the use of a replication defective HSV-1 mutant vector (DZ) deleted for the essential immediate early (IE) gene ICP4 for studies of reporter gene transfer and expression following direct inoculation of mouse skeletal muscle. Maximum capacity athletics and their problems from the medical viewpoint.
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The relationship between hookworm infection intensity and hemoglobin concentration is evident in epidemiologic studies, but may be apparent only above a threshold worm burden that is related to the iron stores of the population. These studies suggest that NO-related signaling pathways may mediate SDF1 alpha-induced chemotaxis, but not mitogen-activated protein kinase activation. The proliferation of each examined tumor cell line was significantly inhibited (IC50 values ranged from 0.2 to 8.1 micrograms/ml) during the continuous exposure of tumor cells to 1-18 for 48 hours, respectively. Sealing of anastomoses has previously been tested with several methods, including sealing with liquid fibrin glue. Enzymatic formation of uridine diphosphate N-acetyl-D-mannosamine. These data indicate that the three divisions of domestic fowl kidneys are structurally homologous on a per gram kidney weight basis, suggesting the separate divisions also are functionally homologous. Overall study of 20 years of curative and prophylactic peripheral retinoschisis treatment in 60 cases of sex linked congenital retinoschisis.