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Alpam (Alprazolam)

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Alpam is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpam is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aldep, Alpkair, Alprawin, Alprose, Alproz, Alsert, Alzolam, Alzorix, Alzotime, Ambutech, Andep, Benzolam, Dipra, Emcalm, Erazol, Flunix, Fluxozam, Imprax, Jolistar, Maxorest, Meloprax, Samitol, Tenlax, Tenolam, Visram, Xycalm, Zallpam, Zeprax, Zolam, Zoldac, Zoltweet, Zotam

Similar Products:
Robaxin, Detrol, Ambien, Lunesta, Duphaston

Also known as: Alprazolam


{name} XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

{name} XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

{name} XR may also be used for other purposes not listed in this medication guide.


Take this medication by mouth as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists or worsens.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking Alpam, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alpam is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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Antibodies to TR2 (herpesvirus entry mediator), a new member of the TNF receptor superfamily, block T cell proliferation, expression of activation markers, and production of cytokines. Respiratory infections in early life are associated with risk for wheezing bronchiolitis, especially in children at high risk of atopy. Studies indicate that these changes, whether combined or not with peripheral retinal degenerations such as lattice areas, carry risk for subsequent retinal breaks or detachment. Our results support the need for prevention programs that are targeted to mitigate the risks for BBF exposure posed by high blood loss during surgery (eg, use of blunt suture needles and a neutral zone for passing surgical equipment) and prolonged duration of surgery (eg, double gloving to defend against the risk of glove perforation associated with long surgery). However, individuals with the same genetic disorder often show remarkable differences in clinical severity, a finding generally attributed to the genetic background. To evaluate the effectiveness of treatment of hepatocellular carcinoma (HCC) before liver transplantation (LT) and its influence on survival and tumor recurrence in patients transplanted for HCC.

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Most strikingly, a subset of duplicated genes is enriched among the recently duplicated genes involved in immune or sensory response pathways. Functional outcomes following percutaneous surgery in the solitary kidney. Although the incidence of acute rejection has considerably decreased, renal toxicity of the calcineurin inhibitors remains problematic. Magnetic resonance imaging of a 39-year-old woman who presented with an abdominal mass revealed a tumor with hemorrhagic lesions extending from the intrauterine space to the subserosa. Rapamycin: distribution, pharmacokinetics and therapeutic range investigations: an update. Often, disabled people are offered the option to control assistive devices that will facilitate the recovery of independence and capability in their daily lives. These results suggest that RACK1 may act as a key bridging factor in adiponectin signaling transduction through interacting with AdipoR1. To develop clinical practice guidelines for the identification, evaluation and treatment of chronic neuropathic pain in spinal cord injury patients. C81 appears to be a useful tool for elucidation of the mechanism of apoptosis induced by expression of Vpr protein.

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Eighteen patients were surgically treated for one-level, six for two-level and one for three-level disease. Polyps were not found to be predictive of QOL or endoscopic outcome. Construction of two-stranded alpha-helix peptides based on influenza virus M1 protein selectively bound to RNA. The objective of the present study is to present a case of a 48-year-old woman with leiomyomatosis and multiple pulmonary metastases. Clinical performance of a diode laser fluorescence device for the detection of occlusal caries in primary teeth. Modulatory effects of the acid polysaccharide fraction from one of anamorph of Cordyceps sinensis on Ana-1 cells. This approach, combining an adaptive (learning) fuzzy inference system and an interaction type classifier to predict transcriptional regulatory networks, was named AdaFuzzy. It is therefore suitable for chronic recordings with electrode arrays where typically temporal and spatial nonstationarity of the extracellular waveforms complicates the estimation of the true action potential. This study finds that increase in diameter with time of the droplet of tapered nanowires results primarily from gradual incorporation of oversupplied nanowire species into the FECA-mediated droplet, which is supported by experiments. We conclude that Hrs is a positive regulator of VEGF-R2 and IR signaling and that ectopic expression of Hrs protects both VEGF-R2 and IR from degradation.

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We report a case of AOLPA from the aorta with partial anomalous pulmonary venous return (PAPVR) in a 3.2 kg infant. The antiproliferative effects of 1,25(OH)2D3 are reported to be mediated through the genomic signaling pathway by binding to a specific high affinity receptor protein, the 1,25-dihydroxyvitamin D3 receptor (VDR). Polarization is an important addition to spectral imaging in detecting and identifying objects of interest, and simple linear polarization measurements are often inadequate. Ten patients who received helmet field irradiation at our institution were selected for study. Ballistocardiography is a non-invasive technique for the assessment of cardiac function. Appendiceal intussusception to the cecum caused by mucocele of the appendix: Laparoscopic approach. The relevance of significantly altered methylation profiles was validated in an independent clinical trial cohort. Then the experimental perspective is presented, with the biophysical mechanisms and modalities of open-loop electrical stimulation, and the potential benefits of closed-loop control for epilepsy.

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Increased STAT3 phosphorylation was observed in either HER2 overexpressing cells or HRG-induced cells. Different prophylactic regimens for the management of severe hemophilia are described along with the use of adjuvant treatment options to achieve hemostasis. The initial conservative treatment of injections in the conflict zone and the intervertebral joints was insufficient. For our study, we conducted an extensive policy review and 17 in-depth interviews with 26 individuals. To compare the antihypertensive efficacy and tolerability of telmisartan 80 mg with valsartan 80 mg throughout a 24 h dosing interval. Endoscopic grading of GEFV and the presence of severe reflux esophagitis are predisposing factors for failure of PEG to reduce GER in mechanically ventilated patients. Only when we suppressed autophagy in the skeletal muscle of the GAA KO mice did we realize that the excess of autophagy manifests as a functional deficiency. TLR-7 receptor and HCV relationship in patients with LP could not be confirmed by this study. Stent-assisted recanalisation has a high technical success rate with good clinical results as a bailout procedure for the management of acute limb ischaemia in patients, considered unfit for thrombolysis or in patients with failed surgical recanalisation.

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The iphACBDR genes constitute a single transcriptional unit, and transcription of the iph catabolic operon was induced during growth of E6 on IPA. Assessing Equity in the Provision of Primary Healthcare Centers in Buenos Aires Province (Argentina): A Stochastic Frontier Analysis. Based on the observation that women who were current smokers, obese, or experiencing a substantial degree of psychological distress were significantly less likely to adhere to recommended screening guidelines, we suggest that healthcare providers pay particular attention to the screening needs of these more vulnerable women. By routine radiography and sonography in supine position this rare condition may be misinterpreted as renal lithiasis for which an unnecessary surgical intervention may be performed as it happened in our two cases that are presented here. Proceedings of the European Cancer Prevention consensus meeting. Enhanced ATM kinase-dependent phosphorylation of Nbs1 on serine 343 (S343) in response to genotoxic treatment was detected in leukemia cells expressing BCR/ABL and other FTKs in comparison to normal counterparts stimulated with IL-3, GM-CSF, and SCF. Personal history of autoimmune disorder for patients and controls, family history of autoimmune disorder for vulval LS and LP cohorts, and an autoantibody screen. However, by repeated cycles of myocardial ischemia/reperfusion coronary t-PA release progressively declines. By contrast, the existence of systemic sclerosis-specific autoantibodies, nail fold bleeding, digital ulcer/digital pitting scar or telangiectasia is highly suggestive of systemic sclerosis. This article suggests that a major reason for this is that the discussion has focused exclusively on the nature and status of the material resources, and that the nature and role of the medical profession have been entirely ignored.

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Adult oligodendrocytes were protected by these low doses of HSP90 inhibitors in a similar fashion to perinatal cells. Women in general practice: responding to the sexual division of labour?. In July 2008, the fifth and last meeting of the Mast Cells and Chronic Inflammatory Diseases (MCCID) network was hosted by Axel Lorentz and Stephan Bischoff at the University of Hohenheim, in the Aula of the Chateau Hohenheim, Stuttgart. The expression of E-cadherin and vimentin was detected by Western blot. We compared the clinical characteristics, histological findings, and genotypes of the angiotensin-converting enzyme (ACE) gene and plasminogen activator inhibitor-1 gene between IgAN and N-IgAN patients. On the basis of the quantification of MP1-p14, we demonstrate the importance to assess completeness of protein digestion and discuss the use of peptides containing labile amino acids and the choice of instrumentation. Emergency conflict-related psychosocial interventions in Sierra Leone and Uganda: lessons from Medecins Sans Frontieres. In Experiment III, mice received 30 mg/kg cocaine 30 min pre-training and pre-test.

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Also discussed are implications for presymptomatic testing of the BRCA1 and BRCA2 genes for adult-onset breast and ovarian cancer. The highly conserved RNAs, microRNAs (miRNAs), are a class of small single stranded noncoding RNAs that function through translational repression of specific target mRNAs. Electrophysiological features of inherited demyelinating neuropathies: A reappraisal in the era of molecular diagnosis. Surprisingly noroxin tablet , all these imaging parameters concur to the conclusion that both glycolytic tumors and oxidative tumors presented a similar response to DCA. Several approaches to extend gastric residence time have been tried. Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice.

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Partial fundoplications have been popularized by their lower risk of mechanical side effects. YFP-myosin tail fusions provide specific labeling for vesicles of unknown composition, whose identity can be investigated in future studies. However, when the cue stimuli were replaced with green or red circles to ease interpretation, patients showed similar false alarm rates to controls. Due to the burden of influenza hospitalizations among children, inactivated influenza vaccine is now routinely recommended for children age 6 to 59 months. Closely related regulons are found in other species of Shigella and in enteroinvasive Escherichia coli. The high levels of circulating LDL, which result from the overproduction of VLDL and impaired lipoprotein lipase activity, are glycated in the presence of elevated blood glucose. None of the patients had serious changes in the blood pressure or respiratory status attributable to the use of midazolam. Most Americans will be afflicted by some form of spine-related pain in their lifetime. We demonstrate that 125I-Fas2 binds very specifically to the NMJs of mouse sternomastoid muscles, with very little binding to other regions in the muscles. In the context of a larger study on morphological changes of deep sole ulcers, claws with Rusterholz ulcer (RU) were investigated to describe the varied pathological changes of the RU.

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The current trend towards discharging patients after culture conversion would reduce the psycho-social impacts of prolonged isolation and potentially reduce the risk of occupational TB from prolonged contact with MDR-TB patients. Oscillations in the minute range seem to be more common and some might be related to turgor regulation and ion uptake comparable to the situation in Desmodium. The suitability of the can i buy nizoral over the counter candidate reference preparations to serve as working references in the tests for distribution of the molecular size, anticomplementary activity and Fc function, in accordance with the specifications of the Ph. Independent risk factors for endometritis were determined by means of multivariable logistic regression. Does grade level relate to school-based youth health center utilization among male youth?. In the present study we examined the serotonergic modulation of GABAergic and glutamatergic synaptic transmission in rat midbrain PAG slices in vitro. They are related to a sinew chronic antagonism with an anatomic bony ground and they generally develop in a spontaneous resolution with a macrophagic resorption. We find that in the Australian freshwater crayfish Cherax destructor, neuropil volumes of the olfactory centers increase linearly with body size over the entire size range of animals found in their natural habitat.

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Hydraulic dilation (URETEROMAT): effective and safe ureteroscopy. A growing literature supports the use of certain medications for managing pediatric aggression. Preservation of bone mineral density, a surrogate for fracture risk, has been demonstrated in randomized controlled trials of bisphosphonates. Primary culture of rat MEEC was positively stained by cytokeratin antibody, but not by vimentin, indicating the epithelial origin of the cultured cells. A 66-year-old man with recurrent stroke within a short period of time was referred to our department from the neurology department to rule out any malignancy. The physiologic implication of these observations is briefly discussed. Brg1 knockdown in MLE-15 cells greatly decreases H3K4me3 levels at the Sftpb promoter region and expression of the Sftpb gene. Development of immunity to Mecistocirrus digitatus (Nematoda: Trichostrongylidae) in calves.

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Polycyclic aromatic hydrocarbons (PAH) are important environmental contaminants which may lead to increased levels of neoplastic aberrations or tumours in fish liver. The role of ENSO may be obscured by local climate heterogeneity, insufficient data, randomly coincident outbreaks, and other, potentially stronger, intrinsic factors regulating transmission dynamics. Novel fusapyrone analogs, deoxyneofusapyrone and 7-desmethyldeoxyneofusapyrone were isolated from a pathogenic fungus, Verticillium dahliae, which causes Verticillium wilt disease in Helianthus annuus. Radiological protection from radioactive waste management in existing exposure situations resulting from a nuclear accident. To obtain a general overview of metabolism, we ultram dosage describe the use of deuterium oxide (D2O) to measure deuterium incorporation into the intracellular metabolites of two physiologically diverse cyanobacteria: a terrestrial filamentous strain (Microcoleus vaginatus PCC 9802) and a euryhaline unicellular strain (Synechococcus sp. In this way, the increased expression of human interferon alpha (hIFN-alpha) is associated with acute viral infections, inflammatory disorders and several autoimmune illnesses, where the cytokine may be a factor in either initiating or maintaining the disease.

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A 48-year-old Caucasian woman presented with headache and vomiting followed by cerebellar signs and confusion. Human SA/STAG proteins, homologues of the yeast Irr1/Scc3 cohesin, are the least studied constituents of the sister chromatid cohesion complex crucial for proper chromosome segregation. Relevant themes were abstracted from the interviews by a standardized iterative process. The model is based on the Hodgkin-Huxley (HH) model, which enables it to simulate the complex dynamics of MUIPs, such as the interactions between motor unit common drive and MUIP correlation (motor unit synchrony). IBI scores were statistically lower for the urban versus the agricultural sites.

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New restorative therapies for Parkinson disease, aimed at delivering drugs or cells to the substantia nigra (SN), are becoming available. Differential effects of tri-n-butylstannyl benzoates on induction of apoptosis in K562 and MCF-7 cells. The population remains susceptible to invasion by a less virulent phenotype that responds to soft selection, however. Chloroquine increases low-density lipoprotein removal from plasma in systemic lupus patients. One of them underwent range expansion colonizing different continents, including Africa, where it mixed with another, local lineage represented today by a large fraction of African-specific haplotypes. Among its receptors, VEGFR-2 seems to be the most intimately associated with mitogenic activities, cell migration, vascular permeability, and survival of endothelial cells. Wexner score, Fecal Incontinence Quality of Life (FIQL) questionnaire, and Self-rated Health Measurement Scale Version 1.0 (SRHMS) score were used to evaluate life quality of the patients.

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Using voltage-sensitive dye recording to image the functional development of neuronal circuits in vertebrate embryos. Single-cycle induction chemotherapy for resectable advanced hypopharyngeal cancer. The increase in image quality is substantial when the proposed method is compared to conventional denoising protocols. Only gatifloxacin reached aqueous concentrations greater than the minimal inhibitory concentration for B. The concentration of the neuronal enriched ganglioside GD1a was significantly lower in the cerebrum/brainstem of Mecp2 (tm1.1Bird) mice than in that of age matched controls, but was not reduced in the Mecp2 (308/y) mice. The clinical records of 59 patients, aged 6 to 90 years old (35 male), with active gastrointestinal bleeding subjected to a 99mTc red blood cell scintigraphy were reviewed. Multiscale approach to the structural study of water confined in MCM41. Why MRI of brain is superior to CT in multiple neurocysticercosis?. Medial Prefrontal Cortex-Pontine Nuclei Projections Modulate Suboptimal Cue-Induced Associative Motor Learning.

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