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Alprac (Alprazolam)
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Alprac

Alprac is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprac, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprac is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Almee, Alpkair, Alzac, Alzocum, Alzokam, Alzoset, Anquil, Anxigo, Anxorel, Belfa, Calmef, Censir, Cozac, Depsolam, Erazol, Fludep, Fluti, Hipose, Isorest, Kaprolam, Meloprax, Notence, Samrox, Selam, Selamb, Silam, Suzilam, Tagat, Tensyn, Trustin, Xanti, Zallpam, Zolam, Zolent, Zopax

Similar Products:
Calan, Microzide, Glucotrol, Wellbutrin, Artane, Cozaar

Also known as: Alprazolam

Description

{name} XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

{name} XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

{name} XR may also be used for other purposes not listed in this medication guide.

Dosage

Take Alprac exactly as prescribed by your doctor. Follow all directions on your prescription label. Never use Alprac in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Alprac may be habit-forming. Never share Alprac with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Do not crush, chew, or break a Alprac extended-release tablet. Swallow the tablet whole. Call your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms. Do not stop using Alprac suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Overdose

If you have been prescribed Alprac for medical reasons, the best way to avoid a Alprac overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprac consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprac XR dosage information

Side effects

The most common side effects associated with Alprac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Draft genome sequence of an aminoglycoside-resistant RmtG-producing Pseudomonas aeruginosa ST235 isolated from a cystic fibrosis patient. A Magnetic Resin System was used to capture a consistent amount of DNA from embryo biopsy and wild felid hairs. Linear regression analyses showed significant declines in FDLs at both frequencies as age increased. In conditions of hypoxia it leads to an increase in several growth factor levels. Measures have been recorded for different positions of the forearm. Contractile responses to histamine or Dermatophagoides pteronyssinus (D. Sexual objectification of gay men of colour in the USA produces a white sexual community. New diagnostic criteria are proposed for recurring migraine-associated vertigo.

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Effect of the level of iodine in the diet of pregnant ewes on the concentration of immunoglobulin G in the plasma of neonatal lambs following the consumption of colostrum. The enhanced VEGF/flk-1 in the epithelium may be identified as one of the parameters in judging malignant transformation of NIPs. Previous studies underestimate BMAA concentrations in cycad flour. Fixation location and stimulus presentation were controlled using an eye-tracker linked to a fixation-contingent display and performance was assessed using a forced-choice task to suppress confounding effects of guesswork. Capsaicin inhibited protein synthesis in TRPV1-expressing HEK cells with an IC(50) of 15.6nM and depolymerized microtubules within 10min after exposure. From August 2003 to October 2006, 93 (84.5 percent) patients with ectopic pregnancy were successfully treated with intramuscular methotrexate. Reproductive considerations and pregnancy after bariatric surgery: current evidence and recommendations. Special care was paid to allow self-aligned assembly for repeatability and modularity for combining multiple platforms for a sensorised floor. We offer the view that this tumult is the result of the intersecting behaviors of the many single-celled creatures (i.e., neurons, glia, and progenitors) that inhabit brains. Idiopathic macular holes have one of two patterns early after surgical closure, simple closure or a bridge formation.

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Seven steps to assure the best possible treatment of persons with glaucoma or suspected of having glaucoma. Using the skills, rules, and knowledge distinction we identify cognitive control needed. The purpose of this study was to determine the safety and immune responses of pre-operative personalized peptide vaccine for patients with localized prostate cancer. The correlates of mammalian sleep have been investigated previously in at least eight comparative studies in an effort to illuminate the functions of sleep. The vast majority of lichenicolous fungi are relatively host-specific, nonvirulent ascomycetes and heterobasidiomycetes. A probit analysis was used to calculate the lethal concentrations (LC50 and LC95) for each product at each salinity. Successful use of continuous intravenous prostacyclin in a patient with severe portopulmonary hypertension.

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In addition, the arterial and venous blood flow significantly decreased. Click and Fluoresce: A Bioorthogonally Activated Smart Probe for Wash-Free Fluorescent Labeling of Biomolecules. The origin of the material was tea leaves, which were ground, sieved through a 106-microm mesh, homogenized, and then subdivided into amber glass bottles. To investigate a unique and critical step in retroviral gene expression not yet targeted for anti-viral therapy and to validate its potential as a site for anti-HIV intervention with a new group of therapeutic drugs. Health policy-making in central and eastern Europe: lessons from the inaction on injuries?.

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Findings signify the need for counseling and nurse-based intervention and prevention services geared at preparing pregnant adolescents for motherhood. Results of randomized trials comparing the addition of thrombolytic therapy to standard heparin therapy for treatment of submassive pulmonary embolism fail to show any significant differences in clinically important outcomes. When exposed to metals, singly, in solution for 24 h, cells of both strains accumulated the metals. The three detachment mechanisms analyzed represented various physical and biological influences hypothesized to affect biofilm detachment. In this respect, efforts will be needed to evaluate promising innovative therapies in prospective clinical trials. The p75 pan-neurotrophin receptor controls neuronal cell fate after its selective activation by immature and mature isoforms of all neurotrophins. Abdominal aortic aneurysms (AAAs) are characterised by chronic transmural inflammation.

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This study was conducted to investigate the association between prolonged breastfeeding and early childhood caries(ECC) with adjustment for important confounders, using hieraschical approach. This PDA was developed in accordance with international patient decision aid standards. nodorum rDNA tandem repeat to different extents depending on their genomic contexts. Pinch1 mutants also exhibit multiple deficiencies in cranial neural crest-derived structures. A 14- to 16-cm-long, 15- to 16-mm-wide buccal/lingual mucosa graft was harvested and sutured dorsally at the site of urethrotomy, and then distally at the meatus along with meatoplasty. Halophilic beta-lactamase as a new solubility- and folding-enhancing tag protein: production of native human interleukin 1alpha and human neutrophil alpha-defensin.

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Strategy for educating senior dermatological residents in mycology. The costs and risks associated with these supplements are low, however, and physicians may choose to recommend vitamin E, folate and/or vitamin C supplementation pending conclusive evidence from clinical trials. A similar correlation between low p53 levels and Aurora-A gene deletions and expression is found in human breast cancer cell lines. Hospital electronic medical record-based public health surveillance system deployed during the 2002 Winter Olympic Games. There was a trend for patients treated with CPC to have a higher incidence of graft failure, glaucoma failure, hypotony, and visual loss by more than one line, although this was not statistically significant. The corresponding optimum solvent compositions to extract chemical substances for these three mobile phases were ethanol/acetone (25:75 v/v/v) and dichloromethane/acetone (70:30 v/v) mixtures, and pure dichloromethane, respectively. As a consequence of this, the assembly of the EC-SOD tetramers produces molecules with variable activity and may represent a way to regulate the antioxidant level in the extracellular space. Its indications in medicine are considered as primary, complementary or experimental depending on the evidence based effects. ER aminopeptidase 1 (ERAP1) has been demonstrated to be a critical determinant of the immune response by generating mature antigenic epitopes from peptide precursors that arrive into the ER originating primarily from intracellular proteins degraded by the proteasome.

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Chiropractic research center in the midwest United States that is not a fee-for-service clinic. We searched MEDLINE and EMBASE for interventional and observational clinical trials focusing on RFS, excluding case reports and reviews. Using simulation-based Markov chain Monte Carlo methods for simulating parameters from the posterior distribution, an efficient and dependable algorithm is implemented. A free-draining, freely jointed bead-rod chain was used to model the polyelectrolyte, and electrostatic interactions were incorporated using a screened Coulombic potential with the excluded volume accounted for by a hard-sphere potential. Regardless of the initial larval age, lower antioxidant activities were observed in the RJ harvested later than 24 h except for the activity of superoxide dismutase. Monocyte chemoattractant protein-1 (MCP-1) is a member of the CC subfamily of chemokines. In this case, reversible bonding of the device to the cover glass makes that possible.

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Telomerase is the enzyme that is responsible for maintaining telomere length in human germ cells, tumor cells, and immortalized cells. Five hundred and fifty-seven patients with severe asthma were enrolled. In a prospective cohort study of 46,295 men, a Western dietary pattern was associated with increased risk of diverticulitis, and a prudent pattern was associated with decreased risk. However, a concatenated and a consensus analysis, combining the genes, allowed better discrimination of each strain to the species level, and the increase in sequence size also led to greater tree robustness. These observations reveal distinct functions for these two classes of the TGF-beta family during early Xenopus development, and in doing so identify a new role for activin B during gastrulation.

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Acute parasitic and other infectious myelopathies in the tropics: 26 cases at the University Hospital in Conakry. Are we overconcerned about secondary hyperparathyroidism and underestimating the more common secondary hypoparathyroidism in our dialysis patients?. Twelve patients were identified, and all had a history of tuberculous pleuritis or surgical intervention for TB. In conclusion, TGA inhibits in-vitro maturation of mice oocytes and affects chromosomal arrangement and spindle configuration. Consistent rewarding or aversive effects of the electrical stimulation of the lateral parabrachial complex. Further, whereas nearly all prior studies of MREs focused on those located in promoters, we demonstrate binding of MTF-1 to MREs located downstream of the transcription start sites in the human and murine selenoprotein H genes. Seven spines (C0-C4) were evaluated in flexion-extension, left-right bending, and left-right axial rotation in a cadaveric C1-C2 fixation model. Although the properties of neurite (particularly axonal) outgrowth have been extensively studied in retinal ganglion cells, comparatively little work has been done with other retinal neurons.

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Gender may provide an explanation for non-participation in the healthcare system. Phenol is a highly toxic and norethindrone and ethinyl estradiol tablets carcinogenic compound and its biodegradation is very important to meet the environmental regulations. Cryoglobulins in nonalcoholic Fatty-liver disease: what is the association?. We queried the National Trauma Data Bank version 6.1 and calculated ultrasound rates and DVT rates per trauma center. Neurobehavioral alterations in rats exposed to acrylonitrile in drinking water. The team developed a disease management program that included comprehensive inpatient education, as well as an outpatient telephonic program to reinforce education after discharge. Ultrafast electron diffraction: structural dynamics of molecular rearrangement in the NO release from nitrobenzene. A speech appliance may prevent hypernasality, nasal emission of air, or both associated with VPI because of mechanical obturation of the velopharynx and an alteration in velopharyngeal function. The ability to breastfeed and continue the practice requires dedication, commitment, persistence and support.

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The greatest number of thrips was noticed during flowering period on Valeriana officinalis L., and Hypericum perforatum L. Our results demonstrate that SGlc can increase ALP activity, collagen synthesis, osteocalcin secretion, and mineralization in osteoblastic cells in vitro. Since its launch on 20 November 2004, the Swift mission has been detecting approximately 100 gamma-ray bursts (GRBs) each year, and immediately (within approx. Collectively, this volume examines staff perceptions of program needs, organizational readiness for change (based on pressures, resources, staff attributes, and organizational climate), quality of workshop training, subsequent utilization of training materials, and client self-report of treatment engagement. Clinical description of seizures in patients with systemic lupus erythematosus. ProSeal Laryngeal Mask Airway in a myasthenia gravis patient for thymectomy. We retrospectively reviewed the charts of 87 patients who underwent 91 percutaneous nephrolithotomy procedures at our hospital from April 2004 to June 2005, during which a holmium-YAG laser with a self-made fiber guider was used for lithotripsy. Development of a three-dimensional in vitro model for longitudinal observation of cell behavior: monitoring by magnetic resonance imaging and optical imaging.

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The effects of inherent and passive protection measures are also assessed. Spiggin mRNA was significantly higher in kidneys of field-caught males compared to females by greater than five orders of magnitude while ARbeta levels were only 1.4-fold higher in males. The chemopreventive effects of cabbage may be connected with modulation of the activity of phase I and II detoxification enzymes and other mechanisms triggered by glucosinolates and products of their decomposition, which are formed as a result of hydrolysis catalyzed by the enzyme myrosinase. They may have therapeutic potential for MS patients that have anti-HSP90 autoantibodies and provide a novel strategy for therapeutic intervention with HSP90 inhibitors. The requirement of Y-chromosome activity for the differentiation of somatic cells and germ cells was studied in the fetal gonads of X/XSxra mouse embryos where the activity of the Sxra fragment of the Y chromosome is influenced by the inactivation and reactivation of the X chromosome. Moreover, the 5-HT(1A) receptor regulates several transduction mechanisms such as kinases and immediate early genes implicated in memory formation. The inherent variability of the biological systems used for production of vaccines is much greater than that encountered in the production of pharmaceuticals. High-density culture of CHO-K1 cells was successfully performed using the HAPC sheet bed in a 500 ml spinner flask over a 21-day culture period.

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The local horizontal divergence is studied and comparisons are made with two-dimensional kinematic simulation. Local Versus General Anesthesia in Pediatric Renal Biopsy: Which is Associated With Better Outcome?. We conclude that three-dimensional echocardiography measurement of right ventricular volumes correlates closely with magnetic resonance imaging in children with operated congenital heart disease and may allow accurate serial evaluation in these patients. Three times weekly tacrolimus ointment reduces relapse in stabilized atopic dermatitis: a new paradigm for use. Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan. Stimulus-level learning modulated cortical dynamics earlier in the temporal-processing stream relative to stimulus-decision and stimulus-response learning. The effects of antidepressant drugs on non-REM and REM sleep are discussed in relation to their use in insomnia comorbid with depression. We will discuss the role of histone modifications as well as their displacement or exchange in nucleotide excision repair and make a comparison with their requirement in transcription and double strand break repair. The acoustic propagation environment was reconstructed from this set in conjunction with bottom parameters extracted by use of acoustic inversion techniques.

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These libraries were used for genome-wide alignment and RNA-fold analysis for possible prediction of potential miRs and Tasi-Rs. Furthermore, rTSIF could down-regulate type 2-oriented immune responses. Liver stiffness measurements with supersonic shear wave elastography in the diagnosis of biliary atresia: a comparative study with grey-scale US. Several trinucleotides known to have high propensity for major groove compression are found much more frequently in the regions downstream of the transcriptional start point, while the upstream regions contain more low-bendability triplets. Chromatin immunoprecipitation on the myogenin promoter showed that PAX3/FOXO1A or PAX7/FOXO1A did not prevent MyoD from binding. To compare measures of retention based on both clinic visit data and HIV laboratory surveillance data. Early postoperative hypotony after 25-gauge sutureless vitrectomy with straight incisions. This mutant confers complete cross protection against subsequent infection by the parental ZYMV (ZG) strain. Formal procedures that guide multiplex assay configuration, analytical validation, and quality control are needed before broad application of multiplexed arrays can occur in the in vitro diagnostic market.

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A combination of vincristine, doxorubicin, and cyclophosphamide alternating with cisplatin and etoposide (VAC/PE) was administered to 14 patients during the years 1988-1996 according to a prospective study protocol. This was subsequently reported as endometriosis by histological examination. A single-blind randomized controlled trial, with an 8-month follow-up. It is of particular concern because strains in some geographic areas are capable of producing toxins with implications for human and animal health. Additionally, identification of new therapeutic targets is a priority. The control plasmid pCDNA3.1 (-) was transfected by the same method. Electrostatic control of the overall shape of calmodulin: numerical calculations. Magnetic ground state of single and coupled permalloy rectangles. Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan children.

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Second-generation agents were very heavily evaluated in mechanistic studies and formed the basis for a number of oncology portfolios of big pharmaceutical companies. We aimed to describe the pathogenic and immunological characteristics of this illness. Cost/effectiveness comparison of the vaccine campaign and reduction of sick leave, after vaccination against influenza among the Clermont-Ferrand University Hospital staff. As a result, these structures plausibly could not only accelerate the dehydration process for new chemical bond formation but also facilitate further self-organization can you take zyrtec and cough syrup and prebiotic evolution in a dynamic manner. Mammalian innate immune cells produce reactive oxygen species (ROS) in the oxidative burst reaction to destroy invading microbial pathogens. For colorectal screening patients a mean gain of life time was previously calculated of about 30-50 days. Mitochondria: omega-3 in the route of mitochondrial reactive oxygen species. All great apes exhibit slow life histories and we infer this to be true of the last common ancestor of Pan-Homo and the stem hominin. These findings suggest that peptides possessing both enhanced mobility in the bacterial outer membrane and spatial structure facilitating its interactions with the membrane-water interface may provide excellent structural motifs to develop new antimicrobials that can overcome antibiotic-resistant Gram-negative pathogens.

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More systematic tumor registration in Thailand nowadays uncovers new high-incidence areas that are confined to not only the northeastern part but also some provinces in northern Thailand. The results of our study demonstrate the feasibility of the combined photoacoustic and magneto-acoustic imaging that takes the advantages of each imaging techniques and provides high sensitivity, reliable contrast and good penetrating depth. T-cadherin is a binding protein for the high-molecular weight isoforms of adiponectin, an anti-inflammatory hormone that declines in obesity. Platelet-activating factor (PAF) is a potent signalling phospholipid that has been implicated in a number of biological activities. Sample preparation is important for isolating desired components from complex matrices and greatly influences their reliable and accurate analysis. Emergency room data such as triage time, time until seen by the orthopedic service, and total emergency room time was recorded. New developments in stent technology led to the first biodegradable magnesium stents. To determine the effect of the 11S/7S ratio, soymilk was fractionated by centrifugation after the addition of MgCl(2), and the distribution of lipids and proteins was studied. Classical conditioning features prominently in many etiological accounts of panic disorder. This review discusses the major advances that have increased our understanding of the mechanisms of renal water regulation in health and disease.

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The level of aggressivity of the different isolates was different for several host plants tested. Therefore, we propose that the regulation of hepcidin by the BMP pathway involves the formation of a diflucan breastfeeding side effects baby complex of liver-specific and response-specific transcription factors bound to the distal BMP-RE2 /bZIP/HNF4alpha/COUP region and to the proximal BMP-RE1/STAT region possibly by physical association of the 2 regions. When the membrane permeability of the liposomes was changed by altering the concentration of cholesterol in them, the initial rate of the eosin Y CL reaction was dependent on the membrane permeability of the liposomes. It was proposed that the effect was due to disruption of the perceptual memory by the verbalisation process as seen in face recognition. Pathophysiology of septic acute kidney injury: what do we really know?. Thus, fortification of infant formula with specific growth factors could soon become a preferred strategy to accelerate intestinal maturation in the premature neonate to prevent the development of NEC. Successful removal of an ileal gallstone by endoscopic ileocecal valvulotomy (with video).

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Studies were obtained from computerised searches of MEDLINE, EMBASE, The Cochrane Library and communication with experts in the field as well as insulin producing companies. From P15, rats in the HM group were continuously gavaged with the 1 ml/50 g body weight mixture, until two consecutive regular estrous cycles were established. From the remarkably large difference between the architecture and properties of the self-assembling materials based on the two similar peptides, it could be concluded that the self-assembly behaviors were delicate and could be dramatically altered by small modifying peptide structural features due to subtle changing the phenyl group position. Functional MRI of verbal self-monitoring in schizophrenia: performance and illness-specific effects. In order to maintain the QOL in lung cancer patients and also save on medical costs, chemotherapy should be performed on an outpatient basis as much as possible. Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts. In the current case, cell wall-positive tuberculous bacteria were cultured, confirming the presence of two separate diseases in the same patient. This letter discusses the difference between piezoelectric constitutive relations for the case of one-dimensional stress and the case of one-dimensional strain, and its implications in the modeling of Rosen piezoelectric transformers.

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