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Alpram (Alprazolam)

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Alpram is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpram is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpram may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alcalm, Aldep, Alfix, Alpracon, Alprasert, Alprazolam, Alpron, Alzolite, Alzonex, Alzopam, Ambulax, Anilam, Aryalam, Benzax, Deproz, Depsolam, Exiten, Flunix, Fluxin, Fultop, Kurelam, Notence, Poize, Prozam, Richpram, Serex, Somnirest, Stresnil, Tenschem, Tranisol, Xerodep, Zamitol, Zolin, Zopain

Similar Products:
Desyrel, Naprosyn, Coumadin, Catapres, Temovate, Duphaston

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpram. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpram XR dosage information

Side effects

The most common side effects associated with Alpram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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Deep wound infections after neuromuscular scoliosis surgery: a multicenter study of risk factors and treatment outcomes. As demonstrated here, all neuronal and macroglial cells of the retina appear to express high-affinity glutamate transporters. NRRL 3884, Actinoplanes missouriensis ATCC 23342 and Actinoplanes teichomyceticus ATCC 31121 deacylated MDL 63,246, dalbavancin and A40926. We used standardized protocols to estimate foraging raid rates and species composition of army ant communities in four Neotropical forests. These results suggest that the hydrotropic effect is related to alterations in the water structure induced by the hydrotrope molecules and to the presence of hydrotrope aggregates that furnish an appropriate niche for the surfactant amphiphile. Breast cancer screening: false positive rate is lower in older women. This suggests that luteinizing granulosa cells are refractory to mitogenic stimulation by EGFR ligands. Lastly, the device can be easily fabricated using a single-layered soft-lithography technology so that we believe it would provide a simple but robust means for many synthetic and systems biologists to simplify and speed up their investigations of the synthetic genetic circuits in bacterial cells. Gait improved by an average of 0.22 units/wk for those cows kept on pasture. We used a sequence containing full-length of COR domain and part of ROC and MAPKKK domain as bait.

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Muscular metastasis of a gastric carcinoma: the first sign of a recurrence of the disease. Other prospective studies with higher number of patients are needed to validate these results. The proportion with poor SRH increased with decreasing social class at baseline. We evaluated the long term clinical outcomes of femoral vascular closure devices following its deployment in coronary angiography and percutaneous coronary intervention (PCI) procedures. Here, we present the detailed mapping of the carrier density-dependent interatomic potential of bismuth approaching a solid-solid phase transition. In the 1970s the synthetic vitamin D analogue 1alpha-hydroxycholecalciferol was developed for intramuscular injection before a cow calved, but variable results encouraged other preventive strategies to be considered, including restricting the dietary intake of calcium, and manipulating the dietary cation-anion balance of cows before they calved. Abnormal chromatin clumping in leucocytes of Ph positive chronic myeloid leukemia cases - extending the morphological spectrum. The nanocrystals were characterized using X-ray diffraction (XRD), X-ray photoelectron spectrum (XPS), and transmission electron microscopy (TEM). Proliferative peritoneal and pleural cestodiasis in a cat caused by metacestodes of Mesocestoides sp.

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Using new methods to evaluate or diagnose lesions, further therapy and prevention for atherosclerosis will progress in future. In this study, 64 GmWRKY genes from soybean were identified, and were found to be differentially expressed under abiotic stresses. Prognosis was negatively related to large juxta-articular lesions. Here we describe how the advantage offered by off-line LC-MALDI-TOF/TOF mass spectrometry is exploited in a two-step workflow to focus the MSMS-acquisition on crosslinks mainly. A comparison of the therapeutic effects between related donor and unrelated donor allogeneic hematopoietic stem cell transplantation in treatment of leukemia. There is still a requirement for more ingenuity, persistence, and research if the goal of safer effective formation of anastomoses by less invasive means is to be realized. We investigated the influence of EN and PN on intestinal epithelial cells and peripheral blood (PBMC) and lamina propria mononuclear cells (LPMC), all of which are involved in the mucosal defense against bacterial translocation and systemic inflammation. The aim of this study was to investigate the presence, etiology and clinical significance of elevated troponin I in patients with acute upper or lower limb ischemia. Intensity-modulated radiotherapy as primary therapy for prostate cancer: report on acute toxicity after dose escalation with simultaneous integrated boost to intraprostatic lesion.

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CNTs-Modified Nb3O7F Hybrid Nanocrystal towards Faster Carrier Migration, Lower Bandgap and Higher Photocatalytic Activity. We investigated the frequency and imaging characteristics of STM lesions in patients presenting with myelitis as an initial manifestation of NMOSD. These HGF/SF-secreting hepatocytes can be used as a model system to test a feasibility of using genetically engineered hepatocyte cell line for hepatocyte transplantation in the rat. Unrepaired DNA lesions can block the progression of the replication fork, leading to genomic instability and cancer in higher-order eukaryotes. Molecular identification and in vitro response to antifungal drugs of clinical isolates of Exserohilum. The objective is to show that using the DICOM standard provides a good starting point for systems integration but is not a plug-and-play operation. There are, however, few empirical examples of its effectiveness and acceptability in practice. callosus showed that IgG, which shows no affinity to Protein A, has higher cross reactivity with rat IgG than with IgG from other rodents.

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To assess the strength of the glue and microbial contamination over 28 days from opening a vial of tissue adhesive in the accident and emergency setting, and to quantify cost savings of repeated use of the vials. The authors sought to assess the documentation of suicide risk assessments performed by psychiatry residents in a psychiatric emergency service (PES) and to identify differences in documentation between previously used paper charts and a new electronic medical record (EMR) system based on the Columbia Suicide Severity Rating Scale (C-SSRS)-risk assessment version. Patients were eligible if they received either fluoropyrimidine-based adjuvant chemotherapy or observation after R0 resection. By 3 days after grafting we found labeled cells with morphological characters of myocardiocytes in concordance with the identification of the expression of human genes for myosin light chain 2a (Mlc2a) and myosin heavy chain-beta (Mhc beta) in the chicken heart. Microarray experimental design can be treated as a multicriterion optimization problem.

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The GATA:FOG complex coordinates information transmitted by at least three different signal transduction pathways as a means to control stem-like cell fate choice. It underlines the numerous orientations available to the clinician and offers some indications for improving the treatment in these patients. The 32D/EpoR FE cells and mock transfected 32D cells have an immature, monoblastic morphology and do not express the primary granule protein myeloperoxidase. Gastrointestinal infection is a well-recognized trigger for functional bowel disorder. Over the last several years, the technique of endothelial keratoplasty has evolved to become an important alternative in the treatment of FCD. Effect of Psidium guajava leaf extract on alpha-glucosidase activity in small intestine of diabetic mouse.

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Our objectives were to review the retropharyngeal anatomy, define retropharyngeal adenitis and abscess, and determine if CT may guide the clinician in treatment planning for pediatric retropharyngeal infections. The BCTs that occurred more frequently in effective interventions, were: practical social support, behavioural practice, self-monitoring of behaviour and credible source for example a skilled clinician delivering the intervention. Although some of these premises are well grounded, others are questionable and limit the development of the specialty and its integration into mainstream psychology. Relationship of glycated haemoglobin and reported hypoglycaemia to cardiovascular outcomes in patients with type 2 diabetes and recent acute coronary syndrome events: The EXAMINE trial. The lactogenic hormone prolactin (PRL) regulates milk protein gene expression in mammary glands. A 27-year-old woman with systemic lupus erythematosus (SLE) was found to have acute acalculous cholecystitis. Rutin, an active flavonoid compound, is well known to possess potent antioxidant properties against oxidative stress insults through undefined mechanism(s).

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Changes in myocardial perfusion after catheter-based percutaneous laser revascularisation. However, control input frequency domain measures revealed that the pilots employed highly different control strategies in the pitch and yaw axes. To examine the relationship between hepatitis C virus (HCV) infection with menopause status and vasomotor symptoms among middle-aged, impoverished women. Here we suggest that public cord blood repositories are likely to contain CCR5 homozygous units that could be used as a therapy for HIV-infected individuals. This irreversible inactivation of mature parasites inside host cells makes plasmodial cysteine proteases attractive targets for antimalarials, as parasite-specific cysteine protease inhibitors may significantly augment multi-target drug cocktails. To investigate the incidence and mortality of colorectal cancer in China from 1998 to 2002, and to analyze its prevalence trend. Soft tissue sarcomas are uncommon tumors of mesenchimal cell origin. The purpose of this study was to identify socioeconomic, physician-related, and rural-urban factors that may influence the presence of a Medicare-certified hospice in three rural-urban areas. This lower energy state is rapidly deactivated by nonradiative self-quenching. Cells with suppressed expression of FOXD1 markedly reduced glioma cell migration.

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Follow-up by conventional radiologic and clinical criteria alone may not be enough, and patients may have problems, as in our series, that cannot be detected by conventional radiologic and clinical assessments. Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol. It is suggested that the Tyr substitution might initiate hydrogen bond formation with the amino group of CPC and facilitate deamination. In this review, we consider potential phytotherapeutic candidates among herbal- and fungal-derived medicinals for possible postnatal correction of the most predominant DIT-induced immune problems. This study indicated association between sexual risk behaviors and substance use among young men. Autosomal SNPs study of a population sample from Southern Portugal and from a sample of immigrants from Guinea-Bissau residing in Portugal. Bacterial translocation (BT) plays an important role in systemic complications in severe acute pancreatitis (SAP). The regression models yielded adjusted coefficients of determination (R(2)(adj)) of 0.735 and higher. Criteria used to assist decisions to admit a patient to the ICU and to select the initial ventilatory strategy are discussed. HG activated mitogen-activated protein kinase (MAPK) p42/p44 and protein kinase C (PKC) signals, whereas BK only activated MAPK.

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In this paper, we studied the cheating problem in VC and extended VC. Polysaccharides from Sargassum tenerrimum: structural features, chemical modification and anti-viral activity. The evidence gleaned from research demonstrates best practice methods rather than those we have traditionally used with little or no scientific basis. Our findings show that in vivo administration of lentiviral vector expressing VIP produces one of the most potent therapeutic effects described so far in any animal model of RA. Repetition factor substantiation of regular medical check-ups of children with face hemangiomas. Our data indicates that cultured chondrocytes undergo dedifferentiation during monolayer culture, although the gene expression level of transcription factors necessary for chondrogenesis remains unchanged. The economic burden of juvenile idiopathic arthritis-results from the German paediatric rheumatologic database. In this randomized clinical trial transurethral ethanol ablation of the prostate was safe and effective at 6-month followup. All groups received 11 separate intraperitoneal injections of PTZ (35 mg/kg) with two-day intervals.

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We believe that our approach provides a promising tool to assess the integrity of specific structural connections in patients with neuropsychiatric disorders. Of all missed lateral meniscal tears, most are unavoidable and related to confusion between what represents fraying and what represents a tear. The main difference is that in ISO 22000 systems like Good Manufacturing Practice and Good Hygiene Practice are prerequisites thus leading to lower number of CCPs. Attention-deficit/hyperactivity disorder (ADHD) often persists into adulthood, albeit with changes in clinical symptoms throughout the life span. The analysis used India-specific or international cost parameters to estimate the budget impact. However, dysregulated inflammation can cause secondary damage and could thus contribute to the pathophysiology of many diseases. PEMS is a promising technology whose use in the field remains to be demonstrated. A simulator to explore the role of haptic feedback in cataract surgery training.

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(4) The intestinal gene expression of cholesterol transporters NPC1L1 and ABCG5/G8 is unaltered, whereas the hepatic expression of ABCG5/G8 is diminished but strongly stimulated by thyroid hormone. Elevated defibrillation thresholds (DFTs) among recipients of a biventricular implantable cardioverter-defibrillator (ICD). Essential topics are the requirements for institutions performing the therapy. Bacterial populations were quantified in relation to the incidence of blister blight disease. We detail how recent findings have contributed to our knowledge regarding the pathogenesis and treatment of common obesity. Geographic targeting of nutrition programs differin resurfacing scar gel ingredients can substantially affect the severity of stunting in Honduras. These data suggest an important role for RALDH in modulating retinoic acid levels in different cell types during rat kidney development. Undertreatment with inhaled corticosteroids was the principal source of that inconsistency.

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Rats with liver fibrosis due to bile duct ligation or CCl4 were divided into three groups: sham, placebo and interferon alpha2a 100,000 UI/day. Recently P2RY12, a P2 purinergic receptor, was introduced as a specific marker for microglial cells under normal and pathologic conditions. We also compare a number of different compression techniques for achieving efficient delivery methods from an intelligent genomic search agent over the Internet. Although used in cutting-edge technology, it is surprising that a vital part in the construction of such displays, namely the alignment layer, relies essentially on a mechanical rubbing process, invented almost 100 years ago. We conclude that the multiple synapses formed by an SG EIN on a postsynaptic neuron increase synaptic excitation and provide basis for diverse forms of plasticity. Insect olfactory receptors are heteromeric ligand-gated ion channels. Samples were run in triplicate for 3 consecutive days, and results were reported as product-to-internal standard ratios and enzyme activity units (micromol/L/h).

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The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. For long, natural organic matter (NOM) composed mainly of humic substances (HS) were regarded as inert in the ecosystems with respect to their possible chemical interaction with exposed organisms. The effects of the NICE Technology Appraisal 121 (gliadel and temozolomide) on survival in high-grade glioma. The animal study results showed that the new gene vector HP gamma-CD-PEI-P significantly enhanced the anti-tumor effect on tumor-bearing nude mice as compared to PEI (25 kDa), HP gamma-CD-PEI, and other controls, indicating that this new polymeric gene vector is a potential candidate for cancer gene therapy. Data from albenza tab 200mg cost the Medical Expenditure Panel Survey (MEPS) for the years 1996-2005 were used. Plant protoplasts are embedded within surrounding cell walls and the cell wall-plasma membrane-cytoskeleton (WMC) structural continuum seems to be crucial for the proper functioning of plant cells. ERalpha is known to play a role in EMT, a process that may also involve TERT. Reliability of upper and lower extremity anthropometric measurements and the effect on tissue mass predictions. Chi-squared and Wilcoxon signed-rank tests were used for categorical and continuous variables.

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