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Alpraquil (Alprazolam)
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Alpraquil

Alpraquil is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpraquil, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpraquil is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Albiz, Alparazole, Alpkair, Alprasan, Alprawin, Alprazan, Altrex, Alzom, Alzonex, Alzopax, Anquil, Anxigo, Aryalam, Azolam, Azoslip, Calmef, Calmtec, Deproz, Diprex, Elzopam, Emcalm, Mentolift, Norex, Oclam, Pecalm, Pifzot, Prazolam, Propnix, Rivcam, Selam, Serex, Sinaday, Suzilam, Tagat, Tenolam, Tensfree, Tryzo, Unixl, Visram, Xerodep, Zodia, Zolent, Zoloid, Zolorest

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Alprostadil, Amoxil, Singulair, Artane, Avelox, Aceon, Reminyl, Bactrim, Ovral

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpraquil dosage information

Overdose

If you have been prescribed Alpraquil for medical reasons, the best way to avoid a Alpraquil overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpraquil consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpraquil XR dosage information

Side effects

The most common side effects associated with Alpraquil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Alpraquil if you are pregnant. It could harm the unborn baby.

Do not use this medication if you are allergic to Alpraquil or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before you take Alpraquil, tell your doctor if you have asthma or other breathing problems, glaucoma, kidney or liver disease, a history of alcoholism, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking Alpraquil. This medication can increase the effects of alcohol.

Alpraquil may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

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The Golgi-associated punctate structures originated from the ER exit site (ERES). This manuscript presents an application of the filter diagonalization method (FDM) in the analysis of this phenomenon. The present study does not provide evidence that occupational exposure to cis-DCP in the starch potato growing region causes adverse effects on the kidney or liver at 8 hour TWA exposure concentrations below 9.5 mg/m(3) (2 ppm). Despite significant functional improvement of hibernating myocardium as a result of PCI or pravastatin therapy, there were no changes in HED defect size or severity. To compare nosologist coding of underlying cause of death according to the death certificate with adjudicated cause of death for subjects aged 65 and older in the Cardiovascular Health Study (CHS). Surgical correction of cranial abnormalities, including craniosynostosis, requires knowledge of normal skull shape to appreciate dysmorphic variations. Correcting the C-7 plumb line value with minimal complications appeared to lead to better clinical results. The strong and stable lytic activity of this phage might enable its use as a therapeutic or biocontrol agent against S.

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Here, we have tested whether a similar approach could discriminate diabetic and non-diabetic patients. The difference between the predictive power of a predictive model with (enhanced model) and without (baseline model) a certain predictor is generally regarded as an indicator of the predictive value added by that predictor. All persons 15 through 24 years old by race whose cause of death was homicide (International Classification of Diseases, Ninth Revision codes E960-E969). Generation of an AMT database for a complex proteome requires combined efforts by many research groups and laboratories, but the chromatography data resulting from these efforts are tied to the particular experimental conditions and, in general, are not transferable from one platform to another. We report here that SsrA is needed for the correct high-level translation of RpoS. Refolding of the F protein from a metastable conformation to a highly stable postfusion form is critical for the promotion of fusion, although the mechanism is still not well understood. parasitica, Saprolegnia salmonis or just as unnamed Saprolegnia sp. However, WASH did regulate retromer-mediated retrograde CI-MPR trafficking, which required its association with endosomes, Arp2/3-directed F-actin regulation, and tubulin interaction.

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Interventions for bullying require a combination of scaffolding and social architecture to provide comprehensive supports and to change the social dynamics that enable bullying. Liver activity of selenium-dependent glutathione peroxidase 1 was measured as an indicator of selenium status. Penetrating femoropopliteal injury during modern warfare: experience of the Balad Vascular Registry. The long-term neuropsychological features of basal ganglia encephalitis. Discovery of novel indazole-linked triazoles as antifungal agents. Antimicrobial activity of selected South African medicinal plants. This ratio increases because roots are less sensitive than shoots to growth inhibition by low water potentials.

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Select NCEs were more active in vitro and showed greater efficacy than RFZ. Going forward, genome-scale in silico models promise to extend their application and analysis scope to become a trans-formative tool in biotechnology. The medical records and voiding cystourethrograms of the 624 consecutive patients with vesicoureteral reflux were retrospectively reviewed to identify siblings with vesicoureteral reflux. In contrast, its growth on a hyperosmotic medium was the slowest. Many advances in laparoscopic image display have led to an incremental improvement in performance. The Roma people originated in northern India and have been known in Europe for nearly a thousand years. However, isobutyl methylxanthine was more potent in the cyclooxygenase-1 deficient and heterozygous mice than in wild-type mice. Patients with severe extragenital LS benefit from pulsed high-dose corticosteroids combined with low-dose methotrexate therapy.

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Studies were included if cases were age-matched to controls or results were age-adjusted and if women with bilateral salpingo-oophorectomy were excluded. Herein, a case who developed psoriasis after Kawasaki disease is presented together with the related literature. Hormonal therapy (HT) is the current mainstay of systemic treatment for prostate specific antigen (PSA) only recurrence (PSAR), however, there is virtually no published literature comparing HT to observation in the clinical setting. When expressed in cultured cells, stefin B co-localizes with Abeta intracellular inclusions. Path analyses revealed significant direct paths from destructive marital conflict to negative parenting practices and lower scores on the self-control component of social skills. Retention prediction of low molecular weight anions in ion chromatography based on quantitative structure-retention relationships applied to the linear solvent strength model. As this theory continues to be applied, however, it has become increasingly clear that these human-IT microsystems are themselves imbedded within larger systemic contexts, and that both these contexts--as well as the interactions and change processes both between and among them--need to be clearly conceptualized and explored in greater detail. Diagnostic importance of bone marrow examination in non-hematological disorders.

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A critical reconsideration of the clinical effects and treatment recommendations for sodium channel blocking drug cardiotoxicity. A mobility shift detection method for DNA methylation analysis using phosphate affinity polyacrylamide gel electrophoresis. This study describes a new strategy for the identification of squamous carcinoma antigens tumor-associated antigens (TAA). We experimentally investigate sheared dense bidisperse granular materials as a function of the size ratio of the two species and find that the mixing rate at low confining pressure behaves as expected from percolation-based arguments. Who saves general nursing practice from inappropriate nursing assessments?. For 1:1 complexation systems between natural beta-CD, modified alpha-, beta-, and gamma-CD that bear one p-(dimethylamino)benzoyl (DMAB) moiety (DMAB-alpha-, beta-, and gamma-CDs) and guest molecules of widely varying chemical structures and properties, the binding constants of the complexes were successfully fitted using multiple linear regression (MLR) with hydrophobic descriptor log P (the partition coefficient between 1-octanol and water phases) and molecular connectivity indices. Axon sprouting in adult mouse spinal cord after motor cortex stroke.

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Taken together, our results suggest that NGF induces differentiation of PC12 cells via several signaling pathways, an important one of which is the MAPK pathway. The greater lubricity and resistance to scratching of oxidized zirconium femoral components are expected to result in less polyethylene wear than cobalt-chrome femoral components. The best studies of organelles to nucleus retrograde regulation exist in plant chloroplast-to-nuclear regulation and yeast mitochondria-to-nuclear regulation. Rolipram does not normalize very long-chain fatty acid levels in adrenoleukodystrophy protein-deficient fibroblasts and mice. Characteristic of HIV-infection epidemic process in Krasnodar region was done, which points to its evolutionary transformation during last years. Metabolomics methods for the synthetic biology of secondary metabolism. Although the use of GERBU adjuvant generally increased the specific immune response, some undesired side effects indicate a need to adjust dosage and/or improve the formulation. The phase deviation of -0.03155229 rad is generated when the spherical edema is considered. The efficacy of MDL is decreased in the silent period after SE, which can be partly accounted for by a reduction in GABA(A)-receptor density.

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All vaginal and urethral erosions were detected by physical examination and cystoscopy. The aggressiveness of the surgical intervention is patient- and disease-specific and requires frequent and open communication between all health care providers, the patient, and his or her family. This review contains a state-of-the-art discussion of (patho)physiological implications of GlyR RNA editing. Binary mixtures of 1-ethyl-3-methylimidazolium chloride with PEG of molecular weight 1500, 2000, or 3400 g mol(-1), or of 1-butyl-3-methylimidazolium chloride with PEG of molecular weight 2000 or 3400 g mol(-1), have been found to give rise to entirely liquid, stable biphasic systems over a significant temperature range (from 333.15 K to 413.15 K), while mixtures of 1-ethyl-3-methylimidazolium chloride with PEG-1000 and 1-butyl-3-methylimidazolium chloride with PEG-1000 and PEG-1500 are miscible. Effect of collagen digestion on the passive elastic properties of diaphragm muscle in rat. Also, works on PD pattern recognition in actual cable joint are less likely to be found in literature. Estimates of migration in vivo using bromodeoxyuridine labeling revealed that neuroblasts from KO mice show a decreased migration rate compared with those from WT mice. Pregnancy-specific beta-1-glycoprotein in first-trimester maternal serum is influenced by smoking. Results from this study suggested that in addition to initial efforts for enrollment, screening programs should emphasize increased rescreening especially for women with certain demographic and screening history characteristics. Effects of clinical communication interventions in hospitals: a systematic review of information and communication technology adoptions for improved communication between clinicians.

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This framework focused on conditions of seeking pediatric HIV care among community members and initiating pediatric HIV care by primary health care workers (PHCWs). Most disagreements occurred in eyes rated near the milder end of a category and/or resulted from small differences between the ophthalmoscopic and photographic definitions used in classifying severity. High RR and AR in the present epidemic indicate strong association between fogging and occurrence of symptoms. Acute lower respiratory infections (ALRI) are the major cause of morbidity and mortality in young children worldwide. The assembly and operation of the apparatus and the analysis of data are described.

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