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Alprax (Alprazolam)
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Alprax

Alprax is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprax, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprax is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Aleez, Allam, Alpracon, Alprasert, Alprastan, Alprogard, Alpronit, Alsert, Altok, Alwe, Alzex, Alzin, Alzoact, Alzoax, Alzot, Anxicalm, Anxiflu, Anxit, Anxitab, Anzal, Anzilum, Apsolam, Calmef, Dexolam, Endolam, Eurolam, Fludep, Flumusa, Fluxin, Luzarn, Pacyl, Prolam, Pronext, Pronil, Proprazolam, Resto, Rezolam, Samprex, Trika, Unixl, Xycalm, Zeecam, Zolark

Similar Products:
Imuran, Cytoxan, Crestor, Zithromax, Aricept, Theolair, Zofran, Aldactone, Zyloprim

Also known as: Alprazolam

Description

Alprax is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alprax is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alprax if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alprax or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alprax. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprax XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alprax XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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Identification of the Swedish Chlamydia trachomatis variant among patients attending a STI clinic in Oslo, Norway. Sphingosine kinase-1 mediates androgen-induced osteoblast cell growth. Current treatments include tricyclic antidepressants, anticonvulsants, and opioids, depending on the severity of the pain state. This article will focus on the diagnosis and treatment of PTSD and MDD consequent to burn trauma, as these are the major psychiatric outcomes, addressing the attendant psychosocial problems as threads in this post-trauma tapestry. This article provides an overview of meningitis and meningococcal septicaemia, which can have devastating effects. Primary corpus cavernous tumors are extremely rare and have possibly never been reported before. Interestingly, Rat-1 cells coexpressing cyclin E and PSM-RB could not complete DNA replication. Consenting patients were assigned randomly to remain hospitalized (hospital group) or be discharged to an ambulatory setting (ambulatory group). Various factors also influence skin exposure to UV light: the latitude, season, and time of the day.

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It is mandatory that ECG changes resulting from intensive physical training are distinguished from abnormalities which reflect a potential cardiac pathology. Drug Development, Trial Design, and Endpoints in Oncology: Adapting to Rapidly Changing Science. Cortical-evoked potentials were recorded with a magnetic stimulator placed over the lumbar paraspinal muscles with the patient in the prone position. With increase in the level of the alimentary motivation the generalization reaction began to be recorded to stimuli of different modality. Properties of phenol-removal aerobic granules during normal operation and shock loading. Anti-melanoma activity of hybrid peptide P18 and its mechanism of action.

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Prescribing patterns for combined pills and emergency contraception for Grampian general practitioners and Grampian Healthcare family planning service were also analysed. The intervention consisted of nurse-led cardiovascular risk management, including risk assessment, risk communication, a decision aid and adapted motivational interviewing. Cognitive tests included Trail Making Tests Parts A and B, Symbol Digit Substitution Test, and Paced Auditory Serial Addition Test. This review concludes that different psychosocial factors are associated with an enhanced or reduced cortisol awakening response. The tissue-specific regulation of the adenohypophyseal enzyme by estradiol and thyroid hormones suggests that it may serve an integrative function in modulating the response of adenohypophyseal target cells to TRH and thus pituitary hormone secretion. Standard parasternal long-axis and short-axis views permit the most accurate measurement of epicardial fat thickness overlying the right ventricle. Kidney biopsy should be performed in patients with TB and renal disease to ensure the diagnosis of renal involvement of active TB and established correct treatment (intensifying TB treatment or changing TB therapy in drug induced TIN). Analyses revealed that the CFS group reported higher levels than the control group on the Total Perfectionism score and Doubts about Actions and the Concern over Mistakes subscales. To understand better the transcriptional regulation of the hiNOS gene, the 8.3-kb hiNOS promoter was characterized.

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An attractive property of the optimization problem is that it is convex and, hence, has no local optima. It is caused by the mutation of the tumor suppressor gene NF1, which encodes neurofibromin. Akt-mediated survival of oligodendrocytes induced by neuregulins. Among other actions, regulation of cytokine production and secretion by immune cells, astrocytes and microglia (the brain immunocytes) has emerged as a main mechanism at the basis of adenosine effects in diseases characterized by a marked inflammatory component. Effect of intra-operative pressure support vs pressure controlled ventilation on oxygenation and lung function in moderately obese adults. The daily pattern of Fos synthesis by hypothalamic pro-opiomelanocortin neurons is unaffected by adrenalectomy in the rat. Mature leaves of the sweet pepper, Capsicum annuum, exhibited resistance against the American serpentine leafminer, Liriomyza trifolii (Burgess), Agromyzidae.

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These results indicate that patients who develop GBS respond differently to the ganglioside-like epitopes on Campylobacter than do non-GBS diarrhea patients. In the present study we examined the outcome of mixed-isolate infections in individual hosts, using a single clone of the waterflea Daphnia magna and three isolates of its semelparous endoparasite Pasteuria ramosa. Findings suggest that a stepped care treatment model for high-risk pregnant women with both MDD and PTSD could be integrated into public health systems in the United States. Triiodothyronine attenuates hepatic ischemia/reperfusion injury in a partial hepatectomy model through inhibition of proinflammatory cytokines, transcription factors, and adhesion molecules. We applied ApEn and SampEn to body temperature time series recorded from patients in critical state. Joint match probabilities for Y chromosomal and autosomal markers. Formation of nano-quasicrystalline decagonal phase in the Al70Cu10Co5Ni15 system by high energy ball milling. The patient demonstrated the typical clinical picture of macular corneal dystrophy. Interleukin-2 (IL-2) and its receptor (IL-2R) play a major role in cellular immunity.

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More than 200,000 people ask Novartis to drop its challenge on drug patent. The measurement of antibiotic timing in pneumonia has been shown to be associated with antibiotic misuse in emergency departments. No down-regulation of GFAP was observed when reactive astrocytes were similarly cultured with Schwann cells. Images in anesthesiology: reversible anterior spinal artery syndrome during celiac plexus block. government began to experiment with the use of the electron beam irradiation process for destroying such biological agents. Vitamin D and parathyroid hormone levels and bone mineral density in patients undergoing hematopoietic cell transplantation. These progenitor cells could further mature into pancreatic and hepatic cells with the supplement of exogenous inducing factors. Dosage analysis demonstrated that BID is located just distal to the CES region critical for the majority of malformations associated with the syndrome (CESCR), as previously defined by a single patient with an unusual supernumerary chromosome.

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Risk assessment of consumption of methylchavicol and tarragon: the genotoxic potential in vivo and in vitro. This system proves to be an efficient tool for separating targeted cells. The immediate-early 1 (IE1) and IE2 proteins encoded by the major immediate-early (MIE) transcription unit of cytomegaloviruses are thought to play key roles in the switch between latent- and lytic-cycle infection. However, when transcription of Tyrp-1, Mmcp-6, and PAI-1 was examined, no significant differences were detected between Mitf isoforms with exon 6a and those without exon 6a, except for Tyrp-1 transcription by Mitf-D/E isoform. To diagnose CTS on a background of polyneuropathy in mild cases in which sensory conduction is preserved, the ratio of sensory nerve conduction velocities of the palmar cutaneous nerve and the median nerve 1st digit-wrist segment may be a criterion. No final conclusion has yet been achieved on whether the area postrema (AP) is involved in the regulation of cardiovascular activity in the rats. Effect of solute hydrogen bonding capacity on osmotic stability of lysosomes. A servomotor system was utilized to impose bilateral hip oscillations at 0.5 Hz, while braces stabilized the joint position of both legs. CpG island methylator phenotype association with elevated serum alpha-fetoprotein level in hepatocellular carcinoma.

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Three regions of SV40 DNA were examined in each tissue: the non-coding transcriptional control region (TCR), the sequences encoding the host range domain (HRD) within the carboxy-terminus of T antigen (TAg), and a portion of the VP1 gene. During a patient information day, several mothers of ARM patients reported their concerns about previous miscarriages. Patients with detrusor underactivity with normal bladder sensation combined with a poor relaxation or hyperactive urethral sphincter were significantly more likely to recover normal detrusor function. Intracellular dye fills revealed axon arborization within neuropiles of ipsilateral pedal and cerebral ganglia, as well as in both buccal ganglia. The primary objective was to develop a mechanism-based PD model for the FPG-HbA1c relationship. However, few studies have examined immune responses in bats, and even fewer have evaluated these responses in an ecological context. It requires having an adequate spatial description of the relevant canonical molecular orbitals, which are obtained by expanding CMOs in terms of natural bond orbitals (NBOs). Central nervous system (CNS) involvement in systemic lupus erythematosus (SLE) is manifested by neurologic deficits and psychiatric disorders. a questionnaire was answered by 23 rock and roll musicians (46 ears) who were also evaluated by means of pure tone audiometry, immitance audiometry and transient/distortion product evoked otoacoustic emissions (OAET and OAEPD).

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The practical considerations inherent in this type of analysis are highlighted, as well as the use of this type of data to inform agency human resource strategies. The THI and tissue hemoglobin oxygen saturation (StO2) were measured using the InSpectra StO2 Tissue Oxygenation Monitor, Model 650, with a 15 mm optical sensor. We demonstrate that the toroidal dipole response in metamaterials can improve the quality factor of the resonance spectrum. The purpose of this study was to examine changes in the electromyographic (EMG) activity of the masseter muscle after radiofrequency therapy (RF). Influence of epidural analgesia on labor in mid and late termination of pregnancy: an observational study. Here, we report a novel, evolutionarily conserved, p53-mediated transcriptional mechanism that regulates p66shc expression and identify p53 as an important determinant of endothelium-dependent vasomotor function. Although limited information is available, upper body exercise and cycle ergometry of the lower extremities by functional electrical stimulation (FES) have been reported to have a salutary effect on these body composition and metabolic sequelae of paralysis. The medical records of patients with HCC undergoing liver transplantation in relation to recurrence and survival by comparing CM and CMB, were analyzed.

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Once identified, the citation frequencies of both groups were determined by using SCOPUS. Iodine-123-beta-methyl-p-iodophenyl-penta-decanoic acid myocardial scintigraphy showed decreased uptake in the mid-ventricle, corresponding to the mid-ventricular akinetic region. However, the peculiarities and difficulties inherent in these procedures require a specific training program combining theory and practice. It can bring a good postoperative appearance of the thumb and little influence on the hand function. Co-expression of peppermint geranyl diphosphate synthase small subunit enhances monoterpene production in transgenic tobacco plants. We have recently demonstrated down-regulation of a group of cell cycle related genes in acquired 5-FU resistant human cancer cell lines. Ionized and total magnesium concentration in patients with severe preeclampsia-eclampsia undergoing magnesium sulfate therapy. The aim of this study was to determine the actual cost per intensive care unit (ICU) day in Germany based on routine data from an electronic patient data management system as well as analysis of cost-driving factors.

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Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig. There was no difference in apoptotic neuronal cell death in the hippocampus among groups. Hormone therapy for the management of the menopause in Ecuador: perception, use and knowledge among middle-aged women. Adequate management of APT in patients with intracoronary stents who undergo potentially haemorrhagic invasive procedures depends mainly on the type of physician involved and their practice rather than on a carefully weighted assessment of ischemic/bleeding risk. The mechanism(s) which underline findings of severe adverse drug reactions (ADR) noted in more than a thousand published articles on CHIs, are still poorly understood.

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The effects of transcranial magnetic stimulation over the dorsolateral prefrontal cortex on suppression of habitual counting during random number generation. Fifty patients aged from 3 to 52 years (mean: 24 years) with established diagnoses of hyperimmunoglobulin E syndrome had MRI of the brain as part of an hyperimmunoglobulin E syndrome natural history protocol. Potential ability of hematoporphyrin to enhance an optical coherence tomographic image of gastric cancer in vivo in mice. Our results are consistent with the primarily negative results for that race/sex group. Here, we construct a gene module map to systematically relate transcriptional programs in embryonic stem cells (ESCs), adult tissue stem cells xanax drug action , and human cancers. The abundance of dynamic and disordered regions in proteins suggests that structural determinants alone may not be sufficient to describe function.

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Computer-assisted evaluation of nipple-areola complex sensibility in macromastia and following superolateral pedicle reduction mammaplasty: a statistical analysis. Numbers of myeloperoxidase-positive neutrophils, CD68-positive macrophages, and mononuclear cells were determined in tissue sections. We assessed the prognostic implications of GH on admission and during follow-up in critically ill adult patients admitted to a medical intensive care unit. Kiss1r-2 expression in the brain increased coinciding with the onset of puberty. Minimally invasive options such as percutaneous aspiration with or without ethanol sclerosis have had disappointing results.

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Aminoacyl-tRNAs were long thought to be involved solely in ribosome-dependent protein synthesis and essential primary metabolism processes, such as targeted protein degradation and peptidoglycan synthesis. This result hints at the activation of sympathetic beta-adrenergic receptors by AII counteracting the parasympathetic cardiac control. This preparation is an injectable solution containing 26.7 mg pentobarbitone and 133.3 mg pentobarbitone sodium per 1 ml. These enzymes of antioxidant defence system suppress oxidative stress and mitochondrial damage, whereas a decrease in anaerobic metabolism checks cancer growth. In women pregnant with twins, antenatal breastfeeding counseling did not significantly affect the breastfeeding rates. In the present report, GPR54 agonistic peptides having several nonhydrolyzable Gly-Leu dipeptide isosteres were designed and synthesized. This review aims to synthesize information regarding the fate and behaviour of PHCs in boreal forest soils in both ecological and sustainable management contexts.

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The authors undertook a study to explore the predisposing risk factors, frequency of occurrence, and clinical implications of kyphosis following laminectomy for cervical spondylotic myelopathy (CSM). Over several weeks, all neurologic and imaging deficits resolved. Borna disease virus--a possible etiological agent of human psychoneurological disorders?. intermedia LPS was enhanced by IFN-gamma independently of de novo protein synthesis, and was regulated, at least in part, at the transcriptional level. Upright MRI of glenohumeral dysplasia following obstetric brachial plexus injury. Validation of chromatographic methods: evaluation of detection and quantification limits in the determination of impurities in omeprazole.

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