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Alprowon (Alprazolam)
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Alprowon

Alprowon is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprowon, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprowon is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Actirax, Aldip, Alprogard, Alprotame, Alsert, Altalin, Altok, Alzotime, Anxicalm, Anxico, Anxigon, Anxilam, Anxorel, Anzal, Anzilum, Apsolam, Aryalam, Ateez, Axnil, Benzax, Cqlam, Enxolam, Finezol, Hiprazole, Jolistar, Kurelam, Luzarn, Maxorest, Normatine, Pralam, Pranol, Rezolam, Romipraz, Samitol, Sinzolam, Somnirest, Stresnil, Tenschem, Tensfree, Tenzorid, Texidep, Unixl, Zallpam, Zeprax, Zepro, Zodia, Zolent, Zolyde, Zopral

Similar Products:
Zanaflex, Cymbalta, Abilify, Dramamine, Danocrine, Albenza

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprowon. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprowon XR dosage information

Side effects

The most common side effects associated with Alprowon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid drinking alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Grapefruit may interact with alprazolam and lead to unwanted side effects. Avoid the use of grapefruit products.

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Semen cryopreservation for ex situ management of genetic diversity in chicken: creation of the French avian cryobank. The system is accurate and can be produced as a compact low-cost device that can make HRV monitoring more practical for home based health care and implantable devices. The chamfer algorithm is suitable for routine clinical use with minimal need for close inspection of image misalignment. Internal consistencies and interrater reliabilities of factors were stable across age groups and approximately 6.8 year retest reliabilities were high. The Impact of Somatostatin Receptor-Directed PET/CT on the Management of Patients with Neuroendocrine Tumor: A Systematic Review and Meta-Analysis. Cell proliferation, osteoblast differentiation, and osteo-related gene expression were enhanced on the NE60/10AO substrata compared with NE0, NE60/10, and NE0AO. We compared the average doses in the 26-week maintenance phase and the discomfort associated with the two routes of administration. However, the last two decades under the pressure of globalization Chinese medicine is turning gradually to evidence-based medicine, contributing in international biomedical research.

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After C60FAS administration, the TBARS content and H 2 O 2 level were decreased. Protein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases. A better understanding of this difference may lead to age-specific preventions and treatments for psychostimulant abuse. Achieving mutuality was especially a problem when smoking cessation advice was repeated at short intervals. Finally, we review the literature, with emphasis on the importance of excluding splenic vein thrombosis in patients with isolated gastric varices, and discuss certain features of the diagnosis and treatment of PPL. Mechanisms of the inhibitory effects of a phenoxazine compound, 2-amino-4,4 alpha-dihydro-4 alpha-7-dimethyl-3H-phenoxazine-3-one, on the contraction of the smooth muscle of the guinea pig taenia cecum. Patients who underwent surgical shunting were compared with those who had a TIPSS procedure following one-to-one propensity score matching. aureus (MRSA) has become an increasing problem in pediatric patients over the past decade.

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The main objective of this work was to use micronucleus induction in fish erythrocytes to study the risk to aquatic ecosystems due to the genotoxicity of Chlorotriazine Reactive Azo Red 120 textile dye. The authors identified CABIN1 among discriminating genes that may play a key role in the development of recurrence. We recruited 586 participants experiencing 651 illness episodes from a population of healthy adults enrolled in an influenza vaccine effectiveness trial. The cDNA is equivalent in size to the adult actin mRNA detected by Northern analysis. Lithocholic acid, deoxycholic acid, and ursodeoxycholic acid were significantly decreased in the stool of TG mice. Efficacy and safety of topical combinations of ipratropium and xylometazoline for the treatment of symptoms of runny nose and nasal congestion associated with acute upper respiratory tract infection. Do calcium antagonists contribute to gastro-oesophageal reflux disease and concomitant noncardiac chest pain?. The authors compared these indices for persons with and without social phobia and adjusted where indicated for the effects of major depression and relevant sociodemographic factors.

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Here, we provide a brief overview of the cough-related acid-sensitive sensory pathways and discuss the mechanisms of acid sensitivity. In this study, we investigated genome-wide differential gene expression in peripheral blood mononuclear cells (PBMC) from individuals with pre-malignant arsenic (As)-induced skin lesions before and after 6 months daily oral supplementation of 200 microg L-selenomethionine. In each region immunoperoxidase labeling for CB2-Rs was detected in neurons as well as in glial and endothelial cells. To estimate the effect of obesity prevention on annual and lifetime drug spending as well as other sector-specific expenditures, i.e. Obesity and dental caries in children aged 2-6 years in the United States: National Health and Nutrition Examination Survey 1999-2002. The kinetic values suggested that activity of enzyme was enhanced in the presence of dihydropyrimidine derivative. The porous nature and the high roughness of the resulting surfaces were confirmed by AFM imaging. Now we occupy the largest ecological and geographical range of any species, have larger biomass, and process more energy.

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Bile duct biopsy revealed malignancy, and thus bile duct resection and hepaticojejunostomy were performed. Different deletions resulted in different functional alleles for different breeding purposes. This article provides an overview of the gamut of biliary imaging techniques currently available to the clinician. Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice. The endogenous cannabinoid (or endocannabinoid) system (ECS) is part of a central neuromodulatory system thought to play a key role in the regulation of feeding behavior and energy balance. The effects of microwave irradiation on occluded solvents in illicitly produced cocaine hydrochloride. The approach is also extended to capture-recapture experiments with possible random removals.

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Given a fixed cost of pathological analysis, elimination of routine hernia sac examination may result in substantial annual savings. Both treatments induced cell death in CGC with higher cell-damaging effects at 12 DIV and 7 DIV neurons for St and LP, respectively. Evidence of construct similarity in Executive Functions and Fluid Reasoning abilities. DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2. The patient survived thanks to a large surgical debridement, and an early antifungal bitherapy by lipid formulation of amphotericin B and posaconazole. This observation supports the hypothesis that the Cdc6-2 protein functions as a helicase loader.

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To keep the technique safe, certain principles should be remembered and are detailed in this article. We report the first comparative study using two different needles for ablation of breast cancer. Alveolar macrophages in allergic asthma: an expression signature characterized by heat shock protein pathways. Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia). Changes in landscape composition influence the decline of a threatened woodland caribou population. Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness. Targeting the miR-200c/LIN28B axis in acquired EGFR-TKI resistance non-small cell lung cancer cells harboring EMT features. Hippocrates wrote about surgical treatment of varicose veins, Celsus and also Galien himself described varicose veins ligatures. We sought to analyse disagreements between reports from general radiologists and neuroradiologists in selected patients and to examine the impact of a four-point quality-improvement program in a DGH neuroimaging reporting service. The saturation time (ts) was 21 and 45 h for Cr(III) and Cr(VI), respectively, and a breakthrough time (tb) of 4 h for Cr(III) and 5 h for Cr(VI).

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The prevalence of GERD in our Iranian population was considerably higher than that reported from other Asian studies approaching western figures. Criteria for admission to specific specialist and non-specialist care environments should be standardised and the use of risk scores could be an important way forward. The tissue sections were subjected to matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) profiling and tissue imaging. Up to 100-fold increase in transfection efficiency of pDNA was seen for chitosan-IAA as compared to native chitosan, nearly matching that of PEI. A deletion mutant of p47(phox) proved that its C-terminal region was essential for the interaction. Commonly used measures include area under the curve (AUC), maximum plasma concentration (C(max)) and time to maximum concentration (T(max)).

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Motifs in two of the isolated genes suggest new links between cellular regulatory mechanisms (ubiquitination and phosphorylation) and mRNA splicing and chromosome structure/function. Functional roles of calcium-activated potassium channels on the mechanical activity of epicardial coronary arteries obtained from a canine model of diabetes were investigated. Illustrative examples further show that the proposed neural network can obtain a more accurate solution with a faster convergence rate than existing relevant methods. To investigate the association between hemoglobin scavenger receptor (CD163) expression levels on monocytic surfaces and coronary atherosclerotic severity in patients with coronary heart disease (CHD) as well as the roles of CD163 in inflammation and lipidperoxidation. The resulting transient EBIC was analyzed to form a lifetime map. To compare the 2-DE profiles for serum proteins of different pathological stages during hepatocarcinogenesis.

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Clinical commentators widely interpret crying as a sign of depressed mood. A group of 106 knee blocks were obtained from 56 individual donors (25 females and 31 males, aged 12-74, avg. She lived another 8 years, during which time she had a number of new dreams that correctly raised the likelihood of an active cancer despite normal physical exams and negative Pap smears. These findings support a metabolic block in oxidative metabolism resulting in lactic acidemia in dogs with lipid storage myopathy. Although psychologists have focused extensively upon negative qualities such as ethnocentrism and its roots, we suggest that the positive quality of identification with all humanity also merits extensive study. Like all MMPs, MMP-2 is secreted as an inactive zymogen (proMMP-2) and activated extracellularly by limited proteolytic cleavage. To investigate mortality trends in functionally dependent adults following traumatic brain injury (TBI).

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To form a basis toward defining the structure of what a winning organization culture looks like, 4 experts were asked 12 questions related to the development of an organizational culture. Cholesterol levels thus regulate fatty acid uptake by adipocytes via a pathway that does not involve altered cell surface localization of caveolin-1 or CD36. We tested whether genetic variants in CASP8, CASP10 and CFLAR, three genes important for death receptor-induced cell killing residing in tandem order on chromosome 2q33, are associated with cancer susceptibility. To investigate the role of bacterial DNA in development of an excessive inflammatory response and loss of gut barrier loss following systemic hypotension. Carotenoid depletion and ovarian dysfunction in common bully exposed to a New Zealand pulp mill effluent. The proportion of subjects achieving DLQI score 0/1 response at week 24, time to DLQI score 0/1 response, and sustained DLQI score 0/1 response up to week 52 were compared between secukinumab and etanercept. Problematic emotional processing has been implicated in the genesis and maintenance of anorexia nervosa (AN). HIF is primarily regulated by specific prolyl hydroxylase-domain enzymes (PHDs) that initiate its degradation via the von Hippel-Lindau tumour suppressor protein (VHL). The examinations were conducted in patients treated in two clinical departments of the University Hospital. The changes in various hemostatic parameters were examined within a period from 7 days before the onset of disseminated intravascular coagulation (DIC) in 114 patients (i.e.

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Influence of beta-cyclodextrin complexation on glipizide release from hydroxypropyl methylcellulose matrix tablets. The primary aim of this pilot study was to assess how well the combination of global positioning system (GPS) and accelerometer data predicted different activity modes. These are the first data showing the presence of three subfamilies of mariners in anophelines. A comprehensive bioactivation mechanism was proposed to account for the formation of the observed GSH adducts. However, it is still open to discussion why the growth promotion only applies to one or the other, but not simultaneously to both Monoraphidium species.

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Providing support while also helping patients and their families to face upcoming harsh realities is a delicate balancing act that needs to be further explored ventolin hfa drug classification . Torsion tests of cylindrical trabecular bone specimens from sheep lumbar vertebrae with and without bone marrow were conducted. At the end, we compare the calculated local and global population densities with other estimations from different parts of the world. Methamphetamine use is associated with childhood sexual abuse and HIV sexual risk behaviors among patrons of alcohol-serving venues in Cape Town, South Africa. As a result, the services have made renewed commitments to support the needs of these families of military personnel. Immunohistochemistry was performed for LGALS4 (Galectin 4), ACS5 (Acyl-CoA synthetase) and CLU (Clusterin) proteins: LGALS4 was highly up-regulated, particularly in the most differentiated tumors, while CLU was lost in all tumors.

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Increased prevalence of obesity and glucose intolerance in youth treated with second-generation antipsychotic medications. Anionic dendrimers based on melamine with disulfide bonds at the core were prepared to investigate the solubility of these architectures, the ability of these molecules to solubilize pyrene as a model drug, and the ability of these architectures to undergo thiol-disulfide exchange. We analyzed correlations between the estimated glomerular filtration rate (eGFR) and coronary atherosclerosis before and during statin therapy. The holding power of cancellous fixator pins was superior to that of cortical pins, irrespective of whether or not ovariectomy had been performed. Advances in molecular biology help to clarify pathogenesis, refine prognosis and detect potential targets for targeted therapy in a wide spectrum of CNS tumors. Factors associated with greater inequities include income, having a private health plan, and geographic location. Additive regression models, bootstrap and permutation techniques, were used as well as structural equation modeling and haplotype analysis. Spinal modulation of the muscle pressor reflex by nitric oxide and acetylcholine. Does early administration of bisphosphonate affect fracture healing in patients with intertrochanteric fractures?. EMS mutagenesis and selection for resistance to nitenpyram was performed on hybrids carrying a deficiency for this chromosomal region.

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Energy of K-momentum dark excitons in carbon nanotubes by optical spectroscopy. Assembly of a nucleus-like structure during viral replication in bacteria. The experimental variables were optimized to maximize the hybridization efficiency, detection sensitivity and speed up the assay time. A trapping mutant of PTP1B binds cortactin at the phosphorylation site Tyr(446), the regulation and function of which have not previously been characterized. This features may be useful for differentiating rheumatoid meningitis from subdural empyema, because the extent of the lesions on DWI matches the lesion on noroxin 400mg dosage FLAIR imaging in patients with subdural empyema.

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The large majority of respondents were in favour of an interdisciplinary training programme being developed on a European level together by the EANM and the ESR and the respective sections of the European Union of Medical Specialists. The influence of pore shapes on the band structures in phononic crystals with periodic distributed void pores. Posttraining administered 0.3 mg/kg 8-OH-DPAT did not affect the performance of both genotypes. Observational study of home visits in Slovene general practice: patient characteristics, practice characteristics and health care utilization. Sex is an important, often deteriorated, dimension of quality of life after cancer treatment. Laboratory and field evaluation of crystallized DOW 704 oil on the performance of the Well Impactor Ninety-Six fFine particulate matter fractionator. Cloning, localization and expression analysis of vacuolar sugar transporters in the CAM plant Ananas comosus (pineapple). Comparisons of species cranial growth trajectories between biomes revealed that allometric postdisplacement, as evidenced by decreased elevation of a constant ontogenetic slope, drives the convergent paedomorphic appearance of independent arid-dwelling forms. Considering the role of the superior colliculus and the spinal cord in human arm movements, this paper proposes simple approaches for the control of arm reaching. The issue of national diagnostic biases should be taken into account in comparative cross-cultural studies of almost any character.

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