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In contrast, the activity of liver cytosolic phosphoenolpyruvate carboxykinase and the level of its mRNA are not affected. The general notion of closed, desolvated active sites suggests the a priori hypothesis that steric hindrance prevents the nicotinamide ring from assuming a conformation that would lead to transfer of the pro-S hydrogen. Methods applied and results obtained in the activity of psychomotor development of creche children. The endothelial heparan sulfate-antithrombin III natural anticoagulant pathway in normal and transplanted human kidneys. Monoclonal antibodies produced after immunizing mice with cells of human gastrointestinal carcinomas define glycolipid antigens. Evidence is provided for an origin of the faster rhythm from the mascularis mucosae.
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Coronary angiography showed no significant stenosis and there were no segmental wall motion abnormalities on left ventriculography. The importance of operational definitions in design of a combat casualty information system. Visualization of beta-galactosidase by enzyme and immunohistochemistry in the olfactory bulb of transgenic mice carrying the LacZ transgene. However, in the presence of indomethacin, IL-1 down-regulates the receptor by destabilizing IL-1 receptor mRNA. Radiation protection and quality assurance in dental radiography. Increased eNOS protein was observed in the endothelium of permeable perilesional vessels and neovessels and in the endothelium of the hyperplastic pial vessels overlying the lesion site. In the axolotl, particularly, the anchoring fibrils or bundles of anchoring filaments, enmesh with the collagen fibres of the dermis. The findings in the present communication are consistent with studies using genetically modified PT in which the ADP-ribosylating capacity of the A-subunit was necessary for the effect of PT on lymphocytosis. Foveal cone spacing was measured in vivo using an objective technique: ocular speckle interferometry.
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We consider computational and experimental methods that can be used to examine the effects of specific structural modifications in constraining side chain groups of amino acid residues and their similarities in chi space to the natural amino acids to evaluate what sort of mimetics are likely to mimic normal amino acids. Reovirus sigma3 is a virion outer shell protein that also binds dsRNA and stimulates translation by blocking activation of the dsRNA-dependent protein kinase, PKR. Degradation of glial fibrillary acidic protein by a calcium dependent proteinase: an electroblot study. PCBs may be instrumental in the deterioration of sperm quantity and quality, a contaminated fish diet being the main source of exposure. The specific red cell adherence test was negative before radiotherapy in 9 patients, 4 of whom (44 per cent) had positive tests after treatment. m-Hydroxybenzylhydrazine, a dopa decarboxylase inhibitor, had no inhibitory action on the deposition of the transparent capsule material.
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One factor of importance for delayed tissue repair and arteriosclerotic disease in diabetic patients might be a disordered endothelial cell-dependent fibrinolytic system. Chronic disseminated intravascular coagulation due to abdominal true aneurysm in two cases--effect of anti-platelet and anti-fibrinolytic therapy. A review of eight such studies indicates an increasing tendency to minimize INH hepatotoxicity and to disregard the declining tuberculosis morbidity and mortality in countries in which INH prophylaxis has not been widely adopted. Screening for adolescent smoking among primary care physicians in California. Walls of these cells consist firstly of regions containing the primary pit fields and composed of microfibrils oriented predominantly transversely. With the synthesis of new biostable polyurethanes, the integration of advancing technology, and better knowledge of the functional and biomechanical design requirements necessary to increase the long-term durability of the polyurethane heart valve, novel clinical solutions are now in sight. Two separate 1, 25-(OH) 2-D3 preparations, biologically active in other systems, were ineffective under a wide variety of experimental conditions. Pulmonary rehabilitation programmes have been shown to improve both exercise tolerance and health status in patients with chronic obstructive pulmonary disease (COPD).
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In the QOL questionnaires, no differences were noted between the two treatments. It was stated that a decrease in the ATP levels reduced or ceased the translational motion of spermatozoa, therefore the investigations of adenosine phosphates in the spermatozoa were found to be mandatory. Based on one case of rotator cuff tear and intrabursal fluid outlined by two adjacent fat stripes we reviewed 20 shoulder MR examinations to define the normal and abnormal appearance of the peribursal fat. Having analysed the case histories of 121 patients with unilateral aseptic necrosis of the femoral head the authors revealed early roentgenologic symptoms of aseptic necrosis in the other hip which was normal on admission in 19 patients with absence of the clinical signs of the disease. Project MICAS--medical information, communication and archive system: PACS implementation at the University of Rochester Medical Center. Enolase isoenzymes in uveal melanomas--a possible parameter of malignancy. Role of transcutaneous pacing in the setting of a failing permanent pacemaker. Estrogen treatment and estrogen suppression: metabolic effects in adolescence.
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The plasma retinol concentrations ranged between 29.19-141.37 micrograms/dl (mean 63.01 micrograms/dl). In contrast to mature females, shortly before ovulation, levels of inhibin alpha-subunit mRNA were low in small antral follicles (approximately 350 microns). Moreover, thyroid hormones have been shown to be effective as adjuncts for traditional antidepressant medications in treatment-resistant patients. Normative data regarding public perceptions of and motivations for MEP are nonexistent. Mechanism of inhibition of cholesterol uptake by the arterial wall. Effect of selected organopolysiloxanes on male rat and rabbit reproductive organs. A single oral dose of amoxycillin is recommended for standard prophylaxis, and ampicillin in combination with an aminoglycoside for parenteral use. Epidermal atrophy, alterations of the skin adnexa and changes in the dermal tissue are characterizing the so called corticosteroid-skin. A continuous exposure to proteinase started at the time of cell plating caused a temporary block of DNA synthesis that was followed by an accelerated growth rate 48 h later (approximately 1.5-fold). The GIF subunit may also be eluted from the modified cellulose using certain glycoproteins and sugars.
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The rats were divided into four groups: control, hypoxia/reoxy-genation, heat shock pretreated, dexamethasone pretreated. The adaptations of activity that occur when animals of the two strains are starved, fed a carbohydrate-free diet or made streptozotocin-diabetic are similar in the two strains. Antigen receptor proximal signaling in splenic B-2 cell subsets. These results suggest that the proposed PCP model in mice will provide a tool to test beneficial effects of atypical antipsychotics on social dysfunction in schizophrenia, and contribute to our understanding of the mechanisms by which clozapine improves SB deficit. The endogenous synthesis of Ia antigens by these cell lines was confirmed by biosynthetic labeling with radiolabeled amino acid precursors and indirect immunoprecipitation on sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis. Comparison with plasma cortisol evolution in four cases of human protracted whole-body irradiation. Results showed that neocarzinostatin traversed the cell membrane into cytosol and nuclei, and it appeared to have a preferential cytotoxicity for the cancer cell. Changes in serum folic acid and vitamin B12 levels in liver cirrhosis and its clinical significance.
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The effect of local administration of recombinant interleukin-2 (rIL-2) on metastatic gastric tumor: report of an autopsy case. Studies have been carried out at the plant physiology and plant biochemistry level in an attempt to measure the emission of isoprenoids by plants. Determination of trioses in tungstate supernatants of rat liver homogenates. More experience is needed to establish the incidence of this complication. The earliest CT changes are noted by 12 to 24 hours and include generalized ventricular enlargement and a focal region of decreased absorption in the opercula-basal ganglia region.
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The formation of the Delta(5) double bond in PGE(1) causes no change in its vasodilator activity, whereas the saturation of the Delta(13) double bond of PGE(1) slightly reduces its activity.5. Effects of ICI 170,809 as single oral doses (3, 7, 15 and 30 mg) or placebo were studied on the duration of antagonism for the ex vivo platelet aggregatory response to 5-HT and to the pupillary light constrictor response in eight healthy male volunteers. The use of retroauricular, supraclavicular or inner arm skin for grafting whenever possible is advised. Hypertension and arteriosclerosis in executive and nonexecutive personnel. Relationship between the mode of care for preschool children and the number of acute diseases in the long-term follow-up of a group of Prague children from birth to 15 years of age. Immunoblot experiments using a rat brain homogenate revealed a specific band at a position corresponding to a molecular weight of 600 kD. Review of aphakic glaucoma after surgery for congenital cataract.