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Ambiz (Zolpidem)

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Ambiz is a sedative, also called a hypnotic. Ambiz affects chemicals in the brain that may be unbalanced in people with sleep problems insomnia). Ambiz is used to treat insomnia. The immediate-release tablet is used to help you fall asleep when you first go to bed. The extended-release form, Ambien CR, which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep.

Other names for this medication:
Ambiz, Ambulax, Azold, Dactive, Getrest, Insom, Inzofresh, Isodem, Kayzole, Lipidem, Lopitas, Lypin, Nidra, Nitrest, Olpid, Restem, Sobrium, Stilnoct, Syzol, Zanlop, Zedem, Zleep, Zodem, Zolax, Zolcent, Zoldem, Zolep, Zolfresh, Zolip, Zolit, Zolnex, Zolojet, Zolpel, Zolpiapt, Zolpid, Zolpidem, Zolpimist, Zolpirest, Zolpistar, Zolpitrac, Zolsoma, Zoltar, Zolway, Zomnia, Zopid

Similar Products:
Crestor, Moduretic, Rulide, Combivent, Intagra, Luvox, Singulair, Adalat

Also known as: Zolpidem


Ambiz (zolpidem tartrate) is a gamma-aminobutyric acid (GABA) A agonist of the imidazopyridine class and is available in 5 mg and 10 mg strength tablets for oral administration.

Zolpidem tartrate is a white to off-white crystalline powder that is sparingly soluble in water, alcohol, and propylene glycol. It has a molecular weight of 764.88.

Each Ambiz tablet includes the following inactive ingredients: hydroxypropyl methylcellulose, lactose, magnesium stearate, micro-crystalline cellulose, polyethylene glycol, sodium starch glycolate, and titanium dioxide. The 5 mg tablet also contains FD&C Red No. 40, iron oxide colorant, and polysorbate 80.


Take Ambiz exactly as prescribed by your doctor. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed.

The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Zolpidem may be habit-forming. Misuse can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Do not share this medication with another person, even if they have the same symptoms you have. The recommended doses of Ambiz are not the same in men and women, and this drug is not approved for use in children. Misuse of this medication can result in dangerous side effects.

Never take this medicine if you do not have a full 7 to 8 hours to sleep before being active again.

Ambiz is for short-term use only. Tell your doctor if your insomnia symptoms do not improve, or if they get worse after using this medication for 7 to 10 nights in a row. Do not take this medicine for longer than 4 or 5 weeks without your doctor's advice.

Do not stop using Ambiz suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using the medicine.

Insomnia symptoms may also return after you stop taking Ambiz, and may be even worse than before. Call your doctor if you still have worsened insomnia for the first few nights after you stop taking this medicine.

Do not crush, chew, or break an Ambiz CR tablet. Swallow the pill whole.

Store at room temperature away from moisture and heat. Do not freeze.

Detailed Ambiz dosage information


In postmarketing experience of overdose with Ambiz tartrate alone, or in combination with CNS-depressant agents, impairment of consciousness ranging from somnolence to coma, cardiovascular and/or respiratory compromise, and fatal outcomes have been reported.

General symptomatic and supportive measures should be used along with immediate gastric lavage where appropriate. Intravenous fluids should be administered as needed. Ambiz's sedative hypnotic effect was shown to be reduced by flumazenil and therefore may be useful; however, flumazenil administration may contribute to the appearance of neurological symptoms (convulsions). As in all cases of drug overdose, respiration, pulse, blood pressure, and other appropriate signs should be monitored and general supportive measures employed. Hypotension and CNS depression should be monitored and treated by appropriate medical intervention. Sedating drugs should be withheld following Ambiz overdosage, even if excitation occurs. The value of dialysis in the treatment of overdosage has not been determined, although hemodialysis studies in patients with renal failure receiving therapeutic doses have demonstrated that Ambiz is not dialyzable.

As with the management of all overdosage, the possibility of multiple drug ingestion should be considered. The physician may wish to consider contacting a poison control center for up-to-date information on the management of hypnotic drug product overdosage.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Ambiz CR dosage information

Side effects

The most common side effects associated with Ambiz are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Conditioned reflex characteristics of the auditory analyzer in turtles. Metabolic clearance rate and blood production rate of testosterone and dihydrotestosterone in normal subjects, during pregnancy, and in hyperthyroidism. 34 of 36 rotavirus immune electron microscopy (IEM) positive samples showed a positive SA test, whereas none of 41 IEM negative specimens agglutinated the staphylococcal reagent. Systemic antibiotics for treatment of the conjunctivitis-otitis media syndrome. Effects of ingestion of thermally oxidized edible oils on plasma lipids, lipoproteins and postheparin lipolytic activity of rats. Inadvertent intracranial placement of nasogastric tubes may occur during intubation of patients with severe maxillofacial trauma and basal skull fractures. Upon exposure to lithotripter-generated shock waves eukaryotic cells display a temporary increase in membrane permeability. The internal remodeling theory of Cowin and Hegedus is employed to show the existence of final inhomogeneity following stress concentration. Second lethal yoelli infection: in the mice of shamoperation of 2nd yoelii infection the parasitized erytrocyte was lower than that of shamoperated group, but the higher level antiplasmodium antibody and uptake rates of 51Cr-RBC of unit weight splenic tissue.

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The reaction products of thiamine pyrophosphatase and nicotinamide adenine dinucleotide phosphatase were located within the mature-surface and intermediate saccules of Golgi body respectively. The expected tHcy-lowering effect of improved renal function may have masked a tHcy-elevating effect due to reduced proteinuria leading to no net change in tHcy during treatment. This enabled an entire binding curve to be obtained in a single experiment. Although currently the resolution of the replica technique cannot be surpassed, the method greatly facilitates the processing of brittle, rapidly frozen samples because no replica cleaning is necessary. Insulin increased protein kinase activity, and this was completely inhibited by the PKC pseudosubstrate inhibitor peptide (PKC19-36). Liquid-phase microextraction and capillary electrophoresis of citalopram, an antidepressant drug. They guarantee the basic supply of antidotes in all part of Switzerland. Stress reactions of various judging groups to the child dental patient.

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Tyrosine phosphorylation and activity of phospholipase C-gamma 2 and Syk protein tyrosine kinase were significantly higher in MZ cells than in FO cells after mIgM engagement, providing a likely explanation for our previous findings. A mechanistic study on the enhancement of corneal penetration of phenylephrine by flurbiprofen in the rabbit. Some remarks about its epidemiology and scarcity in the white race era done. This study is a retrospective analysis of the cytologic results of all patients examined provincially in 1988 and a review of the clinical records of patients diagnosed with invasive cancer and those who died of disease. Identification of a hemadsorbing agent discovered in uninfected mouse L cell cultures and also the same cultures chronically infected with Sindbis virus. Epidemiology of tumors of the testis in Indre-et-Loire from 1978 to 1987. The infiltration in the former strain contained fibroblast-like cells and epithelioid cells early on in the infection. Major risk factors for the disease are advanced AIDS, chronic sinusitis or otitis, neutropenia, use of corticosteroids and prolonged use of broad spectrum antibiotics. Effect of feeding on the excretion of nitrogen in fattening pigs.

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Focusing on the distal end of several femoral artery bypass junctions, a validated finite volume code has been used to compute the transient three-dimensional velocity vector fields and its first and second surface derivatives in order to test the idea. Interleukin-1-beta and tumor necrosis factor-alpha increase peripheral-type benzodiazepine binding sites in cultured polygonal astrocytes. Supplementary ratings assessed mouth dryness and stomach fullness. The examination included determination of visual acuity, perimetry, ultrasound echography, fluorescence angiography of the eye fundus. As originally publised in 1989: Right thoracotomy, femorofemoral bypass, and deep hypothermia for re-replacement of the mitral valve. Surgical intervention, however, often leads to additional endocrine disorders. Affected animals had high hemagglutinating antibody titers to Sarcocystis antigen. During a 31-month period in 1979-1981, nine patients at a renal transplant center in Tennessee developed invasive infections with Aspergillus species. Although a total gastrectomy with Roux-en-Y diversion can reduce the incidence of acid reflux, neutral enteroesophageal reflux may be observed during a radioactive isotope study.

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Two patients with ovarian carcinoma developed acute erythroleukemia following prolonged chemotherapy with an alkylating agent. An EDAP LT-01 lithotripter was used to treat 100 patients with functional gallbladders containing one to three radiolucent stones not larger than 20 mm in diameter, and 9 patients with bile duct stones. The Listeria in the lesions are primarily found inside macrophages, but a few are extracellular amid cellular debris. The diagnosis (congenital chylothorax) was confirmed at autopsy. Role of xanthine oxidase and xanthine dehydrogenase systems in thymocyte apoptosis, induced by papaverine. Twenty-nine patients with systemic lupus erythematosus were treated with a new synthetic unsaturated prednisolone derivative, triamcinolone, for as long as 11 months. Functional equivalency and diversity of cis-acting elements among yeast replication origins.

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Using specific polyclonal antisera, immunohistochemistry was used to determine the patterns of synthesis and distribution of collagenase (MMP-1), stromelysin (MMP-3), gelatinase A (MMP-2) and gelatinase B (MMP-9) and of the tissue inhibitor of metalloproteinases-1 (TIMP-1) within developing human osteophytic bone. The head of a 16 week old human fetus with anencephaly was serially sectioned and the craniofacial bones, cartilages and major blood vessels were traced and reconstructed by 3D-computer technology. It appears that as Tris is titrated to a neutral species the energetically unfavourable juxtaposition of its positive charge with that of paraquat is reduced. Adjustment of the interface detector (location 71) to the absolute number of mononuclear cells in the peripheral blood: no improvement of the collection efficiency of the Fenwal CS3000 plus during progenitor cell harvests. Diminished binding of thyroid-stimulating hormone in a transplantable rat thyroid tumor as a possible cause of hormone unresponsiveness. Microsomal cytochrome P-450 catalyzed an efficient 25-hydroxylation of vitamin D3, but no 25-hydroxylation of vitamin D2 could be detected. We conducted an intensive epidemiologic and laboratory investigation of one of these outbreaks to determine clinical characteristics, risk factors for transmission and infection, and methods of control and prevention.

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Postpartum ovarian artery rupture with retroperitoneal hemorrhage. Efferent connections of cortical, area 8 (frontal eye field) in Macaca fascicularis. Kinetic analysis of the interaction between the monoclonal antibody A33 and its colonic epithelial antigen by the use of an optical biosensor. During the full-blown delirium, the electroencephalogram had demonstrated diffuse slowing while lumbar puncture, brain scan, E.M.I. Group II pups also exhibited a significant increase in phosphomonoester, indicating developmental differences in phospholipid metabolism.

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The staging of rectal tumors with endorectal study technics: the demonstration of a possible source of error. Waiting time in special pediatric hospitals and balneologic institutions. Whether these experimental results are universally true require the clinical trials in future. This suggested the existence of enhanced sensitivity and/or responsiveness of the B cells of obese animals to the parasympathetic system. Spontaneous intracerebral hematoma in a adolescent with factor XIII deficiency. Histologic examinations were also performed to try to obtain morphological confirmation o results from the exposed clinical methods. Factors which modulate the function of these regulatory proteins are discussed, and a schematic of heme activation and repression is presented.

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They consisted of necrotic lung tissue invaded by fungus with separation from the surrounding lung so that the sequestrum had the appearance of a fungus ball. Digitized data points used as descriptive features provided good classification success and required minimal computation. The angle in the anterior slice is larger than that in the posterior slice. Elevated platelet-derived growth factor production by aortic grafts implanted on a long-term basis in a canine model. The consumption of NADH was shown to exceed two times the consumption of FMN in the anaerobic reaction and the rate constant in the aerobic reaction was found to be about 4 times of that of the anaerobic reaction. These studies provide evidence that GHB exerts cytotoxicity specifically for cells that by their content of tyrosinase convert the phenol to the quinone.

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It contains alpha-amanitin-resistant RNA polymerase I activity and rDNA as its major (or sole) DNA component. The reproductive potentials of strains Yersinia pseudotuberculosis serovars I, II, III, IV and V cultivated at different temperatures on media containing rhamnose, raffinose and sodium succinate were examined comparatively. In superficial areas denuded of synovial lining cells, high amounts of fibronectin were found incorporated in fibrin. Several lines of evidence suggest that 1,25-dihydroxyvitamin D3 (1,25D3) may be important in chemoprevention of human cancer. A fast sensitive method for the isolation and quantitation of biliary bile pigments by reverse-phase high-performance liquid chromatography has been developed. Following analysis, embryos identified as unaffected are replaced in the patient. The use of bone cement balls in chains loaded with omnicef pill size gentamycin (gentamycin-PMMA-ketten) as part of a two-stage exchange operation has proven to be a good method of treatment for infected arthroplasty. An ordered sequential mechanism with protein substrate binding first is unique to p38 compared to cyclic AMP-dependent protein kinase (cAPK) and most tyrosine kinases and helps to explain the interaction between enzyme, substrates, and inhibitors. Five patients underwent occipitocervical fixation for the lesion of the upper cervical spine, and one patient underwent separate occipitocervical fixation and cervicothoracic fixation. While similar in structure, the two genes differ in their expression pattern and may have different roles in central nervous system development and function.

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Accumulation of deleterious genes in a cage population of Drosophila melanogaster. The host cell reacts against the parasites by forming a thick border of mitochondria and distinct endoplasmic reticulum. elavil dosage chart Thus dose normalization at hot spot and the isocenter should be discouraged unless the total dose to the breast is modified. Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts): report of 2 cases. Ultrastructural changes during cholestasis induced by chlorpromazine in the isolated perfused rat liver.

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Practical experience in the detection and investigation of acute occupational diseases and poisoning. Dimethylglycine at a dose of 25 and 35 mg kg(-1) significantly reduced ulcer number, ulcer size and ulcer index in pyloric-ligation-, ibuprofen- and stress-induced ulcers. Which should be the role of bone ultrasonography in the therapeutic follow-up of postmenopausal osteoporosis?. Immunological localization and tissue distribution of alkyldihydroxyacetonephosphate synthase and deficiency of the enzyme in peroxisomal disorders. SMP-I and -II do not bind to unphosphorylated and thiophosphorylated is generic lexapro expensive myosin. An FSH and prolactin-secreting pituitary tumor: pituitary dynamics and testicular histology. Production and characterization of monoclonal antibodies to group-specific antigenic determinant of group A streptococcal polysaccharides. We report the case of a 25-year-old woman who presented with significant haemoptysis, dyspnoea, reduced transfer factor and normal clinical examination. Eighty-nine (89) patients presenting the ocular signs and symptoms of allergic conjunctivitis were enrolled and randomly distributed among the three treatment groups.

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