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catarrhalis was found significantly more often than in the scheduled cultures. All 14 anti-HCV patients were tested for HCV RNA and HCV genotype. The formation and recovery of two-break chromosome rearrangements from irradiated spermatozoa of Drosophila melanogaster. The results showed that endurance training leads to increased activities of oxidative enzymes in the skeletal muscle. Both groups of protein depleted Vervets developed a minor decrease of serum and intestinal immunoglobulins, as well as marked impairment of exocrine pancreatic function. Normoglycemia in rats allotransplanted with islets of Langerhans was studied. Type 2 diabetic patients new to insulin therapy demonstrated lower risk of nocturnal hypoglycaemia with insulin lispro. On account of firm and stable fixation, the patient was able to start drilling the limb in 1 to 7 days after surgery, and regained full extension and flexion of knee joint in 6.8 weeks on average. Thus, the enzyme activity changes in narrow submicromolar ranges and reaches maximal stimulation, but it does not extend to the levels above those stimulated by calcium alone.
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Immunosuppression and plasmapheresis in chronic progressive multiple sclerosis. A new polyether antibiotic CP-82,009 (C49H84O17) was isolated by solvent extraction from the fermentation broth of Actinomadura sp. Both total and unbound (free) tryptophan were higher in cord vein plasma than in the maternal circulation, the concentration gradient being approximately 1 : 2. Molecular characterization of two beta-lactamase-specifying plasmids isolated from Neisseria gonorrhoeae. It has been suggested that the development of hyperuricemia in CHD patients is dut to the mechanism of disturbances in binding of uric acid to transport blood proteins. A possible common mechanism of action of antidepressant treatments: reduction in the sensitivity of the noradrenergic cyclic AMP gererating system in the rat limbic forebrain.
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It was found that there was very little difference in the response of the two age groups to cortisol treatment. The double-tagged protein significantly enhances the efficiency of Western blot and immunoprecipitation detection as compared with the single-tagged protein. Despite this, no evidence of protein synthesis was obtained, based on measurements of total IgA content before and after organ culture or inhibition of IgA synthesis by cycloheximide. The authors suggest that individual nurses have a role in the solution. Imaging of small airways disease, with emphasis on high resolution computed tomography. Survey data were collected on the incidence of epileptic seizures in 997 Belgian tervuerens. Intriguing structure-activity relations underlie the potent inhibition of HIV protease by norstatine-based peptides. Spasticity, decerebrate rigidity and the clasp-knife phenomenon: an experimental study in the cat. However, it is not known whether, independent of effects on plasma concentration, the extent to which quinidine prolongs the QT interval also is modulated by changes in endogenous sympathetic activity. Molecular evidence for shifts in polysaccharide composition associated with adaptation of soybean Bradyrhizobium strains to the Brazilian Cerrado soils.
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Agrobacterium tumefaciens C58 mutates to tetracycline resistance at high frequency, complicating the use of many broad-host-range cloning and binary vectors that code for resistance to this antibiotic as the selection marker. Clinical studies on peripheral hemodynamics in arterial hypertension. It is presented a rare case of cholesterol pericarditis associated to sub-clinical hypothyroidism, showing the presence of cholesterol, as crystals in the pericardial effusion and, we think for the first time in this pathology, in vesicles of pinocytosis, in the pericardial biopsy. Heparin and warfarin are antithrombotic agents effective against venous thrombosis as well as pulmonic and systemic emboli. Developmental changes in the basal and evoked heart rate in neonatal rats. Together with a number of phase II trials, phase I trials utilizing escalating doses of carboplatin and paclitaxel with growth factor or growth factor and blood stem-cell support have shown that substantial increases in dose intensity can be achieved. The transition of cadherin expression in osteoblast differentiation from mesenchymal cells: consistent expression of cadherin-11 in osteoblast lineage. To expedite clinical implementation of 103Pd, an atlas of dose distributions for 103Pd implants has been produced for various seed configurations, seed spacings, and target volumes. Near-infrared spectroscopy is a useful method of continuously monitoring myocardial oxygenation and ischemia during warm heart surgery. The present experiments demonstrate that sublethal concentrations of propionic acid stimulated aflatoxin production considerably in submerged shaken culture and solid substrate culture of Aspergillus flavus.
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A protein, isolated and purified from the unheated culture filtrate of Mycobacterium bovis BCG (substrain Tokyo 172) and designated MPB70, elicited a delayed skin reaction in guinea pigs sensitized with viable cells of BCG but not in those sensitized with heat-killed cells. The heart shock stimulates the increase in the RNase activity, since no rapid increase occurs during the free running division cycle but a rapid increase occurs after an additional heat shock given at different times during the cell cycle. When Chinese Hamster lung fibroblasts (CHE36-6) or SV40 transformed 3T3 (SV3T3) cells are incubated with colchicine (1 muM) for one hour at 37 degrees C, they round up into spheres with short spikes. Astrocytic neuroglial cells, identified by morphology and staining properties, predominate. Lung cancer is frequently encountered by the radiologist, whether the lung cancer is detected on a chest radiograph obtained in a symptomatic patient, or is an incidental finding. The dose of TRH used caused a significant increase in the plasma level of TSH which indicated a normal pituitary responsiveness to TRH.
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Reversible diminished insulin requirement during acute renal failure. Cross sections of tissue samples were imaged by a linear scan of the samples while a focused ultrasonic transducer detected the time-resolved thermoacoustic signals. An adaptive Reichardt detector model of motion adaptation in insects and mammals. Smoking prohibition in the workplace and smoking cessation in the Federal Republic of Germany. Viability evaluations conducted 2 h after injury with phase contrast microscopy showed no evidence of slowed deterioration.
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Infusion of insulin (10,000 muu./kg.min) caused a large increase in glucose uptake accompanied by a reduction in fatty acid uptake.5. The jail-associated outbreak predates an extensive ongoing outbreak of louse-borne typhus in central eastern Africa after civil war and in refugee camps in Rwanda, Burundi (1), and Zaire. Immunohistochemical observation of actin filaments in epithelial cells encircling the taste pore cavity of rat fungiform papillae. Steroids extracted from as little as 0.05 ml of plasma are incubated with 3H-dexamethasone and cytosol receptors from cultured rat hepatome cells. The obtained results indicate that atrial dilatation is arrhythmogenic and may lead to the development of atrial tachycardia. The effect of domperidone (2 mg kg-1) on the pharmacokinetics of a single oral dose of theophylline (25 mg kg-1) was studied in the rat.
Guinea pig lymph node lymphocytes were reacted with two mitogenic lectins (LcL-A or PHA) and two nonmitogenic lectins (AbL or WGA)m and the levels of cAMP and cGMP were determined during 30 min of culture. Boys exposed to medroxyprogesterone acetate in 1 study did not differ significantly from normal controls with respect to a variety of sex-dimorphic behaviors. Suppression of active but not passive autoimmune encephalomyelitis by dual cyclo-oxygenase and 5-lipoxygenase inhibition. However, total BAL protein content was not attenuated significantly by the three treatments at either 6 or 24 h postexposure. Comparative classification for fractures of the distal end of the radius. The influence of low doses of harringtonine (Ht) on differentiation of blood cells from acute myeloblastic (AML) and lymphoblastic leukemia (ALL) patients diagnosed according to FAB classification was tested. Participants were questioned about their sociodemographic characteristics and about their knowledge of pregnancy and childbirth and psychomotor development in the infant, using 28 question sets (118 items). Remote observations on minute volume following total and partial pneumonectomy in humans. We evaluated short-term treatment of tinea corporis with butenafine hydrochloride, a new benzylamine with in vitro fungicidal activity. Effects of prolonged hydrochlorothiazide administration on neurogenic tone in the hind limb vasculature.
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The TL-related leaks had a significantly higher surgical repair rate than RS-related leaks, an additional factor to consider when choosing an approach. Livers were removed for study from rats which were subjected to various systemic infusions or physiological perturbations. To elucidate the conditions influencing hla expression, the determinant was fused to lacZ, the reporter gene coding for beta-galactosidase. Additional cardioplegic perfusion was achieved by perfusing the vein graft anastomosed to the left anterior descending coronary artery below the obstruction, or other vein grafts anastomosed to the circumflex artery or the right coronary artery (or its branches if dominant), during total aortic clamping. Among them, R5 and R6, but not R3, inhibited thrombin-induced aggregation of washed platelets and the concomitant secretion of serotonin. Autoregulation of directly measured blood flows in the superficial and deep venous drainage areas of the cat kidney.
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The skin lesions improved gradually after the discontinuation of heparin application. Generalization, indicated by myeloid metaplasia, can occur at every stage, even in so-called hypercellular phases of IMF. Prognosis of glomerulonephritis in children based on personal cases. The incidence of acute inflammatory lesions was also not significantly higher in treated animals than in controls. Case detection rates that were lower than expected offer tentative support for the hypothesis that the initial florid episodes of schizophrenia may be modified when they are detected early and when effective therapeutic strategies are applied with minimal delays. TKA during which a pneumatic tourniquet was applied or not applied to control blood loss.
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In contrast, triamcinolone acetonide suppressed the firing induced by prostaglandin suggesting that steroids may be effective in the treatment of root symptoms. This method is considered useful because it permitted us to understand quantitatively the positional relationship and the balance of eyes, nose, and mouth in the face and to make comparisons with typical subjects. Comparison of the clinical and immunological indices in children with diabetes mellitus and obesity. This suggests that the intrinsic protein kinase activity of membrane preparations may be due to the presence of a specific protein kinase. A comparison of clinical course with blood group antigen testing by specific red cell adherence and immunoperoxidase in ureteral and renal pelvic tumors. 25 young women, 13 of whom on oral contraception (OC), were observed to study the effects of exercise and of OC on the blood fibrinolytic and renin systems. The incidence of muscle pains and changes in serum concentrations of potassium, calcium and creatine kinase following suxamethonium were investigated after no pretreatment or pretreatment with intravenous tubocurarine 0.05 mg.kg-1, intravenous chlorpromazine 0.1 mg.kg-1, alphatocopherol (vitamin E) 600 mg in three divided doses orally, aspirin 600 mg orally or intravenous calcium chloride 5 mg.kg-1 in groups of 20 patients each. PI 3-kinase is present in bovine rod outer segments and its activity appears to be greater in light-adapted retinas. First, a short historical review will be made because it gives a perspective for the understanding both of progress made and prevailing misconceptions.
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Hemoglobin synthesis as measured by the incorporation of 59Fe into cyclohexanone extractable heme was augmented in culture by hemin. By the end of the 6 month treatment-study period, the following results were obtained: 1. The level of free adenine in thymocytes and spleen T-lymphocytes during tumour growth showed a 2-4-fold increase in comparison with normal values. The results suggest that the antioxidant activity of 2-ME delayed the accumulation of free radical damage in spleen lymphocytes, which resulted in a delay in the decline of immune function and was associated with the decreased tumor incidence and increased life span. To determine how early and reliably ischemic brain infarcts can be detected on CT scanning, we report two cases of an early CT finding of acute ischemic infarcts where CT examination was obtained within the first 3 hours of onset of neurological symptoms. Although stroke volume increases through use of the Frank-Starling mechanism in many patients with severe systolic LV dysfunction, some patients with this disorder may not increase stroke volume during exercise due to diastolic LV dysfunction or pericardial constraint. Interleukin 1 alpha increases serum leptin concentrations in humans. Surgical treatment is indicated when the deformity interferes with sexual intercourse or is accompanied by severe urethral strictures. Cytokine production during infection with Hymenolepis diminuta in BALB/c mice. Paclitaxel was administered by one hour infusion at a dose of 175 mg/m2 for the first cycle, and was escalated up to 255 mg/m2 over successive cycles if tolerated.