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Amitrol (Amitriptyline)

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Amitrol is sometimes used off-label, meaning not FDA approved, for certain conditions. Some providers will use this medication to treat nerve pain. This can be helpful for people who have diabetes or fibromyalgia and haven't felt relief with other medications.

Other names for this medication:
Abamax, Amiclozor, Amitone, Amitrip, Amiwel, Amoten, Amrea, Amsha, Amtran, Axtrip, Emotrip, Eptanol, Gentrip, Latilin, Mitrip, Nextrip, Psycomer, Raitrip, Ristryl, Ronet, Triplent, Trixide, Tryline, Tryptomec, Typteez

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Also known as: Amitriptyline


Amitrol target is the treatment of depression. Amitrol is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amitrol is Amitriptyline. Amitrol is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amitrol are Amitrol, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amitrol if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amitrol if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amitrol is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amitrol is not approved for use by anyone younger than 12 years old.

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We report the crystal structures of the copper and nickel complexes of RNase A. The 14 anthropometric measurements could be used as references for the designs of furniture for preschool children. Direct assays revealed that this difference was because the thyroid adenylate cyclase response to TSH was less in the iodine-enriched animals, phosphodiesterase activity being no different in the two groups. Myocardial dysfunction and altered ventricular excitability could be related in uraemic HD patients to alterations of calcium transport, as found in the erythrocyte model. This study compares the potencies of the porcine gastrin-releasing peptide (pGRP) and bombesin, in causing elevations of canine plasma gastroenteropancreatic (GEP) levels. Suspensions of HeLa cells and human platelets, added to a medium of cultured human umbilical-vein endothelial cells, were stimulated by the addition of thrombin. No significant differences were found in estimated arterial CO2 tensions (PaCO2) or estimated alveolar ventilation (VA) between the cycling trials for either the runners or the cyclists. The characterization of Chilean and Bolivian Trypanosoma cruzi stocks from Triatoma infestans by isoelectrofocusing. Patients with tetanus usually require intensive care with dose monitoring and extensive supportive care. Effect of viskenit on the efficiency of the left ventricle in patients with post-infarction angina pectoris - echocardiographic study.

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Stimulation of cutaneous and muscle afferents induces several cardiovascular adjustments such as hypertension, tachycardia, and muscle vasodilation. Deoxyoligonucleotides containing d-G cluster were synthesized to elucidate exact structures and properties of the parallel-four stranded complexes of oligo(dG). Excretion of purine derivatives by Holstein cows abomasally infused with incremental amounts of purines. We tested the requirement for wild-type p53 in the response of tumor cells to treatment with paclitaxel (trade name Taxol), an antineoplastic agent that stabilizes cellular microtubules. During this time new vaccines were added to the immunisation schedule, enabling comparison of reporting rates.

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Immunocytochemical demonstration of retinol-binding protein in the lysosomes of the proximal tubules of the human kidney. Increases in manic symptoms after life events involving goal attainment. Leukotriene B4-activated human endothelial cells promote transendothelial neutrophil migration. Effect of temperature on the separation of the esters of fatty acids by open tubular gas chromatography. Pronase first solubilized the linkers and C tubules of the triplets, then attacked the protein portion of the axosome, a localized portion of the ciliary axoneme adjacent to the distal end of the basal body, the rim fiber, and newly described lumen spiral complex. Occlusions in the system of cerebral veins were observed in 39 pregnant females (1 per 5640 labor cases).

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Obviously, severe anemia has adverse effects on the mother and the fetus. While concentration of copper, zinc and lead decrease with increasing size, no such relationship is observed for cadmium. All injuries with neural involvement are by definition unstable injuries grade 3. This review considers these issues in the context of a critical evaluation of the pertinent literature. The aim of this study was to evaluate the role of RAR beta expression in the propagation of a malignant phenotype in human pancreatic carcinoma cells.

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Turnover is especially critical in nursing homes: continuity of care and personal relationships between care-givers and residents are important determinants of quality of care. Oxytropium bromide elevated the response threshold and decreased bronchial reactivity to vagal stimuli. In two experiments, mesiocclusion and distocclusion were produced in monkeys by means of cemented inclined planes. Production of nitric oxide by nitric oxide synthase (NOS) has been implicated in numerous physiologic and pathophysiologic processes including mutagenesis. The pigment mutants with an impaired light-harvesting chlorophyll a/b-protein complex possess photochemically active reaction centers of photosystems and are capable of phototrophic growth. Mineral corticism syndrome: classification, etiology and pathogenesis.

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An attempt is being made to produce two-helix bundles that are soluble in apolar media, without the use of a rigid template. Grafting of 2-methacryloyloxyethyl phosphorylcholine on to a cellulose membrane surface. Smoking alcohol consumption and dental health behavior among 25-44-year-old Danes. The detection of circulating immune complexes containing C1q and IgG using a new rapid serum ELISA test system. Headache secondary to an extradural cyst after lumbar disk surgery. The authors describe the surgical training opportunities provided by the ODTS since 1986. 123I single photon emission computed tomography (SPECT) brain images demonstrated decreased uptake in the same regions. One case died before any surgical intervention could be performed and one patient did not require surgery. The titers of infectious virus internalized into piD-10 and piD-11 cells were the same as those in DBT cells.

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While other factors may be operating in this situation, it is possible that the light treatment caused the stabilization of the free-running rhythms, advancement to a normal phase and entrainment to the 24-hr day. We report here that interleukin 1 from either source stimulates hyaluronate synthesis by synovial membrane cells. With time, this fullness decreased, leaving little evidence of the graft and an overall improvement in the aesthetic result. No glucagon immunoreactive neurons were detected in the retina of the rat, rabbit, cat, pig or cow. Immunohistochemically, CD-1a positive cells (immature thymocytes) decreased in cases with thymic involution. Of late, the use of gossypol and progestagen/androgen combinations have demonstrated the promise that an effective male chemical contraceptive might be developed during this decade. In the latter group, the effect of indomethacin was considerably reduced, whereas the difference was smaller with aspirin. Journal keeping as an educational strategy in teaching psychiatric nursing. Comparative characteristics of anesthetics of the xylocaine series. The first trip: life crisis and the first experience with hallucinogenic drugs.

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Reaction with EDC plus (3H)glycine resulted in the incorporation of glycine into sigma. haemolyticus, strain Dick I, for the evaluation of these properties of thioglycol medium have been established. Intranuclear inclusion bodies were found occasionally also in the reticular and parenchymal cells of the bone marrow, lymphoid organs, liver, adrenals, and pancreas. Study 2 addressed the effect of co-administration of cortisol with L-arginine on plasma L-arginine concentrations. I conclude with a quotation from Sauerbruch (15), who had successfully removed an insulinoma from a 7-year-old girl: If in medicine we can speak about causally induced disorders, then it is justified here. If this were not so, the ATP supply of a cell would be rapidly depleted.

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Because of the primary importance of the deltoid muscle to shoulder function, injury to the axillary nerve must be carefully avoided during reconstructive shoulder procedures. The over-all response rate to therapeutic thio-tepa was 56 per cent, with toxicity observed in 26 per cent of the cases. In contrast with tolbutamide, TA-078 hardly affected fasting blood glucose levels in rats and dogs and only weakly reduced fasting blood glucose levels in mice. A critical review of low-level prenatal lead exposure in the human: 2. From its distribution it appeared to be derived from fibroblasts and/or tumour cells. However, allotype suppression in this rabbit is maintained by endogenous anti-allotype antibody. RNA isolated from cultured human umbilical vein and normal human dermal microvascular endothelial cells was analyzed by reverse-transcriptase polymerase chain reaction (RT-PCR). To compare immunofluorescent and immunoperoxidase staining of Rickettsia rickettsii in skin biopsies of patients suspected of having Rocky Mountain spotted fever (RMSF). However the presynaptic inhibition of Ia spindle afferents simultaneously induced by the vibration works in reverse on the same rank order of motoneurones of the soleus spinal pool, thereby limiting the polysynaptic recruitment of units in the tonic vibration reflex while depressing the autogenic phasic proprioceptive reflexes. Pretreatment of the blastospores with detergents, salts, urea, glycosidases, lipase, or pepsin did not affect adherence, but treatment with reducing agents or five proteolytic enzymes did render C.

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Concentrations in serum as low as 0.5 mg of gentamicin per liter could be accurately determined. Effect of gentamycin on the melanosomes in the stria vascularis of the pigmented guinea pig: an ultrastructural study. Liver disorder owing to estrogen therapy in prostatic cancer, examined histopathologically in six autopsy cases. They elicited bradycardia and lowered the arterial blood pressure, but they do not demonstrate analgesic and diuretic activities. Tibialis posterior tendon dysfunction: a primary or secondary problem?. The visual information surrounding the target was always provided prior to movement onset, but during the execution of the movement on only half of the trials. Diabetes mellitus secondary to idiopathic chronic calcifying pancreatitis in an adolescent woman.

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A 55-year-old man with invasive thymoma (Masaokas classification, Stage IVa) underwent thymo-thymectomy, partial resection of left upper lobe, resection of phrenic nerve and partial resection of parietal pleura on March 14, 1989. Intravascular complement activation in rats following thermal injury or vascular infusion of cobra venom factor results in acute lung injury as determined morphologically and measured by increases in lung vascular permeability. Effects of methylglyoxal bis(guanylhydrazone) on tumour and skin responses to hyperthermia in mice. It is concluded that GTH-production in pituitaries of immature female rainbow trout can be directly influenced by gonadal steroids and by a hypophysiotropic substance. The calculated probability of identity was 2.26 x 10(-11) giving an average probability of identity of 1 in 44 billion. Based on the derived temporal features, a set of relational descriptors can be defined to describe the spatio-temporal relations between the multichannel phasic activities. We studied 120 consecutive autopsy cases including 100 cases of stroke (50-80 years) and 20 cases of cancer as controls (50-80 years).

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Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides. Randomised trial of three approaches to sore throat: a 10 day prescription of antibiotics, no antibiotics, or a delayed prescription if the sore throat had not glucophage drug interactions started to settle after three days. Superoxide and nitric oxide had no effect by themselves on the rate of glutamate uptake by astrocytes. Cur I and Cur III also exhibit in vitro cytotoxicity against human chronic myeloid leukemia, which is dose dependent. We describe a 25-year-old male who developed, in the course of an acute exacerbation of his multiple sclerosis, cluster headache-like attacks which responded to oxygen therapy. Effects of dietary ethanol on ascorbic acid and lipid metabolism, and liver drug-metabolizing enzymes in rats. Some aspects of the histo-pathological diagnosis of early cancer of the cervix. Lectures on infectious psychoses found during a visit to Czechoslovakia. The antibody basis of immunity in chickens to the nematode, Ascaridia galli.

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A structure-activity relationship study revealed that the structural combination of a thio group at the 21-position and an ester group at the 17-position contributed to vasoconstrictive activity. Three groups of DBA/2J mice were continuously exposed for 3, 6 or 9 days to a milled diet containing phenobarbital. IGF-I and bFGF differentially influence atrial natriuretic factor and alpha-smooth muscle actin expression in cultured atrial compared to ventricular adult rat cardiomyocytes. Changes in concentration of hydrogen ions in plasma and cerebrospinal fluid during hemodialysis. Expression of prostaglandin endoperoxide synthase-1 in a baculovirus system.

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Expiratory characteristics were examined using the ratio of expiratory volume in 1 sec to the expiratory volume in 0.5 sec and the ratio of expiratory volume in 1 sec to peak expiratory flow rate. Deuterium isotope effect in in vivo bioactivation of chloroform to phosgene. Treatment strategies for neurodegenerative diseases based on trophic factors and cell transplantation techniques. Patterns of cardiovascular dysfunction in chronic obstructive lung disease. Prophylactic administration of phytomenadione to the infant rather than to the parturient is recommended. From the soil in the area around the Syowa Station, the East Ongul Island, the Antarctica, a total of 193 strains of clostridia were isolated and identified.

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Except for myeloid hyperplasia induced by tumor bearing, hemopoietic repopulation in locally irradiated femoral bone marrow (1000 rad LI) by endogenous cells was greatly diminished for at least 3 weeks. In these cases and in a further 7 German patients the disease was sporadic. Hemoglobin increased from a value of 8.4 gm/dl in 1989 to 10.7 gm/dl in 1996. Surgical excision of the primary site was not performed in patients who had complete clinical response. During embryonic and postnatal development OCAM was strongly expressed by M/T zebeta dose cells in the caudal zone of the AOB where OCAM-negative vomeronasal axons terminated. The secondary lobule in the adult human lung, with special reference to its appearance in bronchograms. Fenoterol (Berotec) was administered by inhalation, using a Bennett nebulizer, to symptom-free asthmatic children aged 6-13 years. Understanding the relative influence of neighborhood, family, and youth on adolescent drug use.

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aegypti in residential areas with sparce vegetation and thus is very limited in its distribution within the city. flagyl dosage c diff Lipoteichoic acid is the major cell wall component responsible for surface hydrophobicity of group A streptococci. In overnight fasted rhesus monkeys, synchronous, regular oscillations occurred in the plasma concentrations of glucose, insulin, and glucagon. Antibody to hepatitis E virus in HIV-infected individuals and AIDS patients. Abortion during the 1st trimester by means of polyclinical vacuum aspiration without anesthesia. At least 4 of these patients experienced a recurrence when re-exposed to growth hormone. We investigated the performance of the B3LYP density functional in combination with ab initio effective core potentials (ECPs) that are derived from either Hartree-Fock or Dirac-Fock calculations. The demonstration of ferrihemochrome intermediates in heinz body formation following the reduction of oxyhemoglobin A by acetylphenylhydrazone. The relation of immune response to pathogenesis, vaccination and epidemiology in virus induced leukaemia. The deep S wave in leads V1, V2, and V3 in right ventricular hypertrophy.

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Use of new osteotropic isotopes in osteoarticular diseases, with special reference to phlogistic arthropathies. In 1987 a 40-year-old man with ESRD treated with hemodialysis had the AIDS-related complex. The value of cinephlebography in detecting incompetent venous valves in the post-phlebitic state. Serological studies (elevated CF and precipitin antibody titer) suggested the diagnosis of a CMV infection. Fluid and electrolyte resuscitation of the thermally injured patient. Natural history of intraductal papillary mucinous neoplasms (IPMN): current evidence and implications for management. Effect of oral magnesium supplementation on blood pressure, platelet aggregation and calcium handling in deoxycorticosterone acetate-induced hypertension in rats. An increase in gingival sulcular fluid filtration is a common clinical sign of early gingivitis. The aneurysm was discovered incidentally in 6 patients, and as a result of cardiac symptoms in an other 14.

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Glass ionomere cements did not show any significant differences from enamel. The movement profile analysis can be useful in the specified analysis of movements-influencing drugs. Toxicity and metabolism of trichloroethylene in rat hepatocytes. Activity of soluble and bound hexokinase in transplantable hepatomas of different degrees of malignancy, and in normal and regenerating mouse livers. The complementary structure of the superficial and deep surfaces of the cells of the stratum corneum of the hard palate in the rat. Potential halogenated industrial carcinogenic and mutagenic chemicals. The results are seen to be functionally dependent upon the pattern of underlying variability assumed in the model and upon the quadrature rule used to estimate the integral. The seasonal index of mean birth weight showed a peak in winter to early spring and a bottom in summer with statistical significance. Needle length and injection technique for efficient intramuscular vaccine delivery in infants and children evaluated through an ultrasonographic determination of subcutaneous and muscle layer thickness.

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The findings must be correlated in relation to the primary disease. These factors define a steep gradient of risk, suggesting that many injury deaths could be prevented. Consequences on the design of dose response experiments are investigated. Electrono-optical analysis of dental enamel with incipient pathological changes. Reversible increase in QT dispersion during carbon monoxide poisoning. Properties of horse liver alcohol dehydrogenase modified by the affinity label 3-chloroacetylpyridine-adenine dinucleotide. 6 of 12 patients xanax pill blue 8707 with double vision had mechanical disorders of eye movement. These results suggest that red cells with Jolly bodies, Pappenheimer bodies or basophilic stippling do not influence the automatic counting of reticulocytes. Fatty acid composition of cerebrosides and phospholipids in brains of undernourished rats.

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The acute response of liver of channel catfish and rat to polychlorinated biphenyl was compared on a structural and functional basis. Riboflavin-sensitized photooxidation of indoleacetic acid and related compounds. Injuries to other body regions are difficult to prevent and other measures such as legal and administrative means, should be fully exploited in accident prevention. At least eight inherited neurodegenerative diseases are known to be caused by expanded CAG repeats encoding polyglutamine (polyQ) stretches. The crude extract and saponins of Indian pseudoginseng and saponins of Korean ginseng have been studied using a battery of biological tests in rats and mice. Clinical experiences with carteolol in patients with essential hypertension. The accuracy of the name of the authors, title of the article, volume, initial and last page and year of publication were evaluated, accordingly with the NEFROLOGIA normative. Present status of the use of growth hormone in short children with bone diseases (diseases of the skeleton). The radioactive microsphere method was used to quantitate preoperative and postoperative blood flows in macaque monkeys when three different surgical approaches for anterior maxillary osteotomy were performed.

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Comparison of the results obtained by four different detection techniques. The effect of hGH on PB-mediated induction of P-450(6)beta-1(6 beta-3) and P-450(6)beta-4 mRNAs was also examined. The application of matched filtering to contrast material dose reduction in digital subtraction angiography. The other 12 pilots in the control group only did routine physical exercises, but the training time was the same in these two groups. Prediction of bone strength from cancellous structure of the distal radius: can we improve on DXA?. Cellular recovery from anaerobiosis was observed soon after transfer of the cells into fresh aerobic culture medium but occurred slowly if the cells were only resupplied with air. We conducted this prospective longitudinal multicenter study to evaluate the health-related quality of life (HRQL) of patients with oral carcinoma at diagnosis, and after 1 and 5 years in relation to tumour location and treatment modality.

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