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Amixide (Amitriptyline)

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Amixide is a medicine used for treating pain. You can take it: to treat nerve pain (neuralgia) and back pain. to help prevent migraine attacks. The FDA withdrew the drug in 2000 following reports that it increased the risk of heart problems. Doctors may still prescribe the drug, but only in rare cases when it is necessary.

Other names for this medication:
Abamax, Amiclozor, Amidez, Amiline, Amitar, Amitin, Amitrac, Amitrip, Amitriptyline, Amitrol, Amitryptyline, Amitwix, Amizep, Amoten, Amsha, Amtipax, Amtran, Amypres, Anitryp, Aptric, Eliwel, Emotrip, Eptanol, Estiline, Gentrip, Kamitrin, Libral, Raitrip, Relidep, Ronet, Teedep, Typlin

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Also known as: Amitriptyline


Amixide target is the treatment of depression. Amixide is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amixide is Amitriptyline. Amixide is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amixide are Amixide, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amixide dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amixide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amixide if you are allergic to Amixide components. Do not take Amixide if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amixide if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amixide if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amixide you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amixide if you are going to have a surgery. It can be dangerous to stop Amixide taking suddenly.

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Two hundred and eighty-three patients were admitted to a randomized, prospective and double-blind trial of the effect of the addition of ampicillin to metronidazole in the prophylaxis of post-appendicectomy wound sepsis. Potential antidepressant effects of novel tropane compounds, selective for serotonin or dopamine transporters. Morphometric analysis of hyperthermia-induced nuclear and nucleolar size modifications in a human melanoma cell line. Approach to the capsule of the prostate by modified Young technique. This suggests that age per se is not a factor in the formation of pressure sores. Multi-method family planning programs are committed to informed free choice of contraceptives. The cases of four patients who received endosseous root-formed implants are discussed.

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Genetic complementation of the Saccharomyces cerevisiae leu2 gene by the Escherichia coli leuB gene. Overproduction of IL-7, IL-10 and TGF-beta 1 in multiple myeloma. A total of 170 Staphylococcus aureus strains isolated during a one-year period at the University Hospital of Patras Medical School were examined for resistance to a battery of antimicrobial agents by disk diffusion and minimum inhibitory concentration (MIC) determination. Particular problems arise from the fact that in interpandemic periods the population is composed of individuals with varying degrees of immunity. Heart scintigraphy by means of stannous pyrophosphate labelled with technetium-99m in the diagnosis of myocardial infarct. Thirty-one lesions were in the head and neck, 24 in the extremities, seven in the pelvis, and five in the ribs. Decreased salivary glucose secretory rate: usefulness for detection of diabetic patients with autonomic neuropathy. Using gel filtration and high pressure liquid chromatography techniques, the main peak of immunoreactive NMB coeluted with synthetic NMB. We estimate that the average age at pension among crane drivers is only about 0.8 that of maintenance workers, regardless of the method, although the confidence intervals depend on the method.

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The amino acid metabolism in GSD-III was shown to differ from that observed in normal subjects and in type I glycogen storage disease (GSD-I) patients. The initial diagnosis was of ventricular tachycardia (VT) and she was treated with intravenous anti-arrhythmic drugs and electrical cardioversion, but to no effect. Duration of the interval between Q and first sound in normal subjects and in various diseases. Verapamyl inhibits vasospasm, abolishes fibrinogen but does not affect cell infiltration and oedema development. The appearance of stress on the movement apparatus in dressage, jumping and versatility horses. There were also no significant differences in the pregnancy and live birth rates per cycle commenced or per embryo transfer. Periorbital congenital melanocytic nevus associated with ankyloblepharon. Although it correlates with some surrogate markers of disease activity and the BVAS, the DEI quantifies different domains of the disease than the BVAS and should therefore be used in conjunction with the BVAS.

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Observations on the number of available C antigen sites on red cells. In this report some preliminary data after magnetic stimulation of the peripheral nerves in 8 normal individuals are presented. After the exhaustion of the glucose from the growth medium the adenylate energy charge, the pools of ATP and total adenylate started to decrease marking the onset of the stationary growth phase. Highly specific and sensitive radioimmunoassays for HTSH, HFSH and HLH have been used in order to investigate pituitary thyrotrophic and gonadotrophic functions of pregnant and puerperal women. Meningeal carcinomatosis is a serious complication of solid tumors, particularly adenocarcinomas of breast, lung and melanoma. Stimulation single fiber electromyography (SFEMG) was done on the biceps femoris muscle at 1, 5, 10 and 20 Hz on the 28th day. Before and at the end of the treatment digital skin microcirculation was measured with a laser Doppler flowmeter. Evidence for an important social role of allogrooming in a platyrrhine primate.

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Electron microscope study of sporulation and parasporal crystal formation in Bacillus thuringiensis. The association has been particularly well-studied for coronary heart disease. An improved method for reinforcing freeze-fracture replicas, which is especially suitable for tough tissues, is described. The Independent Living Training Program is based on an approach to PAS that incorporates a case management model that supports the principles of consumer empowerment and self-determination. Evidence for an unknown component of pancreatic ascites that induces adult respiratory distress syndrome through an interleukin-1 and tumor necrosis factor-dependent mechanism. Furthermore, asymmetrical vestibular righting (i.e., when the young are held laterally in the air) developed before symmetrical vestibular righting (i.e., when held downward by the pelvis or placed supine in water). Monoclonal antibodies to human glomerular cells: a marker for glomerular epithelial cells. In contrast to previous studies examining requirements for Sos phosphorylation following insulin and epidermal growth factor receptor engagement, we show that TCR-induced phosphorylation of Sos does not require activation of the mitogen-activated protein kinase/extracellular-signal regulated kinase (MEK/ERK) pathway. Segments of human saphenous vein obtained from patients undergoing coronary artery bypass surgery were sutured at each end to PTFE and placed into a flow system.

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The folding of the peptide chain of the beef heart ADP/ATP carrier in the inner mitochondrial membrane was investigated by enzymatic and immunochemical approaches, using specific proteases and polyclonal antibodies directed against the whole protein and specific regions of the carrier. The human tRNA(Lys)3 gene was used as a target for transposition in a plasmid-based assay to determine whether Ty3 integration can be targeted to a human tRNA gene. Phosphodiesterase activity was not detected until shortly before birth. The second paper is a statistical attempts, their numbers and their repetition, according also to the sex of the patients. The study presented here represents the first step towards the rational design of such therapeutic agents.

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These observations demonstrate the consistent occurrence of peroxisomes in the heart of various mammalian species and suggest that peroxisomes have important metabolic and physiological functions in myocardium. Our results indicate that gamma-TIP/VM 23 and PIP1 homologous proteins show a similar expression pattern. The anatomy of the ligaments of the wrist and distal radioulnar joints. Device for automatic observation of patients with cardiac rhythm disorders. Narcolepsy, was first described in 1880, is a chronic, disabling disease characterized by excessive daytime sleepiness and abnormal REM manifestations. Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal. Low-dose spiral computed tomography (CT) shows promise as a screening test for lung cancer, as it detects many more malignant pulmonary nodules than does standard plain radiography of the chest. Despite considerable progress, pharmacological therapies have not provided a complete solution for common cardiovascular problems, including recurrent thrombosis, restenosis, and vein graft deterioration. Endoscopic retrograde cholangiopancreatography (ERCP) revealed that the main pancreatic duct and its branches were displaced around the mass in the head of the pancreas.

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The specific activity, molecular weight and immunological behavior of pure dipeptidyl carboxypeptidase from rabbit seminal fluid were found to resemble the corresponding properties of the pulmonary rather than the testicular isozyme. There was a delay in establishing a definite diagnosis in most cases as this depended upon the isolation of R. Concomitants of excess coronary deaths--major risk factor and lifestyle findings from 10,359 men and women in the Scottish Heart Health Study. What happens when growth hormone is discontinued at completion of growth?. The FRA10B locus was located in a transitional region between early and late zones of replication. Immune responsiveness of splenocytes after chronic daily melatonin administration in male Syrian hamsters. When liposomes contained THF, targeted cells survived in the presence of quantities of Mtx in the medium sufficient to eliminate non-targeted cells. Neonatal suprachiasmatic nucleus lesions: effects on the development of circadian rhythms in the rat.

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Hypothalamic sites of action for testosterone, dihydrotestosterone, and estrogen in the regulation of luteinizing hormone secretion in male sheep. Arterial dissection with use of catheter needle in retrograde femoral arteriography. Open heart surgery immediately after the attack is generally considered contraindicated due to problems of hemorrhagic infarction or brain edema. The attitudes of working people toward disabled persons, especially in regard to vocational rehabilitation. These findings suggest that multiple gephyrin proteins are active in the brain and that some of their roles may require functional modulation by limited proteolysis. To elucidate the origin of TE, W/Wv mice, which genetically lack germ cells, were used. Human tactile discrimination of curvature when contact area with the skin remains constant. Enhanced downregulation of Lck-mediated signal transduction by a Y114 mutation of herpesvirus Saimiri tip. Previous work has determined the extent of surface wear occurring on a stainless steel surface within the food industry, and we have reproduced representative samples in vitro.

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The model takes into account mono- or di- or trivalent ions and allows also for modeling of highly acidic or alkaline electrolytes, where a presence of hydrogen and hydroxide ions is significant. The fatty acid composition of fractionated phospholipids and neutral lipids was analyzed in human breast cancer tissues and the surrounding, apparently healthy tissue. There was a downward shift of the lower part of the 4th ventricle during flexion in 4 cases but no change in shape was noted. Orphan receptors COUP-TF and DAX-1 as targets in disordered CYP17 expression in adrenocortical tumors. Some topics for continuing education favored by the dentists were anesthesiology in its broad sense including emergency relief and the study of systemic control, anesthesiology in its restricted sense, oriental medicine, and other topics such as injection, medical dispute, questioning, and clinical inspection. The advantages and disadvantages of bolus injection vs continuous infusion protocols are discussed. Effect of oleic acid on insulin secretion by the isolated perfused rat pancreas. The finding of a vasopressin-resistant hyposthenuria is consistent with the natriuresis of immersion being due, at least in part, to a decrease in sodium reabsorption proximal to the diluting segment, possibly the proximal tubule. Rat parotid gland was dissociated by sequential collagenase and hyaluronidase digestions, chelation with ethylenediaminetetraacetic acid, and mild shearing force to yield predominantly single cells.

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Predicting physical and chemical water properties from relationships with watershed soil characteristics. The onset of DNA synthesis in myogenic precursor cells was determined by injecting each mouse once with tritiated thymidine at a specific time after the second injury. Guidelines of the Working Party on Infections in Hematology and Oncology. Lipid peroxidation is often discussed as a cause of metal-induced toxicity, although many other authors suggest a pivotal role of interaction with sensitive SH groups in determining cadmium and lead toxicity. Factor analysis and predictive validity of microcomputer-based tests. To appreciate the efficiency of biocontrol of the infectious diseases of conifer seedlings, we introduced several indigenous Trichoderma strains into the nursery soil and found that generic prilosec 40 mg this affected the species composition of soil microflora considerably.

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Variations in the depth of the free space in front of the medulla, pons and spinal cord during movement were also noted. The intraepithelial regulatory mechanism of the oral mucous membrane can be disturbed by exogenous and endogenous factors, as a result of which it is possible for the mucosa to lose part of its resistance to external influences. This paper presents a thermodynamic description of the interaction between divalent protein in solution and monovalent ligand attached to a cell membrane, but freely mobile therein. The Milch technique for reduction of anterior shoulder dislocations in an accident and emergency department. Long-term observation may be necessary to make a definite conclusion possible. Regulation of sterol synthesis in cultured cells by oxygenated derivatives of cholesterol.

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An improved method for semen alpha-L-fucosidase typing--distribution in the Wuhan population of China. Neonatal pigs suffer from anemia, and the decrease in the synthesis of UF protein in late pregnancy was suggested to be partly responsible for this condition. This study provides some empirical data on these assumptions by comparing the construction of self and others on repertory grids. This paper considers the prevalence of natural infections of the protozoan Hemolivia mariae, in its hosts the Australian sleepy lizard, Tiliqua rugosa, and the ixodid tick species, Amblyomma limbatum. Normally, the realization depends on individual initiatives and the use of laboratories mainly designed for pediatrics and human genetics. This model has substantially reduced bed stay, with considerable savings to the Hunter Area Health Service manifested as an increase in beds available for other purposes. The significance of a nuclear inclusion body which is present is unclear at this time. Corticotropic and somatotropic cells were seen only rarely, and mammotropic cells were undetectable. Changes in spirometry during consecutive admissions for infective pulmonary exacerbations in adolescent and adult cystic fibrosis. DHEA induced a albenza where to buy slight increase in serum IGF-I, but only in patients with primary AI, suggesting a growth hormone-mediated effect.

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We compared a sample of 40 strains of Candida albicans isolated from the buccal mucosa of HIV-infected patients with 40 strains isolated from non-HIV patients. Dynamics of sleep and the waking state after labyrinthine deafferentation. Cultured adult rat ventricular cardiac muscle cells were treated with either 12-O-tetradecanoyl-phorbol-13-acetate (TPA) or diacylglycerol (DAG) and observed by in situ transmission electron microscopy. To examine some of the possible causes of this difference, immature or pubertal male rats were anesthetized with ketamine HCl and received 3 i.v. It has activity against both the positive and negative symptoms of schizophrenia, which has made it an alternative to traditional antipsychotic medications such as haloperidol. The salivary bypass tube is described and illustrated in detail along with the technique for its insertion and removal. Sural nerve immune deposits in polyneuropathy as a remote effect of malignancy. This paper provides an overview of the motivation and structure of PROforma, and illustrates its use in the development of clinical applications.

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Histologically the lesion was morphea in type and multifocal in origin, arising both in the epidermis and the hair follicle sheath. Pituitary adenoma is a remediable cause of visual disturbance in the elderly. Avian embryos and tissue culture in the study of parasitic protozoa. Evolutionary singular points are shown to occur at extrema of D0. Here, we have used the yeast two-hybrid system to identify Arabidopsis proteins interacting with Cdc2aAt. An inability to relax during repetitive movements might play an important role both in initiating and upholding muscle pain. Neutrophils pretreated with granulocyte colony-stimulating factor (G-CSF) are not related to the severity of endotoxin-induced lung injury. Angiitis involving arterioles and interlobular arteries was observed in 17 out of 42 cases with diffuse proliferative lupus GN.

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Association of Raynaud phenomenon with capillary morphologic changes in patients with lupus erythematosus. Kidney mitochondrial function, as determined by in vitro measurements of citrate-stimulated respiratory rates and specific activities of isocitrate dehydrogenase, succinate dehydrogenase, malate dehydrogenase, and cytochrome c oxidase, appears to be unaffected by environmental heat. Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques. The most recent published guidelines regarding management of patients surviving an acute myocardial infarction (AMI) advocate the administration of aspirin (ASA), beta blockers (BB), and angiotensin-converting enzyme inhibitors (ACEi) and discourages the use of calcium-channel blockers (CCB). This effect was enhanced in animals which had pretreated with reserpine to deplete catecholamines.

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The cysteine proteinase was similar in some properties to rabbit liver cathepsin B, but the enzyme from the tumor-host system showed a remarkable stability to a moderately alkaline pH. The diagnoses of accelerated hypertension or panic disorder often are prematurely adopted. One, found to be kidney-specific, is localised at the apical part of the cells of the proximal segment of the secretory tubules. The administration in vivo of estradiol-17beta (40 mug) 1 hr prior to sacrifice stimulated an increase in nuclear receptor content early in pregnancy (days 3,6,8,10-12) but not later in pregnancy (15,18,20, and 22,). Some of the isoforms of commercial pepsin do not exhibit immunogenic properties, although reveal the enzymic activity. Superoxide production and electron transport in mitochondrial oxidation of dihydroorotic acid. Total lipids were extracted in CO2 atmosphere, dried, and weighed. The aim of this article is to briefly review recent theories about spatial hemineglect with emphasis on their potential use for practice, assessment strategies, and rehabilitative approaches. The slide agglutination test was in complete agreement with the direct immunofluorescence assay, and the serogroup to which 64 clinical isolates of Legionella belonged was correctly identified.

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Pneumostratigraphic examination of the adrenal glands and kidneys. pylori infection on GERD treatment have also arisen in recent years. Pore-gradient electrophoresis was used to examine the distribution of soluble lens proteins. Whereas wild-type ftz homeodomain binds preferentially to a CCATTA motif, the mutant homeodomain (ftzQ50K) recognizes a GGATTA motif. This compound also was reproducibly active against two colon tumors, a mammary tumor, and the intracerebrally implanted P-388 leukemia model. A new computer memory for biology and medicine using the laser card. Healing of a corneal alkali wound was followed flagyl yeast infection medicine in the monkey eye (Macaca fascicularis) for 4 months.

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Incubation of the binding protein with PM2 or polyoma DNA results in the formation of a fast sedimenting DNA structure in neutral sucrose gradients. A highly statistically significant correlation (p less than 0.0001) between tumor diameter and success or failure of surgical extirpation was demonstrated for the total of 241 gastric leiomyosarcomas in the present series and collected from the literature. Total lateral ventricular volume ranged from 77 mm3 to 11,726 mm3. In hatchlings, high metabolic rates coincided with low growth rates in turkeys and guinea fowl. To date, little is known about the effects of an adverse environment on the growth of the spinal canal, and no data have been reported on antenatal influencing factors. A mixture of human MAbs with specificity to CPS of clinically important Klebsiella serotypes may prove to be a useful tool for the prevention or supportive treatment of Klebsiella pneumonia. The antigens identified by these three mAbs were characterized biochemically, by enzymatic digestion of RA synovial tissue m phi s followed by a cellular ELISA, as well as by reactivity of the mAbs with NIH-3T3 cells genetically engineered to express known myeloid antigens.

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