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Amixide (Amitriptyline)
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Amixide

Amixide is a medicine used for treating pain. You can take it: to treat nerve pain (neuralgia) and back pain. to help prevent migraine attacks. The FDA withdrew the drug in 2000 following reports that it increased the risk of heart problems. Doctors may still prescribe the drug, but only in rare cases when it is necessary.

Other names for this medication:
Abamax, Amiclozor, Amidez, Amiline, Amitar, Amitin, Amitrac, Amitrip, Amitriptyline, Amitrol, Amitryptyline, Amitwix, Amizep, Amoten, Amsha, Amtipax, Amtran, Amypres, Anitryp, Aptric, Eliwel, Emotrip, Eptanol, Estiline, Gentrip, Kamitrin, Libral, Raitrip, Relidep, Ronet, Teedep, Typlin

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Also known as: Amitriptyline

Description

Amixide target is the treatment of depression. Amixide is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amixide is Amitriptyline. Amixide is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amixide are Amixide, Endep, Vanatrip.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amixide dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amixide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Amixide if you are allergic to Amixide components. Do not take Amixide if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amixide if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amixide if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amixide you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amixide if you are going to have a surgery. It can be dangerous to stop Amixide taking suddenly.

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Two hundred and eighty-three patients were admitted to a randomized, prospective and double-blind trial of the effect of the addition of ampicillin to metronidazole in the prophylaxis of post-appendicectomy wound sepsis. Potential antidepressant effects of novel tropane compounds, selective for serotonin or dopamine transporters. Morphometric analysis of hyperthermia-induced nuclear and nucleolar size modifications in a human melanoma cell line. Approach to the capsule of the prostate by modified Young technique. This suggests that age per se is not a factor in the formation of pressure sores. Multi-method family planning programs are committed to informed free choice of contraceptives. The cases of four patients who received endosseous root-formed implants are discussed.

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Genetic complementation of the Saccharomyces cerevisiae leu2 gene by the Escherichia coli leuB gene. Overproduction of IL-7, IL-10 and TGF-beta 1 in multiple myeloma. A total of 170 Staphylococcus aureus strains isolated during a one-year period at the University Hospital of Patras Medical School were examined for resistance to a battery of antimicrobial agents by disk diffusion and minimum inhibitory concentration (MIC) determination. Particular problems arise from the fact that in interpandemic periods the population is composed of individuals with varying degrees of immunity. Heart scintigraphy by means of stannous pyrophosphate labelled with technetium-99m in the diagnosis of myocardial infarct. Thirty-one lesions were in the head and neck, 24 in the extremities, seven in the pelvis, and five in the ribs. Decreased salivary glucose secretory rate: usefulness for detection of diabetic patients with autonomic neuropathy. Using gel filtration and high pressure liquid chromatography techniques, the main peak of immunoreactive NMB coeluted with synthetic NMB. We estimate that the average age at pension among crane drivers is only about 0.8 that of maintenance workers, regardless of the method, although the confidence intervals depend on the method.

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Observations on the number of available C antigen sites on red cells. In this report some preliminary data after magnetic stimulation of the peripheral nerves in 8 normal individuals are presented. After the exhaustion of the glucose from the growth medium the adenylate energy charge, the pools of ATP and total adenylate started to decrease marking the onset of the stationary growth phase. Highly specific and sensitive radioimmunoassays for HTSH, HFSH and HLH have been used in order to investigate pituitary thyrotrophic and gonadotrophic functions of pregnant and puerperal women. Meningeal carcinomatosis is a serious complication of solid tumors, particularly adenocarcinomas of breast, lung and melanoma. Stimulation single fiber electromyography (SFEMG) was done on the biceps femoris muscle at 1, 5, 10 and 20 Hz on the 28th day. Before and at the end of the treatment digital skin microcirculation was measured with a laser Doppler flowmeter. Evidence for an important social role of allogrooming in a platyrrhine primate.

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Electron microscope study of sporulation and parasporal crystal formation in Bacillus thuringiensis. The association has been particularly well-studied for coronary heart disease. An improved method for reinforcing freeze-fracture replicas, which is especially suitable for tough tissues, is described. The Independent Living Training Program is based on an approach to PAS that incorporates a case management model that supports the principles of consumer empowerment and self-determination. Evidence for an unknown component of pancreatic ascites that induces adult respiratory distress syndrome through an interleukin-1 and tumor necrosis factor-dependent mechanism. Furthermore, asymmetrical vestibular righting (i.e., when the young are held laterally in the air) developed before symmetrical vestibular righting (i.e., when held downward by the pelvis or placed supine in water). Monoclonal antibodies to human glomerular cells: a marker for glomerular epithelial cells. In contrast to previous studies examining requirements for Sos phosphorylation following insulin and epidermal growth factor receptor engagement, we show that TCR-induced phosphorylation of Sos does not require activation of the mitogen-activated protein kinase/extracellular-signal regulated kinase (MEK/ERK) pathway. Segments of human saphenous vein obtained from patients undergoing coronary artery bypass surgery were sutured at each end to PTFE and placed into a flow system.

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The folding of the peptide chain of the beef heart ADP/ATP carrier in the inner mitochondrial membrane was investigated by enzymatic and immunochemical approaches, using specific proteases and polyclonal antibodies directed against the whole protein and specific regions of the carrier. The human tRNA(Lys)3 gene was used as a target for transposition in a plasmid-based assay to determine whether Ty3 integration can be targeted to a human tRNA gene. Phosphodiesterase activity was not detected until shortly before birth. The second paper is a statistical attempts, their numbers and their repetition, according also to the sex of the patients. The study presented here represents the first step towards the rational design of such therapeutic agents.

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These observations demonstrate the consistent occurrence of peroxisomes in the heart of various mammalian species and suggest that peroxisomes have important metabolic and physiological functions in myocardium. Our results indicate that gamma-TIP/VM 23 and PIP1 homologous proteins show a similar expression pattern. The anatomy of the ligaments of the wrist and distal radioulnar joints. Device for automatic observation of patients with cardiac rhythm disorders. Narcolepsy, was first described in 1880, is a chronic, disabling disease characterized by excessive daytime sleepiness and abnormal REM manifestations. Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal. Low-dose spiral computed tomography (CT) shows promise as a screening test for lung cancer, as it detects many more malignant pulmonary nodules than does standard plain radiography of the chest. Despite considerable progress, pharmacological therapies have not provided a complete solution for common cardiovascular problems, including recurrent thrombosis, restenosis, and vein graft deterioration. Endoscopic retrograde cholangiopancreatography (ERCP) revealed that the main pancreatic duct and its branches were displaced around the mass in the head of the pancreas.

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The length of the fragment was 3179, including the entire 51st exon and partial 50th and 51st intron sequences. Suramin and the inhibitory junction potential in taenia caeci of the guinea-pig. In this study, we confirmed these findings by means of a time-course study, and further investigated whether the elevated plasma basal glucocorticoid level induced by repeated stress underlies the attenuated response of immediate early genes and the preserved reactivity of NGFI-A. In contrast, C-peptide secretion during arginine infusion following i.v. It was demonstrated that Illinois virus caused marked effect on the intestine: shortening of the villi, intestinal distension, edema, and presence of accumulated intestinal fluid within 60 hours after inoculation. Color Doppler echocardiographic evaluation of tricuspid regurgitation and systolic pulmonary artery pressure in the full-term and preterm newborn. Research on the exoerythrocytic (EE) stages of human malaria parasites has been hindered because of the lack of an easily available suitable animal model.

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The specific activity, molecular weight and immunological behavior of pure dipeptidyl carboxypeptidase from rabbit seminal fluid were found to resemble the corresponding properties of the pulmonary rather than the testicular isozyme. There was a delay in establishing a definite diagnosis in most cases as this depended upon the isolation of R. Concomitants of excess coronary deaths--major risk factor and lifestyle findings from 10,359 men and women in the Scottish Heart Health Study. What happens when growth hormone is discontinued at completion of growth?. The FRA10B locus was located in a transitional region between early and late zones of replication. Immune responsiveness of splenocytes after chronic daily melatonin administration in male Syrian hamsters. When liposomes contained THF, targeted cells survived in the presence of quantities of Mtx in the medium sufficient to eliminate non-targeted cells. Neonatal suprachiasmatic nucleus lesions: effects on the development of circadian rhythms in the rat.

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Pneumostratigraphic examination of the adrenal glands and kidneys. pylori infection on GERD treatment have also arisen in recent years. Pore-gradient electrophoresis was used to examine the distribution of soluble lens proteins. Whereas wild-type ftz homeodomain binds preferentially to a CCATTA motif, the mutant homeodomain (ftzQ50K) recognizes a GGATTA motif. This compound also was reproducibly active against two colon tumors, a mammary tumor, and the intracerebrally implanted P-388 leukemia model. A new computer memory for biology and medicine using the laser card. Healing of a corneal alkali wound was followed flagyl yeast infection medicine in the monkey eye (Macaca fascicularis) for 4 months.

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Incubation of the binding protein with PM2 or polyoma DNA results in the formation of a fast sedimenting DNA structure in neutral sucrose gradients. A highly statistically significant correlation (p less than 0.0001) between tumor diameter and success or failure of surgical extirpation was demonstrated for the total of 241 gastric leiomyosarcomas in the present series and collected from the literature. Total lateral ventricular volume ranged from 77 mm3 to 11,726 mm3. In hatchlings, high metabolic rates coincided with low growth rates in turkeys and guinea fowl. To date, little is known about the effects of an adverse environment on the growth of the spinal canal, and no data have been reported on antenatal influencing factors. A mixture of human MAbs with specificity to CPS of clinically important Klebsiella serotypes may prove to be a useful tool for the prevention or supportive treatment of Klebsiella pneumonia. The antigens identified by these three mAbs were characterized biochemically, by enzymatic digestion of RA synovial tissue m phi s followed by a cellular ELISA, as well as by reactivity of the mAbs with NIH-3T3 cells genetically engineered to express known myeloid antigens.

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