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Amoxicillinum (Amoxicillin)
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Amoxicillinum

Amoxicillinum is an antibiotic. It's used to treat bacterial infections, such as chest infections (including pneumonia), dental abscesses and urinary tract infections (UTIs). It's used in children, often to treat ear infections and chest infections. The medicine is only available on prescription.

Other names for this medication:
Acimox, Alfamox, Aloxyn, Amoclen, Amoksicilin, Amopen, Amoram, Amoxi, Amoxicilina, Amoxicillin, Amoxicillinum, Amoxiline, Amoxisol, Amoxivet, Amoxypen, Amurol, Bimoxan, Bristamox, Cipmox, Clamoxyl, Flemoxin, Flemoxon, Galenamox, Gimalxina, Hidramox, Hydramox, Larotid, Lupimox, Moxicillin, Novamoxin, Ospamox, Penamox, Penimox, Polymox, Raylina, Reloxyl, Robamox, Sintedix, Stacillin, Sumox, Tolodina, Utimox, Velamox, Wymox

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Also known as: Amoxicillin

Description

Amoxicillin is used to treat bacterial infections in many different parts of the body. It is also used with other medicines (e.g., clarithromycin, lansoprazole) to treat H. pylori infection and duodenal ulcers.

Amoxicillin belongs to the group of medicines known as penicillin antibiotics. It works by killing the bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

Adults: 1 g PO once daily or 500 mg PO twice daily for 10 days. The American Heart Association (AHA) recommends extended-release Amoxicillinum as an alternative to penicillin V for rheumatic fever prophylaxis.

Infants, Children, and Adolescents: 25 mg/kg/dose (Max: 500 mg/dose) PO twice daily for 10 days is recommended by the Infectious Diseases Society of America (IDSA). Alternatively, 50 mg/kg/dose PO once daily (Max: 1 g/dose) for 10 days is recommended by The American Heart Association (AHA) as an alternative to penicillin V. For ear/nose/throat infections in general, the FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Amoxicillinum are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Amoxicillinum.

Crystalluria, in some cases leading to renal failure, has also been reported after Amoxicillinum overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Amoxicillinum crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Amoxicillinum. Amoxicillinum may be removed from circulation by hemodialysis.

Storage

Store this medicine at room temperature, away from heat, light, and moisture.

Side effects

The most common side effects associated with Amoxicillinum are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of amoxicillin in children. However, newborns and infants 3 months of age and younger have incompletely developed kidney functions, which may need a lower dose of this medicine.

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A parallel histoenzymatic and electron-microscopy study of the state of mitochondria in experimental viral cancerogenesis induced by adenovirus of monkeys SA7(C8) and virus of Rous sarcoma in soft tissues of hamster was carried out. Chick embryo pancreatic transplants reverse experimental diabetes of rats. The purpose of this State-wide study was to identify the most important competencies expected of first-line nursing managers. The underlying mechanism being atrial fibrillation with a very high ventricular rate, because of a short anterograde refractory period of the accessory atrioventricular pathway (AP), deteriorating into ventricular fibrillation. The separate foci of both ipsilateral and contralateral terminations in posterior parietal cortex raise the possibility that this region contains more than one functional subdivision.

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Patient communication systems and the opportunities they offer are explored. Two novel benzodiazepines, 2,2,4-trimethyl-1H-2,3,4,5-tetrahydro-1,5-benzodiazepine (3) and 1-cinnamoyl-2,2,4-trimethyl-1H-2,3,4,5-tetrahydro-1,5-benzodiazepine (4), were synthesized by the reduction of 1 and 2 using NaBH4 in i-PrOH and two other derivatives 5 and 6 were obtained by reaction of 4 with equimolar and dimolar quantity of cinnamoyl chloride, respectively. The inhibition of the production of TNF-alpha and IL-1 beta by procaterol was additively potentiated with theophylline. However, the extent to which these hormonal systems influence autonomic reflexes during the fetal and newborn period appears vastly different than in the adult. In this scenario the LCMV-induced immune response is directed not only against the virus but also against the LCMV transgenes expressed in the beta cells. As compared to the control group the trained subjects had significantly imovane overdose higher values in the muscle malate dehydrogenase, succinate dehydrogenase and prolyl hydroxylase activities, whereas the opposite was true in the activity of lactate dehydrogenase. Atrial natriuretic peptide-C receptor and membrane signalling in hypertension. We stress the importance of definite assessment of the communication of pancreatic pseudocyst with mediastinum in patients with pancreatitis who develop recurrent pleural effusions. In these patients, MMSE scores were significantly different among the seven diagnostic groups included. For comparative purposes we also used B9 cells, which express the granulocyte-macrophage colony stimulation factor (GM-CSF) and had been derived from 123A cells by transduction with the recombinant adeno-associated virus carrying the HSV TK gene and the mouse GM-CSF gene.

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Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene. Shortcomings of most DUE information systems include patient identification problems, defects in database design, and lack of software to identify prescribing problems and perform statistical analysis. The exercise pressor reflex: its cardiovascular effects, afferent mechanisms, and central pathways. Comparative serological and cutaneous reactivity of candidal cytoplasmic proteins and mannan separated by affinity for concanavalin A. Neither was there any significant (P greater than 0.05) difference between the surviving caponized and uncaponized toms in the development of serum anti-P. The changes in MADR2 expression were accompanied by reciprocal alterations in the expression of cPLA2. Left hemispheric strokes in coronary surgery: implications for end-hole aortic cannulas. The antidepressants did not change the development of tolerance to ethanol.

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