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Amoxiline (Amoxicillin)
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Amoxiline

Amoxiline may be recommended to treat infections of the nose, ears, throat, urinary tract, or skin. It can also be used for pneumonia, tonsillitis, or bronchitis. Sometimes it’s given with other medicines to get rid of H. pylori, a species of bacteria that causes ulcers.

Other names for this medication:
Acimox, Alfamox, Amoclen, Amoksicilin, Amopen, Amoram, Amoxi, Amoxicilina, Amoxicillin, Amoxisol, Amoxivet, Amoxypen, Bristamox, Cipmox, Clamoxyl, Flemoxin, Galenamox, Larotid, Lupimox, Moxicillin, Ospamox, Penamox, Penimox, Polymox, Reloxyl, Servamox, Sintedix, Tolodina, Wymox, Zimox

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Also known as: Amoxicillin

Description

Amoxicillin is used to treat bacterial infections in many different parts of the body. It is also used with other medicines (e.g., clarithromycin, lansoprazole) to treat H. pylori infection and duodenal ulcers.

Amoxicillin belongs to the group of medicines known as penicillin antibiotics. It works by killing the bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

Adults: 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections.

Infants 6 months and older, Children, and Adolescents: 80 to 90 mg/kg/day PO in divided doses every 12 hours is recommended by the American Academy of Pediatrics (AAP) as first-line therapy. Do not exceed 500 mg/dose if given every 8 hours or 875 mg/dose if given every 12 hours. AAP recommends a 10-day course for any child with severe disease and for all patients less than 2 years of age, regardless of severity. For children 2 to 5 years with mild to moderate disease, a 7-day course is acceptable. For children 6 years and older with mild to moderate disease, a 5- to 7-day course is acceptable. The FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Infants 4 to 5 months: 80 to 90 mg/kg/day PO given in divided doses every 12 hours for 10 days was recommended by experts as first-line therapy in previous guidelines ; however, this age group is not addressed in the most current guidelines by the American Academy of Pediatrics (AAP). The FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours or 25 mg/kg/day PO in divided doses every 12 hours for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours or 45 mg/kg/day PO in divided doses every 12 hours for severe infections.

Infants 3 months and younger: 30 mg/kg/day PO given in divided doses every 12 hours is the general FDA-approved dosing. Young infants are less capable of responding to infection, and the clinical manifestations of infection can be subtle. Because of the increased risk for complications of an undiagnosed systemic infection, every young infant presenting with a fever should be carefully evaluated.

Overdose

If you overdose Generic Amoxiline and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

You may store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days. Do not freeze.

Detailed Amoxiline dosage information

Side effects

The most common side effects associated with Amoxiline are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Geriatric. Based on manufacturer data, geriatric patients (above 65 years) do not respond differently to Amoxiline treatment than younger patients. However, a greater sensitivity to Amoxiline in elderly patients could not be ruled out. Amoxiline is known to be substantially excreted via the kidney. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection for elderly patients; renal function monitoring may be useful. The federal Omnibus Budget Reconciliation Act (OBRA) regulates medication use in residents of long-term care facilities. According to OBRA, use of antibiotics should be limited to confirmed or suspected bacterial infections. Antibiotics are non-selective and may result in the eradication of beneficial microorganisms while promoting the emergence of undesired ones, causing secondary infections such as oral thrush, colitis, or vaginitis. Any antibiotic may cause diarrhea, nausea, vomiting, anorexia, and hypersensitivity reactions.

Pregnancy. Amoxiline is classified in FDA pregnancy risk category B. Animal data reveal no teratogenic effects, however, there are no adequate and well-controlled studies in pregnant women. While Amoxiline should be used with caution in pregnancy, penicillins are usually considered safe during pregnancy when clearly needed.

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The benefits and risks of episiotomy in labor and delivery as recorded in the English language literature in over 350 books and articles published since 1860 are reviewed and analyzed. Intralobar pulmonary sequestration treated surgically in a patient with sarcoidosis. Most cases remain asymptomatic for an extended period of time, and many have no identifiable risk factors. Epinephrine infusions given alone produced sustained elevations of glycerol and FFA. Effect on the heart of experimental arteriovenous aneurysms of long duration. The aim of this study was to relate the various clinical presentations of acute coronary syndromes to the underlying plaque morphology as assessed from histopathologic analysis of plaque fragments obtained by directional coronary atherectomy (DCA).

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To clarify the significance of immunoreactive carcinoembryonic antigen in gastric juice (gastric CEA) from gastric cancer patients, we studied the gastric CEA in comparison with cancer progress, histologic types of tumors, staining for CEA and extent of intestinal metaplasia. Recent progress in monoclonal research has led to interspecific fusion of murine myelomas with bovine lymphocytes, resulting in hybridomas that produce monoclonal bovine immunoglobulins. We suggest that autologous serum deprivation restored and enhanced IL-1ra production, and normalized the cytokine cascade in immune response, in patients with gastric cancer. Chronic rejection is assumed to be the principle cause of airway injury leading to obliterative bronchiolitis (OB) after lung transplantation (Tx). Myocardial release of inosine, hypoxanthine and lactate during pacing-induced angina in humans with coronary artery disease. Prevention of the chronic complications of type 2 diabetes: A consensus from the Mexican Society of Nutrition and Endocrinology, the Mexican Association of Internal Medicine, and the Society of Nutriology. Penetration of the pulp chamber by bleaching agents in teeth restored with various restorative materials. Following revaccination no increase of lymphocyte transformation ratio could be observed in 11 persons studied. By this method, the number of asbestos bodies detected in men was significantly higher than that in women. So far though, as shown in our summary of current knowledge on established and dubious risk factors, no risk factors have been identified that can explain a major part of the incidence.

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