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Amtran (Amitriptyline)

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Amtran is a type of drug called a tricyclic antidepressant. Amtran works by increasing the amount of serotonin your brain makes. These drugs were originally developed to treat anxiety and depression, but when taken at a low dose they can reduce or stop pain.

Other names for this medication:
Abamax, Amiclozor, Amicon, Amicure, Amiline, Amitar, Amitrac, Amitriptyline, Amitrix, Amitrol, Amitryn, Amitryptyline, Amitwix, Amity, Amize, Amizep, Amline, Amsha, Amtipax, Amtran, Anitryp, Aptric, Arpidox, Bluneel, Chlotrip, Eliwel, Eptanol, Estiline, Gentrip, Latiln, Libral, Limbitrol, Limbival, Lodep, Maxitrip, Mitrip, Mitryp, Nextrip, Normaline, Psycomer, Raitrip, Relidep, Sarotena, Tadamit, Triplent, Trixide, Tryline, Typteez, Vanatrip, Zodep

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Also known as: Amitriptyline


Amtran target is the treatment of depression. Amtran is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amtran is Amitriptyline. Amtran is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amtran are Amtran, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amtran dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amtran are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amtran if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amtran if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amtran is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amtran is not approved for use by anyone younger than 12 years old.

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In vivo metabolism of tritiated LHRH by the whole kidney and individual tubules of rats. We studied the effects of low-dose (3 MU daily) human recombinant IFN-alpha 2b for 6-12 months in 29 consecutive cases of previously untreated, stable-phase, early stage, monoclonal gammopathy (MG) (23 cases of stage I MM and six cases of IgM MG). Cells were fused to mitotic V79 cells immediately after exposure to examine initial chromatin breakage or after various time intervals of post-irradiation incubation to investigate the kinetics of chromatin break rejoining as well as the fraction of unrejoined fragments. Etanercept is being tried in patients with congestive heart failure, where TNF-a seems to be increased. Lipopolysaccharide is present in immune complexes isolated from sputum in patients with cystic fibrosis and chronic Pseudomonas aeruginosa lung infection. The interpretation of the competencies offered here should prove to be a useful tool to nurses and health system leaders as they carry on the hard work of adapting the current model of nursing practice to the demands and realties of the contemporary and continually evolving health care environment. Blood on filter paper as a readily available source of bcr-abl rearranged mRNA. The disposition profile of amiloride, a potassium sparing agent, was studied in rats by using an HPLC method coupled to spectrofluorometric detection. In all three patients, resolution was slow but eventually complete. Use of aminoglycoside antibiotics and related compounds to study ADP-ribosylation factor (ARF)/coatomer function in Golgi traffic.

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Ten brains from previously CT-scanned patients in this group were sectioned in the plane of the scan. Presence of sequences hybridisable to dsRNA in cytoplasmic mRNA molecules. The cellular prion protein of the mouse, mPrP(C), consists of 208 amino acids (residues 23-231). The spread of the HIV/AIDS epidemic to children has become one of the most serious public health problems in the United States. Implant angulation is of utmost importance for fabrication of esthetic, hygienic, and functional prostheses, even in the treatment of completely edentulous patients. Comparison of inhibitors of S-adenosylmethionine decarboxylase from different species. A complex but permeable network of intercellular spaces provides a path for possible transfollicular penetration for the exogenous fraction of the vitellus. Serum bilirubin: a prognostic factor in primary biliary cirrhosis. One of the survivors died with apparent pneumonia 1 month postoperatively.

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Rubinstein-Taybi syndrome: objective evaluation of craniofacial structure. In the patient who was retested after clinically successful prednisone therapy, the REM sleep pattern had become normal. Determination of the molecular weight of bovine enterovirus RNA by nuclease digestion. Maximum and minimum discharge rates in IFD neurons occurred near maximum chair velocities, whereas the phase shift decreased in HFD neurons, which had higher discharge rates during the horizontal chair position. The changing healthcare environment is challenging home healthcare nurses to rethink what they do and how they do it, and explore innovative approaches to improve client satisfaction.

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The benefit of graded physical exercise in chronic heart failure. Food microbiology into the twenty-first century--a Delphi forecast. Patients with documented HIV infection were evaluated for rheumatic disease using a standardized questionnaire and examination. However, the enzyme is elevated constantly and all the time in these conditions, in contrast with its elevation in uncontrolled epilepsy only close to the seizures. The theory and definition of NUN in space and in time, and NUN climatic (convective, radiant, perspiratory) and NUN conductive are described. typhimurium transconjugates show decreased virulence in both enteral and intraperitoneal infection of mice. Primary structure of a ribonuclease from bullfrog (Rana catesbeiana) liver. Though no depleted uranium was detected in air by the sensitive technique of alpha-spectrometry, the increased uranium content in natural ratio as a component of normal soil, natural gas, etc., is suggested to originate from well dispersed dust (2.5 microm size) emitted to the atmosphere by explosions during bombing. The periodicity of 10.4 is discussed with respect to the number of base pairs per turn of chromatin DNA and the number of superhelical turns of DNA per nucleosome.

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Leakage in vitro with IRM, high copper amalgam, and EBA cement as retrofilling materials. Approaches to immunological control of virus-associated tumors in man: introductory remarks. Pore properties and ionic block of the rabbit epithelial calcium channel expressed in HEK 293 cells. The individualized approach to the performance of computerized tomography of the skull is described. An altered supply or activity of growth factors may be instrumental. A study of exposure to environmental temperatures in a population sample using the temperature SAMI. External neurolysis was performed in fourteen cases, whereas internal neurolysis involving interfascicular dissection was performed in twenty-three cases. The Heidelberg Retina Flowmeter also measured the expected decrease in volume at the foveolar avascular zone. Retroviruses have long been fascinating to biologists because of their capacity to induce neoplasms in various animals.

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Botulinum toxin as a treatment for blepharospasm, spasmodic torticollis and hemifacial spasm. Leprosy in wild armadillos (Dasypus novemcinctus) of the Texas Gulf Coast: epidemiology and mycobacteriology. Fracture manipulation in the ED is herein reported to be one of the many types of acute traumatic and atraumatic somatic stresses that can cause this serious and occasionally lethal syndrome. The current analysis is based on data from the second National Incidence Study of Child Abuse and Neglect (NIS-2), which collected information from both CPS and non-CPS agencies (e.g., schools, hospitals) in a national sample of 29 counties (Westat, 1988). Clinical use of the kits for laboratory diagnosis: their advantages and normal values. In the past decade evidence has accumulated for local tissue renin-angiotensin systems and for direct trophic effects of angiotensin II. Paired stimuli were delivered to the ventrolateral thalamus with evoked responses recorded from the ipsilateral sensorimotor cortex in the cat. Respiration was measured non-invasively in the unanaesthetized kittens. Thus, out of 72 fusions, only 3 stable hybrids with antibody production against a predefined antigen were established. The two tested type I antiarrhythmics tend to add to myocardial protection when given before cardioplegic arrest and do not exhibit negative inotropic side effects.

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