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Amtran (Amitriptyline)
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Amtran

Amtran is a type of drug called a tricyclic antidepressant. Amtran works by increasing the amount of serotonin your brain makes. These drugs were originally developed to treat anxiety and depression, but when taken at a low dose they can reduce or stop pain.

Other names for this medication:
Abamax, Amiclozor, Amicon, Amicure, Amiline, Amitar, Amitrac, Amitriptyline, Amitrix, Amitrol, Amitryn, Amitryptyline, Amitwix, Amity, Amize, Amizep, Amline, Amsha, Amtipax, Amtran, Anitryp, Aptric, Arpidox, Bluneel, Chlotrip, Eliwel, Eptanol, Estiline, Gentrip, Latiln, Libral, Limbitrol, Limbival, Lodep, Maxitrip, Mitrip, Mitryp, Nextrip, Normaline, Psycomer, Raitrip, Relidep, Sarotena, Tadamit, Triplent, Trixide, Tryline, Typteez, Vanatrip, Zodep

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Also known as: Amitriptyline

Description

Amtran target is the treatment of depression. Amtran is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amtran is Amitriptyline. Amtran is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amtran are Amtran, Endep, Vanatrip.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amtran dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amtran are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Amtran if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amtran if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amtran is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amtran is not approved for use by anyone younger than 12 years old.

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Ten brains from previously CT-scanned patients in this group were sectioned in the plane of the scan. Presence of sequences hybridisable to dsRNA in cytoplasmic mRNA molecules. The cellular prion protein of the mouse, mPrP(C), consists of 208 amino acids (residues 23-231). The spread of the HIV/AIDS epidemic to children has become one of the most serious public health problems in the United States. Implant angulation is of utmost importance for fabrication of esthetic, hygienic, and functional prostheses, even in the treatment of completely edentulous patients. Comparison of inhibitors of S-adenosylmethionine decarboxylase from different species. A complex but permeable network of intercellular spaces provides a path for possible transfollicular penetration for the exogenous fraction of the vitellus. Serum bilirubin: a prognostic factor in primary biliary cirrhosis. One of the survivors died with apparent pneumonia 1 month postoperatively.

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