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Anastrozole

Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

Similar Products:
Kemadrin, Antabuse, Combivent, Fasigyn, Lamisil, Viramune, Dulcolax, Duricef, Plavix

Description

{name} (anastrozole) lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

{name} is used to treat breast cancer in postmenopausal women.

{name} is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox).

Dosage

Usual Adult Dose for Breast Cancer:

Initial dose: 1 mg orally taken once a day Duration of therapy: Until tumor progression (treatment of advanced breast cancer); unknown (adjuvant treatment of early breast cancer) Uses: -Adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer; -First-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer; -Second-line treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.

Detailed Anastrozole dosage information

Overdose

If you overdose Generic Anastrozole and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Anastrozole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Anastrozole can interact with several other medications.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Anastrozole and other medications

Below are lists of medications that can interact with Anastrozole. These lists do not contain all the drugs that may interact with Anastrozole.

Before taking Anastrozole, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Anastrozole and tamoxifen

Like Anastrozole, tamoxifen is a hormone therapy that’s used to treat breast cancer. But taking tamoxifen with Anastrozole can lower the amount of Anastrozole in your body. This can make Anastrozole less effective for you.

Because of this interaction, you shouldn’t take tamoxifen with Anastrozole. However, if recommended by your doctor, it’s fine to take Anastrozole after you’ve finished taking tamoxifen.

Anastrozole and drugs that contain estrogen

Taking Anastrozole with drugs that contain estrogen could make Anastrozole less effective for you. Because of this, you shouldn’t take these types of drugs while you’re using Anastrozole.

Examples of drugs that contain estrogen include:

  • hormone replacement therapy (HRT)
  • vaginal estrogen products, such as creams and tablets
  • birth control medications, such as pills, patches, and vaginal rings
If you have questions about using medications that contain estrogen with Anastrozole, talk with your doctor.

Anastrozole and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Anastrozole. However, you should still check with your doctor or pharmacist before using any of these products while taking Anastrozole.

For example, it’s possible that supplements such as red clover or wild yam could make Anastrozole less effective. (These supplements are used by some women to reduce menopausal symptoms, such as hot flashes.)

This interaction is possible because these supplements contain phytoestrogens, which are weak estrogen-like substances found in certain plants. There isn’t enough information available to say for sure whether taking phytoestrogens can affect your breast cancer treatment or not.

Be sure to talk with your doctor before taking any herbs or supplements with Anastrozole.

Anastrozole and foods

There aren’t any foods that are known to interact with Anastrozole. Talk with your doctor to find out if there are any foods you should avoid during Anastrozole treatment.

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Structural characterization of tatiopterin, a novel pterin isolated from Methanogenium tationis. By use of a new chromogenic substrate, we have shown that the constitutent hyphae of young cleistothecia and the hulle cells which surround the cleistothecia of A. To probe the function of the early region 1b-encoded 55- and 21-kilodalton (kd) polypeptides during this process, a series of viral mutants was engineered so that they contained deletions or insertions at 5.4, 5.7, 7.9, or 9.6 map units. A series of 1,420 Dutch patients with facial fractures was compared with series from three other European countries. Group A had a pregnancy rate of 90 percent requiring 1.7 services per conception. An enzymatic method for distinguishing deoxyuridine and deoxythymidine nucleotide pools and its application for determining ribonucleotide reductase activity. Hirudin was added before thrombin in some experiments, and in other experiments the endothelium was pretreated with 0.5 mM acetylsalicylic acid (ASA).

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