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Anerozol (Metronidazole)

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Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

Other names for this medication:
Amobin, Anerozol, Aristogyl, Avidal, Birodogyl, Buccoval, Cresac, Dequazol, Elyzol, Entizol, Farnat, Fladex, Fladystin, Flagolin, Gynoplix, Klion, Metren, Metrogel, Metrolyl, Metronidazol, Metronidazols, Metropast, Metrosa, Metrosil, Metroson, Metsina, Missilor, Nalox, Nidagyl, Nidazea, Noritate, Promuba, Rhodogil, Riazole, Robaz, Rosaced, Rozex, Supplin, Tricofin, Triconex, Vagilen, Venogyl, Zobacide

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Also known as: Metronidazole


Metronidazole injection is used to treat serious bacterial infections in different areas of the body. It is also used to prevent infections in the bowels before and after surgery for some patients.

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is to be given only by or under the direct supervision of your doctor.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Anerozol. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.


Single oral doses of Anerozol, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Anerozol has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Anerozol overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Anerozol ER dosage information

Side effects

The most common side effects associated with Anerozol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of metronidazole injection in the elderly. However, elderly patients are more likely to have unwanted effects and age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving metronidazole injection.

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Near-infrared fluorescent imaging of transplant recipients at 4 weeks demonstrated focal uptake of scVEGF/Cy in remodeling artery grafts. Magnetic resonance imaging demonstrated a well-demarcated, dura-based mass measuring 7 cm in maximal diameter in the right occipital to parietal area. We have analyzed the ethical implications of a variety of efforts to increase vaccination rates, including mandatory influenza vaccination. Our hybrid, percutaneous and surgical, approach offered acute short-term circulatory support in STEMI patients with acute heart failure, allowing myocardial recovery or selection for long-term mechanical support. How Common are WM Deficits in Children with Difficulties in Reading and Mathematics?. The mode of regulation of Mus81-Mms4 restricts its activity to a short period of the cell cycle, thus preventing its function during chromosome replication and the negative consequences for genome stability derived from its nucleolytic action. The procedures were performed under general anesthesia and using a double-lumen endotracheal tube. The best characterised role of SPY is a negative regulator of GA signalling, and all known spy alleles have been isolated based on increased GA response. We also show analytically that the nodes degree distribution at each layer exhibits a power-law tail with an exponential cutoff. However, this model was not reliably predictive for positive non-SLN in cases with micrometastic positive SLN.

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Relationship between age and semen parameters in men with normal sperm concentration: analysis of 6022 semen samples. All personnel performing or assisting with endoscopic procedures and those responsible for reprocessing the equipment should be trained in how to handle the infectious and chemical hazards associated with the endoscopic environment. The effect of hydraulic conditions on waste stabilisation in bioreactor landfill simulators. The effectiveness of the collagen band showed to be equal to those of fibroblast transplantation. Hydrogen-exchange labeling coupled with NMR was used to monitor the formation of stable hydrogen-bonded and solvent-excluded structure in horse cytochrome c (cyt c). Finally, signal transduction pathways were analyzed by quantifying phosphorylated forms of MAPKs (PI3K, ERK, and p38) and DNA-binding assays that quantified NF-kappaB and its inhibition using BAY11-7085.

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Microsurgical bilateral decompression using unilateral laminotomy is an effective surgical option for lumbar spinal stenosis, even in high-risk patients with multilevel stenosis. Ferritin: a novel mechanism for delivery of iron to the brain and other organs. It is assumed that cryopreservation without cryoprotectant removes all viable donor cells. The reliance on epidemiologic risk factors for the initiation of empiric antifungal therapy therefore provides the best method for early appropriate therapy. We conclude that methods combining advances in these 4 categories of required effort with new genomic technologies will result in biophysically motivated dynamic genome-wide regulatory network models for several of the best-studied organisms and cell types. The left atrial appendage (LAA) function was evaluated in patients with severe rheumatic mitral regurgitation, having sinus rhythm or atrial fibrillation, by standard and tissue Doppler echocardiographic examinations. Dq-r personality traits predict mortality by age 75 years, accounting, in part, for Dq-r mortality.

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To investigate potentialities of a novel biochemical test assessing oxidative resistance of plasma as a marker of ischemic damage to the myocardium and to study this marker correlation with high-performance ECG parameters reflecting electrophysiological remodeling of the myocardium in patients with ischemic heart disease (IHD). Studies funded by industry could be favoring the efficiency profile of their products. Each subject completed a written and video-assisted questionnaire and underwent bronchial challenge and skin prick testing. The ERICA Integrated Approach and its associated tool and databases provide a method by which the likely impact of radioactive discharges on the environment can be evaluated, see Fig. We describe a patient who presented with multiple subcutaneous lipomas, mild macrocephaly, and an extradural spinal hemangioma.

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The pathogenesis of coeliac disease (CD) and of dermatitis herpetiformis (DH) is strongly associated with production of autoantibodies, defined by indirect immunohistology. However, melatonin injected immediately after extinction training was ineffective on extinction learning. To help synthesize these data and make them available to the scientific community, we developed a web-accessible database. The main purposes of this study were (1) to assess the nutritional significance of eggs in the American diet and (2) to estimate the degree of association between egg consumption and serum cholesterol concentration. MCL-mediated infection increased transduction efficiency by 6.7-fold compared with the conventional method. While time- and concentration-dependent antitumour activity was observed against Colo 205 and Colo 201, no antitumour activity was detected against the other cell lines tested in an in vitro cytotoxicity assay. Recent studies confirm the importance of the hypothalamic-pituitary-adrenal axis for the development and course of mental disorders.

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Supraspinatus tendon repair into a bony trough in the rabbit: mechanical restoration and correlative imaging. An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells. A variable selection scheme, followed by contextualization of SNPs exhibiting independent associations within the haplotype structure of the gene, enhanced our ability to infer likely causal variants in this region with population-scale data. NVP(1) at a concentration of 6.6 microg/ml could arrest the cell cycle at stage G1 and inhibit the mRNA expression of cyclinB, cyclinD1 and cyclinE. In conclusion, these results may support the idea that methylated metabolites of As(2)O(3) contribute to the efficacy of arsenic in APL patients. The results were compared with a control group including 71 children with asthma treated with montelukast or cromones.

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Primary mediastinal clear cell sarcoma: a case report and review of the literature. After the operation, the patient was given chemotherapy with S-1 (120 mg/body on days 1-14) and CPT-11 (150 mg/body on day 1). The high-resolution transmission electron microscopy and electron diffraction studies reveal superlattice structure in CoSi nanowires with twice the lattice parameter of simple cubic CoSi lattice. pWU11-C8/119S/HB101 can be used as an easy, low cost expression system on a large scale. This paper investigates the conscious status of both the knowledge that an item is legal (judgment knowledge) and the knowledge of why it is legal (structural knowledge) in sequence learning. Patients have been surveyed between 12 and 18 months postoperatively. Furthermore, the transgenic rats develop severe sodium dependent hypertension. Intramuscular glutamine concentrations have been correlated to muscle protein synthesis. The current profile of persistent cloaca and cloacal exstrophy in Japan: the results of a nationwide survey in 2014 and a review of the literature. The nematode Caenorhabditis elegans is a simple metazoan animal that is widely used as a model to understand the genetic control of development.

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As expected prometrium 200 mg prezzo , individuals with social phobia provided self-ratings that were significantly more negative than controls across all dimensions. The method generates high concentrations of thermostable, uniform silver nanoparticulates that may have applications as catalysts. Time-resolved crystallographic experiments show that photodissociated carbon monoxide (CO) docks within 5 ns at the distal pocket B site and at more remote Xe4 and Xe2 cavities. The clear patient advantage of functional continence has pushed this procedure to the forefront in treating both UC and FAP. During a mean follow-up of 9.7 weeks, adequate oral intake was maintained in 38/39 cases. Adverse experiences were similar in all three treatment groups except that superficial thrombophlebitis was more frequent in the lubeluzole 10-mg group.

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Workflow technologies aim to assist scientists and domain experts in the design of complex, long running, data and computing intensive experiments that involve many data processing and analysis tasks with the objective of generating new knowledge or formulate new hypothesis. Spatially-localized bench-top X-ray scattering reveals tissue-specific microfibril orientation in Moso bamboo. Intraperitoneal injection of either 4 ml saline or zymosan suspension (0.50 mg/g body weight). When young adults are admitted to general hospitals they should receive special attention due to their suicidal potential. Since positive selection is likely due in part to a protective host immune response, the findings may have important implications for vaccine design and vaccination strategies. The sample consisted of 29 cystic fibrosis patients, characterized based on anthropometric, genetic and bacterial colonization data. To compare 2-year outcomes (mortality, mortality/myocardial infarction (MI), target vessel PCI (TVPCI), and target lesion PCI (TLPCI)) for patients receiving EES and ZES. The primary concern related to patient independence among persons with MS, regardless of their status, is loss of mobility.

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Assessments of psychological wellbeing showed greater dissociative symptoms in frequent users and a dose-response effect on delusional symptoms, with frequent users scoring higher than infrequent, abstinent users and non-users, respectively. Drilled hole defects in mouse femur as models of intramembranous cortical and cancellous bone regeneration. PtF6(2-) dianion and its detachment spectrum: a fully relativistic study. Reoperations occur frequently after initial lumpectomy for breast cancer. Patient characteristics that are associated with these subgroups can be used to identify patients who are at greater risk for multiple co-occurring symptoms and diminished QoL, so that these patients what drug class is zyvox can be offered appropriate symptom management interventions.

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2,4-Dichloro-1-nitrobenzene exerts carcinogenicities in both rats and mice by two years feeding. This scale-up evaluation demonstrates that the acid-assisted IL deconstruction technology can be effectively scaled up to larger operations and the current study established the baseline of scaling parameters for this process. New approaches for medicinal applications of bioinorganic chemistry. The study of mechanomyographic (MMG) signals during dynamic contraction requires a criterion to select the cut-off frequency of the filter utilized to separate the low frequency (L.F) component (basically due to gross movement of the muscle or of the body) and the high frequency (HF) component (related with the vibration of the muscle fibers during contraction). This investigation reports some of these distinguishing characteristics including enhanced ability for pseudohyphal switching upon nitrogen limitation and increased resistance to acidic pH. Importantly, IL-10-Tg mice that received interphotoreceptor retinoid-binding protein-specific uveitogenic T cells from wild-type donors were protected from EAU.

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