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Antram (Tramadol)

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Antram is a narcotic-like pain relieving oral medicine that is used as a treatment for moderate to severe pain in adults. This medication must be prescribed by a doctor and is available by prescription only.

Other names for this medication:
Acuvin, Avdol, Axedol, Bolodol, Bramadol, Eltram, Euphodol, Ivydol, Kevtram, Ondol, Pacadon, Paxmax, Pentazen, Radol, Ramax, Rybix, Sayodol, Servodol, Simol, Standol, Supridol, Tradol, Tramacip, Transic, Tranzat, Tridol, Ultrax, Ultrazac, Victadol, Zytram

Similar Products:
Glucophage, Detrol, Dramamine, Noroxin, Xanax

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Antram: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Antram is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Antram dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Fexofenadine/pseudoephedrine dosage information

Side effects

The most common side effects associated with Antram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Evaluation of an endoscopically assisted gastropexy technique in dogs. The laryngeal mask airway has been used increasingly in clinics but is seldom applied in anesthesia for oral surgery, as the mask occupies the middle of the mouth and tends to obstruct the surgical field. Plasmids pCMV-HA-hSav1 and/or pcDNA/4TO-Flag-Mst1 were transfected into HeLa cells, and 36 hours later cisplatin (50 micromol/L) as a pro-apoptotic agent was added for 14 hours. Intact ions of Bis-GMA and its derivatives were generally observed by 7.87 eV LDPI-MS, consistent with the formation of ions with relatively little internal energy upon threshold single photon ionization. Development of a new catheter prototype for laser thrombolysis under guidance of optical coherence tomography (OCT): validation of feasibility and efficacy in a preclinical model. It is not well established whether the increased number of leukocytes in the seminal fluid impairs the outcomes of assisted reproductive technology (ART). cholerae culture supernatants and shown to contain a 45-kDa polypeptide which bound anti-HA/P antibodies and which comigrated with HA/P in sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

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Mammography and ultrasonography indicated probable breast cancer. Local delivery of granulocyte colony stimulating factor-mobilized CD34-positive progenitor cells using bioscaffold for modality of unhealing bone fracture. Chromosomal abnormalities and reproductive outcome in Malaysian couples with miscarriages. This article provides such a review and emphasizes general principles rather than specific embodiments, which are very much at a nascent stage. Evaluation of the temporal variations of air quality in Taipei City, Taiwan, from 1994 to 2003. Mitochondrial transmembrane potential and uncoupling were also investigated, as well as ATP synthesis flux and ATP content. Hilar and mediastinal nodal regions were contoured on planning CT.

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HLA studies were performed using polymerase chain reaction sequence-specific oligonucleotide (PCR-SSO) genotyping methods in 91 patients with PsA and 80 with psoriasis and 75 controls. Study of the motion artefacts of skin-mounted inertial sensors under different attachment conditions. The decline of parasitaemia was slower and persistence or development of gametocytes was significantly higher and longer at day 3, 7 and 14 in the DP group but after 28 days no difference could be observed between both treatment arms. All patients had a significant improvement in their breast size and shape postoperatively and their breasts were soft and natural in appearance and feel. Metabolic, inflammatory, and microvascular determinants of white matter disease and cognitive decline.

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In separate cohorts of rabbits, single-unit recordings showed that medium spiny neurons from regions shown to be critical by lesions display strong responses to the CS, especially in the initial days of training before acquisition. Prediction of Resistance to Intravenous Immunoglobulin in Children With Kawasaki Disease. This treatment is repeated weekly at our outpatient clinic as long as possible. IgM antibodies to P1 cytoadhesin of Mycoplasma pneumoniae are part of the natural antibody repertoire expressed early in life. In vivo, laminin is primarily concentrated at the basolateral surface of pneumocytes where they rest on the basement membrane, which is composed primarily of laminin and collagen. Storage of whole blood samples at -80 degrees C is good for at least one year. Multifocal electroretinogram (ERG) and full-field ERG techniques were used to assess the effects of diabetic retinopathy and CSME on macular, paramacular, and peripheral retinal function. The mechanism of this inhibition seems to be through an action of SA on expression of HIF-1 and its downstream targets. Simultaneous overexpression of these genes is significantly associated with their loss of expression during development of hepatocellular carcinoma. This manuscript discusses each point to stimulate questions for future investigation.

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Our data suggest that both 10-week diet-plus-exercise and exercise-only therapeutic lifestyle programs are effective for improving anthropometric indices, insulin sensitivity, ultrasound findings and physical fitness in ultrasound-diagnosed NAFLD patients. The effects of frying and microwave cooking on generation of heterocyclic amines (HAs) in chicken legs with skin and without skin were studied. Obese patients with chronic inflammation in white adipose tissue (WAT) have an increased risk of developing non-alcoholic steatohepatitis (NASH). Tibolone: example of qualitative and quantitative assessments of the mammary gland. No defect occurs at the level of Myog promoter DNA methylation in any of the clones. DFT calculations carried out on model complexes show that for all the studied compounds the removal of the first two electrons corresponds to the oxidation processes of the iron centres in the weakly coupled ferrocenyl termini. Nearly all patients with major depression wanted treatment for this disorder, and more than 85 percent of patients with panic disorder, posttraumatic stress disorder, and generalized anxiety disorder indicated that the symptoms of these disorders were a reason for seeking treatment. Conversely, reproductive tissues such as flowers and developing seeds showed constitutive expression of LEA4, which was up-regulated in flowers under salt stress. Those with depressive symptoms were further evaluated using the fourth revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) Diagnostic Criteria for Depression, and depression severity was assessed using the 17-item Hamilton Depression Rating Scale for Depression (HAM-D).

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Lastly, signals generated by the retrograde messenger, nitric oxide- (NO-) are critical for the synaptic modulation since the PACAP-induced increases in spontaneous EPSC frequency, amplitude and quantal content were mimicked by NO donor and absent after inhibiting NO synthase (NOS). Surface mobility of postsynaptic AMPARs tunes synaptic transmission. History, physical examination, laboratory testing, and abdominal ultrasound support a diagnosis. MPR appears to be the most accurate quantitative index to detect anatomical and hemodynamically significant CAD. Although incredibly useful to treat disorders like depression, schizophrenia, epilepsy, or mental retardation, these drugs display many side effects. This pilot study aimed to classify clinical treatment changes implemented following e-consult to a pharmacist-run UDT service and analyze factors limiting pharmacist intervention postconsultation. The tight control of transcription and the potential to regulate gene activities quantitatively over wide ranges will open up new approaches in the study of gene function in vivo and controlled expression of heterologous genes. Partial Splenectomy is Superior to Total Splenectomy for Selected Patients with Hemangiomas or Cysts.

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An extended-release formulation of cyclobenzaprine (CER) has been developed to provide effective muscle spasm relief with once-daily dosing. Few examples of micropreparative peptide separations are shown and capabilities of CE and CEC techniques to provide important physicochemical characteristics of peptides are demonstrated. Significant differences in thyroid dysfunction were found between the regions with a minor difference in iodine excretion. The aim of this study was to investigate changes in the spectral characteristics of ventricular fibrillation in zones with radiofrequency lesions. Intensive care is a specialized branch of medicine dealing with the diagnosis, management, and follow up of critically ill or critically injured patients. A discrete choice survey was conducted with volunteers recruited from the general public. We have previously shown that high-grade chondrosarcomas express unspecified members of the Melanoma Antigen (MAGE) gene family. Behaviour and dynamics of di-ammonium phosphate in bauxite processing residue sand in Western Australia--II.

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We detected a BRAF mutation (V600E) in only one papillary renal cell carcinoma case. With the development of therapeutic agents that require repeated administration comes a need for new strategies to improve safety and maximize efficacy. The Silent Cerebral Infarct Multicenter Transfusion (SIT) Trial is a multi-institutional intervention trial in which children with silent cerebral infarcts are randomized to receive either blood transfusion therapy or observation (standard care) for 36 months. A wide range of responses were observed, and interneurons could be classified into three broad groups that received excitatory and inhibitory or principally inhibitory or excitatory synaptic inputs from the FeCO. It has been hypothesised that n3 fatty acids and other components of shark liver oil may exert anti-carcinogenic effects. Propoxycaine.HCl increased the bulk lateral and rotational mobilities, and annular lipid fluidity in SPMVs lipid bilayers, and had a greater fluidizing effect on the inner monolayer than that of the outer monolayer. Inhibition of Parp-1 activity (by 3-AB) reduced histone 3 lysine 9 acetylation and blocked Parp-1 binding to the BRCA2 promoter.

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Another common manifestation of systemic inflammation is behavioral depression. Management outcomes for ruptured and unruptured aneurysms in the elderly. Here we describe molecular events that occur during the onset of chorioallantoic morphogenesis in mice in vivo, and in placental explant and whole conceptus cultures in vitro. Our results depict the following changes: (1) Serum ACTH and CORT levels were increased by stress and CORT levels were higher in female rats than males. Four of the materials were found to be suited for the construction of NMR probes, housing of RF coils, and holders for in vivo experiments. (3) The children who reported a higher level of parent-child communication also reported a higher level of life and school satisfaction and happiness, and no differences in loneliness were found by levels of parent-child communication. This report shows that beta-catenin can regulate the level and transcriptional activity of the Notch1 and Notch1 intracellular domain (NICD). (32)P colloid radiosynovectomy in treatment of chronic haemophilic synovitis: Iran experience. S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury.

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Although some conventional hydrogel soft lenses are able to achieve this criterion for either central or peripheral lens areas (depending on lens power), in general, no conventional hydrogel soft lenses meet both the central and peripheral thresholds. Dense gene physical maps of the non-model species Drosophila subobscura. This case highlights that generalized convulsion is a very rare, but serious adverse effect of tranexamic deltasone tabs acid. There was differential medical service use amongst the displaced population, determined by their health insurance coverage and economic position. The aim of this study was to explore associations between NSAID use and mortality in patients with inflammatory polyarthritis (IP). DTH was assessed using a kit which includes 7 recall antigens that most of the participants encountered during childhood immunization. Same day antiplatelet loading may be insufficient to achieve adequate platelet inhibition and should be avoided if clinically feasible. Statin, as HMG-CoA reductase inhibitor, prevents endothelial dysfunction in CVD. Injecting late instar larvae of the red flour beetle, Tribolium castaneum, with the bacterium, Escherichia coli, stimulated nodulation reactions and sPLA(2) activity in time- and dose-related manners.

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To investigate whether longitudinal sleep duration patterns during early childhood is a risk factor of overweight or obesity at school entry while controlling for a variety of obesogenic environmental factors. Only non-clustered sit genes were found in the genomes of other diatoms. Predicting High-Impact Pharmacological Targets by Integrating Transcriptome and Text-Mining Features. The nitrogen adsorption-desorption indicated that ZIF-8/PES beads had very high surface area which makes them suitable for adsorption applications. Our objective was to determine how child- and family-level factors and the medical home are associated with work loss for these families. Bacterial Signaling to the Nervous System through Toxins and Metabolites. Detecting ligands and dissecting nuclear receptor-signaling pathways using recombinant strains of the yeast Saccharomyces cerevisiae.

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Preservation of humidity and heat of respiratory gases in spontaneously breathing, tracheostomized patients. Losartan treatment was associated with a significant reduction of the bax-to-bcl-2 ratio and TNF-alpha expression after SBR compared to non-treated groups. The strategy of preparation of mono- and double-modified polyene macrolides was based on the use of intermediate hydrophobic N-Fmoc (9-fluorenylmethoxycarbonyl) derivatives that facilitated the procedures of isolation and purification of new compounds. With the use of computer image analysis methods, we detected differences in size distributions of vesicles in different exposure groups. Since spontaneous regression is known, only complex or larger cysts need surgical intervention, preferably by laparoscopy. Antenatal depression and male gender preference in Asian women in the UK. Incidence data were obtained from the population-based NRW diabetes register and regional socioeconomic data from official statistics. Moreover, with practice the movements of the controlled device - the cursor - became faster, smother, more precise and with a nearly symmetric speed profile. This study was designed to stimulate consideration of ultram 50 dosing this tumor. In this work, we show that synchronization of nonidentical dynamical units that are attractively coupled in a small-world network is strongly improved by just making phase-repulsive a tiny fraction of the couplings.

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Biodegradation of Rubine GFL by Galactomyces geotrichum MTCC 1360 and subsequent toxicological analysis by using cytotoxicity, genotoxicity and oxidative stress studies. The results implied that E13.5 RPCs might be a better choice for RGC replacement therapy, while E17.5 RPCs might be better for photoreceptor replacement therapy. Case reports of various congenital anomalies involving the eye and adnexae in Edo State, Nigeria seen over a 1-year period are presented. Incidence and risk factors for venous thromboembolic disease in podiatric surgery. The future excess fraction of occupational cancer among those exposed to carcinogens at work in Australia in 2012. Two of the three subjects displayed positive changes in use and movement of the affected hand in some tasks with Bilateral Isokinematic Training. As a representative example, we cloned the scFv gene from a hybridoma-producing mouse IgG against branched-chain keto acid zithromax 500mg dosage dehydrogenase complex-E2 (BCKD-E2) into an expression vector containing an in-frame phoA gene. Emerging Role of Corticosteroid-Binding Globulin in Glucocorticoid-Driven Metabolic Disorders. Atthese temperatures, the cellular morphology showedsignificant alteration and the growth was stronglyarrested. This non-blinded comparison indicates that FP is a more accurate insulin pre-filled pen than SS at three different insulin doses.

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It was found that all these lines, except RPMI 8226, produce FCRLA but may vary in the proportion of FCRLA-positive cells. Analysis of causes of death in patients hospitalized in the department of pneumonology. Computed tomography was performed to measure the area of visceral and subcutaneous adipose tissue (VAT and SAT). Percutaneous subclavian central venous catheterization in children and adolescents: success, complications and related factors. Affected homologous chromosome pairing and phosphorylation of testis specific histone, H2AX, in male meiosis under FKBP6 deficiency. cAMP/PKA-dependent increases in Ca Sparks, oscillations and SR Ca stores in retinal arteriolar myocytes after exposure to vasopressin.

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A chart review of 163 consecutive children 9 years of age or older admitted to National Jewish for difficult to control asthma was done. In vitro determination of phagocytosis and intracellular killing of Aspergillus species by mononuclear phagocytes. These results have implications for the evolutionary significance of global network topologies, which are known to be conserved across disparate complex systems. The FecXR and the FecXGr mutations, when present respectively in Rasa Aragonesa ewes at the heterozygous state and in Grivette ewes at the homozygous state, were associated with a twofold increase in ovulation rate. Biofilm production by Candida species and inadequate antifungal therapy as predictors of mortality for patients with candidemia. The overall rate of mitochondrial oxygen consumption increased at high P(O2). It was found that the spin helicity of the cycloidal spin order is always fixed to the lattice, therefore the magnetic propagation vector k determines the sign of electric polarization in Ba2CuGe2O7.

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Rhesus glycoprotein p2 (Rhp2) is a novel member of the Rh family of ammonia transporters highly expressed in shark kidney. Regenerated adsorbents showed larger surface area and micropore width than the original samples, indicating that no pore blockage was produced. The histopathological specimens of 65 patients who underwent PKRP and TURP were examined retrospectively. Metastatic melanoma to the common bile duct is very rare with only 18 cases reported so far. The number of novel giant viruses identified and characterized from the recently proposed order Megavirales has increased in recent years and new questions have been raised regarding viral diversity and evolution.

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Emilin1 deficiency causes structural and functional defects of lymphatic vasculature. At where to buy xenical in perth birth PACAP-immunoreactive nerve fibres and a few cells were present in the Purkinje cell layer, but already at postnatal day 7 an adult PACAP immunostaining pattern was found. When tested with H35 rat hepatoma cells we showed that single cancer cells could grow into three-dimensional spheroids, demonstrating the utility of this method in understanding the role of anoikis in cancer. We show that the apoptosis of neuroendocrine cells increases in aged wild type mice, but not in HER2/neu ones. It is demonstrated that LTRS has sufficient sensitivity for real-time, nondestructive, and quantitative monitoring of biological processes, such as protein expression, in single living cells. Unusual sequestered disc fragments mimic spinal tumors and other space-occupying lesions due to a lack of discernible clinical features that can be used to differentiate these disc fragments from disc herniations and tumoral lesions.

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