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Anxicalm (Alprazolam)
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Anxicalm

Anxicalm is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Anxicalm, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Anxicalm is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alprocalm, Alsert, Alzam, Alzokam, Alzolite, Anzal, Anzocalm, Axizox, Azoslip, Calmtec, Emcalm, Exprex, Hipose, Manzolam, Prolam, Pronext, Prosanti, Richpram, Romipraz, Sertamax, Silam, Tancalm, Visram, Zocam, Zolax, Zolorest

Similar Products:
Zebeta, Thorazine, Risperdal, Amoxil, Lioresal, Effexor, Lexapro, Plaquenil, Ticlid, Clozaril

Also known as: Alprazolam

Description

{name} XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

{name} XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

{name} XR may also be used for other purposes not listed in this medication guide.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Anxicalm dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Anxicalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Anxicalm if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Anxicalm is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Anxicalm while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Anxicalm is not approved for use by anyone younger than 18 years old.

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A case report of a novel approach to treat scleral melts that may be seen in several clinical situations. The triplex can competitively inhibit the binding of transcription factors and, as a result, transcription can be inhibited. The evolution followed on a period from 2 to 9 years, revealed the resorbtion of the hemorrhages between 3 and 6 months, the reversible visual acuity in the cases without macular implication, and the absence of recidiva or bilateralisation. To explore the role of Ser-21 phosphorylation on C/EBPalpha function during adipogenesis, we developed constructs in which Ser-21 was mutated to alanine (S21A) to model dephosphorylation. We show here that an HMR locus with a defective silencer can be silenced by anchoring the locus to the nuclear periphery.

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Trap catch was consistently high in some locations and low in others. In parasitic organisms, TRG-encoded proteins are possible determinants of the specificity of host-parasite interactions. Tachykinins (TKs) are small peptides widely distributed in the central and peripheral nervous systems where they act as neurotransmitters. A retrospective chart review was conducted on 18 adult patients who underwent modified Nuss procedure in the age range of 18-31 years. Currently, the use of single-stage incubation in Europe has increased, because research has shown this system more precisely meets the developmental demands of the embryos. MRI also provides details about anatomic extent of the lesion, proximity to vital structures, and involvement of multiple tissue planes.

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Work in the United Kingdom within the VetCompass program utilizes routinely recorded clinical data with the addition of further standardized fields. Data on 1,098 residents were used to examine the relationship between facility policies as measured by domains of the Policy and Program Information Form and resident depressive symptoms and its factors as measured by the Cornell Scale for Depression in Dementia. Diffusion weighted imaging (DWI) studies in humans have shown that seniors exhibit reduced white matter integrity compared with young adults, with the most pronounced change occurring in frontal white matter. We performed separate studies using different types of samples to evaluate the utility of the Capillarys for (i) separating Hb S and other variants, and (ii) for performing the routine activity of our laboratory for 20 working days. The fusion kinetics and steady length of rods formed by smaller versus larger spheroids ( approximately 100 vs. A polymerase chain reaction-based approach was used to identify sequence variants of the human CYP3A4 gene. Moreover, it is unknown whether young neurons in the adult exhibit subregion-specific patterns of activation.

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PBMC collected from 15 artificially infected animals were incubated with different concentrations of total MmmSC antigen. These findings suggest an increased risk of UI associated with use of postmenopausal hormone therapy in younger postmenopausal women. We report a 39 years old woman with a 32 weeks pregnancy who sought emergency care due to hyperemesis. The fission yeast Hsk1p kinase is an essential activator of DNA replication. Multimers of the integral membrane TatA protein are thought to form the protein-conducting element of the Tat pathway. Chlorhexidine-silver sulfadiazine-impregnated central venous catheters: in vitro antibacterial activity and impact on bacterial adhesion.

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Presacral and intrathoracic extramedullary hematopoiesis: a case report. Time since menopause had a stronger predictive value for low BMD (osteopenia or osteoporosis) in the lumbar and hip areas than did serum FSH or estradiol levels. Schizophrenic patients are impaired in their biological response to stress by showing a blunted cortisol response to psychosocial stress. The purpose of this study was to assess the influence of identification of the location of the internal opening of anal fistula on the recurrence rate after surgical treatment in patients with primary transsphincteric anal fistulas. We describe a family in which 3/6 siblings had transient, relapsing neonatal diabetes. The mice were randomly divided into four groups: group A received normal saline, group B received DNR, group C received MNPs-Fe3O4, and group D received DNR-loaded MNPs-Fe3O4. This introduction includes a review of some of the current literature on the effects of maltreatment and prenatal alcohol exposure on child development, an explanation of why this topic is essential learning for communication professionals, prevalence figures for the occurrence of these effects, and a summarization of the articles that have been contributed by a cross section of researchers from various disciplines.

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Methadone patients fared as well as other opioid users in TC treatment. There was also no significant relationship between total particulate levels and pollen germination rates across all road types. Tedizolid was superior to vancomycin for clinical response at EOT and PTE. Regional level risk factors associated with the occurrence of African swine fever in West and East Africa. In comparison with the central regions of primary PTCs, the invasive fronts overexpressed TGF beta, NFkappaB and integrin pathway members, and regulators of small G proteins and CDC42. Relevant textbook chapters and personal experience have also supported the evaluation. mastectomy) and the need for additional local therapy, such as radiotherapy, are unclear. The MEK/ERK inhibitor PD98059 dramatically repressed HtrA3 induction. This interference is suppressed by increasing the concentration of either primer TP or phi29 DNA polymerase.

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Hand, foot and mouth disease is sporadically reported from India as a mild illness. SDH in asymptomatic term neonates after delivery is limited in size and location. The addition of a bioactive scaffold to the wound site improved the functional healing of the ACL after suture repair. Recent discoveries may help to reveal the molecular basis of the tumor suppressive action of this retinoic acid receptor subtype and provide new tools for its analysis and, possibly, therapeutic exploitation. Contrast-enhanced multiphase CT and dynamic gadolinium-enhanced MR have been validated in the literature as outstanding modalities for the evaluation of pancreatic pathology. Noninvasive assessment of coronary vasodilating capacity using freehand 3-dimensional echocardiography with rotational scanning. We compare single-level and hierarchical methods for estimation of the parameters of ex-Gaussian distributions. Arp2/3 complex-dependent actin networks constrain myosin II function in driving retrograde actin flow. These data suggest that ELF1 plays a similar role to LFY in flower development and that the basic mechanisms involved in flower initiation and development in Eucalyptus are similar to those in Arabidopsis.

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Effect of polyelectrolytes and quaternary ammonium compounds on the anaerobic biological treatment of poultry processing wastewater. As for the contiguous guanines (a guanine run), we found that the IP in the gas phase significantly decreases with the increasing number of nucleotide pairs of the guanine run, whereas the IP in water (OP, oxidation potential) only slightly does. Nonlinear optical switching properties in the furylfulgide aberchrome 540-dihydrobenzofuran derivative pair of photochromic materials. Direct bonding between the newly formed bone and HAp-coated Ti was observed with the O-, N-, and P-surfaces. Median survival time and RCC-specific survival rates were evaluated. Nr1d1, an important circadian pathway regulatory gene, is suppressed by cigarette smoke in murine lungs. Among them, we detected strong induction and secretion of CEACAM5 protein. The goal of this study was to evaluate the effect of CYP3A4, a gene associated with the oxidative deactivation of testosterone, on the clinical presentation of prostate cancers. Moreover, pertussis toxin, which inhibits FGF-2-stimulated endothelial cell movement, also partially suppressed Lp(a)-induced HUVEC migration.

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Minimal invasiveness and high efficiency characterise the implantation of metallic stents in the treatment of malignant biliary or esophageal obstruction and vena cava compression syndrome. Most series of hemispherectomies include mainly pediatric patients. Teaching methods included lectures, discussions, demonstrations, and self-directed learning. The effect of metformin on haemostasis may play a role in the prevention of atherosclerosis-related disorders and acute vascular events in this pre-diabetic state. This study examined cognitive dysfunction in patients with ESLD using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).

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Previous studies have shown that untreated patients with acute schizophrenia present with reduced heart rate variability and complexity as well as increased QT variability. They constitute a reservoir of self-sustaining cells with the ability to maintain the tumor growth. Arrhythmia classification with reduced features by linear discriminant analysis. Species identification and authentication in meat products are important subjects for ensuring the health of consumers. Data matrices used in the analyses included 951 base pairs (bp) of aligned sequences for 28S, 465 bp for 16S, and 658 bp (219 amino acids) for COI. We now report loss of E-cadherin expression as well as a marked reduction of beta- and alpha-catenin expression in transdifferentiated MDCK-C7 cells stably expressing caMEK1 (C7caMEK1) compared with epithelial mock-transfected MDCK-C7 (C7Mock1) cells. Diagnosis of nosocomial pneumonia: noninvasive but not undirected. It is shown that, to a certain extent, eliminating the unimportant synaptic couplings does not degrade the network performance.

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High-methionine diet significantly increased serum homocysteine levels, decreased hepatic CBS activity, and down-regulated paraoxonase-1 mRNA and its activity. Clinical signs were rapidly progressive, cordarone 200 mg tabletten despite empiric therapy with anti-inflammatory medications, resulting in the death of the animal. In this work, a total of 303 unrelated individuals (203 males and 100 females) in the Chinese Han population were analyzed with Mentype Argus X-8 PCR amplification kit (DXS10135-DXS8378, DXS7132-DXS10074, HPRTB-DXS10101, and DXS10134-DXS7423). Ligament of Marshall: why it is important for atrial fibrillation ablation. Although early analysis based on multilocus enzyme electrophoresis (MLEE) described the population structure of this species as clonal, more recent reports have suggested that recombination also contributes to shaping variation across its genome. Multicenter randomized control trial on safety of domestic idarubicin for acute leukemia. Cyclooxygenase (COX)-derived prostanoids (PGs) are involved in blood pressure homeostasis. We retrospectively analyzed cause of liver disease in all patients with cryptogenic intrahepatic portal hypertension who underwent liver biopsies between June 2005 to June 2007 in our center. Autonomic nervous systemic imbalance, as reflected by altered heart rate variability, is associated with adverse clinical sequelae.

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The asymmetry indexes AT and GC skews on P4FD are much higher than those on P123, suggesting the existence of asymmetrical directional mutation pressure. Two such noninvasive modalities are navigated transcranial magnetic stimulation ultram urine drug screen (TMS) and magnetoencephalography (MEG) imaging. Catalytic NH3 Synthesis using N2 /H2 at Molecular Transition Metal Complexes: Concepts for Lead Structure Determination using Computational Chemistry. No statistical significant differences were detected in either group between the total BMD values obtained for the femur and lumbar spine before and after treatment. Also discussed are the key processes determining intramembranous bone growth, namely osteoblastogenesis and osteoclastogenesis. Creation of a dynamic digital phantom and its application to a kinetic analysis. With respect to the annular wall, the posterior region is most susceptible to failure in the presence of high nuclear pressure, even when loaded in the neutral position. New England Society of Disaster Medicine holds annual meeting at Brown - Preparing for epidemics and natural disasters. Previous reports defined medialization in relation to the neutral position of the femoral component, but omitted to compare it to the anatomical position of the trochlea.

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Attempted infection induced the formation of papillae, cell wall thickening, production of reactive oxygen species, callose deposition and accumulation of phenolic compounds in plant cell walls. Serum CAIX levels also correlate with the desloratadine brand name uk tumor size in CCRCC patients. In cases where an ischemic contracture results in pain, disability or soft tissue compromise, surgical intervention is indicated. Provider judgments of patients in pain: seeking symptom certainty. It is concluded that protein secretion in Sulfolobus is a limited process, and it is suggested that the S-layer may act as a barrier for the free diffusion of folded proteins into the medium. Contractility and intestinal epithelial ion transport were assessed in isolated ileal segments. In this article, we review the current knowledge about the contribution of DNA repair to drug resistance in human leukaemia. Prognostic utility of impedance cardiography measurements in elderly hemodialysis patients with coronary artery disease.

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Nursing students who are employed to deal with swine flu must get honorary contracts from their employers and have the same access to antivirals and vaccines as other staff, the Department of Health (DH) said last week. Collaborative members revised curricula, developed new teaching strategies, and established the foundation for future faculty development efforts to advance teaching of quality and safety concepts in nursing education. Intercostals were useful for finger flexion and the contralateral C7 root was useful for finger extension. To design a diagrammatic record of lacrimal disease using easily interpretable symbols. Transitional Dynamic Analysis (TDA) is a new method to detect these changes in local protein flexibility between different conformations arising from, for example, ligand binding. Finally, by comparing the two sets of periods and phases, the period change and the phase shift by stimuli were estimated to extract the candidate genes related to the master clock, by mapping the period change and the phase shift on a two-dimensional space, a period-phase map (PPM). Non-small cell lung cancer (NSCLC) is a serious life-threatening malignancy. Bone mineral density according to age, bone age, and pubertal stages in korean children and adolescents. The study demonstrates that it is possible to stimulate bone resorptive and formative cells with thyroid hormones in both types of ADO. Comparative effects of N-acetyl-L-cysteine and ramipril on arterial hypertension, insulin resistance, and oxidative stress in chronically glucose-fed rats.

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