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Aprical (Nifedipine)

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Aprical is a drug that performs by relaxing the muscles inside the heart and blood vessels in order to enable easier blood flow. This enables the heart to have an easier time pumping blood. The active ingredient is nifedipine and it a part of a class of drugs called calcium channel blockers. The primary use of this medication is to help stop chest pain (angina) and help treat high blood pressure problems (hypertension). In addition to this it can also be used in order to heighten the supply of oxygen and blood to the heart and help with a specific blood circulation condition called Raynaud’s phenomenon.

Other names for this medication:
Adipine, Calchan, Cardifen, Chronadalate, Coracten, Cordaflex, Cordilat, Corotrend, Depin, Hypan, Jutadilat, Milfadin, Nedipin, Nidipine, Nifcal, Nifecap, Nifecard, Nifecor, Nifed, Nifedel, Nifedicor, Nifedipin, Nifedipinum, Nifezzard, Nilol, Noviken, Nycopin, Oxcord, Pabalat, Pressolat, Tredalat, Xepalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Aprical PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Aprical and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Aprical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Identification by gas chromatography/mass spectrometry of long-chain fatty acids and alcohols from hamster meibomian glands using picolinyl and nicotinate derivatives. Congenital malformations induced by ethyl-urethan in mouse embryos. The median serum xylose was low and there was delayed urinary xylose excretion. Chromosome studies in patients with T-CLL chronic lymphocytic leukemia and expansions of granular lymphocytes. Adjustment to disease and handicap in the medical rehabilitation of chronically ill or handicapped persons. Predictive value of discriminant analysis of monocyte ultrastructure in malignant lymphoma. Studies on the m.frontalis, auricularis superior and auricularis anterior of primates including man. Twenty-three had DSA as part of a hypertensive screening workup for renovascular disease. Axonal sub-populations in the central nervous system demonstrated using monoclonal antibodies against alpha-tubulin. Histologically, there was minimal evidence of thermal damage to the surrounding tissue.

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The fourth genus in the Orthomyxoviridae: sequence analyses of two Thogoto virus polymerase proteins and comparison with influenza viruses. To assess General Practice (GP) description and management of upper respiratory tract infections (URTI), including conditions under which they prescribe antibiotics. Relationship of toxoplasma infections to other diseases in dogs. Here we demonstrate that serum leptin levels are modulated during normal rat pregnancy with a 1.8-fold increase during pregnancy followed by a decrease just before parturition. Evolution of reduced pre-adult viability and larval growth rate in laboratory populations of Drosophila melanogaster selected for shorter development time.

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