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Asoprol (Metoprolol)
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Asoprol

Asoprol is an inexpensive drug used to treat high blood pressure and prevent chest pain. It is also used after a heart attack to prevent an additional heart attack from occurring. This drug is more popular than comparable drugs. It is available in brand and generic versions.

Other names for this medication:
Actiblok, Actocard, Asoprol, Betaloc, Betaone, Blumeta, Cadmet, Dutoprol, Intramet, Macsart, Mepol, Metapro, Metin, Metocare, Metofin, Metolar, Metolex, Metomac, Metoprolol, Metozest, Metpure, Metscore, Metzok, Nexovas, Powermet, Sitelol, Supermet, Telidin, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Also known as: Metoprolol

Description

Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. A lower blood pressure can reduce the risk of strokes and heart attacks.

Metoprolol is also used to treat severe chest pain (angina) and lowers the risk of repeated heart attacks. It is given to people who have already had a heart attack. In addition, metoprolol is used to treat patients with heart failure.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain metoprolol. It may not be specific to Asoprol. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should first check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, strokes, or kidney disease.

Swallow the extended-release capsule and tablet whole. Do not crush, break, or chew them.

If you cannot swallow the extended-release capsule:

You may open it and sprinkle the contents over a small amount (teaspoonful) of soft food (including applesauce, pudding, or yogurt). Swallow the mixture within 60 minutes. Do not store for later use. You may also use a nasogastric tube to give the medicine. Mix the contents of the opened capsule with water into a syringe. Gently shake the mixture for about 10 seconds, then flush it through the tube. Rinse the tube with water until all of the medicine is washed out.

Take the tablet or extended-release tablet with a meal or just after you eat. You may break the extended-release tablet into two pieces, but swallow the two pieces whole and do not crush or chew them.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute heart attack or heart failure: For oral dosage form (extended-release capsules): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. In patients with severe heart failure, the starting dose is 12.5 mg once a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 50 milligrams (mg) every 6 hours for 2 days. Then, 100 mg 2 times a day. The medicine will be started in the hospital. Children—Use and dose must be determined by your doctor. For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given in two divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight once a day. The first dose should not be more than 50 mg once a day. Your doctor may adjust your dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight per day, given as a single dose. The first dose should not be more than 50 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given as a single dose or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 450 mg per day. Children—Use and dose must be determined by your doctor. .

Overdose

If you overdose Asoprol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Asoprol overdosage: fainting, difficulty, breathing or swallowing, swelling of the hands, feet, ankles, or lower legs, lightheadedness.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Asoprol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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More attention on forms of fertilisers more suitable to highly alkaline, microbially inert soil conditions appears to be warranted. The mechanism whereby the genetic variants exert their effects on ischemic stroke remains to be further elucidated. Here we present a more global view of the induced thermostability and show that the A35 V mutation affects the underlying structural rigidity of the whole protein via a number of long-range, non-local interactions. Prospective, randomized trials of serum protein manipulation are needed to establish whether there is a cause-effect relationship to this association. Frequency statistics and cluster analysis have been carried out to elucidate the medication rules and commonly used Chinese medicinal materials (CMM) for prevention and treatment of PD during the middle period. First 100 patients, with injuries of spinal cord on different levels, were included in this prospective clinical study. Movement of the brain caused by this increase in volume will cause an absorption change of approximately half this magnitude, but does not affect the photon arrival time at 4-cm spacing. Effects of Hippocampal LIMK Inhibition on Memory Acquisition, Consolidation, Retrieval, Reconsolidation, and Extinction. However, this hypothesis has not been rigorously tested hitherto. Different target groups with individual needs and precognition are addressed.

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The aim of this study was to demonstrate the advantages and efficacy of an absorbable haemostatic sponge for use in coloproctology during surgery for the most frequent pathologies of the anal canal and perineal region. The correlation coefficients between the total volume of fat pixels and the amount of abdominal fat determined in the coronal plane by MRI were 0.85 and 0.95 in the male and female sex, respectively. Cellular levels of diaminopropane, putrescine and cadaverine, and decarboxylase activities to produce these diamines in six species (16 strains) of Haemophilus and four species (5 strains) of Actinobacillus belonging to the family Pasteurellaceae of the gamma subclass of the class Proteobacteria, were determined by high performance liquid chromatography (HPLC). We aimed to determine the influence of monitor/camera position on the laparoscopic performance of surgeons of varying skill levels. Articles from each of these journals were evaluated according to the previously established 10-point quality criteria for reporting and to test the MLR model assumptions. The toxic effects of several nitro-PAHs are more pronounced than those of PAHs. We report a very rare case of a 79 -year- old man, known to be hepatitis C virus carrier with a metastatic tumor in abdominal wall caused by seeding of tumor after three years following a percutaneous biopsy procedure. The full text of the studies and their methodological quality were analyzed. However, the neurotoxic actions of glutamate were unaffected by NRG-1.

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Simple reaction conditions accompanied by good yields of indolyl-nitroalkanes are the merits of this methodology. Principal component analysis (PCA) was performed on the MSC-treated spectra in the regions 6300-5650 cm(-1), 4850-4300 cm(-1), and 3500-2880 cm(-1) to detect the end-point of the fermentation as an example of process monitoring. Chromatin can adopt a decondensed state linked to gene transcription (euchromatin) and a condensed state linked to transcriptional repression (heterochromatin). Rhabdomyosarcoma (RMS) is a pediatric malignacy of muscle with myogenic regulatory transcription factors MYOD and MYF5 being expressed in this disease. To test this hypothesis, we introduced the soybean lectin gene Le1 either behind its own promoter or behind the cauliflower mosaic virus 35S promoter into Lotus corniculatus, which is nodulated by R. We sought to evaluate the effects of carbonated drink intake on human carbonyl stress. These aspects, although rare, may be the earliest signs of the disease and sometimes its only manifestations. Intl1 includes the four conserved amino acids that are characteristic of members of the integrase family, and Intl1 proteins with single amino acid substitutions at each of these positions had substantially reduced catalytic activity, consistent with this classification.

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The lack of potent, selective, brain penetrant Y(2) receptor antagonists has hampered in vivo functional studies of this receptor. Acclimatory responses of Arabidopsis to fluctuating light environment: comparison of different sunfleck regimes and accessions. We show that RIP1 is the primary cellular target responsible for the antinecroptosis activity of necrostatin-1. Accuracy of ICD-9-CM coding for the identification of patients with acute ischemic stroke: effect of modifier codes. Our goal was to evaluate whether the presence of ischemic lesions of varying ages identified by DWI and apparent diffusion coefficient (ADC) suggests a higher risk of future ischemic events. Time constraints, however, can make adhering to universal precautions, including proper hand washing, difficult. Average ARD rates were consistently higher from 2000 to 2006 than from 1995 to 1999.

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Readmission rates at 7 days and at 1 year were estimated using the Kaplan-Meier method. Examination of platelet function in whole blood under dynamic flow conditions with the cone and plate(let) analyzer: effect of erythrocytosis and thrombocytosis. At 6 and 12 months after delivery, elderly edentulous males and females wearing mandibular implant overdentures were significantly more satisfied than those wearing conventional dentures. This province has experimented a sharp reduction of the most fertile soils, located on the Henares valley, due to the action of new models of local and regional development. We used this approach to study methylation of the CDKN2B (p15) cell cycle progression inhibitor gene which is inactivated by DNA methylation in haematological malignancies of the myeloid lineage uroxatral drug interactions . We provide evidence that solvent acidity modifies the behavior of the transient intermediates. The Relationship Between Body Image and Sexual Function in Middle-Aged Women. We have examined the differential roles of TR isoforms in mediating T3-dependent repression of the human thyrotropin (TSH)-alpha subunit gene promoter in vitro, and have assessed TR binding characteristics using gel mobility shift assays. In turn, isolation of these cells has allowed therapeutic stem cell transplantation protocols to be developed, that capitalise on their prodigious self renewal and proliferative capabilities. We consider all 35 five- and six-member rings containing isomers of small fullerenes, C20, C24, C26, C28, C30, C32, C34, and C36, as first part of a larger effort to catalog CC distance distributions, valence CCC angle distributions, electronic densities of states (DOSs), vibrational densities of states (VDOSs), and infrared (IR) and Raman spectra for fullerenes C20-C180.

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20 years have passed since the discovery of the hepatitis C virus (HCV), and yet therapeutic options remain limited. It appears that selective forces shape how local patterns of coexpression change over time but do not control the global topology of C. Airtraq laryngoscope: a solution for difficult laryngeal exposure in phonomicrosurgery. The number of binding sites, n was noticed to be almost equal to unity thereby indicating the presence of a single class of binding site for FLX on HSA. It was shown that in young rats under stress vasopressin (VP) is released into the portal circulation and probably in this way stimulates ACTH and enhances secretion of corticosterone in the adrenal cortex. As a way to overcome this limitation and to find a simple way to screen for protein changes at cultured synapses, we have produced and characterized two dimensional electrophoresis (2DE) maps of the synaptic proteome of CA3-CA1 hippocampal neurons in culture. Taura syndrome virus (TSV) is one of the major pathogens causing mortality in the whiteleg shrimp, Litopenaeus vannamei. Similar studies were done in cortical slices from these rats and in cultured cortical neurons exposed to ammonia.

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Progress in multifunctional nanomaterials for tumor therapy mostly depends on the development of tumor-targeting delivery strategies. Until then, we advocate standard low dose radiotherapy preceding resection in all patients with lesions suggestive of a proximal bile duct tumour who have undergone biliary drainage. Postoperatively, the patient developed ischaemia what is the highest dose of robaxin of the limbs which was confirmed by angiography. Collagen-platelet composite enhances biomechanical and histologic healing of the porcine anterior cruciate ligament. Protection of this surviving species would conserve an ancient mammalian family.

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Iron source sensing is mediated by distinct transcriptional activators that are responsive to the cognate iron source acting as the inducer. Transport spectroscopy of single phosphorus donors in a silicon nanoscale transistor. Functional outcome following quadriceps tendon lengthening in congenital dislocation of the knee, with special reference to extensor weakness. Pilocarpine and timolol were not significantly different from each other and both produced a more marked pressure reduction than betaxolol. Subjects belonging to different age groups had different reflex thresholds. Remarkably, several substitutions (E334A, V336R, G340S, and T342P) increased the steroid binding affinities of human CBG even before elastase cleavage, consistent with the concept that CBG normally toggles between a high affinity ligand binding state where the RCL is fully exposed and a lower affinity state in which the RCL is partly inserted into beta-sheet A.

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In cattle, the prognosis of brain abscess is unfavourable and treatment is therefore not recommended. Correlates of anti-hepatitis C positivity and use of harm reduction services among people who inject drugs in two cities in Croatia. Although it has long been known that kinematics of buccal expansion in feeding fishes are characterized by an anterior-to-posterior what drug is stronger xanax or ativan wave of expansion, this pattern has not been incorporated in most previous computational models of suction feeding. To evaluate the cardiovascular actions of kinins, we established a transgenic rat line harboring the human tissue kallikrein gene, TGR(hKLK1). Peripheral giant cell granuloma associated with dental implants: clinical case and literature review. Small but consistent deficits in the amblyopic eye of these observers were found, and shown to be limited to dotted-line targets composed of greater than seven dots (with performance being normal for targets of less than seven dots). The patient underwent salvage radiation therapy that resulted in a complete response, and is currently alive and disease free at 46 months after the onset of the combined chemotherapy. Immunohistochemical detection of some antigens located either in the nucleus, in the cytoplasm, or on the cytoplasmic membrane could be impaired by storage of paraffin slides as short a time as three months.

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Autotransplantation of epithelial cells in the pig via an aerosol vehicle. Theoretical and experimental comparison of constant inspired concentration and pulsed delivery in NO therapy. We tested whether exploratory behaviour in a novel environment predicts how free-living individual great tits (Parus major) react to a change in food supply. During rumination, oesophageal liquid retrograde flow is first driven by an early small rise in intragastric pressure preceding the peak pressure observed during straining. The initial application of this technique was the selection of particles that bound to human dendritic cells (DCs).

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A new anatomic model of the paranasal sinuses was developed by the Department of Anatomy at the University of Zurich. In the ABF, the edge slope is enhanced by transforming the histogram via a range filter with adaptive offset and width. This study examined whether genetic differences in the EGF predict differences in the self-reported level of activity temperament in adults. Dramatic changes in age distributions of prostate cancer incidence, mortality and hospitalizations altered age profiles of men with prostate cancer. Several important issues for the established association between tobacco smoking and upper aerodigestive tract (UADT) cancer risks include the associations with smoking by cancer subsite, by type of tobacco, and among never alcohol drinkers and the associations with involuntary smoking among nonsmokers. Characteristics of noise-canceling headphones to reduce the hearing hazard for MP3 users. The binocular acuities of zithromax medication older individuals can be inferred from measures of monocular acuity. The results of this study suggest that the effect of exercise on bone at an older age is different from that at other ages. We undertook new meta-analyses of existing time-series studies and an analysis of a cohort of 352,000 people in 66 US cities during 18 years of follow-up.

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Evoked mechanical and electrical anal sphincter responses after cortical and lumbar magnetic stimulation. The benefits are maximised by using the bladeless trocar for procedures not requiring intact specimen removal. The effect of pressure of up to 9 GPa on the magnetic and structural properties of layered (La0.6Nd0.4)1.2Sr1.8Mn2O7 manganite has been investigated. Three of the patients had already received a systemic to pulmonary artery shunt. Our study suggests that customized growth assessment may have better accuracy in predicting adverse perinatal outcome than growth velocity in small fetuses with normal zebeta drug classification umbilical Doppler delivered at term. Bortezomib is ineffective in an orthotopic mouse model of pancreatic adenocarcinoma.

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Forty-five spine radiographs of skeletally immature patients (age, two months to four years) with infantile idiopathic scoliosis were measured with use of Surgimap software. Our data indicate that 5 SNPs in the NOS1, TACR1, TACR3, and KIT genes could be involved in STC, especially rs3771863 in intron 1 of TACR1, which showed the highest association. Finally, the third experiment showed that presenting a noise before a single 20-ms burst may improve discrimination performance in some listeners, but not sufficiently to account for the results of the first experiment purely in terms of an improvement in the discriminability of the second tone burst in the pair. The demonstration of changes in bulbar conjunctiva surface epithelium in the psoriatic patients treated with PUVA. Few studies have addressed the impact of menopausal symptom severity over quality of life (QoL) in Latin American women with different ethnics. The population of China will go to a descending track around 2030. Surprisingly, the positions of key Raman bands of wild-type dsFP483 are cost of clomid treatment most similar to those of the neutral GFP chromophore, whereas the K70M spectra are more closely aligned with the anionic form. The paper provides a systematization of the scientific evidence on quality of life of patients affected by urinary incontinence (UI) and overactive bladder (OAB) through a systematic literature review. Organization and exon-intron structure of vole Oct4 gene are similar to the gene organization in other mammalian species. The contribution of hippocampal neural activity to cerebellar learning is only possible if there is a functional connection between the two structures.

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