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We have now examined the effects on cell motility of drugs or treatments known to affect various pathways of protein secretion. Heterogeneous catalysis by phospholipase A2: formulation of a kinetic description of surface effects. In addition, the more recently reported nuclear effects are discussed as well as secondary events (Stage II) that spread over the whole liver and may be relevant targets for clinical treatment. We have investigated this particular aspect of insulin action by 125I-insulin binding studies. These assays, which are most often performed in well plates, would be greatly improved by a practical method to pattern a series of antigens on a flat surface and to localize their binding to many analytes. Cyclopia was suggested by the central placode, the latter consisting of a thin, stratified, squamous nonkeratinized epithelium attached to an incomplete orbit by a strand of connective tissue.
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Classical aversive conditioning of catecholamine and corticosterone responses. Cardiovascular effects of acetaldehyde accumulation after ethanol ingestion: their modification by beta-adrenergic blockade and alcohol dehydrogenase inhibition. The activity of hypoxanthine-guanine phosphoribosyltransferase in unfertilized mouse ova and in mouse embryos at the two-cell stage is proportional to the number of X chromosomes present during oogenesis. Stimulation of DNA synthesis in lungs of hamsters tolerant to nitrogen dioxide. (Case 1) Nine-year-old female developed attack of abnormal sensation in her left upper limb followed by motor seizure in her left limbs since 5 years old. Expression of thymidine phosphorylase in uterine sarcoma and uterine leiomyoma: association with microvessel density and Doppler blood flow analysis. Previously we have shown by Northern analysis that TGFbeta1mRNA was well expressed in normal adrenal and in adrenocortical adenomas but reduced in carcinomas. Morphological and biomechanical evaluations of neocartilage from the repair of full-thickness articular cartilage defects using rib perichondrium autografts: a long-term study.
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A further assessment of attention-placebo effects and demand characteristics in studies of systematic desensitization. The growth in the cap was so active that is sometimes mimicked sarcoma, but no true anaplasia was seen. This paper proposes a model of the relationship between values, in particular health value, and adjustment to illness. Again this blockade may be overcome by using larger doses of active Newcastle virus. Histopathological studies in animal and human renal tissues have shown the efficiency of the biopsies. Woven Dacron grafts induced significantly higher release of both TNF-alpha and IL-6 compared to ePTFE. In May 1996, the World Health Assembly discussed occupational health and adopted a resolution on the WHO Global Strategy for Occupational Health for All (WHA49.12), requesting the Director-General to promote the implementation of the Global Strategy for Occupational Health for All within the framework of the Ninth General Programme of Work. Results show dyspnoea to be the only symptom strongly influencing survival. Crevicular fluid from gingivitis patients contains significant levels of a cysteine protease which was characterized as the lysosomal protease cathepsin B, as judged by substrate specificity, thiol dependence, pH optimum, kinetic parameters, pH stability, and inhibitor sensitivities.
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It is particularly indicated in cases of ascites occurring by itself due to a neoplasm or of undiagnosed origin, and in cases of infiltration of the pelvic nodes or when a small abdominal mass, whether it is isolated or associated with ascites, is found. Comparison of new chemical method of determining isonicotinoyl hydrazide in serum with microbiological assay. The variables which lead to this reaction are described in detail. A significantly higher incidence of post-operative haemorrhage occurred in the group aged 16-25 years and significantly more males suffered post-operative haemorrhage. We conclude that racial groups differ somewhat in their characteristic autoimmune responses to individual autoantigens.
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Hepatotoxic effect of 2 anovulatory steroids, mestranol and norethisterone acetate in the rat. Acute short-term diabetes augmented D-3-hydroxybutyrate utilization and oxidation at 1.25 and 2.5 mM DL-3-HB, with no significant effect at higher concentrations, but increased acetoacetate production at all investigated concentrations. Genetic factors influence the atherogenic response of lipoproteins to dietary fat and cholesterol in nonhuman primates. Mitochondria and microfilament distribution within the same cell did not show such a correlation. The tumor was inoperable because of its location and the invasion of adjacent structures. Thus immediate postcholangiogram surgery was not required in these patients. l-Ephedrine, and adrenoceptor agonists and antagonists were orally administered immediately before PCA provocation. Effect of carbon disulfide on liver function in vivo and in the isolated perfused liver. The history of a 6-month-old girl is presented, in whom this syndrome was complicated by congenital Cushings syndrome.
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Electrophoresis underestimates the concentration of polyclonal immunoglobulins in serum. Synthetic alphah-17-39 ACTH was used in our radio-immunoassay in order to measure the C-terminal ACTH activity of the neuro-intermediate lobe. Oral anticoagulant therapy with a coumarin derivative was started concomitantly and continued for 12 weeks. Closed segments of human saphenous vein, containing saline or blood were used to study whether hypoxia and/or hypercapnia develops during one hour of storage. Differential daily expression of Per1 and Per2 mRNA in the suprachiasmatic nucleus of fetal and early postnatal mice. The average costs of stomach, colorectal, and cervical cancer screening programs increased and the average cost of the lung cancer screening program decreased, as the number of persons screened increased. Tumor areas were measured on alternate days beginning on the second or third day after implantation for 13 or 14 days. The same inhibition is found when the platelets originate from rats pretreated with aspirin. Role of mitochondria in the development of the enlarged heart muscle. Identification of these proteins by tandem mass spectrometry has revealed several classes of proteins involved in the regulation of membrane fusion and secretion.
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Characterization of the type and group specificities of the immune response in mice to murine leukemia viruses. Cardiac interbeat interval and respiratory sinus arrhythmia were measured to assess vagal tone. Oncological scintigraphy is described in two dogs with malignant lymphoma and malignant schwannoma, respectively. Effect of acetaminophen on fetal acid-base balance in chorioamnionitis. Biopsies of other grafts were done, and fibroblasts grown from them were karyotyped to determine the percentage of donor fibroblasts remaining in the graft. Prostheses were replaced mainly under general anaesthesia if they leaked or resulted in difficult phonation.
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Several parallel computing approaches have been taken to attack the most computationally expensive phase of molecular simulations, the evaluation of long range interactions. Somatostatin blocks the potentiation of TRH-induced TSH secretion from perifused pituitary fragments and the change in intracellular calcium concentrations from dispersed pituitary cells elicited by prepro-TRH (PS4) or by tri-iodothyronine. Thyroidal 131 I accumulation in the garter snake, Thamnophis sirtalis L. There are various pharmacological approaches to improving glucose homeostasis, but those currently used in clinical practice either do not succeed in restoring normoglycaemia in most patients or fail after a variable period of time. Haematogenous micro-abscesses are sometimes found in the conducting tissues.
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Correlation of incidence rates for selected cancers in 29 census sub-divisions of Alberta, Canada, 1961-1981. Compression of intramyocardial arterioles during cardiac contraction is attenuated by accompanying venules. Hygiene conditions in relation to ice cream produced by small shops. It is argued that disagreements that arise because of medical uncertainties are not disagreements about facts, but disagreements in attitude, where appeal to expertise is not possible. Potential temperature rise induced by electromagnetic field in brain tissues.