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Axedol (Tramadol)

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Axedol is used for the management of pain in adults. Although it's a little weaker than other opioids, it can still be addictive and habit-forming. Axedol is available as both an immediate-acting tablet and an extended-release tablet.

Other names for this medication:
Adamon, Antram, Armadol, Arodol, Avdol, Cradol, Didol, Dolfre, Dolotram, Dolriz, Dolstar, Doltel, Domadol, Eltram, Hyperdol, Kamadol, Kevtram, Lagesic, Leedol, Medol, Midol, Moludol, Novadol, Opidol, Opigesic, Orchidol, Ospidol, Painadol, Paintrol, Pentazen, Postadol, Ryzolt, Sedate, Siatram, Standol, Takol, Tandam, Tramabit, Tramafen, Tramaflam, Tramak, Tramasol, Tramazac, Trandy, Transic, Trazac, Trofel, Trydol, Vintram

Similar Products:
Retin, Geodon, Imodium, Imovane, Cleocin, Requip, Lopid, Zetia

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Axedol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Axedol ER.

Never share Axedol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Axedol ER.

Axedol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Axedol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Axedol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Axedol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Axedol ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Axedol XL dosage information

Side effects

The most common side effects associated with Axedol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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The importance of citrates in treatment and prophylaxis of calcium oxalate urinary stones. Patients aged 0 to 18 years who presented with a splint were prospectively enrolled. Resistance against the aphid Macrosiphum euphorbiae previously was observed in tomato and attributed to a novel gene, designated Meu-1, tightly linked to the nematode resistance gene, Mi. DL comparisons, and, strikingly, all of these genes exhibited opposing expression trends between these two comparisons, strongly suggesting that these overlapping DEGs are somehow involved in the responses of tobacco leaves to drought stress. Additional exogenous LH activity in the form of either recombinant luteinizing hormone or low-dose recombinant hCG is unnecessary in microdose cycles to increase pregnancy rates. Overall, the in vitro parameters and alterations of membrane protein profiles indicated that pathogen inactivation treatment impacts RCC quality more severely than gamma-irradiation and that it may induce damage through a predominately oxidative mechanism. In chimeric mice, gene disruption experiments have demonstrated a critical role for Epo signaling in development beyond the erythroid colony-forming unit (CFU-e) stage. The recent evidence that certain medicinal plants possess hypoglycemic, lipid-lowering, and immunomodulating properties on account of their rich flavonoid and/or other glucose-lowering active constituents merits scientific scrutiny in this regard.

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The aim of this study was to investigate the side-effects of cosmetic preservatives, by evaluating objective and subjective skin irritation. To assess the efficacy of transperineal biopsy to detect prostate cancer, we compared this approach to systematic sextant transrectal biopsy in a simulation experiment. Currently available automated motion capture modalities offer a highly accurate means of assessing general motion, but are also limited to a highly controlled setting. The software is demonstrated with application to a comprehensive study of eight plant transcriptomes. Serum levels of interleukin-12 (IL-12) and gamma-interferon (gamma-IFN) were significantly increased in mice, which showed a severe ear edema induced by the type IV allergy in comparison with those of normal mice.

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The influence of normal cells on the growth and fate of transformed cells has been described repeatedly. Submerged in darkness: adaptations to prolonged submergence by woody species of the Amazonian floodplains. The patient was free of symptoms on the first postoperative day. Usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery. This study was designed to determine threshold values for betaTP concentrations in nasal cavity secretions as a predictor of CFS leak.

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This case not only represents an unusual manifestation of acute appendicitis, but also alerts us to the importance of anatomical considerations when interpreting disease extent with imaging. A self-administered questionnaire was mailed to all of the 160 registered veterinary practices in Western Australia. The present review will highlight recent information on stem cells and bone repair and examine potential avenues for future research. Knowledge development and evidence-based practice: insights and opportunities from a postcolonial feminist perspective for transformative nursing practice. A critical comparison is made on the conceptual constraints introduced when developing the two most utilized reference thermodynamic networks. Light intensity and wavelength during embryo manipulation are important factors for maintaining viability of preimplantation embryos in vitro.

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Cerebral aneurysms were induced in rats by means of the combination of ligation of the unilateral common carotid artery and induced hypertension. Universal or public health prevention seems to be the most suitable form because several other cofactors of morbidity and mortality of affluent societies can also be prevented. None of these three compounds affected larval mortality as was the case with several of the analogs tested. Immunization of hypercholesterolemic animals with oxidized LDL has been shown to inhibit atherosclerosis demonstrating that at least some of these immune responses have a protective effect. Atomic force microscopy study of the antimicrobial action of Sushi peptides on Gram negative bacteria.

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In this spiral, the final outcome will ultimately be the creation of productive faculty (and future nurse mentors), along with improved faculty group dynamics and teamwork, or just another vacant position. Transient low-dose methotrexate induces tolerance to murine anti-thymocyte globulin and together they promote long-term allograft survival. Genetic perturbations suggest a role of the resting potential in regulating the expression of the ion channels of the KCNA and HCN families in octopus cells of the ventral cochlear nucleus. The purpose of this study was to evaluate the effectiveness of dentin disinfection by different antibacterial solutions in the presence and absence of detergents using a novel dentin infection model and confocal laser scanning microscopy (CLSM). We tested the ability of electric pulse-stimulated gene transfection from a substrate to overcome low expression efficiency and cross contamination between spots on arrays. The aim of the present population-based study was to examine the prevalence of significant social anxiety (SSA) in preadolescent children and compare their characteristics with those of children without SSA. Electron microscopic study demonstrated blister formation beneath the basal lamina and lost anchoring fibrils of both tissues.

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colony numbers using selective agar plates and confirmed that the abundance of Lactobacillus spp. Our results also indicate that the formation of such nanobubbles in small organic molecule aqueous solutions is a universal phenomenon. This study, drawing upon data collected as part of a randomized clinical trial of alcohol treatment matching effects, investigates the relationship between research follow-up assessment interviews and subsequent drinking behaviors. As a basis for the interpretation of the excitation dephasing and energy transfer pathways, a superlattice-like structural model is proposed based on recent experimental data and computer modeling of the Bchl c aggregates (1994. To investigate whether the observational skills of doctors and nurses can be improved by arts-based observational skills training. Little information, however, exists concerning this gene family in teleost fish. Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn. Merely recommending donor oocytes without exploring other options is inappropriate. Number of adolescents referred to mental health services during the last year. Collectively, these results suggest that alpha v integrin complexes provide the P2Y2R with access to G12, thereby allowing activation of this heterotrimeric G protein that controls actin cytoskeletal rearrangements required for chemotaxis.

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To examine how DNA DSBs might lead to GCRs, we investigated the repair of a single DNA DSB in a structurally unstable cell line. Ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) share similarities and are classified as spondyloarthropathies. The main advantage in using the Grotenhuis perforator was in displacing the floor of the third ventricle away from the basilar artery during perforation. IDM1 is required for preventing DNA hypermethylation of highly homologous multicopy genes and other repetitive sequences that are normally targeted for active DNA demethylation by Repressor of Silencing 1 and related 5-methylcytosine DNA glycosylases. Cigarette smoking and primary liver cancer: a population-based case-control study in US men. The main extracellular matrix-producing cell types are retinoid-storing pancreatic stellate cells (PSCs) of mesenchymal origin. The ACC was subdivided into the subgenual, pre-callosal, rostral-anterior and caudal-anterior ACC. This article is a selective review and synthesis of relevant research findings from genetic studies of major mood disorders and the application of these to clinical practice.

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Overall, our results corroborate previous data suggesting that aripiprazole is effective and safe in most patients. Health systems across the United States have started their journeys toward population health management and the future of accountable care. Effects of natural and novel synthetic jasmonates in experimental metastatic melanoma. Similarly, trials failed to establish a role for IVIG in the treatment of secondary or primary progressive MS. In particular, the ability to detect modest genetic effects can be severely compromised. All statistical dispositions were done in SPSS including description and regression analysis. However, this result should be treated with caution since it comes from only one small RCT. Awareness of the natural clinical history, potential for severe morbidity or mortality, and associated complications are extremely important. Ischaemic preconditioning is an endogenous mechanism of myocardial protection which may allow us to slow the progress of myocardial necrosis, increasing the time available for effective reperfusion.

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Dual staining of immunoglobulins and cellular DNA was employed to determine immunoglobulin pool size as a function of cell-cycle phase. In this pilot study CMR did not reliably identify ACR-related changes in pediatric HT patients. Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands. Furthermore, CH11-dependent induction of the ASK1-JNK/p38 pathways was found to activate the transcription factors AP-1 and ATF-2, and FADD-caspase-8-Bid signalling, resulting in the translocation of both Bax and Bak proteins, and subsequently mitochondrial dysregulation that is characterized by the loss of mitochondrial membrane potential (DeltaPsim), cytochrome c release and cleavage of caspase-9, caspase-3 and PARP. Both halves were then sputtered with gold and examined using SEM. It was possible to assign specific volatile compounds to distinctive events in the bioprocess. The scores of the total SCIM and of the four subscale was recorded at admission and discharge.

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A mathematical model was used to estimate the number of patients needed for revenues to exceed costs. The bonding between fiber posts and luting agents was affected by the type of fibers and polymerization mode of the cement. In nearly all cases of clinical improvement, no deterioration recurred. Staff members were aware of the value of this type of analysis but also recognized that real learning would best be achieved through completing an FMEA of an existing process or situation, rather than through a simulation or staff training. Children with intracranial AVMs present a special challenge in therapeutic decision-making because of the early recognition of their future life-long risks of hemorrhage if they are treated conservatively. Therefore, routine CRP determination cannot be recommended in patients with CKD to stratify their cardiovascular risk (Strength of Recommendation C). Far from representing the mere addition of new methodological techniques, these disciplines (especially, forensic taphonomy) provide forensic anthropology with a new conceptual framework, which is broader, deeper, and more solidly entrenched in the natural sciences. Genetic origins and clinical phenotype of familial and acquired erythrocytosis and thrombocytosis. A nonamethine analogue of this compound was also synthesized and exhibits a slightly larger Re(gamma) with respect to a previously reported bis(dioxaborine)-terminated nonamethine. Brain protein concentration was also not affected by chronic administration of PPA, in contrast to G-NeuAc concentration which was significantly reduced in the cerebellum.

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Visualization of intestinal splenosis by somatostatin receptor scintigraphy. Oldie but goldie: Bristow-Latarjet procedure for anterior shoulder instability. Before gait analysis, 60 ambulatory children aged 10 (4-18) years with spastic cerebral palsy had a specific surgical plan outlined, based on clinical examination by orthopedic surgeons. Doxorubicin and cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil as adjuvant chemotherapy in breast cancer. The contribution of the PHC to LTM encoding thus crucially depends on whether an item was successfully processed in the WM task. Predicting hemodialysis mortality utilizing blood pressure trends is zyrtec d a prescription drug . Current and emerging concepts in the management of neovascular age-related macular degeneration. Xerostomia and salivary hypofunction in vulnerable elders: prevalence and etiology. Aging impairs functional, metabolic and ionic recovery from ischemia-reperfusion and hypoxia-reoxygenation. Malaria was considered a major threat to life but relevant knowledge was a chimera of scientific knowledge and traditional beliefs, which combined with socio-economic circumstances, leads to ineffective malaria prevention.

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This new classification includes 4 risk levels (levels 1-4) according to residual disease magnitude after neoadjuvant chemotherapy in 710 patients with operable breast cancer. T administration dose dependently increases muscle mass and maximal voluntary strength. Measurements of skin fold thickness combined with BIA are quite sufficient for routine clinical practice. Univariate correlation and multiple regression analyses were performed to assess the linearity of the relationships among the variables. Severe events seem to be related to onset of bipolar episodes, although it remains unclear whether severe events relate differentially to depressive and manic onsets. Based on our results and previous literature data it could be suggested that neuropeptides may be involved in the development of psoriatic lesions. Mutations in the smooth endoplasmic reticulum (sER) calcium channel Inositol Trisphosphate Receptor type 1 (IP3R1) in humans with the motor function coordination disorders Spinocerebellar Ataxia Types 15 and 16 (SCA15/16) and in a corresponding mouse model, the IP3R1delta18/delta18 mice, lead to reduced IP3R1 levels. Neo-adjuvant chemotherapy followed by liver surgery is associated with improved survival and low CIRM and re-resection rates.

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Angiographic analysis demonstrated filling of the eyelid arcades, provided the anastomoses between the internal and external carotid branches were preserved. Comparisons of the anthrax P4H structure with Cr P4H-1 structures reveal similarities in a peptide surface groove. Overall, these results demonstrate that serotonin is able to activate nNOS, leading to the generation of reactive oxygen species (ROS) in addition to the NO(.-) production. There has been considerable interest in the extent to which substance use and unemployment may be related, particularly the causal pathways that may be involved in these associations. To evaluate the use of transient response second harmonic imaging (HI) by means of ultrasound to assess abnormalities of cerebral echo contrast agent enhancement in patients with acute stroke.

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The rabbit remained visual and comfortable 5 months postoperatively and free of recurrence of the limbal mass 9 months after initial presentation. Intrapulmonary administration of a p38 mitogen activated protein kinase inhibitor partially prevents pulmonary inflammation. Twenty heavy users who were identified in a quantitative preliminary study were interviewed using a qualitative analysis of the contents. Little is known of the mechanisms regulating the differentiation of these cells. Seventy-seven consecutive patients scheduled for minor oral surgery were interviewed using semistructured interview techniques to identify those areas of life (domains) that patients believed will be affected by minor oral surgery. Palliative treatment modalities focus predominantly on improving quality of life. The formation mechanism of the nickel nanoparticles outside the surface of CMK-3 was preliminarily discussed. Preparation and characterization of vinyl-functionalized mesoporous organosilica-coated solid xanax medication generic name -phase microextraction fiber. The effects of 17AAG were tested at concentrations of 10 and 100 nM on various parameters, including growth inhibition of the cells, enhancement of radio-sensitivity by colony formation assay, apoptosis and chromosomal radio-sensitivity and abrogation of radiation induced G2/M checkpoint.

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The apex of the lung is surrounded complicatedly by the clavicle, the first rib, the subclavian artery and vein, and the brachial plexus. Numerous new genes have recently been identified in genome-wide association studies for type 2 diabetes. A pandemic of obesity is sweeping all across the globe and the Middle East region also does not remain untouched by this prevailing pandemic. We wished to determine the prognostic factors of survival and effect of treatment on survival rate in patients with ATC. For example, in 2DFT imaging blurring and ghosting are seen and the appearance of motion artifacts remains one of the major drawbacks in MR imaging. It is possible to determine spectral components of the IOP pulse wave up to the fifth harmonic by a spectral analysis of dynamic contour tonometry continuous readings. The trend and seasonality of hospitalizations rates (HRs) for IS were analyzed stratifying by gender and age groups. Patients with Ehlers-Danlos syndrome type IV have thin-walled, friable arteries and veins. Insect visual homing strategies in a robot with analog processing.

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The aim was to design and validate a conceptual model for an EMRS to improve diabetes management in SSA making use of the HIV and TB experience. The biological information of these proteins was searched in the database of these peptide mass finger-printing (PMF). Creation of arrays of cell aggregates in defined patterns for developmental biology studies using dielectrophoresis. Their inheritance and development of several thousand years make the complicated nomenclature of acupuncture and moxibustion more confusing, unclear classification, unclear definition. Presenilin 2 is secreted in mouse primary neurons: a release enhanced by apoptosis. Carbonic anhydrase II in the endothelium of glial tumors: a potential target for therapy. We compared the effects of various cycles of IC and PC in the rat liver. Complementation experiments demonstrate that insulin interacts in trans with both receptor binding sites to generate high-affinity interactions.

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Lysosomal hydrolases catalyze the degradation of a variety of macromolecules including proteins, carbohydrates, nucleic acids and lipids. Last research promotes the endocannabinoid system modulation by inhibition of endocannabinoids hydrolytic enzymes instead of direct activation of endocannabinoid receptors to avoid detrimental effects on cognition and motor control. The C-terminal domains of adenovirus serotype 5 protein IX assemble into an antiparallel structure on the facets of the capsid. Patients were registrants from the European-American Pheochromocytoma-Paraganglioma and German von Hippel-Lindau Disease Registries. Expression level of a transgenic lambda2 chain results in isotype exclusion and commitment to B1 cells. The aim of this study was to evaluate the synergistic therapeutic effect of DEX and L-arg in rescuing the mice from experimental septic shock induced by bacterial lipopolysaccharide (LPS). Some individual herbs reduced peanut-induced anaphylactic symptoms but no single herb offered full protection from anaphylactic symptoms equivalent to FAHF-2.

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Physicians have lower adjusted voting rates than lawyers and the general population, suggesting reduced civic participation. A new method is proposed to estimate the national cancer incidence after adjusting for completeness of cancer registries. Antiretroviral use for prevention and other factors affecting the course of the HIV-1 epidemic. Risk stratification based on the clinical factors at diagnosis is closely related to the survival of localized osteosarcoma. To compare the cost of phacoemulsification with foldable lenses with that of manual small-incision cataract surgery (SICS) in a hospital setting. The introduction to this special issue is designed to reflect on some what are the side effects of ambien 10 mg of the differences between the humanities/arts and the sciences on the subject of reproduction now and in the past. are one of the most important groups of food-borne pathogens worldwide. The authors analyze Italian laws, in light of changes introduced with Legislative Act n. We speculate that this derangement of LIGHT may be important for atherogenetic process of ischemic stroke.

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However, AL-09 has an altered dimer interface that is rotated 90 degrees from the kappaI O18/O8 dimer interface. The assay detected specific antibodies to fluke cysteine proteinases without the need for purified proteinases. We recommend checking the follow-up MRI at a cumulative BED(10) of around 65 Gy to point A, with the initial BT modified at a final booster BT session. Predictors of survival in patients with locally advanced thymoma and thymic carcinoma (Masaoka stages III and IVa). We also confirmed the implementation of a telecontrol function for the surgical robot. Results show that the range and the strength of the interactions in these solutions are highly affected by the presence of PEG. This research aimed to construct a quaternary structural model of Artemia HbII that shows the interpolymer interface and domain-domain alignment, using the MS3D (mass spectrometry for three dimensional analysis) approach. We selected the participants in the control group from a waiting list. From the results of the study conclusions for nursing education are drawn. The mean age of the workers who participated in this para que sirve el enalapril maleato 20 mg study falls in the range of 25-55 years.

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