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Azelastine nasal spray is used to help relieve symptoms (eg, stuffy or runny nose, itching, sneezing) of seasonal (short-term) or perennial (year-round) allergic rhinitis (hay fever), vasomotor rhinitis, or other upper respiratory allergies.

Other names for this medication:
Astepro, Azelast, Azelastine, Azenate, Duonase, Nazomac, Oculast, Optihist, Optivar

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Azelastine belongs to a group of medicines called antihistamines. Azelastine provides relief from bothersome nasal symptoms such as congestion, itchy/runny nose, sneezing and postnasal drip due to seasonal allergens or environmental irritants. Azelastine is steroid-free, does not contain pseudoephedrine, and relieves your symptoms by blocking the effects of histamine - the primary cause of allergy symptoms. What makes Azelastine unique is that it is a steroid-free antihistamine nasal spray that provides symptom relief whether the trigger is an allergen (grass, trees, pollen, mold, etc.), an irritant (cigarette smoke, perfume, cleaning agents, car exhaust, cold air, etc.), or both. Azelastine is also know as Azelastine, Arzep, Rhinolast, Alerdual, Allergodil, Rinalin. Generic name of Azelastine is Azelastine.


This section provides information on the proper use of a number of products that contain azelastine. It may not be specific to Azelastine Ready-Spray. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of side effects.

This medicine usually comes with patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Follow the instructions on the medicine label if you are using this medicine without a prescription.

This medicine is for use only in the nose. Do not get any of it in your eyes or on your mouth. If it does get on these areas, rinse it off with water and call your doctor right away.

Do not use this medicine for any other nose problem (eg, ulcers or surgery, or injury that has not healed) without checking with your doctor first.

To use the spray:

When you use the azelastine nasal spray for the first time, you must prime the spray. Press down fully 6 times or until a fine spray comes out. Prime the spray after each time you clean the pump, or if you have not used the medicine for 3 days or longer, by spraying the medicine 2 times or until a fine spray comes out. Blow your nose to clear your nostrils. Tilt your head down, looking at your toes, and insert the tip of the nose piece into your nostril. Hold bottle upright and aim the spray tip toward the back of your nose. Tilt your head downward while spraying to avoid a bitter taste in the mouth. Close your other nostril with a finger. Press the pump 1 time and sniff gently at the same time, keeping your head tilted forward and down. Repeat in your other nostril using the same steps. If your healthcare provider tells you to use 2 sprays in each nostril, repeat the steps above for the second spray in each nostril. Do not blow your nose or tip your head back after using the spray. Wipe the tip of the outside of the nose piece with a clean, dry tissue or cloth and put the cap back on.

Do not drink alcohol while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For nasal dosage form (Azelastine® spray): For treatment of seasonal allergic rhinitis: Adults and children 12 years of age and older—1 or 2 sprays in each nostril 2 times a day, or 2 sprays in each nostril once a day. Each spray contains 137 or 205.5 micrograms (mcg) of azelastine. Children 6 to 11 years of age—1 spray in each nostril 2 times a day. Each spray contains 137 or 205.5 mcg of azelastine. Children 2 to 5 years of age—1 spray in each nostril 2 times a day. Each spray contains 137 mcg of azelastine. Children younger than 2 years of age—Use and dose must be determined by your doctor. For nasal dosage form (Astepro® spray): For treatment of perennial allergic rhinitis: Children 6 months to 11 years of age—1 spray in each nostril 2 times a day. Each spray contains 137 micrograms (mcg) of azelastine. Children younger than 6 months of age—Use and dose must be determined by your doctor. For treatment of seasonal allergic rhinitis: Adults and children 12 years of age and older—1 or 2 sprays in each nostril 2 times a day. Each spray contains 137 micrograms (mcg) of azelastine. Children 2 to 11 years of age—1 spray in each nostril 2 times a day. Each spray contains 137 mcg of azelastine. Children younger than 2 years of age—Use and dose must be determined by your doctor. For nasal dosage form (Astepro® allergy spray): For treatment of allergic rhinitis or other upper respiratory allergies: Adults and children 12 years of age and older—2 sprays in each nostril once a day or 1 or 2 sprays in each nostril 2 times a day (every 12 hours). Do not use more than 4 sprays in each nostril per day (24 hour period). Each spray contains 205.5 micrograms (mcg) of azelastine. Children 6 to 11 years of age—1 spray in each nostril 2 times a day (every 12 hours). Do not use more than 2 sprays in each nostril per day (24 hour period). Each spray contains 205.5 micrograms (mcg) of azelastine. Children younger than 6 years of age—Use is not recommended.


If you overdose Azelastine and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and sunlight. Keep in a tightly closed container. Throw away the after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Azelastine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Drinking alcohol with this medicine can increase certain side effects.

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With meats, frying or broiling resulted in higher in vitro mutagenicity (10- to 50-fold) than did baking or boiling, whereas for carbohydrates, eggs or vegetables mutagenicity did not vary markedly with cooking method. However, in the presence of normal human serum, CL values with K7 strains increased considerably, whereas the CL response to K2 isolates was unaffected. The patient had generalized seizures in conjunction with fever at 3 and 5 years of age. Hanging in this way in about 2 weeks would stretch out and relax the soft tissues on the convex side, resulting in maximum correction. We also give a detailed review of the previously published articles on CFC syndrome and discuss the differences between CFC, Noonan, and Costello syndromes. Hereditary gingival fibromatosis is a proliferative fibrous lesion of the gingival tissue that causes esthetic and functional problems. In particular, proton MR spectroscopy, by monitoring levels of N-acetylaspartate (a putative marker of axonal integrity), has been particularly illuminating, as the extent of axonal injury associated with white matter inflammation and demyelination had not been well appreciated from classical pathology studies.

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Development of leukemoid reaction following ingestion of large doses of prednisolone. Data analysis showed that emergency nurses used various methods to prepare and maintain their triage expertise. This response ensures that acoustical feedback above approximately 1 kHz does not limit the low frequency gain, which is assumed to be very important for the speech recognition. Follow-up shows five of these patients as 100 per cent relieved, one as 75 per cent relieved. Our data suggest that in defining frequent heavy drinkers, one should consider body weight. A limited but definite need exists for vaccines against Lassa, Junin, and Machupo viruses. Birds given injections of RAV-1 failed to produce neutralizing antibody to any of the pseudotype sarcoma viruses of the various ALV, whereas many birds challenged with RAV-3 or RAV-5 produced neutralizing antibody directed against the heterologous RAV-1 as well as the homologous viruses, but not against the tolerated virus ALV-F42. Basal values, effect of glycogen depletion by exercise, and effect of treatment.

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Within pair cross-concordances of the RD and ADHD qualitative diagnoses for monozygotic twins were larger than for dizygotic twins, although not significantly so (p less than 0.10). ICC on pituitary section showed that FSH, LH, and prolactin synthesis were not affected in KO mice. All our quantitative light and electron microscopic data indicate that the antitumor action of antiprogestins is accompanied by the initiation of terminal differentiation leading to (apoptotic) cell death. A little-known problem of industrial hygiene: professional poisoning caused by lead stearate. In mitochondria with cytochrome a(t) concentrations more than 70 pmol/mg of protein, the phosphorylative activity where can i buy albendazole over the counter per mg of mitochondrial protein was considerably higher than in controls. The neoplastic transformation probability for type II cells is also discussed.

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