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Azitral (Azithromycin)
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Azitral

Azitral is a macrolide antibiotic of azalides group. Azitral contains Azithromycin as an active ingredient. Azitral inhibits RNA-dependent protein synthesis of sensitive microorganisms. It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. (including Streptococcus pneumoniae, Streptococcus pyogenes group A); gram-negative bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Haemophilus ducreyi, Moraxella catarrhalis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Neisseria gonorrhoeae, Campylobacter spp., Legionella pneumophila; anaerobic bacteria: Bacteroides fragilis.

Other names for this medication:
Amsati, Arzomicin, Azalid, Azatril, Azicid, Azicine, Azihexal, Azimex, Azitrocin, Azitrotek, Azromax, Clearsing, Disithrom, Doyle, Goldamycin, Medimacrol, Momicine, Respazit, Sitrox, Tanezox, Tridosil, Tromix, Vinzam, Zetamax, Zirocin, Zistic, Zitrex, Zitroken, Zycin

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Also known as: Azithromycin

Description

Azithromycin is used to treat certain bacterial infections in many different parts of the body. This medicine may mask or delay the symptoms of syphilis. It is not effective against syphilis infections.

Azithromycin belongs to the class of drugs known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain azithromycin. It may not be specific to Azitral Tri-Pak. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You may take Azitral® oral liquid or tablets with or without food.

Shake well the bottle of Azitral® oral liquid before each use. Measure your dose correctly with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Measure the Zmax® extended-release oral suspension with a marked measuring spoon, syringe, or cup. You or your child must take this medicine within 12 hours after it has been mixed with water. It is best to take the Zmax® extended-release oral suspension on an empty stomach or at least 1 hour before or 2 hours after a meal. If your child does not use all of the medicine in the bottle, throw it away after you give the dose.

If you or your child vomits within one hour of taking the Zmax® extended-release oral suspension, call your doctor right away to see if more medicine is needed.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

If you are taking aluminum or magnesium-containing antacids, do not take them at the same time that you take Azitral®. These medicines may keep azithromycin from working properly. However, you can take antacids with Zmax®.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release suspension): For treatment of pneumonia: Adults—2 grams (g) once as a single dose. Children weighing 34 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 grams once a day, taken as a single dose. Children 6 months of age and older weighing less than 34 kg—Dose is based on body weight and must be determined by your doctor. The dose is usually 60 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. For treatment of sinusitis: Adults—2 grams (g) once a day as a single dose. Children—Use and dose must be determined by your doctor. For oral dosage forms (suspension or tablets): For treatment of infections: Adults—500 to 2000 milligrams (mg) once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 250 to 500 mg once a day for several days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 30 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 5 to 10 mg per kg of body weight once a day for several days. Children younger than 6 months of age—Use and dose must be determined by your doctor. For treatment of pharyngitis or tonsillitis: Adults—500 milligrams (mg) on Day 1 (the first day), taken as a single dose. Then, 250 mg on Day 2 through Day 5. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight once a day for 5 days. Children younger than 2 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Azitral overdose may include nausea, vomiting, diarrhea, and stomach discomfort.

Storage

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Azitral Tablet.

Side effects

The most common side effects associated with Azitral are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take azithromycin. This includes Acid Gone, Aldroxicon, Alternagel, Di-Gel, Gaviscon, Gelusil, Genaton, Maalox, Maldroxal, Milk of Magnesia, Mintox, Mylagen, Mylanta, Pepcid Complete, Rolaids, Rulox, and others. These antacids can make azithromycin less effective when taken at the same time.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking azithromycin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid exposure to sunlight or tanning beds. Azitral can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Patients with diabetes undergoing stent implantation in SVG have: 1) higher in-hospital and late mortality, 2) higher one-year TLR rates, and 3) significantly lower one-year cardiac event-free survival. Cost considerations, complication rates, and the quality of the available evidence are also discussed. Knowledge on adherence and safety of the oral contraceptive pill in Saudi women. These strategies, which follow from our current understanding of the pathophysiology of DIC, involve inhibition of tissue factor-mediated activation of coagulation or restoration of physiologic anticoagulant pathways by means of the administration of antithrombin concentrate or (activated) protein C concentrate. Centers of gravity (COG) analysis of fMRI activation in the primary motor (M1) and sensory cortex (S1) revealed /pa/- adjacent to lip representation and /ta/- articulation to tongue representation. Forty-five PCR-positive samples and four negative samples were used to confirm the sensitivity and specificity of the rtm-PCR. Because of the overwhelming scattering of light in biological tissues, the spatial resolution and imaging depth of conventional fluorescent imaging is unsatisfactory.

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Among the different ultrasound techniques only Contrast Enhanced Ultrasound improves significantly the diagnostic risk of the biopsy although the sensitivity remains quite stable. We present the formulation of a novel model for synthesizing a local communitys collective wisdom of cancer-related resources through a combination of online social networking technologies and real-world collaborative partnerships. So far, mutations have been identified in four genes, all coding for membrane proteins including ion channels and transporters. Collusions Between Patients and Clinicians in End-of-Life Care: Why Clarity Matters. During subsequent examinations, the boy did not show signs of neurological improvement. Various optimization strategies involving the spectral, temporal, and polarization profiles of the second pulse are compared. A base-controlled synthesis of 2-substituted secondary and tertiary 1H-indole-3-carboxamides through PdCl(2)-catalyzed cyclization of o-alkynyltrifluoroacetanilides followed by isocyanide insertion has been developed.

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A novel Cys1638Tyr NC1 domain substitution in alpha5(IV) collagen causes Alport syndrome with late onset renal failure without hearing loss or eye abnormalities. Skin-electrode circuit model for use in optimizing energy transfer in volume conduction systems. A majority of cases involved the cervical cord or the cervicothoracic junction. The aim of this study was to investigate the functional role of affected brain regions in cognition in PSP compared with controls and subsequently examine these regions in FTD patients with known tau pathology (FTD tau). Serologies are of little diagnostic value and should be restricted to serologies with therapeutic implications. In this discussion of audit, the authors describe a pilot study on discharge planning. Endo FV was specific for high mannose and hybrid-type oligosaccharides.

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Markedly decreased INTS6/DICE1 mRNA levels were detected in prostate cancer cell lines LNCaP, DU145 and PC3 as well as CPTX1532 as compared to a cell line derived from normal prostate tissue, NPTX1532. The MyoD family of basic helix-loop-helix (bHLH) proteins is required for myogenic determination and differentiation. Two of these cases presented lysis of osseous tissue shown in radiologic assays. Display intensity and chromaticity, test distance, room illumination, and a number of other variables must be controlled to avoid unexplained discrepancies in test outcomes, within and between individuals and test locations. The aim of this systematic review was to evaluate the effectiveness of different therapies for lesions of the TFCC. It would be useful to know whether there is a difference in success rates between immediately or early loaded implants compared with conventionally loaded implants. Furthermore, splenocytes stimulated with the T cell mitogens, PMA/Io and anti-CD3, showed a decrease in CB1 message while cultures stimulated with the B cell mitogen, anti-CD40 antibody, showed an increase in message. This paper reviews the literature providing links among oxidative stress, accelerated erosion of telomeres, CVD, and specific sources and types of air pollutants.

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The construction and expression of eukaryotic expression plasmid of Legionella pneumophila immunogenic protein. Impact of body weight on blood pressure with a focus on sex differences: the Tromso Study, 1986-1995. Demethylation of the APC gene by 5-aza-dC may be useful for the treatment of lung cancer. and (2) Can modified assertive community treatment improve the course and outcome in young persons suffering from psychosis as compared to treatment in community mental health centres?. Clinical features and baseline demographic data were collected independently by a stroke physician and 6-month outcome by postal questionnaire. Ammonia-induced oxidation of RNA and proteins may impair postsynaptic protein synthesis, which is critically involved in learning and memory consolidation. Scaling of swim speed and stroke frequency in geometrically similar penguins: they swim optimally to minimize cost of transport.

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Keratins 8 and 18 (K8/K18) are important hepatoprotective proteins. Because the patient was clinically stable and had a functioning digestive tract, the nutritional team decided to treat her by oral nutritional support with a low-lipid diet, rich in medium-chain triacylglycerols. Nitric oxide in mechanisms of brain damage induced by neurotoxic effect of glutamate. The changing healthcare environment challenges the traditional role of academic medicine. Reduced pain and improved sleep occurred within 6 months of treatment. CD31 and CD34 immunoreactivity closely parallel both the different morphologic steps of melanocytic tumor progression and the presence of histological parameters related to the aggressive behaviour. Soymilk enriched with green coffee phenolics - Antioxidant and nutritional properties in the light of phenolics-food matrix interactions.

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The bilateral frontoparietal polymicrogyria syndrome is characterized anatomically by predominantly frontoparietal diffuse polymicrogyria and clinically by generalized tonic-clonic seizures and mental retardation developing in early childhood. The current maxolon dose mims case illustrates an unusual presentation of pulmonary cryptococcosis and raises questions regarding the therapeutic approaches proposed in the literature. This review focuses on investigations of nanomaterial interactions with the blood components involved in blood coagulation: the PCS and PLTs. Kaplan-Meier analyses were performed, with adjustments by Cox regression model. The first is due to dielectric saturation which reduces the dielectric permittivity in the vicinity of an ion.

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Previous studies have shown that it is possible to extract the drug efficacy of antivirals from the viral decay rate of chronic infections. A comparison of the behavioral observation system (BOS) with clinician ratings of psychosis and mania. Here, we briefly summarize historic viewpoints and evolutionary perspectives on vascular development. Is it necessary to insert a nasobiliary drainage tube routinely after endoscopic clearance of the common bile duct in patients with choledocholithiasis-induced cholangitis?. To assess the possible association of killer immunoglobulin-like receptor (KIR) genes, specifically KIR3DL1 what drugs may decrease theophylline levels , KIR3DS1 and KIR3DL2, with ankylosing spondylitis (AS). Two mechanistically distinct immune evasion proteins of cowpox virus combine to avoid antiviral CD8 T cells.

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