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Azitrobac (Azithromycin)
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Azitrobac

Azitrobac is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Other names for this medication:
Azatril, Azenil, Azibiot, Azicine, Azicip, Azimakrol, Azimycin, Azithin, Azithromycin, Azithromycinum, Azitro, Azitrocin, Azitrolit, Azitromicina, Azitrotek, Azomac, Azycyna, Bactrazol, Cinalid, Clearsing, Disithrom, Doyle, Hemomycin, Imbys, Koptin, Macrozit, Neblic, Neofarmiz, Neozith, Orobiotic, Pretir, Rarpezit, Simpli, Texis, Ultrabac, Zaret, Zentavion, Zetamax, Zifin, Zithrocin, Zithrox, Zitroken, Zitromax, Zocin

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Also known as: Azithromycin

Description

The drug is an antibiotic used to treat a variety of bacterial infections, such as cat-scratch disease, ear infections, infections of the skin or surrounding tissue, and throat or tonsil infections.

Azitrobac is also used to treat lung and other respiratory infections, such as bronchitis, sinusitis, community acquired pneumonia, some cases of chronic obstructive pulmonary disease (COPD), and whooping cough (pertussis).

Doctors may also prescribe azithromycin for genital infections and sexually transmitted diseases, such as gonorrhea, infections of the urethra or cervix, genital ulcers, and severe pelvic inflammatory disease.

Azitrobac belongs to group of drugs known as macrolide antibiotics. They work by preventing bacteria from making their own proteins.

As with other antibiotics, to prevent the spread of drug-resistant infections, the Food and Drug Administration (FDA) strongly advises doctors to prescribe the drug only when there is proof, or a strong suspicion, that the infection is caused by bacteria against which Azitrobac is effective.

The FDA first approved Azitrobac under the brand name Zithromax in 1991. Pfizer Pharmaceuticals manufactures the drug.

Dosage

It is important that your child completes the course of antibiotic. This means that they must take the medicine for the number of days that the doctor has told you to, or until all the medicine has been taken. If you stop giving the antibiotic too soon, the troublesome bacteria that are left will start to multiply again, and may cause another infection. There is also a risk that these bacteria will be resistant to (no longer be killed by) the first antibiotic. This means that it might not work next time, and your child might need a different antibiotic, which might not work as well or cause more side-effects.

Children are sometimes sick (vomit) or get diarrhoea when taking antibiotics. Encourage them to drink water to replace the fluid they have lost. If it is severe or your child is drowsy, contact your doctor.

Do not give your child any medicine to stop the diarrhoea unless your doctor has told you to, as this can make things worse.

Try to give the medicine at about the same times each day, to help you remember, and to make sure that there is the right amount of medicine in your child’s body to kill the bacteria.

Only give this medicine to your child for their current infection.

Never save medicine for future illnesses. Give old or unused antibiotics to your pharmacist to dispose of.

Only give the antibiotic to the child for whom it was prescribed. Never give it to anyone else, even if their condition appears to be the same, as this could do harm.

Overdose

Adverse reactions experienced at higher than recommended doses were similar to those seen at normal doses particularly nausea, diarrhea, and vomiting. In the event of overdosage, general symptomatic and supportive measures are indicated as required.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Azitrobac® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Azitrobac dosage information

Side effects

The most common side effects associated with Azitrobac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Ketolide allergy. History of cholestatic jaundice/hepatic dysfunction associated with prior use.

Pneumonia: oral treatment is for mild, community-acquired cases suitable for outpatient therapy only. Discontinue if signs/symptoms of hepatitis occur. Known QT prolongation, proarrhythmic conditions, clinically significant bradycardia: avoid. Allergic symptoms may recur after initial successful symptomatic treatment. Myasthenia gravis. Hepatic or renal impairment. Elderly. Pregnancy (Cat.B). Nursing mothers.

Avoid concomitant aluminum- or magnesium-containing antacids. Monitor with digoxin, phenytoin, warfarin. Monitor for azithromycin toxicity (eg, liver dysfunction, ototoxicity) with nelfinavir. Concomitant Class 1A (eg, quinidine, procainamide), or Class III (eg, dofetilide, amiodarone, sotalol) antiarrhythmics, or others known to prolong the QT interval: avoid.

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Residual tobacco smoke: measurement of its washout time in the lung and of its contribution to environmental tobacco smoke. The reliability of self-reported smoking status is unknown in MS. Here, we tested this proposal on a realistic experimental platform, comprising an associative network linking a 16 degrees of freedom robotic hand and a simple visual system. Thus, the authors believe a comprehensive workup and follow-up in the context of a multidisciplinary approach is necessary. Each factor was evaluated using a 1-10 scale, starting with 1-grade which was treated as very unsatisfactory through grades 2, 3, 4, 5, 6 up to a very satisfactory grade. We evaluate 4 different implant techniques of the subcutaneous implantable cardioverter-defibrillator.

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Evaluating online continuing medical education seminars: evidence for improving clinical practices. A retrospective study of clinico-pathological characteristics of colonic polyps in adults seen at a tertiary care centre. Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb. The efficiency of TMPyP acting in concert with ADM in the dark and in the presence of photoirradiation was evaluated, by studying cell viability, caspase-3 activity and ultrastructural changes in the cells after incubation with each of the two agents, separately, or simultaneously as a co-mixture. The mean age at surgery was 31.5 months (17 to 64) and the mean follow-up was 11.8 years (3.8 to 19.5). Differentially expressed genes in Mycobacterium tuberculosis H37Rv under mild acidic and hypoxic conditions. Prevention is the safest and the most efficient method in the care concerning AMS. Analysis of the first Australian strains of Bartonella quintana reveals unique genotypes. Characterisation of Lafora-like bodies and other polyglucosan bodies in two aged dogs with neurological disease.

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Benzodiazepine and antidepressant use in elderly patients with anxiety disorders: a survey of 796 outpatients in Japan. Thus, long-term results of SVR associated with multiple coronary artery bypass grafting (CABG) for MVCAD (group 1) were compared with SVR with or without CABG to left anterior descending artery and/or its diagonal branch for single-vessel coronary artery disease (group 2). The copper-EDTA complex was retained in 0.7 position from the anode after 12 h and, after 24 h, the position shifted to 0.8-0.9 from the anode. Fish exposed to RD for 24h showed reduction on superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities, and increased glutathione (GSH) content. Imaging studies, either CT temporal bones or MRI of the internal auditory canals without gadolinium, and genetic testing, in particular for connexin 26, connexin 30, and Pendred syndrome, are the most useful diagnostic tests. The frequency of cognitive dysfunction in elderly Sri Lankans with type 2 diabetes mellitus. Inhibiting Solid Tumor Growth In Vivo by Non-Tumor-Penetrating Nanomedicine. Dispensing of fluticasone propionate/salmeterol combination in the summer and asthma-related outcomes in the fall. Although both anodal and cathodal currents were effective, the experiments with two electrodes of different areas revealed that cathodal stimulation exerted stronger effect.

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To assess role of some inflammatory mediators in patients with primary and recurrent lumbar disc herniation. Yet, to our knowledge, no large prospective study has examined the relationship across the lifespan. Cochrane reviews of educational and self-management interventions to guide nursing practice: a review. Recognition of high palatal vault in children suffering from AOM, in the presence of other known risk factors, may guide health care professionals to identify an otitis media prone patient and aid in prevention of recurrence. The fiber that is investigated shows a large modal birefringence peak value of 0.016 at an operating wavelength of 1.55 microm and exhibits highly tuneable dispersion with multiple zero dispersion wavelengths and also large normal dispersion. However, these two domains are clearly separated in HPLC due to the opposite polarity of the mobile phases used for each method. omanensis are generally similar to those of a number of other studied sharks. crispatus ZJ001 were compared to Lactobacillus acidophilus ATCC 4356 from the same genus which also produces the S-layer proteins.

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A homologue of Bombyx p260/270, mouse fatty-acid synthase (FAS), was shown to be expressed specifically throughout most of the central and peripheral nervous system in mouse embryos. Preclinical data conducted with different cell lines expressing human CRF receptors and in Wistar and Sprague-Dawley rats indicate that NBI-34041 is effective in reducing endocrine responses to pharmacological and behavioral challenge mediated by CRF(1) receptors. We experimentally demonstrate resonant coupling between photons and excitons in microcavities which can efficiently generate enormous single-pass optical gains approaching 100. Consequently, we now demonstrate here that the capacity to mount a peptide-specific cytotoxic T-lymphocyte response following transcutaneous immunization using imiquimod as adjuvant is severely impaired in mast-cell-deficient mice. Long-term survival in patients with lymph node-positive bladder cancer who undergo cystectomy suggests a therapeutic role for lymphadenectomy. Our in vitro results indicate that human adult CNS-derived oligodendrocytes are relatively resistant to NO-mediated damage. Also recent failures in the development of a vaccine against HIV may at least in part be attributed to induction of enhanced susceptibility to infection. Strikingly, the number and type of GT6 genes varied widely from species to species, even within phylogenetically related groups. Case reports, scientific literature, and the recommendations of expert professional groups.

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Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target. Immunohistochemical staining was performed to determine the presence of FasL in cross-sections of those discs. Outbreaks have occurred in Malaysia, Singapore, India and Bangladesh, and a putative Nipah virus was also recently associated with human disease in the Philippines. He had been repeatedly hospitalized owing to pneumonia recurring in the left lower lung field and had a 7-day history of hemoptysis at the age of 11. Despite the recent speech by shadow secretary Andrew Lansley at the Conservative Party conference, the electorate remains unclear about Tory policy on the NHS.

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