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Baclof (Baclofen)

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Baclof is a muscle relaxant. It works on the brain and spinal cord to relieve muscle stiffness or spasm maintaining the strength of the muscles. This relieves pain and improves movement of muscles.

Other names for this medication:
Bacfen, Baclof, Baclofen, Bacmax, Chinofen, Liofen, Parafon, Riclofen, Spinofen, Spinospas, Tefsole

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Also known as: Baclofen


Baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine. Baclofen does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects. Baclofen may also be used to relieve other conditions as determined by your doctor.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain baclofen. It may not be specific to Baclof. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, or do not take it longer than your doctor ordered.

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For muscle relaxation: For oral dosage form (solution): Adults and children 12 years of age and older—At first, 5 milliliters (mL) three times a day for 3 days. Your doctor may increase your dose by 5 mL every 3 days as needed and tolerated. However, the dose is usually not more than 80 milligrams (mg) per day (20 mg four times a day). Children younger than 12 years of age—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults and teenagers—At first, 5 milligrams (mg) three times a day. Your doctor may increase your dose by 5 mg every 3 days until the desired response is reached. However, the dose is not more than 80 mg per day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Baclof and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Baclof are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of baclofen oral liquid in children younger than 12 years of age. Safety and efficacy have not been established.

Appropriate studies have not been performed on the relationship of age to the effects of baclofen tablets in the pediatric population. Safety and efficacy have not been established..

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In this study, we searched for possible changes in the expression of the two central 5HT receptor subtypes: 5HT-1A and 5HT-1B, both participating in the regulation of brain 5HT transmission. The numbers of NGF, BDNF and NT-3 immunopositive neurons and their optical densities all increased in the lesion-induced cord. Diagnostic accuracy remains high despite the presence of heavy calcifications but is associated with an increased rate of nondiagnostic segments. The document produced by the Task Force is intended for healthcare professionals and deals with the role of physical activity in the prevention and treatment of cardiovascular diseases. This study investigated sample sizes required to demonstrate reduction of brain atrophy using three outcome measures prilosec dosage infant in a parallel group, placebo-controlled trial for secondary progressive MS (SPMS). There is an established need for vision-specific age-appropriate PROMs for use in paediatric ophthalmology, but there are significant practical and methodological challenges in developing and applying appropriate measures. Pretreatment with a Caspase-3 inhibitor or antioxidant, N-acetyl-L-cysteine (NAC), significantly attenuated MF-induced cell growth inhibition and cell death. SBS was significantly improved with curing of the coat and adhesive separately, while it was not adversely affected when the coat and adhesive were cured simultaneously. The anterior cruciate ligament (ACL) fails to heal after traumatic rupture. A high proportion of cells were still viable after 80 days of storage at refrigerated temperatures.

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Collagen cross-linking within the bone results in impaired plasticity and increased stiffness. Deformation induced directional amorphization in Zr2Ni systems: a remedy for the mechanical failure of nano-crystalline alloys. We experienced that two Japanese women diagnosed with syringoma, confirmed by a punch biopsy, were successfully treated with fractional resurfacing. The electrolytes are found to be highly zinc calcitriol drug class ion-conducting with very favorable physicochemical and electrochemical characteristics. In addition, different components have different implications for the amount and kind of care resources needed. Iron-Catalyzed Mild and Selective Hydrogenative Cross-Coupling of Nitriles and Amines To Form Secondary Aldimines. Abatacept delayed progression of UA/very early RA in some patients. The major role in the pathogenesis of most precancerous lesions can be accounted to high risk human papillomavirus.

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Detection of VVEQMCTTQYQK was more sensitive than for the derivative with phenylisothiocyanate (PITC) because of decreased ionization efficiency of the PITC-derivatized peptides. Sequencing-based typing reveals six novel MHC class I chain-related gene B (MICB) alleles. Many children do not receive comprehensive asthma treatment that includes management of allergies and education on avoidance of household allergens. Late potentials are the special case of high frequency signals appearing in the terminal QRS. The role of the orbicularis oculi muscle and the eyelid crease in optimizing results in aesthetic upper blepharoplasty: a new look at the surgical treatment of mild upper eyelid fissure and fold asymmetries. In order to improve the mechanical properties of SBMA hydrogels, linear polySBMA was introduced to the network of chemically cross-linked polySBMA gels, creating a chemical-physical double network (DN) with both chemical and physical cross-links. Masked hypertension is frequently underestimated in OSAS and is nearly always present when clinic BP is above 125/83 mmHg. Standardized retreat sites can provide robust experimental data on the effects of landscape-scale attributes on retreat site selection, revealing interspecific divergences among sympatric taxa that use similar habitats. HIV-infected study children were initiated on stavudine/lamivudine is hydroxyurea a chemotherapy drug /NVP as a fixed dose combination.

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One of the current problems of micro-optofluidics is the choice of a suitable liquid with a high refractive index (RI). In men with prostate cancer, the PSAV was significantly greater than in those without prostate cancer and correlated with pathologic stage and Gleason score but not with prostate volume. Design, synthesis and anticancer activity of nitric oxide donating/chalcone hybrids. To investigate self-administered vaginal swabs for assessing prevalence and correlates of carcinogenic human papillomavirus (HPV) infection in rural Rakai, Uganda. Induction therapy with corticoid pulses for treatment of temporal arteritis. Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms.

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Here, we describe a simple method combining reverse transcription (RT)-PCR and denaturing gradient gel electrophoresis (DGGE) for rapid detection and characterization of T-cell clonality. All respondents were interviewed at their homes or offices by a team of interviewers. A previous small study suggested that Brain Network Activation (BNA), a novel ERP-based brain network analysis, may have diagnostic utility in attention deficit hyperactivity disorder (ADHD). In vitro endurance of the 3DF disc was examined under long-term alternating stresses, and the in vivo animal tests were conducted in the intervertebral lumbar discs at L5-L6 excised from baboons and replaced with the lumbar 3DF disc. the cornea and the crystalline lens) supported the validity of our method and its findings. Specific injuries vary by sport and can involve various structures, depending on the mechanism of injury. will flagyl treat a bladder infection Fourier transform microwave spectroscopy and molecular structure of the 1,1-difluoroethylene-hydrogen fluoride complex. The results regarding the attained DBP level is somewhat complex, since middle-aged people with diastolic hypertension and pre-existing CVD may have increased CVD mortality if their DBP is lowered drastically to a very low level. Extraction was carried out in petroleum ether, chloroform, alcohol, hydroalcoholic, aqueous, and phytochemical constituents present in extracts were detected by different chemical tests.

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Methods and tools for mining multivariate temporal data in clinical and biomedical applications. This may require urgent surgery to replace the conduit or to perform a cavo-pulmonary shunt but as an alternative, transcatheter stent placement can be used with equal effectiveness and with a low risk of complications. We calculated the Spearman correlations comparing intakes of specific fatty acids as percent of total fat intake, adjusted for energy intake, as measured by FFQ, with the percentage of the corresponding fatty acid in adipose tissue. Generation and characterisation of stable ethanol-tolerant mutants of Saccharomyces cerevisiae. To increase the proportion of patients having an LP for a suspected CNS infection for whom the appropriate samples are taken. Analyses were performed in large clinical samples with high base rates of major depression and a broad range of depressive symptom severity. While the fate of the chemically complex coastal DOC reservoir has long been recognized as a critical feature of the global carbon budget, it has been problematic to identify both the compounds that serve as major conduits for carbon flux and the roles of individual bacterioplankton taxa in mediating that flux.

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