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Bacsul (Trimethoprim)

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Bacsul is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Other names for this medication:
Bacterol, Bactipront, Balkatrin, Biseptrin, Colizole, Comox, Dotrim, Epitrim, Exazol, Infectrin, Irgagen, Kanprim, Kombitrim, Megaset, Momentol, Primadex, Primazole, Sanprima, Septrin, Sigaprim, Spectrem, Sulfa, Sulfamethoxazolum, Sulfametoxazol, Sulfoprima, Sultrim, Tabrol, Trimecor, Trimesulf, Trimol, Trisulin, Urisept

Similar Products:
Propecia, Naprosyn, Geodon, Inderal, Priligy, Zyloprim

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Also known as: Trimethoprim


{name} contains a combination of sulfamethoxazole and trimethoprim. Sulfamethoxazole and trimethoprim are are both antibiotics that treat different types of infection caused by bacteria.

{name} is used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.


This medication is given by injection into a vein as directed by your doctor. It is given by slow infusion over 60 to 90 minutes. Dosage is based on your medical condition, weight, and response to treatment. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or worsens.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Bacsul are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency), history of blood disorders caused by trimethoprim or sulfa medications, vitamin deficiency (folate or folic acid), severe allergies, asthma, decreased bone marrow function (bone marrow suppression), a certain metabolic disorder (G6PD deficiency), underactive thyroid, mineral imbalances (such as high level of potassium or low level of sodium in the blood). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level. Patients with AIDS may be more sensitive to the side effects of this drug, especially skin reactions, fever, and blood disorders. This medication is not recommended for use during pregnancy especially near the expected delivery date because of possible harm to the unborn baby. Consult your doctor for more details. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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Monthly prescribing data (July 1996-December 2005) were obtained from a national claims database, and yearly data (2001-2006) from a GP-patient encounter database. During the viewing of moving objects, however, errors in binocular fixation are much larger. Ketamine hydrochloride, in contrast, arrested spontaneous muscle contractions, implying that it did not directly affect the neuromuscular synapse. Glutamate binding was not altered in animals from the Lister strain. There was no evidence of competition for glucuronidation capacity or other metabolic interactions. Marrow transplant for acute nonlymphoblastic leukemia in first remission: a follow-up. The mitral valve was the site of infection in seven of the patients. LLC-MK2 cells were found to be the most sensitive, although primary and secondary human-embryo-kidney and primary calf-kidney cells could also be used. In their acute experiments on 86 rabbits the authors have established that the intravenous administration of nalorphine and naloxone produces a marked therapeutic effect only during the early period of experimental traumatic shock.

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Hepatitis IA and CF antibodies persisted in human subjects for at least 7 hr after hepatitis A virus infection. Similarly, the relationships between the cross-sectional diameters of the spinal canal, the subarachnoid space, and the spinal cord assume a great deal of significance when evaluating patients with signs or symptoms of spinal stenosis. Furthermore, 2-4-fold increases in pGH deposition were also found in various tissues of animals treated with pGH-antibody complexes over that of respective tissues of animals receiving free pGH. Structure-activity relationships of oral organosiloxanes on the male reproductive system. Two types of multinucleated giant cells were observed in periapical granulomas--the foreign body type and the Touton type.

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Immunization with Flexibacter maritimus has not been investigated, and fish surviving a natural infection appear to remain equally susceptible to the disease during subsequent outbreaks. Multiple misdiagnoses of tuberculosis resulting from laboratory error--Wisconsin, 1996. An autopsy case of primary aortoduodenal fistula complicated by both gastric carcinoma and acute gastric mucosal lesions. Intracytoplasmic hydrocarbon inclusions were documented by electron microscopy with chemical identifications obtained by gas chromatography and X-ray diffraction. This study examined the effect of thymus supernatant on the ability of bone marrow cells from senescent mice to home to the thymus.

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Incorporation of 1-C14-palmitic acid into liver lipid fractions of intact animals and following partial hepatectomy. The growing rate of the ossification was calculated in 13 cases of symptomatic OPLL which we have followed up radiologically for more than 2 years. Indeed in the hypertensive elderly, unlike in the normotensive one, no variations of autacoid production occur during the adrenergic activation. We conclude that antibacterial therapy is necessary in the management of Lyme disease, especially after the administration of corticosteroids. It was then possible to determine the percentage of nitrous oxide replaced by nitrogen by measuring the refractive power of the mixture. The mitochondrial fraction of the liver accumulated the isotope in time. To lay the foundation for proper physical and psychological development of children is one of the stated objectives of Integrated Child Development Services Scheme, which is operational in India since 1975-76. Therefore, changes in lung mechanics caused by one-lung ventilation were measured and compared with those previously seen during pulmonary edema. Contributions of projective tests to problems of psychological diagnosis in mental deficiency. Genotyping for HLA-DR by PCR-SSP is a rapid and accurate matching technique suited for clinical application.

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Radioimmunoassay of plasma cortisol is now generally available and is the assay method of choice, but because of the episodic nature of its secretion, random values of plasma cortisol must be interpreted with great reservation, and even the comparison of morning and evening values in assessing circadian rhythmicity is not often helpful. Ceroidogenic activity of hemolyzate in rats fed with diets facilitating autooxidation. After 6 months the patient was still asymptomatic and a treadmill exercise test showed no signs of ischemia. We hypothesized that the elderly would exhibit an impaired functional capacity at altitude, with increased myocardial ischemia compared with sea level (SL). These phenomena seemed to be closely related to the otoconial dynamics which may regulate calcium ion homeostasis of the endolymph. When cells are grown at 46 degrees they only contain TSaseA activity. In mice, IL-6 is required for development of B cell tumors upon infection with a retrovirus expressing the myc/raf oncogenes. In ill infants treatment of the underlying problem often results in resolution of the thrombocytopenia. These include, but may not be limited to, neuroendocrine dysfunction, neuropsychological effects, and ocular and pulmonary dysfunction. Ischemia was induced by four-vessel occlusion for 30 min following reperfusion in rats.

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However, most bacterial strains readily translocated to the MLN. Age of referral, distribution within the family, sex and sources of referral are indicated and discussed. This differs from literature reports of massive transfusion requirements and two cases of exsanguination following resection. The level of enzyme activity has been shown to be reduced to about half the normal value in erythrocytes of two patients from a family with AIP. Since the spectral profiles of the ECFP and EYFP color variants are distinct and non-overlapping, these two reporters can be co-visualized, and are therefore ideal for in vivo double-labeling or fluorescent energy transfer analyses. The data suggest that insulin exerts its antilipolytic effects via mechanisms which are different from those involved in the effects of prostaglandin E2, N6-phenylisopropyladenosine and nicotinic acid. Exogenous glycine betaine at a concentration as low as 1 mM was found to stimulate the growth rate of Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae in media of inhibitory osmotic strength.

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Familial manic-depressive illness with deleted short arm of chromosome 21: coincidental or causal?. The possible role of streptomycin in the post-operative deaths of two patients. Metabolic effects of 2-bromo ergocryptine-methane-sulphonate (CB 154) in the rat. Application of an analytical method to calcium acetylhomotaurinate determination in urine. In another, fluorescein angiography showed a reticular pattern that was not apparent by ophthalmoscopy. A case of transient cortical blindness due to reversible ischemic neurological deficit (RIND) after caesarean section under lumbar anesthesia. Phaeochromocytomas discovered during coronial autopsies in Sydney, Melbourne and Auckland. The changes that renal failure makes in drug elimination were equally presented, having been pointed the modification of protein binding, volume of distribution, and hepatic elimination.

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Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo. To improve control over the shape of the lenticule, we have developed a cornea press which restores normal hydration and dimensions to the donor tissue by mechanical dehydration. These findings suggest the possibility that oxidative stress may be related to the development of diabetic complications. Instead, it appearstheat the effect of acetazolamide is due to a direct interaction with a membrane component involved in the coupled influx process. The rules of drug taking: wine and poppy derivatives in the ancient world. G17 induced p38 kinase activity at doses and with kinetics similar to those observed for Akt induction. A new deoxygenation reaction of an aromatic heterocyclic N-oxides. Versatile capillary electrophoresis instrumentation that permits the rapid and precise translation of a laser fluorometric detection zone along the capillary wall has been used to examine the factors which cause band broadening during size-selective separations of DNA fragments. Isolated tuberculous monoarthritis mimicking oligoarticular juvenile rheumatoid arthritis. Histopathological changes caused by stress during catching and transport were examined in four fish species, the common carp (Cyprinus carpio), the Japanese coloured carp (koi, the coloured variant of the Asian carp, Cyprinus carpio haematopterus), the European eel (Anguilla anguilla), and the African catfish (Clarias gariepinus).

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The resting membrane potential was decreased by pentobarbital only to a small extent (less than 15 mV) in both end-plate and non-end-plate regions. Growth rate modulation of four aminoacyl-transfer ribonucleic acid synthetases in enteric bacteria. The cDNA for XPMC2 was previously shown to rescue mitotic catastrophe in mutant S. Dual immunohistochemistry was employed to examine the role of gonadal steroids in determining sexual differences in the expression of Fos and its related antigens (FRA) in tuberoinfundibular dopaminergic (TIDA) neurons located in the dorsomedial (DM-) and ventrolateral (VL-) subdivisions of the arcuate nucleus (ARC). Problems with food packaging: are we promoting mealtime dependence in the elderly?. This review describes the existence of a phenomenon, sequential separation of centromeres, in mitotic cells of various species including both animals and plants. Effect of diet and sulfonylurea drugs on insulin resistance and insulin-receptor function.

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In vitro polyoma DNA synthesis: inhibition by 1-beta-d-arabinofuranosyl CTP. Enhanced detection of reversible perfusion defects by Tc-99m sestamibi compared to Tc-99m tetrofosmin during vasodilator stress SPECT imaging in mild-to-moderate coronary artery disease. In twenty-five animals (Group II ventolin hfa dosing instructions ) the left buccal pouch was painted three times weekly with a 0.5 per cent solution of 9,10-dimethyl-1,2-benzanthracene (DMBA) in heavy mineral oil. Residues in transmembrane helical domains (TMs) 3, 5, 6, and 7 predicted by molecular modeling to be involved in ligand recognition were replaced with alanine and, in some cases, by other amino acids. Increase in the heart rate-corrected QT interval in children of anti-Ro-positive mothers, with a further increase in those with siblings with congenital heart block: comment on the article by Cimaz et al. The high prevalence of chronic illness and functional limitation among older persons underscores the need for strategically directed health and social services.

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Resistance in the denervated paws was less than in the innervated paws at all temperatures. It was 12.3 times greater for children younger than 1 year, 7.2 times greater for those 1 to 2 years old, and 3.8 times greater for those 2 to 3 years old. The distribution and localization of a glioma-associated antigen defined by monoclonal antibody 81C6 has been examined using human cultured cell lines and tissues. Kinetics of pulmonary platelet deposition and clearance during thrombin-induced microembolism in rabbits. To describe the learning curve in prostate seed implantation, according to the experience with two groups of 100 patients. Collections were made from both traditional and commercial cattle at each altitude. Despite an initial complete clinical response to VP-16 and carboplatin, residual tumor was noted in the cervical cone biopsy specimen and she was treated with external-beam irradiation and cesium implants. Correlation with the number of skin lesions and recovery after corsticosteroid therapy. Western blots of bovine medulla tissue homogenates showed the principal adrenal medullary immuno-reactive species to have a higher molecular weight (50 kDa) compared to StAR protein (30 kDa). Based on this analysis, recommendations for future steps to be taken by researchers, adolescent health practitioners, and the manufacturer of the female condom are presented.

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The recent ability to diagnose asymptomatic endometriosis has produced dilemmas, particularly with respect to the need for treatment. Compatibility of cisatracurium besylate with selected drugs during simulated Y-site administration. The amino acid sequence obtained corresponded very closely in part to the N-terminal amino acid sequences of two polypetides within the complex. If it exceeded 2, working conditions at the bay were considered unfavourable. The effect of parity on decidual, placental and fetal weight in the mouse. The MSE transient behavior for this kind of filters is also presented for the first time.

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The results in previous human studies can be alternatively explained by the long-term nonspecific effect of enteral nutrition on gut adaptation. These novel characteristics of TetC thus differ significantly from results obtained from hitherto analyzed catechol 1,2-dioxygenases and chlorocatechol 1,2-dioxygenases. An abdominal mass was palpable in all five cats, but the mass could be localized to bowel in only two cats. Whole-body protein kinetics in children with kwashiorkor and infection: a comparison of egg white and milk as dietary sources of protein. The results suggest that the number of nodal mast cells may be a readily quantitated host response of prognostic value in carcinoma of the breast. Detection by means of cell fusion of macromolecular synthesis involved in the reconstruction of the nuclear envelope in mitosis. In hapatomas formed spontaneously without cirrhosis at Swiss mice numerous globular corpuscules of eosinophil character were found.

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This approach is suitable for the systematic study of other procaryotic or eucaryotic organisms. Induction of endothelial cell decay-accelerating factor by vascular endothelial growth factor: a mechanism for cytoprotection against complement-mediated injury during inflammatory angiogenesis. In such conditions only parenteral nutrition can provide adequate nourishment and prevent malnutrition. Three systems were built that represented three methods of resistive exercise. The ability of each of the models to describe and incorporate such physiological processes as protein binding, precursor-metabolite relations and hepatic zones of elimination, capillary recruitment, capillary heterogeneity, and intrahepatic shunting is discussed. The remaining three were hitherto unpredicted five-membered ring compounds, i. During the second cycle of HF feeding (weeks 16-25) the HF-diet further increased body weight gain in both male and female rats compared with CH-fed controls. Furthermore, it was shown that in guinea pigs the increased level of lipid peroxides and that in rats the increased activities of antioxidative enzymes and the increased contents of the antioxidants were synergistic following exposure to the combined gases.

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Kinetics of adenosine triphosphate synthesis in bovine heart submitochondrial particles. Additions and changes to the basic regulations for a new grouping of patient contingents being served by outpatient tuberculosis institutions. In order to evaluate the setting expansion of the stones and the pressure against the impression, stones were poured in other impressions that were taken from a cubic master model. Tumor-associated proteolytic factors uPA and PAI-1 in endometrial carcinoma. Furthermore, our data indicates that repeat throacotomy because of bleeding or tamponade early after sustaining a perioperative infarction will adversely affect the outcome of that infarction.

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Unexpectedly, we found IgG antibodies with specificities tricor dosage for cardiolipin and mitochondrial antigens to be significantly higher in healthy mink than in ADV-infected mink. In this 37-year-old man with a complaint of occasional nausea, vomiting and abdominal pain, intravenous cholecystography combined with tomography demonstrated a normal size gallbladder with many thin septa. 92, 11312-11316) we show conclusively that ascorbate oxidation by APX is not inhibited by SA (10 mM), but that SA is a slow reducing substrate of this enzyme. Mutations of residues in loop L1 (Gly-12 and Gly-13), in loop L2 (Thr-35 and Asp-38), and in loop L4 (Gln-61 and Glu-63) influence the reaction in different ways, but all of these mutant p21 proteins still form complexes with GAP. The availability of biochemical and molecular genetics techniques has allowed the discovery of complex signaling networks which are essential for Dictyostelium development and are also conserved in other organisms. The PCP in patients with AIDS may require more prolonged therapy for complete resolution of this pneumonic process. Tetrahydroisoquinolines and the catecholamine-binding granules of the adrenal medulla.

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The present work deals with the treatment of cutaneous leishmaniasis using surgical techniques from the onset. All three harvests were evaluated with sheep and the last two also with goats, using six animals each time. There was no demonstrable effect on holding power when screws were inserted with or without tapping. Raphe origin of serotonergic what class of medication is risperdal nerves terminating in the cerebral ventricles. However, lactate dehydrogenase activity was not affected by pyruvate feeding in comparison to the glycolate-treated group. No definite pattern was apparent for estradiol-17beta or estriol. The ability to assess receptor-specific endocytosis has led to the recognition of Fc-receptor dysfunction in certain autoimmune diseases. In contrast to the rapid excretion of ethylmorphine and codeine, pholcodine showed positive results for opiates 2-6 weeks after intake when the urines were analysed with the RIA-method. Toxin entered cells after incubation at 25 degrees C but not at 20 degrees C, although toxin binding was the same at the two temperatures. Cranial CT proved exceptionally accurate in detecting and localizing cerebral neoplasms in children, with only one false negative case in 40 tumors.

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Senile dementia was diagnosed in 24 subjects per 1000 under 75 years and 109 per 1000 over that age. There was no difference in response times for the up and down eye-movements when the fixation and target distances were the same. We describe three experiments testing treatments to promote the performance of health-protective dental behaviors. We believe that this phenomenon is occurring more frequently than is being reported. Patients with previous CABG or a left main coronary artery disease were excluded. Further work is still needed to determine whether tenormin drug class the findings are specific to panic disorder. Exemption from compulsory wearing of seat belts--medical indications.

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A column-switching high-performance liquid chromatographic method was developed for the determination of oxiracetam in plasma and urine. The unique nature of the target populations, the scope of side effect evaluation, and the potential duration of treatment must be considered in the design of these trials. Views of mental illness in Morocco: Western medicine meets the traditional symbolic. Anticipatory pursuit is sometimes attributed to cognitive expectations about future motion and other times to the habitual repetition of previous pursuit responses. Incubation units (150 eggs/unit) of each trial were distributed randomly in the lighted or nonlighted incubators. After a 12 month follow-up no recidive pneumothorax occurred and the general conditions of the patient were good. The corresponding figure for cefaclor and cefuroxime was 2.56 micrograms/ml. Allelic complementation between MHC haplotypes B(Q) and B17 increases regression of Rous sarcomas. Studies were performed on the behavior of cutaneous delayed-type hypersensitivity (DTH) in guinea pigs in which macrophage disappearance reaction (MDR) was induced.

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Chemokine receptor CCR5 genotype influences the kinetics of human immunodeficiency virus type 1 infection in human PBL-SCID mice. Overall agreement between duplex scanning and IADSA for popliteal and crural arteries was moderate (kappa 0.47, 95 per cent confidence interval (c.i.) 0.39-0.55) with best agreement within the popliteal and proximal tibial arteries. In this report, we describe a case of aortic intramural hematoma after balloon angioplasty of a recoarctation. Regression of the vascular tunic of the lens occurs during the second half of fetal life and is nearly completed in the first postnatal days. Irregular deposits of immunoglobulins and complement were demonstrated in the vessel walls and in luminal thrombi and suggested an immune-complex origin. Convulsive effects of thiophene, a heterocyclic hydrocarbon: behavioral, electrographic and c-Fos immunocytochemical studies. Gastrointestinal manifestations of brucellosis in Saudi Arabian patients. coli cultures before estuarine exposure were reduced to minimize sublethal stress, and nonselective or resuscitative enumeration techniques were employed to maximize recovery of stressed cells. There was little difference in generalization scores for the remaining subjects.

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