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Bactrizol (Trimethoprim)

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Bactrizol (generic name: Co-trimoxazole; brand names include: Septra / Ciplin / Septrin) is a combination of two antibiotics (trimethoprim and sulfamethoxazole) used to treat a wide variety of bacterial infections.

Other names for this medication:
Bacsul, Bacta, Bactelan, Ciplin, Gantrisin, Gentrim, Groprim, Ifitrim, Infectrin, Kombitrim, Metoxiprim, Metrim, Neotrim, Nopil, Novidrine, Onetrim, Septra, Spectrem, Sulfoid, Sultrim, Suprim, Sutrim, Trisulfose, Zaxol, Zoltrim

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Also known as: Trimethoprim


Bactrizol is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Bactrizol tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Bactrizol DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


Prescribing Bactrizol (sulfamethoxazole and trimethoprim) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Bactrizol should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency (e.g., the elderly, chronic alcoholics, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states) and to those with severe allergies or bronchial asthma.

Hematological changes indicative of folic acid deficiency may occur in elderly patients or in patients with preexisting folic acid deficiency or kidney failure. These effects are reversible by folinic acid therapy.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Bactrizol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Bactrizol if you are allergic to Generic Bactrizol components. Do not take Generic Bactrizol if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Bactrizol can harm your baby. Do not take Generic Bactrizol if you have anemia. Generic Bactrizol can't be given to children younger than 2 months old. Avoid exposure to sunlight, sunlamps, or tanning beds while taking Generic Bactrizol. Be careful with Generic Bactrizol if you have kidney or liver disease, folic acid deficiency, asthma or severe allergies, AIDS, glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency); if you are malnourished. Be careful with Generic Bactrizol if you take seizure medication such as phenytoin (Dilantin); diuretic (water pill); blood thinner such as warfarin (Coumadin); methotrexate (Trexall, Rheumatrex); methotrexate (Trexall, Rheumatrex); or an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace) or trandolapril (Mavik). It can be dangerous to stop Generic Bactrizol taking suddenly.

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Effect of temperature on the development of prepupa and pupa of the rat flea, Xenopsylla cheopis Rothschild. Thrombocytes showed a steady drop after infection to the time of death of the animals. Right-angled narrowing of the distal oesophagus secondary to carcinoma of the tail of the pancreas. Possible effects of antioxidant status on increased platelet aggregation in childhood iron-deficiency anemia. The data on intensive care units patients and from special groups of patients, such as those undergoing dialysis, organ transplant recipients, or cancer patients receiving chemotherapy, should also be made available to practicing physicians. Treatment of depressive states with special consideration of tofranil, a new antidepressant. Chemical data on human epidermal keratinization and differentiation. Comparison of costs between video-assisted thoracic surgery (VATS) and thoracotomy. The value of postadjuvant chemoimmunotherapy after metastasis resection is being investigated in numerous studies at present.

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