Understanding the basis for individual differences in nicotine kinetics and metabolism, and linking these differences to pharmacodynamic studies, may provide important clues for the prevention and treatment of nicotine and possibly other drug addictions. Analysis of postural sway using entropy measures of signal complexity. iNOS was localized in the cytoplasmic vesicles and endoplasmic reticulum of vascular endothelial cells, vascular smooth muscle cells and cardiomyocytes after endotoxin administration. The serum polyol pattern and the urinary polyol excretion in diabetic and in uremic patients. Two out of three collagen disease cases were positive to 2 antibodies among the measured 3 IgG antibodies. Interference of tris(hydroxymethyl)aminomethane with structure and function of Golgi membranes. This high and sustained level of egg deposition requires that oogenesis be stimulated to provide the necessary mature oocytes. Periarticular soft tissue conditions causing pain in the shoulder.
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Shape completion time depends on the size of the occluded region. Salvage surgery at the hip to improve sitting posture of mentally retarded, severely disabled children with cerebral palsy. This prospective study was undertaken to determine the percentages of patients experiencing different types of sexual dysfunction after successful antidepressant treatment with standard doses of fluoxetine. Atypical astrocytes and Rosenthal fibers in a case of amyotrophic lateral sclerosis associated with a cerebral glioblastoma multiforme. Sulphydryl addition compounds of some quinones and related substances in their action on the growth of normal cells. The arrangement is designed specifically for measurement of coronary vessels, but it can be adapted to other structures. Ki-ras codon 61 mutations were detected in 22 of 25 tumor samples without differences among strains. In addition, treatment of bovine leukocytes with protease K eliminated subsequent binding of leukotoxin, suggesting that there is a protein on the leukocyte surface that is either a leukotoxin binding site or is required for stabilization of leukotoxin binding.
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Symptomatic heterogeneity, complement analysis and therapeutic trials. Delivery of proteins to the vacuole of the yeast Saccharomyces cerevisiae requires the function of the endosomal syntaxin, Pep12p. As these procedures become more common, we may be exposed to the increasing numbers of patients with this clinical presentation. A model is proposed describing the process of spermatogonial development in the quail. The effect of agents known to release histamine from intact rat mast cells (antigen, compound 48/80, decylamine, the ionophores A23187 and X537A as well as ATP) was studied on the granules. marcescens was grown in another case from the lens solutions and carrying case. Monographs for various types of fish vaccines are now being elaborated. 1) Human trophoblast cells are able to express the iNOS mRNA, hence suggesting a role for NO in placental growth and function.
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Urea treatment preferentially eluted MAbs to discontinuous rather than continuous epitopes, independent of their affinities. Platelet membrane abnormalities in myeloproliferative disorders: decrease in glycoproteins Ib and IIb/IIIa complex is associated with deficient receptor function. Glycogen content was markedly diminished or completely absent, as demonstrated histochemically, both in the morphologically intact and in damaged tubules. This study evaluated the predictive role of fasting serum insulin, body mass index (BMI), and waist-to-hip ratio (WHR) on the development of incident MMS components (diabetes, hypertension, and dyslipidemias) over the course of three years. An investigation of the biological behavior of the sulfur analogue of choline. The outcome of orthotopic liver transplantation (OLTX) in patients retransplanted for severe hepatitis B virus (HBV) in the first allograft has been poor due to high rates of HBV reinfection and even more aggressive disease in the second graft.
In the transmeatal tympanoplasty, the ear canal should permit the use of a speculum large enough to expose the entire perforation. Structural characteristics of the mesenteric vascular bed of the intestines. Intravenous midazolam (Versed Roche Laboratories) is distinguished from diazepam (Valium, Roche Products) by its water solubility, short elimination half-life, and generally short duration of action. Exact mass measurements on-line with high-performance liquid chromatography on a quadrupole mass spectrometer. Some bacterial pathogens have evolved by acquiring pathogenicity islands (PIs), which are clusters of genes encoding virulence traits.
Acute dissecting aneurysm of the aorta after renal transplantation. Molecular determinants of non-specific recognition of delta, mu, and kappa opioid receptors. We propose here a model in which transposable elements are involved in speciation events by their ability to produce irreversible deleterious mutations that promote escape from evolutionary stasis. Burnout and inequity among human service professionals: a longitudinal study. The effect of arginine supplementation on growth hormone release and intestinal mucosal growth after massive small bowel resection in growing rats. Lipid peroxidation was employed as an experimental model to study the antioxidant properties of avarol, a sesquiterpenoid hydroquinone and of its quinone, avarone. Maternal bilirubin, cord bilirubin, and placenta function at delivery and the development of jaundice in mature newborns. There was no significant difference between treatments in the postovariectomy rise in LH. Cluster headache: phospholipid metabolism in polymorphonuclear cells. The hepatitis delta virus (HDV) contributes significantly to the morbidity and mortality of hepatitis B virus (HBV) infection, which is particularly prevalent among intravenous drug users and male homosexuals.
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The occurrence of tumours in F1, F2 and F3 descendants of bd rats exposed to N-nitrosomethylurea during pregnancy. Both the SH2 and SH3 domains of Crk were required for this activity. Differentiated complexes of resort treatment, depending upon the form and severity of clinical sings were elaborated, as well as the possibility of resort therapy in children with cerebral paralysis, complicated by the intracranial hypertensive syndrome. In 30 patients, 52 to 75 years of age undergoing elective orthopedic operations, 10 serial blood samples were obtained in the perioperative period: two samples before skin incision and eight samples after the incision over a time span of 70 hours. In this technique the region of interest is first amplified under mutagenic polymerase chain reaction (PCR) conditions. Here we report the synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid). The women in labour after artificial abortion were older, had during pregnancy more frequently bleeding, gestosis, urinary tract infection. Purification was accomplished by sequential concentration, ammonium sulfate precipitation, lentil lectin affinity chromatography, gel filtration, and reverse-phase high-performance liquid chromatography. The output distribution can also be used as valuable input to the risk management process, because it provides information on probabilities of exposure levels, that can influence the cost-benefit analysis of the risk management process. This strategy minimizes bleeding risks and is associated with an acceptable filter life.
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Significant correlations were found between beta 2-microglobulin concentration and the serum creatinin concentration as well as the creatinin clearance, but not between beta 2-microglobulin and the gestosis index. Induced fluid movement within a giant ovarian cyst demonstrated by echo-planar imaging. These data indicate that the switch affects codon-anticodon arrangement and proper selection of tRNA at the ribosomal A site, and that the switch is a fundamental mechanism in all ribosomes. Three rats of six males, surviving 22 to 27.5 months after one or two intragastric doses of the monoester pyrrolizidine alkaloid, heliotrine (230 mg/kg body weight), and pretreatment with nicotinamide (350 mg/kg body weight) by pretreatment with nicotinamide (350 mg/kg body weight) by i.p. Furthermore, their isogenic nature was confirmed by cloned transgenic homozygous offspring produced via another step of parthenogenic reproduction of the isogenic homozygous transgenic fish. Use of nitrofurantoin macrocrystals after transurethral prostatectomy. Latex agglutination assay of human immunoglobulin M antitoxoplasma antibodies which uses enzymatically treated antigen-coated particles. The prevalence of diabetes will remain relatively constant at approximately 1 million patients in younger populations (less than 45 yr old) through the middle of the next century. Treatment was by surgical excision of the tumor and the involved tracheal ring.
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The calcium antagonists (calcium entry blocking drugs) are a distinct group of compounds that interfere with the normal transmembrane flux of extracellular calcium ions on which vascular tissue depends for contraction or impulse generation. Annual meeting of the Hungarian Biochemistry Society, Drug Biochemistry Section. Interaction of competitive antagonists: the anti-curare action of hexamethonium and other antagonists at the skeletal neuromuscular junction. Prevalence and significance of anti-HBc IgM (radioimmunoassay) in acute and chronic hepatitis B and in blood donors. Neuroendocrine histopathological findings in post-traumatic apallic syndrome. A number of investigational therapies are being performed nationwide in an attempt to improve the prognosis for children with neuroblastoma.
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The Pappenheimer equivalent pore radius estimate of 30 A and the Karnovsky interendothelial 40 A slit width are both defective in explaining the experimental data. Differential diagnosis of papilledema in malignant hypertension and choked disk. Although paracetamol potently reduces pain and fever, its mechanism of action has so far not been satisfactorily explained. The in situ phosphorylation of microtubular protein in brain cortex slices and related studies on the phosphorylation of isolated brain tubulin preparations. Ophthalmologists now have laser and surgical treatment modalities available that can significantly decrease the risk of blindness in the diabetic population. Normal control and irradiated lymphoid cells were treated with rabbit anti mouse IgG fluorescein conjugated serum and the fluorescein positive cells compared. Mary Clay offers a guide to the essential principles as a teaching aid for all caring staff. Nippostrongylus brasiliensis: intestinal goblet-cell response in adoptively immunized rats.
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In vitro inhibition of nitrogen mustard efficacy by postincubation of treated cells in serum protein. The author describes and illustrates with case reports a successful Newport News program in which physicians, hospitals, paramedics, and local government services work together. Comparison of clinical efficacy and adverse effects between extended-release felodipine and atenolol in patients with mild and moderate essential hypertension. The identification of thyrotropin releasing hormone (TRH) in hypothalamic and extrahypothalamic loci of the human nervous system. The frequency of the transfer of R plasmids to Escherichia coli K-12 C 600 rif varies within 0.6 X 10(-5) and 0.7 X 10(-3) per donor cell. Antibodies to the core protein of lymphadenopathy-associated virus (LAV) in patients with AIDS. These results indicate that resistance training produces functional adaptations of the neuroanatomical constraints that underlie the control of voluntary movement. The first cases of Fansidar resistant Plasmodium falciparum infection in Surinam are reported after chloroquine-resistance was reported in 1972.