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Cardizem (Diltiazem)

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Cardizem is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Cardizem is used to treat hypertension, angina, and certain heart rhythm disorders.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Combivent, Thorazine, Abhigra, Claritin, Sustiva, Caverta, Requip

Also known as: Diltiazem


{name} (diltiazem) is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.

{name} is used to treat hypertension (high blood pressure). It may be used alone or in combination with other high blood pressure medications.

{name} is also used to treat chronic stable angina (chest pain) and angina due to coronary artery spasm.


This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Cardizem LA. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended-release tablet, extended-release capsule, or tablet whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 120 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once a day, either in the morning or evening. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed. Children—Use and dose must be determined by your doctor.

For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 180 to 240 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 to 240 milligrams (mg) once a day, either in the morning or at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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The purpose of this study was to characterize the proliferative response of cultured bovine corneal stromal fibroblasts to PDGF isoforms. The effect of this parameter on SEPs in patients with neurologic disorders has not been systematically studied, although it could have a profound impact if SEPs are to be used for prognostication. For each province, the cumulative incidence of mortality from suicide and self-inflicted injuries were calculated by gender and age groups. A new host and site of infection for Myxobolus kisutchi and host record for Myxobolus insidiosus. Treatment of postprostatectomy urinary incontinence with behavioral methods. Fenfluramine at doses of 25 mg/kg induced decreases of plasma LH and prolactin levels in ovariectomized estradiol- and progesterone-treated rats. Comparison of cefamandole and cefazolin during cardiopulmonary bypass. The female patient had frequent contact with the pool water since she often went to the farm to obtain water for domestic animals.

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Calculation of single-ion activities in solutions simulating blood plasma. We describe several experiments using a montage with current sources located at multiple positions and orientations inside a human skull filled with a conductive medium. Characteristics and response to treatment of posttraumatic temporomandibular disorder: a retrospective study. would be helpful in the identification and classification of these unique coccal isolates in ecological and epidemiological studies. We studied primary tumours and 156 lymph nodes from 32 patients with cervical cancer (stage IA2, IB1, and IB2) and 32 lymph nodes from nine patients with benign disease. Neuroendocrine regulation by the Agouti/Agrp-melanocortin system. Information is discussed with attention to vector potential of C.

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In animals, converging evidence--some reasonably well controlled--indicates that REM sleep deprivation probably heightens central neural excitability and increased motivational behavior, but has nuclear or inconclusive effects on learning. Histopathology and immunohistochemistry of human transmissible spongiform encephalopathies (TSEs). Establishing a national traumatic brain injury information system based upon a unified data set. A transient increase in amino acid transport modulated by insulin in differentiating muscle cells. Twenty-nine patients with progressive hormone-refractory metastatic adenocarcinoma of the prostate were treated with daily estramustine phosphate at 10 mg/kg, and I.V. Lower respiratory tract infection in hospitalized children due to respiratory syncytial (RS) virus during a suspected epidemic period of RS virus in Delhi. Immunohistochemical localization of trypsinogen and trypsin in acute and chronic pancreatitis. The technique allows the diagnosis and accurate localization of phaeochromocytoma and is useful in excluding the tumour in patients with essential hypertension.

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A method for the determination of insulin by paper chromatography. The differences in clinical appearance as well as in quantitative and qualitative LP composition between the common type IIA and type IIA-X makes it important to separate these two types of HLP from each other. The human androgen receptor: structure/function relationship in normal and pathological situations. The number of giant or polynuclear cells and the histochemical NADPH-diaphorase activity were not altered. Measurement of the free to total PSA level improves specificity of prostate cancer screening in selected men with elevated total serum PSA levels between 4.0 to 10.0 ng/ml and normal digital examination, and can reduce unnecessary prostate biopsies with minimal effects on the cancer detection rate. The implants were subjected to a macroradiological, a histological-histomorphometrical, and a fluorescence-microscopical evaluation. During further development till hatching the frequency decreased to 7.5 c/min and the amplitude increased to 1.39 mV. Temperature-modulated aflatoxin B1 hepatic disposition and formation and persistence of DNA adducts in rainbow trout. The rationale of this combination is that enrichment of natural surfactant with DPPC and PG strikingly modifies the lin vitro surface properties of the surfactant preparation, reducing surface tension to very low values already at moderate surface compression. The impact of the progressive increase in antibody administration was observed by comparing the first with the last rate images.

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In the developing mouse retina degenerating neurons can be observed initially in the ganglion cell layer followed by a phase of cell death in the inner nuclear layer. Relations among circadian rhythms in serum iron, glucagon and insulin and urinary cyclic AMP excretion differ drastically when diurnally active, nocturnally resting human adults consume all daily food for one week as breakfast only and for another week as dinner only - a finding of interest to diverse fields, e.g., for optimizing certain kinds of therapy or for a better utilization of calories. We present an overview of the most common types of implantable cardiac devices, potential complications associated with them, and recommendations for preoperative evaluation, intraoperative monitoring, and postoperative follow-up. The kinetics of papillotoxic doses of 3H-N-phenylanthranilic acid in rats. Several of these show antiresorptive activity in growing rats as low as 0.001 mg P/kg. rough endoplasmic reticulum, the Golgi complex and secretory vesicles, were stained for PSG. Effect of high calcium diet on cadmium-induced hypertension in rat. On the role of a mutational database in building artificial intelligence models for understanding gene expression. Accommodation was recorded from right and left eyes of visually normal observers in both binocular and monocular viewing. It should be limited, however, only to patients in whom calculi or calcareous material are both demonstrable and inaccessible by any other means or to patients in whom there are discrete areas of distortion, dilatation, or disease predisposing to the formation of stones with stones present.

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Higher level relationships among placental mammals, as well as the historical biogeography and morphological diversification of this group, remain unclear. Different populations of oligoclonal IgG appear to be associated with antibody specificities to different antigenic components of the virus. These properties have so far prevented complete purification and analysis of the constituents of PHF. Hand therapy is the backbone of a treatment program for complex regional pain syndrome. The G250/MN/CA9 antigen was recently explored as a potential marker for RCC. Rhesus monkey fetuses were surgically prosencephalectomized (Type 2) or functionally hypophysectomized (Type 1) at 75 days gestation, then returned to the uterus until elective Caesarean section on day 145--150 (term 167 days). The strategy is demonstrated by ordering Alu-detected NotI fragments in a panel of mouse: human hybrid cells that span the entire long arm of human chromosome 17. Transsphenoidal adenomectomy rapidly reduced serum TSH to normal and restored the euthyroid state with retention of other anterior pituitary functions.

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Anterior segment fibrin clots were formed in rabbit eyes by injecting citrated rabbit plasma. Gravity appears to alter thermoregulation through changes in both the regulated level of body temperature and the rhythmic organization of temperature regulation. Control and analysis of cells by cytogenetic and mass spectrometric methods. No additional focal response was detected over the remaining (ipsilateral) hemisphere for 60 msec after the stimulus. Utilizing patient satisfaction surveys to prepare for Medicaid managed care. A highly conserved 14-amino-acid region of the chicken beta1 integrin chain (beta1chk residues 151-168) hypothesized to be involved in divalent cation coordination was analysed to determine whether invasin uses the same structural determinants as fibronectin (Fn) to recognize receptors. Radiolucent transverse metaphyseal bands of the proximal humerus were considered as abnormal. To predict the outcome after myocardial revascularisation, a clear separation between hibernation and/or repetitive stunning on the one hand and myocardial scarring on the other hand is of importance.

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to survey Auckland general practitioners and evaluate their attitudes and policies toward screening for cervical cancer. CNE-1 cells were infected using either Ad5CMV-p53 or Ad5CMV-B-gal, followed, 24 h later, by HT (43 degrees C x 0-2 h). Mothers in the experimental group remembered receiving more physical comfort measures, emotional support, and advocacy from monitrices compared to control mothers who received intrapartum care from nurses. The measurement of oxygen consumption of Daphnia by a modification of the Cartesian diver technique. Thrombolytic treatment has been shown to accelerate resolution of major pulmonary embolism and lead to a rapid improvement of right-side hemodynamics. Radiation and thermal sensitivities of murine tumor (FSa-II) cells recurrent after a heavy irradiation. Use of antibiotics in pediatric surgery at the University Hospital Center at Yopougon, Abidjan (Ivory Coast). Catheters were in place an average of ten days (range, one to 40 days). Two cases of marrow failure with massive marrow plasmocytosis simulating myelomatosis. Spontaneous rupture of the liver in pregnancy: a report of eight cases.

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Neither the absence of glycosylation nor the presence of atypical oligosaccharides significantly influenced binding of the monoclonal antibody to the cell surface antigen recognized. Present state of scientific works on blood circulation and kidneys in Great Britain. Social medicine evaluation of pre-employment medical screening of civil service candidates. The results obtained do not support the hypothesis that learning ability varies inversely with the concentration of brain 5-hydroxytryptamine. The administration of 6MP surprisingly induced an increment of tumor blood flow in the castrate group. The features in this case suggest that evaluation of fistula hemodynamics is important in determining the overload on the ventricle through the fistula. for five consecutive days with either 50, 100 or 200 mg musk xylene/kg body weight. It is shown that electric stimulation of the muscles leads to a decrease in the content of cholesterol and atherogenic lipoproteins in blood serum and an increase in the tissue cholesterol content. -- The main points of the surgical management are: the age of surgery, the choice of technic (symmetrical or not), the usefulness of a transient overcorrection, and above all the quantative rules for the surgical treatment.

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Describes 2 variants of the disease course in a male patient with bronchial carcinoma and the leading hypotonic syndrome and in a female patient with intestinal carcinoid running its course in combination with the hypertensive syndrome. Stereoselective disposition of flurbiprofen in normal volunteers. Prostaglandin E1 improves hepatic encephalopathy produced by ischaemia-reperfusion liver injury in rats. Despite the long history associated with varicoceles, there remains much controversy regarding their diagnosis and management. Techniques for the assignment of these resonances are presented. Our results suggest that the VSV glycoprotein is synthesized exclusively on membrane polyribosomes, while at least some of the M, N, and NS proteins are made on free polyribosomes.

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16-substituted steroids in the fetus and newborn in pregnancies complicated by toxemias. Characterization of a cytochrome P450 from di(2-ethylhexyl) phthalate-treated rats which hydroxylates fatty acids. An improved microscope for bead and surface-based motility assays. The burst frequency did not differ between lighting treatments, but during each GH surge, IL broilers released a higher GH mass which resulted in higher GH amplitude values. Cytolytic effects may represent an artifact of the in vitro setting where maximum exposure of cells to the drug can be achieved. The unbound fractions of diazepam and salicylic acid were about double in old compared with young healthy subjects whereas they were similar in young and old patients with lowered creatinine clearance.

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Correlation between the sites of mitral annular calcification and conduction disturbances: echocardiographic evaluation. Demographic data, clinical and laboratory characteristics, and rate of tubal rupture were compared. These effects were somewhat less for methotrexate, for which the major side effects were stomatitis and leukopenia, as well as hepatic toxicity reflected by elevated serum glutamic oxaloacetic transaminase levels. Antibody titers to varicella-zoster (V-Z), herpes simplex (HSV) and vaccinia viruses were determined in sera collected in Buffalo, NY, from patients with multiple sclerosis (MS), patients with other diseases, and normal individuals. Current principles of treating gunshot wounds of the joints at the medical evacuation stage. Correlation was made between the CT and bronchographic findings in these 13 lungs. It is consistent with data suggesting that hypometabolism is an independent predictor of surgical outcome.

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The solvatochromic method combined with a multivariate curve resolution-alternating least-squares analysis method has been used to characterize two modified silica surfaces--phenyl bonded and C18 bonded silica in mobile-phase mixtures of methanol--water and acetonitrile--water in the presence of 1-propanol. In two of the bronchiolar carcinomas, a small subpleural primary focus was demonstrated. Interleukin-1beta (IL-1beta) production of peritoneal macrophages stimulated by LPS was significantly higher in the bon narine treated group. Multiple-dose activated charcoal in management of phenytoin overdose. As determined by the degree of differences in heterotransformation for all markers, the nucleotide sequence of the xre gene diverged in the evolution process at a rate similar to that of the nucleotide sequences of the housekeeping genes. spinigerum antigens as low as 2 ng in one ml of CSF could be detected. The practise of vaccination as a standard part of fish husbandry has led during the last 20 years to the adoption of a number of basic vaccination regimes based on an understanding of the principles involved and how to maximize protection. They should be especially distinguished from metastatic adenocarcinoma.

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The oxidation of heme d1 is accurately second order with respect to oxygen and has a rate constant of 5.7 - 10(4) M-1 - s-1 at 20 degrees C. A fast spectroscopic imaging method using a blipped phase encode gradient. Frameshift mutagenesis by 2,4-dinitrophenylhydrazine in Salmonella: unexpected effect of inoculum size on mutation yield. The tumour volume on prostatectomy specimens can be evaluated by routine preparations and represents an additional element allowing better assessment of the TNM classification, as well as the predictive value of the information provided by prostatic biopsies. 3 years of clinical experience with cryosurgery in the field of general surgery. MS provera 5 mg precio farmacia guadalajara -209 directly interacts with P-glycoprotein (Pgp) and inhibits Pgp-mediated drug transport.

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The comparative sensitivity of sheep and chicken embryos to bluetongue virus and observations on viraemia in experimentally infected sheep. In histiocytic and Hodgkin lymphoma, lesions can have the same attenuation values as normal renal parenchyma on noncontrast scans but less than normal parenchyma after contrast medium administration. Effect of salt concentrations on bidisomide amaryl tabs 4mg and disopyramide was similar. Alpha 1-antichymotrypsin inhibits A beta degradation in vitro and in vivo. A review of studies on patients with endocrine syndromes, including those with an excess or lack of androgen during fetal development strongly suggest that prenatal hormones exert a limited effect on sex-dimorphic behaviors such as physical energy expenditure, childhood rehearsal of parenting, and other related behaviors.

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Early parathyroidectomy can lead to healing of the skin lesions and prevent death of sepsis. In 4 cases extensive carious destruction, and in 1 case an external granuloma led to hemisectioning. Miscellaneous records of medico-dental and pharmacological history (39). Unlike binding at other receptor sites, FLU binding increased with increasing postmortem delay to freezing. Anti-NBP antibodies specifically inhibited the binding part of this import reaction. The injury appeared to be repaired rapidly in these nestling rabbits. We successfully decannulated a 10-year-old boy, who had the tube for 18 months after stenosis dilatation. Radiotriolein revisited: a study of the 131 I-triolein absorption test using radiochemically pure triolein in man.

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Captopril (5 mg/kg) and enalaprilat (5 and 20 mg/kg) increased pain threshold. Clinical motilium syrup and instrumental functional analysis for diagnosis and treatment planning. This amino acid sequence has been demonstrated to be essential to the bioactivity of the hormone insulin. In addition to a common in vivo feature of mesenteric and retroperitoneal tumors, BALL-1 line was characterized by infiltration of the skin, massive ascites and bone marrow invasion. Behavioural changes in offspring of rats exposed to diazepam during gestation. On the biological and chemical reactivity of carbamylated glucagon.

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