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Coumadin

Coumadin is an anticoagulant (blood thinner). Coumadin reduces the formation of blood clots. Coumadin is a powerful medication used for stroke prevention. Coumadin is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions.

Other names for this medication:
Jantoven, Lycobion, Sofarin, Uniwarfin, Warfarin

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Also known as: Warfarin

Description

{name} (warfarin) is an anticoagulant (blood thinner). Warfarin reduces the formation of blood clots.

{name} is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions.

Dosage

Take Coumadin exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take warfarin in larger or smaller amounts or for longer than your doctor tells you to.

Take this medicine at the same time every day, with or without food. Never take a double dose.

Coumadin can make it easier for you to bleed. Seek emergency help if you have any bleeding that will not stop.

You will need frequent "INR" or prothrombin time tests (to measure your blood-clotting time and determine your warfarin dose). You must remain under the care of a doctor while taking Coumadin.

If you receive Coumadin in a hospital, call or visit your doctor 3 to 7 days after you leave the hospital. Your INR will need to be tested at that time. Do not miss any follow-up appointments.

Tell your doctor if you are sick with diarrhea, fever, chills, or flu symptoms, or if your body weight changes.

You may need to stop taking Coumadin 5 to 7 days before having any surgery, dental work, or a medical procedure. Call your doctor for instructions.

Wear a medical alert tag or carry an ID card stating that you take warfarin. Any medical care provider who treats you should know that you are taking this medicine.

Store at room temperature away from heat, moisture, and light.

Detailed Coumadin dosage information

Overdose

If you overdose Coumadin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Coumadin overdosage: round, small, red spots under the skin, painful menstruation, bruising, minor cuts bleeding, gums bleeding, bloody stools, heavy bleeding.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Coumadin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Coumadin if you are allergic to warfarin, or if:

you have very high blood pressure; you recently had or will have surgery on your brain, spine, or eye; you undergo a spinal tap or spinal anesthesia (epidural); or you cannot take warfarin on time every day.

You also should not take Coumadin if you are are prone to bleeding because of a medical condition, such as:

a blood cell disorder (such as low red blood cells or low platelets); ulcers or bleeding in your stomach, intestines, lungs, or urinary tract; an aneurysm or bleeding in the brain; or an infection of the lining of your heart.

Do not take Coumadin if you are pregnant, unless your doctor tells you to. Warfarin can cause birth defects, but preventing blood clots may outweigh any risks to the baby. If you are not pregnant, use effective birth control to prevent pregnancy while taking warfarin and for at least 1 month after your last dose. Tell your doctor right away if you become pregnant.

Coumadin can make you bleed more easily, especially if you have ever had:

high blood pressure or serious heart disease; kidney disease; cancer or low blood cell counts; an accident or surgery; bleeding in your stomach or intestines; a stroke; or if you are 65 or older.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

diabetes; congestive heart failure; liver disease, kidney disease (or if you are on dialysis); a hereditary clotting deficiency; or low blood platelets after receiving heparin.

It is not known whether warfarin passes into breast milk. Watch for signs of bruising or bleeding in the baby if you take Coumadin while you are breast-feeding a baby.

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Two cases of lepromatous leprosy with erythema nodosum leprosum who were on high doses of clofazimine, showed discoloration of nail plate, subungual hyperkeratosis and onycholysis. Persistent posterolateral rotatory subluxation of the elbow in cubitus varus: a case report. Relations between divalent cation binding and ATPase activity in coupling factor from chloroplast. Rosenblum, the Department of Neurosurgery at HFH has grown to include 11 full-time neurosurgeons, 2 neuro-oncologists, and 3 investigators with Ph.D. Importance of disorders of primary hemostasis in the occurrence of upper digestive hemorrhage in cirrhosis. Genetic evidence that recognition of cosQ, the signal for termination of phage lambda DNA packaging, depends on the extent of head filling. Transport of alpha-aminoisobutyric acid and 2-deoxy-D-glucose in African green monkey kidney cells was measured 8 to 100 hr following permissive simian virus 40 infection. An assessment of the application of psychomotor learning theory constructs in preclinical laboratory instruction. Otoacoustic emission and auditory efferent function testing in normal subjects and patients with sensori-neural hearing loss. A latex agglutination test was first used for the serological diagnosis of Brucellosis.

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Localization of antigens in the chromatin of normal rat liver cells, not detectable in hepatoma chromatin. These results indicate that C-cell hyperplasia is present in patients with MEN 2a and 2b and that NSE in addition to calcitonin and CEA is a useful marker for the thyroid C-cells. The effect of intravenous epinephrine on heart glycogen synthase and phosphorylase systems in control and insulin-pretreated rats was studied. Over a period of 18 months, six patients with sickle cell anaemia and neurological complications were seen. Though the mitogenic activity of lysophosphatidic acid (LPA) has been well established through classical studies, its mechanism of action was long obscure. Apparent pA2 value of naltrexone is not changed in rats following continuous exposure to morphine or naloxone. Rationale for criteria to assess respiratory therapy for patients with chronic obstructive lung disease. Polyhydroxyalkanoates (PHAs) can be produced from renewable sources and are biodegradable with similar material properties and processibility to conventional plastic materials. Development and present status of clinical bacteriology and serology.

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These organelle-poor cell profiles resemble neuroblasts in other parts of the developing CNS. Legal rights and communicable disease: AIDS, the police power, and individual liberty. In the present studies, we have tested the hypothesis that the maintenance of VT results from the concomitant contraction of the internal interosseous (expiratory) intercostals. Current knowledge about bulimia nervosa and its oral signs and preventive, interventive, and restorative strategies for dental health practitioners are presented. These 11 patients, infants less than 7 months old at onset of KD, are predominantly non-Asian. Unusual effects in liquid chromatographic separations of enantiomers on chiral stationary phases are reviewed with emphasis on polysaccharide phases. cerevisiae from a yeast genomic DNA library carried on plasmid YEp13. During the postnatal development, a recovery in the levels of the surface density with respect to controls was observed in both experimental groups. A patient with emboli in the cerebrum and in the iliac bifurcation complicating left atrial myxoma is described. If no complications occur, the transition to oral nutrition can soon be made, the basic principle of which is adherence to 6-8 small meals.

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Heretofore, their production has been hampered by ethical constraints preventing the isolation of Ag-specific activated B cells by in vivo immunization. The addition of conditioned medium from rabbit macrophages induced a rapid release of large quantities of prostaglandin E2 and an abundant secretion of collagenase, while abolishing or strongly decreasing plasminogen activator secretion. This concept has been tested in the rabbit ear model in which an injection of papain into the rabbit causes loss of proteoglycans of the auricular matrix followed by its restoration over the following eight days. This effect of injected oestrogen does not occur if the castrated animal is also submitted to thyroidectomy. The low basal metabolic rate, reduced serum thyroid hormones and elevated serum thyrotrophic hormone were consistent with primary hypothyroidism. Cellular stress associated with Al toxicity therefore causes up-regulation of a defense-related gene and a gene involved in the maintenance of cytoskeletal function.

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The study focused on the phase transformation, microstructure, functional group and thermal behavior of DPG-E with or without CO2 laser irradiation, by the analytical techniques of XRD, FTIR, DTA/TGA, and SEM. Secondary hyperalgesia to mechanical stimuli is likely due to the sensitization of central pain signalling neurons (CPSNs). Some structural properties of the histones of Caenorhabditis elegans. The recovery rate of Group A streptococci from the throat increased throughout the present study period, and the high carrier rate of Group A streptococci was maintained especially for first 8 months after the epidemic infection. Molecular cloning and characterization of a novel mRNA present in the squid giant axon.

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Feed was withdrawn 48 h prior to feeding the test ingredients and ducks were tube-fed 30 g of dextrose in 100 mL of water at 8 and 32 h after feed withdrawal. In all chub, independent of size and origin, Myxobolus cyprini occurred predominantly in the macrophage centres (MCs) of the haematopoietic organs, spleen and kidney. This competitive PCR strategy is a highly specific and sensitive way to detect small sequence differences and to monitor recombinant DNA in effluxes of biotechnological plants. A dual effect of repetitive stimulation on post-tetanic potentiation of transmitter release at the frog neuromuscular junction. It is thought that the same technique could be applied to congenital pseudarthrosis of the tibia. Morphological changes in the lympho-reticular organs (the thymus, lymph nodes, spleen) were studied and the content of the RNA was determined by the biochemical method in 92 rats during the growth of the glioblastoma multiforme (strain 101/12) in the brain. Current advice is poor--doctors give an epinephrine injector to patients, without training or advice on nut avoidance--so that further reactions are common and deaths occur. Breast reconstruction is an underused option in breast cancer management.

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Myelopoiesis following phorbol ester exposure in human long-term bone marrow cell culture. For the accumulation of both cations the critical temperature, T(c), is 13.8 degrees C the presence of millimolar external potassium. Persuasive psychological, theological, philosophical, and pragmatic arguments protest the Act as being irrational, immoral, contrary to medical ethics, and dangerous. The medical interview: differences between adult and geriatric outpatients. Recipient-type blood transfusion to the donor did not influence graft survival, nor did irradiated third-party blood or third-party erythrocytes. carbamylcholine) are compared, using the mannitol-gap technique for electrophysiological recording of synaptic events at the cercal nerve, giant fibre synapse of the sixth abdominal ganglion of the cockroach Periplaneta americana. Disorders of urinary acidification in patients with monoclonal gammapathies. The main complication was a corneal ulcer in cases 1 and 3 where the flap had crossed the central cornea. Optimization of the PCR for detection of Staphylococcus aureus nuc gene in bovine milk. Role of radiation therapy in the management of neoplasms of the central nervous system.

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The organization of tubular muscle fibers in the scorpion Leiurus quinquestriatus. Plasma alpha-protease inhibitors in Norwegian Landrace and Czech Landrace pigs. Expression of thyrotropin receptor gene in autoimmune thyroid disease and the relation to expression of HLA genes. An evaluation of minimal residual disease in childhood acute lymphoblastic leukaemia. PMA injection in the infection site resulted in severe footpad swelling accompanied by inflammatory signs such as redness, edema, induration, and imodium capsules 2mg dosage sometimes ulcer.

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Occurrence of degradation products of chicken transferrin in murine circulating blood. After 4- and 6-hour chases, the labeling of the apical tubules decreased, whereas the labeling of the plasma membranes increased, strongly suggesting that in these cells apical tubules play a major role in the transfer of glycoproteins from the Golgi to the plasma membrane. The groups were matched so that the amount of work and level of xanax pill press machine difficulty would be similar, if not identical. Thus, the two methods agreed completely in differentiating sera with antibodies to EBV antigens. Stability in culture and strong binding to melanoma tumor cells provide the basis for evaluating the potential of these human MABs. wt of about 70,000, whereas they were clearly different in antigenicity.

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