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The present study involves the observed side effects and outcome results of treating 40 male heroin addicts with the narcotic antagonist, cyclazocine, in the context of a comprehensive psychotherapeutic program. Structural information about the products formed when 7,12-dimethylbenz(alpha)anthracene (DMBA) is bound to DNA in mammalian cell cultures has been sought through studies of the photosensitivities of these products and of various model compounds. Stimulation by somatomedin-C of aminoisobutyric acid uptake in human fibroblasts: a possible test for cellular responsiveness to somatomedin. Taken together, our results show a strong correlation between M-CSFR expression and monocytic differentiation in THP-1 cells, and suggest a possible role of c-fyn tyrosine kinase in mediating these processes. Differentiated neurones were recognized with antibodies against neurofilament protein while glial cells were identified with antibodies against glial fibrillary acidic protein (GFAP). Infections of the aortic root, the ascending aorta and the aortic arch are approached with total cardio-pulmonary bypass, using cardioplegic myocardial protection and deep hypothermia with circulatory arrest if necessary. The study of T cell subsets and of natural killer cells activity did not reveal any important changes, whereas minor modifications were present in polymorphonuclear leucocyte function. The two cardiac myosin heavy chain isoforms, alpha and beta, differ functionally, alpha Myosin exhibits higher actin-activated ATPase than does beta myosin, and hearts expressing alpha myosin exhibit increased contractility relative to hearts expressing beta myosin.
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The influence of NPV on mammals was tested in animals and tissue cultures. Liver biopsy specimens were studied in 26 patients in whom liver function abnormalities developed during intravenous hyperalimentation (IVH). Reports of patient-based outcomes of implant therapy have been sparse, and none of these studies have used oral-specific health status measures. Fifteen women with metastatic breast cancer undergoing autologous bone marrow transplantation were treated with an intensive induction regimen including cyclophosphamide and mitoxantrone in a phase I-II study. Positive cerebrospinal fluid cytological findings confirm the diagnosis. Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions. Possible relation between mucopolysaccharides (hexosamine) and protein part in elastin.
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Herpes simplex virus in idiopathic facial paralysis (Bell palsy). Thin-layer chromatographic-enzymatic determination of mono-, di-, and triglycerides in glyceride mixtures. They had a complete psychiatric and neurologic examination as well. Incubation of spleen cells in vitro in the presence of ethanol, at concentrations comparable to those measured in the blood of ethanol-treated rats, significantly suppressed natural killer (NK) cell activity against MADB106 cells in a standard chromium-release assay and decreased the binding of effector to MADB106 tumor cells. Using confocal microscopy we examined the expression of transitin, vimentin and glial fibrillary acidic protein (GFAP) in cultured astrocytes, and show that transitin co-distributes with these other glial intermediate filament proteins. Like purified porcine cyclophilin, mouse sp18 exhibited peptidyl-prolyl cis-trans isomerase activity. Effects of alpha-difluoromethylornithine on the Fas expression and apoptosis in Hep-2 cells.
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Treating perforated jejunal ulcer, a complication in the Zollinger-Ellison syndrome. This study is based upon interviews with 74 individuals found to be human immunodeficiency virus (HIV)-seropositive through the screening of blood donations between January 1988 and December 1990. To test the hypothesis that arginine metabolism is altered in hypertension, aortic rings were incubated with NG-monomethyl L-arginine. Relation of lipids to the action of streptomycin on Bacillus subtilis and Escherichia coli and griseofulvin and fungizone on Aspergillus niger. Attitudes of hospital doctors in Wales to use of intravenous fluids and antibiotics in the terminally ill. Multiwell filter technique for measuring polymorphonuclear leucocyte locomotion in vitro--activation of serum in situ. Effects of orotic acid and pirazetam on cortical bioelectrical activity in rabbits.
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A watershed-based cumulative risk impact analysis: environmental vulnerability and impact criteria. However, reconstructing relationships for all the main lineages of vascular plants that diverged since the Devonian period has remained a challenge. Crystals were identified by polarizing microscopy in wet preparations of freshly aspirated synovial fluid. The case history is suggested to support the hypothesis that the cavernous sinus region is involved in cluster headache. Average patient entrance doses were 7.5, 4.9, 17.5 and 2.7 rads to the abdomen, back, and left lateral and right lateral positions, respectively. A model is presented in which the glucagon molecule exists in dilute solutions as an equilibrium population of conformers with little retention of conformers with little retention of structure, and in which the helical conformation is stablised by hydrophobic interactions either as an oligomer or as a complex with the receptor. New evidence for accelerated proliferation from Radiation Therapy Oncology Group Protocol 8313. In some dogs, ill-defined hyperechoic foci were observed within the liver during the regenerative phase.
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Domain II is highly homologous to the LDL receptor and contains four repeats with perfect conservation of all 6 consecutive cysteines. Artifacts were met when patients were unable to suspend their breath, leading to one false-positive result. The present study therefore shows that although these increases were non-tumour-specific, patients with persistent elevation of CIC and IgA levels were at much greater risk of developing recurrent disease, thereby proving the merit of these substances as markers in prognosticating the course of disease in malignant cervical neoplasia. FTIR data indicated perturbations in secondary structure upon spray-freeze drying for both excipient-free and zinc-complexed protein. Feedstuffs and foodstuffs of animal origin have to make allowance for measures of animal hygiene as well as measures which serve for protection of human health. From these results, we conclude that the capsular polysaccharide of E.
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The aim of restoring postoperative sinus rhythm after mitral valve repair should lead to surgery being conducted on patients who have sinus rhythm or recent-onset atrial fibrillation. Angiopathy is a significant complication of diabetes that often results in tremendous losses for the client: vision, mobility, a sense of well-being, occupational choice, independence, and financial security. The analysis of alleles segregation of the heterozygous trees on the whole confirms monogenic inheritance of the discovered variants. Cardiac damage following radiation treatment of primary breast cancer: assessing the risk, exploring the cause. The study evaluated the tensile bond strength between human enamel and seven compomer restorative systems under different bonding conditions.
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Far fewer effects of the treatments were detected on the measures of appetitive behavior. Motion of the left ventricular cavity center during the cardiac cycle was compared using transthoracic and intracardiac echocardiography. Adherens junctions inhibit asymmetric division in the Drosophila epithelium. Creating a center of excellence: education and service collaborate. The amino-acid sequence of the double-headed proteinase inhibitor from badger (Meles meles) submandibular glands. These findings are interpreted in terms of the need for CMHCs to specialize either on the aged or on other client populations. Preparation and progestational activity of 6-cyano-16-methylene-17 -hydroxy-4,6-pregnadiene-3,20-dione 17-acetate and related compounds. At a time when financial constraints are forcing us to make choices, there is an urgent need to assess the effectiveness and the cost of the various elements of our prenatal monitoring. Due to lack of more suitable materials we elaborated ten years ago our own technique which we use nowadays for treatment but in particular for prevention.
MT1-MMP was found in sclera, cornea, lens, choroid, retinal pigment epithelium (RPE) and retina. Two years after the injury, all her dietary intake is oral but she will not yet ingest solids. The concentration of MT did not significantly correlate with the TBA value in either the menadione or the CCl4 group. Role of cortisol on the glycogenolytic effect of glucagon and on the glycogenic response to insulin in fetal hepatocyte culture. Whole-body, chamber exposure to concentrated SS, generated from smouldering cigarettes, caused a dose-dependent reduction in rat pulmonary, hepatic, renal, cardiac and bladder muscle GSH but only affected pulmonary GSH in the guinea pig.
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Microsatellite mutations were studied in a set of 175 mutation accumulation lines, all of them independently derived from a completely homozygous population of Drosophila melanogaster and maintained under strong inbreeding during 80 generations. LSN lesions in hypophysectomized rats have no effect on the ovary and uterus weights as compared to hypophysectomized ones, but decrease the size of mature ovarian follicles against a background of hypophysectomy or LSN lesions. 1) After portal administration of palmitic acid-1-14C, alpha, beta-mono-unsaturated fatty acid (C18:1) was synthesized as a result of chain elongation by addition of endogenous C2 compound 20 min. Characteristics of the adrenal hypertrophy produced by indium triacetate. In addition, high dose chemotherapy followed by autologous stem cell transplantation is limited by tumor cell contamination in the stem cell harvest. No difference between the Hafnia A and D systems could be demonstrated in the values of arterial carbon dioxide tension measured with the same fresh gas flow, despite gas flows in opposite directions. The isolates were resistant in vitro to all tested antibacterial drugs except vancomycin.
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Comparisons of GLC and mass spectral data to a compound isolated from the body fluids of glutethimide overdose victims conclusively identified a new 3-methoxy-4-hydroxyphenyl metabolite of glutethimide in humans. Subglottic biopsy, first interpreted as paraganglioma, was finally diagnosed as medullary carcinoma of the thyroid. Radiologic diagnosis of persistant common atrio-ventricular canal. Only one trial demonstrated that a CSF led to a reduction in the number of hospital days. - Methods for morpho-functional investigation, especially Isotopoangiocardiopneumography using gamma-camera and Tc99mO4. As excreted in the urine, the protein appeared to be a half-molecule of IgA, with a partial deletion in the heavy chain, probably involving part or all of the C-terminal domain. The specificity and quantitation of the rescue of RNA sequences by mammalian type C viruses has been investigated.
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A higher proportion of symmetry was observed for the right and left tooth pairs and the lingual surfaces showed a greater percentage of bilateral distribution. Cells were enzymatically released from the periosteum of the proximal tibia obtained from adult human donors and expanded in monolayer. Preliminary information on a new viral hemorrhagic fever in Africa. They presented a smooth rim-like nuclear immunofluorescence staining pattern. The resulting two-dimensional lipid distribution is nonrandom, consisting of clusters of phospholipids bound to cytochrome c and patches of steroid spin-label molecules. Brugia pahangi infections of jirds (Meriones unguiculatus) produce a granulomatous inflammatory response within the lymphatic vessels. Several regulatory sequences, including five activator protein-1 (AP-1), five activator protein-2 (AP-2), five glucocorticoid-response elements and multiple ets/polyoma enhancer-binding 3 elements, were identified. It is postulated that the symptoms might have occurred as a result of an imbalance in brain norepinephrine, dopamine, and acetylcholine levels induced by the indeloxazine. For pulsed heating, experimental and numerical modelling results for carbon fibre-reinforced plastic are used to show how the resolution of subsurface features depends on their size and depth and on the anisotropy in thermal materials properties common in such composites. Using a one-step silver staining technique, AgNORs were counted in surgical specimens from 54 patients with squamous cell carcinomas.