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Swainsonine is a useful tool to monitor the intracellular traffic of N-linked glycoproteins as a function of the state of enterocytic differentiation of HT-29 cells. Involucrin is synthesized after keratinocytes have left the basal layer and begun to enlarge, but some time before the onset of envelope cross-linking, which occurs only in the outermost cell layers. Recognizing that the data from these surveys are becoming dated, a multidisciplinary team comprising members from various NIOSH research divisions was established to develop a hazard surveillance strategy for the Institute, including options for a national hazard surveillance survey and database. Evolution of medical pedagogical concepts concerning deaf mutism. Half a year postoperatively a gingival retraction and sequestration of osseous tissue occurred. The Increasing concentration (10-8-10-4 M) of NO donors, Sodium nitroprusside, (SNP) and molsidomine (SIN-1) and a type V phosphodiesterase inhibitor, Zaprinast were added to the organ chambers and a dose response curve was constructed from each experiment. The authors consider that in most cases with traumatic insufficiency of the mitral valve after closed commissurotomy it is possible to perform valve-preserving operations, craniocerebral hypothermia being a reliable method of their maintenance.
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Stable isotope studies have considerable potential to help understand the biochemistry and pathophysiology of inborn errors of metabolism but this has not yet been fully realised. Compared to mean value setting, facebow registration of condylar angle and relations yields no profitable improvement of occlusal accuracy. Root dentin morphology after different modes of citric acid and tetracycline hydrochloride conditioning. Genetic technology of substances important from the therapeutic and diagnostic aspects. Chemical degradation of one particular epitope recognized by monoclonal antibody PP1/117, and designated ep117, occurred after treatment with NaOH, periodate or Proteinase K, suggesting that an O-linked glycoprotein may be involved. Five and 15 mM HCO-3 increased, but 25 mM HCO-3 decreased, deposit of fluoride in enamel. The efficacy of TPA in elevating ODC activity at postnatal ages 1-220 days-old was independent of both soluble-and particulate-associated TPA receptor concentration. We report the case of a 67-year-old woman in whom onset and regression of acute hepatitis were closely related to the time of administration and withdrawal of the smooth muscle relaxant alverine.
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A severe state of even a single symptom may suffice to cause impairment of QOL, although a poor QOL need not necessarily imply that a patient suffers from all the symptoms. Later on arthralgia of the left shoulder and diffuse swelling of both hands and feet appeared. The diabetic hearing impairment was characterized by high frequency sensorineural hearing loss. Data were gathered from 259 students, fieldwork supervisors, and faculty who rated the form on a number of variables. The incidence of fluorescent Y corpuscles in solid tumors (preliminary report). Relative hypermetabolism of the lenticular nuclei (1) occurred irrespective of whether the spasms were cryptogenic or symptomatic, (2) was associated with focal cortical hypometabolism in 22 and focal cortical hypermetabolism in 5 of the 44 infants, and (3) was not characterized by any specific electroencephalographic abnormality during PET. Methylmethacrylate is widely used by orthopaedic and neurosurgeons for bone reconstruction. Normal daily fluctuations in plasma 45Ca, lost after thyroparathyroidectomy, were restored by feeding rats a high-calcium diet.
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It is known that Dalmatia and then Montenegro are the most infected areas in Yugoslavia. A gas jointer developed dermatitis from epoxy resin of Bisphenol A type. Fibrinogen association with platelets from rats with spontaneous or streptozotocin-induced diabetes was significantly greater 10 s or 1 min after addition of ADP (10 microM) than with platelets from their corresponding control rats. Since the 1980s, clinical trial evidence has supported aspirin use in the secondary prevention of cardiovascular disease (CVD). 17 other published cases of hypoplasia of the right ventricle with atrial septal defect are reviewed. The enzyme requires reduced pyridine nucleotide and dialysis prior to assay for optimal activity. Use of X-ray method for examination of thoracic spine in expert practical work makes it possible to detect lesions and mechanism of their formation. At these levels even penicillin G eliminates many Gram-negative urinary pathogens. They evidence the benefits of the wear of soft hydrogel lenses but the limits of their uses too. The clinical value of the pollico-mental reflex in neuropathology.
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We report on 12 children with neuronal ceroid lipofuscinosis (NCL) diagnosed between 1974-1995 in the West of Scotland. Thus ingestion of ethanol should reduce the risk of liver damage following acetaminophen overdosage. Because LDL increases the supply of arachidonic acid for prostaglandin synthesis, we postulate that greater amounts of PGH2/TxA2 are synthesized via calcium activation of phospholipase A2 when acetylcholine is administered to CSD animals. Migration of plastic additives from soft polyvinyl chloride bags into normal saline and glucose infusions. Hemodynamic parameters were compared in 28 patients with ischemic heart disease subject to cardiopulmonary bypass surgery with non-pulsatile (group 1) and pulsatile flow (group 2). Syphilitic uveitis in human immunodeficiency virus-infected and noninfected patients. In the liver diffusely distributed nodules of regenerative hyperplasia were noted. I reviewed factors contributing to diagnostic delay in 12 children who had symptoms of meningitis for more than three days before diagnosis. Activity profile of placental superoxide-superoxide dismutase system in pregnant mice and its possible relation with placental steroidogenesis.
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The epidermal changes associated with psoriasis may be due to the infiltration of inflammatory T lymphocytes and the release of cytokines in response to antigenic stimulation. Studies to date indicate that adenovirus type 11 is the etiologic agent in some but not all pediatric cases of acute hemorrhagic cystitis. Ten minutes before sacrifice they were injected with a single intravenous dose of ferritin. Since electron linear accelerators with energies up to 20 MeV were introduced to radiotherapy it has become easier to irradiate large portals than was previously possible with 60Co unites or betatrons. In the globular stage expression was confined to the basal part of the embryo, suggesting that the promoter is sensitive to regulatory functions active in the primary establishment of polarity in the radially symmetric globular embryo. The peptides were administered alone or together with glucose (40 mg/kg . Pancreatic tumours display different vascularization patterns in the echo-enhanced power-Doppler sonography. Identification and characterization of a novel gene (neurorep 1) expressed in nerve cells and up-regulated after axotomy. Evaluation of a bivalent (CVD 103-HgR/CVD 111) live oral cholera vaccine in adult volunteers from the United States and Peru.
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It is hypothesized that adolescent development involves a redistribution of cerebral functions from lower subcortical structures to higher regions of the prefrontal cortex to provide greater self-control over emotional behavior. For surfaces defined by motion, the lifetimes of the individual points in the patterns were varied, and comparisons were made between the perception of surfaces defined by points and that of more ecologically valid textured surfaces. PRA, aldosterone and norepinephrine levels remain unchanged during dopamine infusion. Future studies employing sequential IVUS examinations are needed in order to determine whether these morphologic differences relate to a delay in initiation of plaques, slower progression of plaques, or other sex-specific modulators of plaque composition. The incidence of nocturnal hypoxemia without upper airway obstruction or daytime hypoxemia is not known but may be small. In addition, both the basal and the fluoride-stimulated adenylate cyclase activities decrease as the embryo age increases, whereas the enzyme sensitivity to epinephrine increases with increasing age of the embryo.
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Analysis of the cause-specific mortality revealed a significantly raised mortality from gastrointestinal diseases, including a significant excessive mortality in the subgroups of benign peptic ulcer and cirrhosis of the liver. Rats were prepared with indwelling IV cannulae, made tolerant to and physically dependent on morphine, then trained to lever press for morphine self-injections on a fixed ratio (FR) schedule of reinforcement. Fifteen isolates of Bacillus species were recovered during a 19-day period after the introduction of an automated radiometric blood culture system. Forty human insulin-producing tumors were investigated with histochemical, immunohistological and ultrastructural methods and extracted for insulin and proinsulin. Following the sociologist Georg Simmel the thesis is presented that quarrel does not destruct social order but constructs. The action of sinusoidal modulated currents with different parameters in experimental chronic infectious salpingitis.
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Single gene for the large subunit of ribulosebisphosphate carboxylase in maize yields two differentially regulated mRNAs. After a brief description of the two most frequently used experimental models of perfused hearts, namely the Langendorff preparation and the working heart preparation, some of the various methods used to induce hypoxia or ischaemia are described, as well as some of the possible techniques allowing to assess metabolic alterations occurring in these pathological situations. Effects of T mitogens on in vivo antibody production to a T-dependent antigen in lines of mice genetically selected for high or low in vitro responsiveness to PHA. Methylchymotrypsin retains unaltered its ability to bind specific substrates, but is essentially inactive. An early and important step in the generation of neural diversity is the specification of individual neuroblasts according to their position. Duodenal somatostatinoma and erythrocytosis in a patient with von Hippel-Lindau disease type 2A.
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At low concentrations and in the absence of exogenous ADP, non ionic as well as ionic detergents provoked a threefold (or fourfold) increase of the respiratory intensities of mitochondria. Care in the MSSU is provided by a rotating group of hospitalists. After all types of transfusion plasma glucocorticoid levels remained relatively constant for one hour and then doubled and then doubled in the second and third hour. Treatment was successful, and the relatively long parasite clearance time and fever clearance time were probably characteristic of P. The surround responses are antagonized by the responsive center and suppressed by the inhibitory surround, but are seen because of their slower dynamics. Endovascular occlusion of the carotid or vertebral artery with temporary proximal flow arrest and microcoils: clinical results. Aging is associated with insulin resistance but the exact molecular mechanism is still unknown. On the basis of this study and previously reported histopathologic studies of tissue compatibility, it appears that ProcoSol is the material of choice as an endodontic sealer/cement. Aneurysmal bone cyst of the axis treated by laminoplasty with autogenous iliac bone.
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Absence of a specific enzyme from liver and brain of Niemann-Pick disease, type C. Based on personal knowledge and involvement the author describes the ideas, the problems, and the people who combined to advance this aspect of optometry. The role of nasal chemical senses in garter snake response to airborne odor cues from prey. Agarose column chromatography has been used to separate plasma lipoproteins into very-low-density lipoproteins (VLDL), low-density lipoproteins (LDL) and high-density lipoproteins (HDL). These cells were non-ciliated cells and comprised a majority of the epithelial cells especially in the ventral/cartilaginous portion of the airway. Chordoma is a rare and slow-growing tumor, with local aggressiveness and preferential localization in the vertebral column. The total amount in malignant bone tumours was 2.4 times higher compared to benign bone tumours. After prostatectomy, hypofibrinogenemia and bleeding were reported earlier. In particular, it is taken into account that the phospholipid membrane is composed of two layers which are in contact but unconnected. These studies indicate that clinically MER may be a suitable alternative to BCG for contact suppression of tumour growth or incorporation into tumour cell:adjuvant vaccines for active immunotherapy.
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Degeneration, destruction, oedema, haemorrhage and thrombosis were observed in tissues from patients who died due to heart, lung, renal and hepatic failure. This difference was most marked with the enzyme from rat liver, especially with 3beta-hydroxyandrostan-17-ones and 3beta-hydroxypregnan-20-ones as substrates. To test if metoclopramide could act through a serotoninergic pathway we have studied the effect of metergoline on the aldosterone response to metoclopramide in 8 normal subjects. A statistically significant difference was also found between lateral condensation of gutta-percha and vertical condensation of warm gutta-percha using Kerr sealer cement. influenzae type B was recovered from seven of the febrile children with facial cellulitis, and one with extremity involvement.