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Imdur (Isosorbide)
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Imdur

Imdur is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). This medication belongs to a class of drugs known as nitrates. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.

Other names for this medication:
Aspitrate, Dilatrate, Ecosmin, Ismorin, Ismotic, Isoditrate, Isoloprin, Isordil, Isosorbide, Monit, Monoket, Monosprin, Nitren, Nitrofix, Nitroprin, Solosprin, Vasoprin

Similar Products:
Allegra, Astelin, Benemid, Wellbutrin, Imuran, Revia

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Also known as: Isosorbide

Description

Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). It does not work fast enough to relieve the pain of an angina attack that has already started.

Isosorbide mononitrate belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.

This medicine is available only with your doctor's prescription.

Dosage

Take Generic Imdur tablets orally with or without food. Do not crush or chew it. Take Generic Imdur at the same time with water. If you want to achieve most effective results do not stop taking Generic Imdur suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of isosorbide mononitrate can be fatal.

Overdose symptoms may include a severe throbbing headache, fever, confusion, severe dizziness, fast or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cold or clammy skin, fainting, and seizure (convulsions).

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Imdur are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of isosorbide mononitrate in the pediatric population. Safety and efficacy have not been established.

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The relation to the brain stem as a cause of this fact is discussed. As there are comparatively high dmf-s values (34.1 in the average) at the early age of 3-4 years, it seems to be most important to stress the value of a balanced lactovegetabile nutrition, a sufficient oral hygiene and the indispensable caries prophylaxis by fluorides. With its mesial rest and special retentive arm design, it gives essentially the same kind of tooth release that the RPI clasp provides. Ketogenesis from lactate in rat liver during the perinatal period. The internal intercostals were usually inactive in our preparation and therefore their length excursions passively followed those of the external intercostals. Comparative and functional morphology of musculus canalis ani in tetrapod mammals and primates. Although thigh girth changes correlated well with body mass, they did not correlate with knee extensor strength. Teratogenic effects of sinusoidal extremely low frequency electromagnetic fields on morphology of 24 hr chick embryos.

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In practice, however, competitive risk rating costs more than noncompetitive, universal systems of health insurance, and it erodes the basic function of insurance to spread infrequent large losses over a wide base. Pneumoperitoneum following gastroscopy without demonstrable perforation at laparotomy. Approaches that allow the assessment of potentially antigen-reactive T cell populations ex vivo are thus an important advance in the global appraisal of anti-tumor T cell immune responses. It is suggested that decorrelation of MS activity by gamma influence may improve the fidelity of the information transmitted by the Ia MS ensemble by filtering distortion harmonics, as well as damping tremor oscillations in the stretch reflex loop. A randomized trial of sodium intake and blood pressure in newborn infants. Santiago for performing some of the studies reported in this review. In parallel, liposomes labeled with a fluorescent phospholipid analog were injected into tumor-bearing rats. Severe renal damage limits the conversion of vitamin D to its active form and contributes to vitamin D resistance. A second major finding was the remarkable allele diversity in malT within a population derived from a single clone, with at least 11 different alleles co-existing in a population.

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To compare two methods concerning the clinical evaluation of infarct size--one using a QRS score, the other based on peak Ck values--applied to the same population. Pip2p and Oaf1p form an example of a heterodimere of yeast Zn2Cys6 zinc-finger proteins binding to DNA. The results showed that progressive activation of a screw plate caused an initial increase in labial archwire force, which was subsequently followed by a minor reduction, and which stabilised after 90 seconds. Possibilities for using the method of integral rheography in the polyclinic. Effect of refeeding following short-term deprivation of feed or water, or both, on selected physiological parameters for broiler chickens. Laboratory studies have a low sensitivity and specificity in the elderly patient and should be ordered selectively. The influence of glutaraldehyde concentration, cross-linking reaction time, drug-loading patterns, and type of release media on the in vitro release characteristics of amoxicillin from the microspheres was investigated.

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Is allogeneic bone marrow transplantation the best treatment for young adult patients with acute myeloid leukemia in first complete remission. Successfully prepared AdCMV.hVEGF165 could express biologically active VEGF in infected VSMC, and stimulate proliferation of HUVEC. The structure of a new antitumor antibiotic SF2575, has been determined by spectroscopic analyses of the antibiotic and its alkaline degradation products. The values of the lysozyme activity in the spleen and lungs of the animals treated with neocid in combination with sarcolysine were higher for 5 days, and in all organs examined were higher by the 10the day as compared to the animals treated with neocid alone. Twenty patients (11 females, 9 males) with chronic HCV hepatitis and without detectable cryoglobulins were submitted to neurological and electrophysiological studies to detect a possible peripheral neurological involvement. Observations on the early development of the dorsal root ganglia and ventral root in quail embryos. A technique that provides a craniocaudal axial view of the sacroiliac joint is described.

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From a diagnostic point of view an intraoperative ultrasound scan was useful, revealing the presence of a roundish neoformation, irregularly hypogenic, with a different appearance from anything observed by the authors in the other intraoperative ultrasound examinations of renal masses. Effect of low fibrinogen concentrations on the rheology of human blood in vitro. In adults, migrating motor complexes (MMCs) appear to be partially under hormonal modulation by motilin and pancreatic polypeptide. Mitochondrial DNAs from yeast, Neurospora, rat and calf do not contain internally methylated cytosine in -CCGG- sequences. Method for the quantitative examination of bone marrow of white rats. The common use of automated metabolic screening has led to the early discovery of many patients with hyperparathyroidism and an increase in the number of operations performed upon the parathyroid glands.

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Specially selected psychologic tests relevant to shooting have been followed up paralelly. Pelvic floor muscle strength, defined as the weight in grams of the heaviest cone that could be retained in the vagina, was recorded before and after the 12-week training period. Intensive care of the patient with cancer after reconstructive surgery. Their structural characteristics are described and related to a three-dimensional structure of a chloroplast-type ferredoxin. The experiments indicated that under the optimum determining conditions a linear relationship was obtained between the fluorescence intensity and chlortetracycline concentration in the range of 2.0 x 10(-8)-1.0 x 10(-5) M. When small doses of herpes simplex virus (HSV) were given to rabbits a significant degree of protection was afforded against later infection with herpes simiae (B virus). SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport. These substances resemble cholesteramine in activity but are distinguished by solubility, low toxicity, and a mechanism of action which is more physiological. We performed 15 lobectomies, 10 wedge resections, 16 decortications, and in one patient simple drainage of a voluminous pleuropulmonary and hepatic purulent hydatic collection. Radiohumeral arthrodesis for salvage of failed total elbow arthroplasty.

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A method for reducing nonspecific reactions in the typing of human skeletal material. Isoenzyme spectrum of lactate and malate dehydrogenases in the gingival fluid in periodontitis of various degrees of severity. Stoichiometry of carbon monoxide binding by cytochrome c oxidase. Cerebral perfusion deficits were detected in methamphetamine abusers even after a long abstinence period, suggesting that vascular changes were irreversible to some degree. Pediatric core needle biopsy: strengths and limitations in evaluation of masses. Cell-mediated immune reactions against carcinogen-induced rat tumours were demonstrated by the in vitro microcytotoxicity test. Additionally, students indicated that the collaboration of medicine and pharmacy provided an educational model that should be duplicated for future courses. This review attempts to summarize the information given by 32 twin chimeras, 32 dispermic chimeras and 11 chimeras of unestablished type. Although fibroblast cultures demonstrated enhanced radiosensitivity, there was no undue toxicity associated with treatment, which included methotrexate, cisplatinum and Adriamycin. It is concluded from these studies that the large external transformation sensitive (LETS) protein detected by other workers is the same molecule as SF210.

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These results suggest that DA plays an essential role in the hyperpyrexia induced by the combination of TCP and LiCl in rats, but the involvement of 5-HT is inconclusive. The mechanical data were analyzed by calculating a motility index. Extinction of a target for a gap interval elicited very short latency movements (122 ms), termed express saccades. Epinephrine (1muM) infusion increased both cyclic AMP content and phosphorylase, but did not alter cyclic GMP content or glycogen synthase activity. They can display relatively to extremely small geographical size depending on the diseases considered. Patients who suffered from depression in which retardation and delusions were features and who received real ECT had a significantly improved outcome at the end of four weeks of treatment (as measured by improvement in the HRSD) in comparison with those who received simulated ECT. We stress the need for frequent assessment of vision before considering potentially hazardous surgical intervention. Twenty-five per cent developed strictures of the small or large intestine.

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Thus, we deduce that intracystic bodies resulting from meiotic nuclear division are haploid and, after excystation, they are haploid trophozoites. The lowest concentration of particles tested clearly decreased the signal intensity. Neither group had any significant complications, indicating the safety of percutaneous catheterization of the graft site. Comparisons were made to images obtained with the patient in the lateral decubitus position. epidermidis is a stable characteristic retained after animal passage and may be important in the pathogenesis of these infections. The width of cavities prepared with two experimental rocaltrol drug diamond points and the smallest commercial diamond point were compared and significant differences found. Although successful in animal models of sepsis, inhibiting host inflammatory response in human sepsis has failed to improve survival or otherwise show efficacy. Among women, in each year of follow-up, the unemployed had a much higher suicide risk than the employed. The test is simply used and recommended for mass prophylactic population screening. Participation of cyclic AMP in the electrical activity of the pacemaker.

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Vestibulo-ocular reflex and visual vestibulo-ocular reflex during sinusoidal rotation in children. Report of two cases, personal experience and review of the literature. The MPD and ADD groups did not differ significantly from the comparison group in this respect. This study was undertaken to determine ethnicity/race-specific (white, black, and Hispanic) population-adjusted rates of US office-based physician visits in which a protonix ec tablet diagnosis of a depressive disorder was recorded or in which a diagnosis of a depressive disorder was recorded and antidepressant pharmacotherapy was prescribed. Insulin-induced glucose utilization influences triglyceride metabolism. Varicella-zoster virus-induced transformation of mammalian cells in vitro.

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Letter: Sexual abuse and herpetic genital infection in children. srRNA evolution and phylogenetic relationships of the genus Naegleria (Protista: Rhizopoda). No influence of conversions affecting allotype expression on the IgG subclass restriction of specific antibodies. While chitosan ascorbate underwent degradation in vitro, especially in the presence of atmospheric oxygen and at pH 6.0, the protection from oxygen offered by the surgical cements and the physiological pH value permitted chitosan ascorbate to play an important biological role in vivo, where it kept a honeycomb structure, as indicated by SEM on biopsies taken on 10 patients. The dissection was limited to the intima and internal elastic lamina. Smoothest surfaces are generally obtained with the use of a finisher. Antiserum raised against a pancreatic duct mucin was absorbed with type AB red blood cells and used in the indirect immuno-glucose oxidase procedure to examine tissue specificity.

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Juvenile males fed the HF diet weighed more than chow-fed controls before and throughout the hibernation season and had significantly greater lipid masses at terminal arousal. Brain migration disorder and T-cell activation deficiency associated with abnormal signaling through TCR/CD3 complex and hyperactivity of Fyn tyrosine kinase. The potential merits of the formulation were demonstrated by its profoundly improved lactone stability in vivo, favorable pharmacokinetic and biodistribution characteristics in rats, and enhanced desyrel reviews preclinical efficacy in tumor-bearing athymic mice. On the basis of theoretical framework for extended ligand binding to one-dimensional lattices such as DNA we have set up systems of equations which relate the ligand-to-DNA ratio to the observed gel migration distance of the complex. Left and right ventricular activation and pace mapping proved inadequate for radiofrequency application in a patient with idiopathic ventricular outflow tract tachycardia. The test of 70 degrees passive head-up tilt and other hemodynamic tests were performed upon the subjects, and the results were pooled by ages.

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Persistent infection of mice by lactate dehydrogenase-elevating virus: transient virus replication in macrophages of the spleen. The infant immunization coverage for triple antigen (DPT) from 1968 and trivalent oral polio vaccine (TOPV) from 1972 to 1985 for Peninsular Malaysia are presented. Papaverine, cyclic AMP and the dependence of the rat aorta on extracellular calcium. A 43-year-old woman presented with acute abdominal pain and signs of ileus. Identical hypervariable regions in light chains of differing V kappa subgroups. These changes were examined in the light of concurrent changes in other serological variables, overall disease activity, neuropsychiatric disease and neuropsychological tests. The comparison of individuals with tension-type headache oxytetracycline and alcohol and headache-free controls on frontal EMG levels: a meta-analysis. Eight dams in each group were given AKW or TPW (control) from day 0 of gestation to day 14 of lactation. Contemporary views of pharmacologic treatment for congestive heart failure. These problems can be further reduced by the use of denaturing gradient gel electrophoresis to identify those alleles in need of sequencing.

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None of numerous variations in culture media, including alterations of serum concentration and source, improved the rate of cell multiplication or in vitro longevity. Clinical trial of the preparation Verbascan in treating gastrointestinal and biliary diseases. To facilitate the study of the effects of carbon catabolite repression and mutations on 5-aminolevulinate dehydratase (EC 4.2.1.24) from Saccharomyces cerevisiae, a sensitive in situ assay was developed, using cells permeabilized by five cycles of freezing and thawing. At incubation medium glucose concentrations of 11.1 mmol/l or higher, no effect of gender was observed, although the glucose oxidation rate of islets from male 26-mo-old rats was greater than that of islets from gender-matched 6-mo-old rats. The T2 values were elevated only in two out of six cases during the episode.

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Certain pharmaceutically important compounds such as pyrocatechol derivatives and hydroquinone appear to reduce blue tetrazolium by the anion free radical mechanism proposed previously. Regularly we examined fetal ultrasonographic growth, doppler measurements of fetal and max im geodon dose maternal vessels and CTG, as well as indicated amniocentesis, placentesis and cordocentesis. This rare reaction simulating sepsis in patients treated with cotrimoxazole is of clinical importance. A 31141 bp continuous nucleotide sequence in the region from trnl to pNEXT52 in the Bacillus subtilis 168 genome was determined. Absorption of complete and incomplete antibodies by precipitation and passive hemagglutination. Immune and hematopoietic parameters in HIV-1-infected chimpanzees during clinical progression toward AIDS. c) Another consequence of the shift can be the different involvement of the conducting pathways which can lead to a change in the dynamics of the atrial invasion by the excitement. An additional example of perinatal Torulopsis infection which is associated with maternal sickle cell anemia is reported.

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Of these 100 sonograms of renal and perinephric abnormalities 92 were correct by anatomic diagnosis. Photocolorimetric determination of arbutine in the leaves of Uva Ursi. The purified empty capsids had the same immunogenicity as poliovirus virions. We used a lactose-substituted polystyrene, poly-N-p-vinylbenzyl-D-lactonamide (PVLA), as a substratum for adult rat hepatocytes in primary culture. However, this statistical picture of a healthier nation conceals considerable differences in health status between social classes, so that a different approach is required by public health professionals. Human genetics: past, present, and future, with special reference to major trends in Japan. Four-week-old broiler chickens were given either semi-synthetic starch-based diets containing maize, wheat bran, meat-and-bone meal or fish meal as the sole sources of protein or each of these diets in combination with the basal diet (50:50 on a dry matter basis). Sixteen patients with unusual heteromorphisms involving alterations of the length and/or position of centromeric heterochromatin are described. Purification and properties of the adenosine triphosphatase released from the liver mitochondrial membrane by chloroform.

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