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Levothroid (Levothyroxine)
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Levothroid

Levothroid is used to treat hypothyroidism (low thyroid hormone). Levothroid is given when your thyroid does not produce enough of this hormone on its own. Levothroid is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer.

Other names for this medication:
Eltroxin, Levothyroxine, Levoxyl, Roxin, Synox, Synthroid, Thyronorm, Thyrosec, Thyrowin, Thyrox, Unithroid

Similar Products:
Glucophage, Xeloda, Ovral, Adipex, Starlix, Nizoral

Also known as: Levothyroxine

Description

Levothyroxine injection is used to treat myxedema coma (severe hypothyroidism), a condition where the thyroid gland does not produce enough thyroid hormone. The powder form of levothyroxine injection can be used as a substitute for the oral dose when a rapid effect is needed and when the oral route is not allowed.

This medicine is to be given only by or under the supervision of your doctor.

This product is available in the following dosage forms:

  • Powder for Solution

Dosage

This section provides information on the proper use of a number of products that contain levothyroxine. It may not be specific to Levothroid. Please read with care.

This medicine will need to be taken for the rest of your life or your child's life. Do not stop taking this medicine or change your dose without first checking with your doctor. It may take several weeks before you start to notice that your symptoms are better.

It is best to take this medicine on an empty stomach. Take it with a full glass of water at least 30 minutes to 1 hour before eating breakfast.

Swallow the capsule whole. Do not cut or crush it. Also, if you are taking multiple strengths of this medicine, remove the capsules from the blisters in advance to help you identify the strength of each capsule.

For infants and children who cannot swallow the tablet form, the tablet can be crushed and mixed with a small amount of water (5 to 10 milliliters [mL] or 1 to 2 teaspoonfuls). You may use a spoon or dropper to give the mixture. Use the mixture right away and do not store it to use later.

If you are using the oral liquid:

This medicine should come with patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions. This medicine may be mixed with water or be given directly into the mouth. If mixed with water, squeeze the contents of 1 single unit-dose ampule into a glass or cup containing water. Stir and drink it immediately. Add some water to the glass or cup and drink the water. This will help get all of the medicine out of the glass or cup. Do not mix this medicine with any other liquid except water. Do not store the mixture for later use. If taken without water, squeeze the medicine directly into the mouth or into a spoon and swallow it immediately.

This medicine should be taken at least 4 hours before or 4 hours after these medicines: antacids (Maalox®, Mylanta®, Tums®), calcium supplements, stomach medicines (including lansoprazole, omeprazole, pantoprazole, Aciphex®, Dexilant®, Nexium®, Prevacid®, Prilosec®), cholestyramine (Prevalite®, Questran®), colesevelam (Welchol®), colestipol (Colestid®), iron supplements, Kayexalate®, orlistat (Alli®, Xenical®), simethicone (Gas-X®, Mylicon®), and sucralfate (Carafate®).

Cotton seed meal, dietary fiber, soybean flour (infant formula), or walnuts may affect the absorption of this medicine from your body. You may have to take this medicine at a different time of day from when you eat these foods. Talk with your doctor more about this if you have concerns.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (capsules): For hypothyroidism: Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 1.7 microgram (mcg) per kilogram (kg) of body weight per day but may be less in older adults. Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day. Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day. Children younger than 6 years of age—Use is not recommended as your child might not be able to swallow the capsules. For thyroid cancer: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually more than 2 microgram (mcg) per kilogram (kg) of body weight per day. Children—Use and dose must be determined by your doctor. For oral dosage form (solution): For hypothyroidism: Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 1.7 microgram (mcg) per kilogram (kg) of body weight per day. Your doctor may adjust your dose as needed. Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day. Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day. Children 1 to 5 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 to 6 mcg per kg of body weight per day. Children 6 to 12 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 6 to 8 mcg per kg of body weight per day. Children 3 to 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 8 to 10 mcg per kg of body weight per day. Children 0 to 3 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 15 mcg per kg of body weight per day. For thyroid cancer: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually more than 2 microgram (mcg) per kilogram (kg) of body weight per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablet): For hypothyroidism: Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 1.6 microgram (mcg) per kilogram (kg) of body weight per day but may be less in older adults. Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day. Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day. Children 1 to 5 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 to 6 mcg per kg of body weight per day. Children 6 to 12 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 6 to 8 mcg per kg of body weight per day. Children 3 to 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 8 to 10 mcg per kg of body weight per day. Children 0 to 3 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 15 mcg per kg of body weight per day.

Overdose

If you overdose Generic Levothroid and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Use the oral liquid within 15 days after opening the pouch. Keep the ampules in the pouch until you are ready to use them.

Side effects

The most common side effects associated with Levothroid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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The membrane serves as an interface across which liquid-liquid extraction takes place. Staphylococcus intermedius-specific IgA cross reacted with Staphylococcus aureus but not with Gram negative bacteria. The detection and characterization of soluble immune complexes is complicated by the broad spectrum of complexes occurring in human pathology. In the present study, we analyzed whether impaired myelination of retinal ganglion cell axons is detectable in adult MAG mutants. The first R406W brain showed many NFT in affected regions with only a few diffuse amyloid plaques. Results for several liquids and solutions such as water, methanol, various saline solutions, and solutions of DNA and DNA sodium salt in water are described.

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At lower shear rates, increased red cell aggregation, primarily mediated by elevated fibrinogen concentration, accounted for the higher blood viscosity in the hypertensive subjects. Cyclooxygenase (COX) is an intracellular enzyme that converts arachidonic acid into prostaglandin (PG)G2 and PGH2. Taken together, these results suggest that biologic activities of HIV-1 Tat in human monocytes may, at least in part, be elicited by activation of VEGFR-1/Flt-1. Further improvements in the survival of patients with cholangiocarcinoma will come with the early diagnosis of these lesions. Prevalence of susceptibility to quinolones and other antibiotics in microorganisms isolated from community bacteriuria in Madrid in 1995. Restriction analysis of influenza-specific cloned cell lines issued from an HLA-DRw6/DR- donor. There was no pathologic evidence of canine distemper in that panda. Interplay of group and family treatment techniques in multifamily group therapy.

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The importance of the virulence of the strains used for the preparation of vaccines, as well as the method of their preparation, for the immunogenic potency of vaccines is shown. The metabolic significance of reduced serum B 12 in folate deficiency. Sleep-related oxygen desaturation and daytime pulmonary haemodynamics in COPD patients. To investigate the role of FasL in the apoptosis of lymphocytes in autoimmune diseases, gene and protein expression of FasL were examined in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA), and from healthy donors by a newly-designed semiquantitative reverse transcription (RT)-PCR and flow cytometry. Clinical course and outcome of primary acute angle-closure glaucoma in Singapore. The newly formed follicles can either incorporate into the existing gland, or form independent follicles. Comparison of total urinary coproporphyrin excretion in lead poisoning with other pathological conditions.

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