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Moduretic (Amiloride)
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Moduretic

Moduretic is a potassium-sparing diuretic (water pill) that helps your body to retain potassium, unlike other water pills. It doesn't have a huge effect on lowering your blood pressure, but it does help to restore potassium levels and prevent low potassium levels that can be caused by other water pills taken for high blood pressure or congestive heart failure.

Other names for this medication:
Acuren, Adelphan, Amiloride, Benazeplus, Bihasal, Clorana, Crinoretic, Disothiazide, Ditenside, Dociteren, Duradiuret, Emcoretic, Fosicombi, Fosicomp, Fosinopril, Fozide, Foziretic, Hidroclorotiazida, Hidrosaluretil, Hydrodiuril, Hydrozide, Hypodehydra, Hypothiazid, Iperton, Lisiplus, Monopril, Nefrix, Nephral, Prestole, Sectrazide, Timolide, Triamtereen, Triamteril, Zoprazide

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Also known as: Amiloride

Description

Moduretic is a diuretic (water pill) and a combination of a potassium-sparing diuretic (amiloride) and a thiazide diuretic (hydrochlorothiazide). It works by making the kidneys eliminate sodium (salt) and water from the body, which helps to lower blood pressure. The amiloride component helps minimize potassium loss. Brand name of Moduretic is Moduretic.

Dosage

Follow all directions on your prescription label. Do not take Moduretic 5-50 in larger or smaller amounts or for longer than recommended.

Take Moduretic 5-50 with food.

Your blood pressure will need to be checked often. Your blood and urine may also be tested if you have been vomiting or are dehydrated.

If you need surgery or medical tests, tell the doctor ahead of time that you are taking medication that contains hydrochlorothiazide. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture, heat, and light. Do not freeze.

Detailed Moduretic 5-50 dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Do not freeze. Keep container closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Moduretic are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Moduretic if you are allergic to Moduretic components or to any ingredient in Moduretic or any other sulfonamide (eg, sulfamethoxazole). Be careful with Moduretic if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Moduretic if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Moduretic if you have allergies to medicines, foods, or other substances. Be careful with Moduretic if you have cirrhosis or liver problems, diabetes, gout, kidney problems or kidney stones, asthma, heart problems, or systemic lupus erythematosus. Be careful with Moduretic if you have elevated blood acid, low folic acid levels, or electrolyte problems, or are dehydrated. Be careful with Moduretic if you take potassium-sparing diuretics (eg, spironolactone), potassium supplements, or salt substitutes containing potassium because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, or stopping of the heart; cholestyramine or colestipol because they may decrease Moduretic 's effectiveness; nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease Moduretic 's effectiveness and risk of kidney problems may be increased; barbiturates (eg, phenobarbital), certain chemotherapy medicines, corticosteroids (eg, prednisone), digoxin, dofetilide, ketanserin, narcotic pain medicines (eg, codeine), or medicines for high blood pressure because the risk of their side effects may be increased by Moduretic; diazoxide, lithium, or nondepolarizing neuromuscular blockers (eg, pancuronium) because their actions and the risk of their side effects may be increased by Moduretic; angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) because the risk of high blood potassium and kidney problems may be increased by Moduretic; diabetes medicines (eg, glipizide) or insulin because their effectiveness may be decreased by Moduretic. Do not stop taking Moduretic suddenly.

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Effects of endurance training on muscle fibre ATP-ase activity, capillary supply and mitochondrial content in man. At the single-cell level, three-color immunofluorescent studies revealed that both RSV-infected epithelial cells and alveolar macrophages expressed Class II molecules of the major histocompatibility complex, but only the alveolar macrophage coexpressed interleukin-1 beta. The Social Desirability Scale also was administered in order to assess the test-taking attitudes of the patients. This therapy resulted in the disappearance of transfusion requirements and in the increase of peripheral blood cell counts. Mineral phosphate (apatite) is activated for the synthesis of nucleotides when dilute solutions containing nucleoside and ammonium oxalate are evaporated in its presence. Three-dimensional imaging of trabecular bone using the computer numerically controlled milling technique.

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