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Nizoral (Ketoconazole)
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Nizoral

Nizoral is an antifungal shampoo. It slows the growth of the fungus causing your infection by stopping it from reproducing. Nizoral is a safe medication to use for dandruff and tinea versicolor.

Other names for this medication:
Apodruff, Clinhair, Danclear, Dancure, Danket, Emvate, Extina, Forfora, Funginoc, Hairdruff, Keticon, Ketoconazole, Ketodan, Ketosis, Ketovate, Ketozoe, Ketozole, Kezop, Ocona, Phytoral, Rivtar, Seldruff, Silkin, Velkin, Xolegel

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Astelin, Motrin, Danocrine, Neurontin, Aldara, Keflex, Cleocin, Omnicef, Compazine

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Also known as: Ketoconazole

Description

{name} (ketoconazole) is an antifungal medication that fights infections caused by fungus.

{name} is not for use in treating fungal infections of the fingernails or toenails. This medicine is also not for use in treating prostate cancer or Cushing syndrome.

{name} should be used only when you cannot use other antifungal medications. Ketoconazole can cause serious harm to your liver that may result in liver transplant or cause death.

Dosage

This section provides information on the proper use of a number of products that contain ketoconazole. It may not be specific to Nizoral A-D. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

For patients using the cream:

Apply enough cream to cover the affected and surrounding skin areas, and rub in gently. To help clear up your infection completely, it is very important that you keep using the cream for the full time of treatment, even if your symptoms begin to clear up after a few days. Since fungus or yeast infections may be very slow to clear up, you may have to continue using this medicine every day for up to several weeks. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses.

For patients using the foam:

Wash your hands before and after using this medicine. Do not spray the foam directly on your hand because it will begin to melt as soon as it touches your skin. Instead, spray the foam into the cap of the medicine can or other cool surface. Then dip your fingertips into the foam to pick up small amounts of the medicine, and apply to the affected skin areas. Gently massage the foam into your skin until it disappears. If you are treating skin areas with hair, such as your scalp, move any hair away so the foam can be applied directly to the affected skin. This medicine is flammable. Do not use it near heat, an open flame, or while smoking. Do not puncture, break, or burn the medicine can.

For patients using the gel:

Wash your hands before and after using this medicine. Apply enough ketoconazole gel to cover the affected and surrounding skin areas, and rub in gently with your fingertips. After applying this medicine, do not wash the affected area for at least 3 hours. Cosmetics (makeup or sunscreens) may be used on the treated skin areas no sooner than 20 minutes after this medicine is applied. This medicine may be flammable. Do not use it near heat, an open flame, or while smoking.

For patients using the 1% shampoo:

Wet your hair and scalp well with water. Apply enough shampoo to work up a good lather and gently massage it over your entire scalp. Rinse your hair and scalp with warm water. Repeat application. Rinse your hair and scalp well with warm water, and dry your hair.

For patients using the 2% shampoo:

Wet your hair and scalp well with water. Apply the shampoo to the skin of the affected area and a wide margin surrounding this area. Work up a good lather and leave it in place for 5 minutes. Rinse your hair and scalp well with warm water, and dry your hair.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For cream dosage form: For cutaneous candidiasis, tinea corporis, tinea cruris, tinea pedis, or pityriasis versicolor: Adults—Apply to the affected area of the skin and the surrounding area once a day. Children—Use and dose must be determined by your doctor. For seborrheic dermatitis: Adults—Apply to the affected area of the skin and the surrounding area two times per day. Children—Use and dose must be determined by your doctor. For foam dosage form: For seborrheic dermatitis: Adults—Apply to the affected area of the skin and the surrounding area two times per day for 4 weeks. Children—Use and dose must be determined by your doctor. For gel dosage form: For seborrheic dermatitis: Adults, teenagers, and children 12 years of age and older—Apply to the affected area of the skin and the surrounding area once a day for 2 weeks. Children younger than 12 years of age—Use and dose must be determined by your doctor. For 1% shampoo dosage form: For dandruff: Adults—Use every 3 or 4 days for up to 8 weeks. Then use only as needed to keep dandruff under control. Children—Use and dose must be determined by your doctor. For 2% shampoo dosage form: For pityriasis versicolor: Adults—Use once. Children—Use and dose must be determined by your doctor.

Overdose

An overdose of Nizoral A-D is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Nizoral are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Nizoral if you are allergic to Nizoral components. Do not take Nizoral if you are pregnant, planning to become pregnant, or are breast-feeding. Do not use Nizoral if you take astemizole (Hismanal), cisapride (Propulsid), midazolam (Versed), triazolam (Halcion). Be careful if you are taking oral diabetes medicine as glipizide (Glucotrol), chlorpropamide (Diabinese), glyburide (Glynase, Diabeta, Micronase), tolazamide (Tolinase), tolbutamide (Orinase); tacrolimus (Prograf); rifampin (Rimactane, Rifadin); warfarin (Coumadin); cyclosporine (Neoral, Sandimmune); antacids; famotidine (Pepcid, AC Pepcid), cimetidine (Tagamet HB, Tagamet), ranitidine (Zantac 75, Zantac), nizatidine (Axid AR, Axid); digoxin (Lanoxicaps, Lanoxin); methylprednisolone (Medrol); phenytoin (Dilantin); rabeprazole (Aciphex), omeprazole (Prilosec), lansoprazole (Prevacid). Be careful if you have liver disease, achlorhydria. Avoid consuming alcohol. Try to avoid machine driving. It can be dangerous to stop Nizoral taking suddenly.

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