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Nuvigil (Armodafinil)
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Nuvigil

Nuvigil is a medication that promotes wakefulness. Nuvigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. Nuvigil may also be used for purposes not listed in this medication guide.

Other names for this medication:
Armod, Armodafinil, Biryth, Waklert

Similar Products:
Seroquel, Motilium, Imitrex, Zyprexa, Colcrys, Pamelor, Soma

Also known as: Armodafinil

Description

Nuvigil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder).

This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Nuvigil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder.

It is not known how Nuvigil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.

Dosage

Take Nuvigil exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Armodafinil may be habit-forming. Never share Nuvigil with another person, especially someone with a history of drug abuse or addiction. Selling or giving away this medicine is against the law.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Nuvigil is usually taken each morning to prevent daytime sleepiness, or 1 hour before the start of a work shift to treat work-time sleep disorders.

You may take this medicine with or without food. Nuvigil is usually given for up to 12 weeks. Follow your doctor's instructions.

If you are taking this medicine to treat sleepiness caused by obstructive sleep apnea, you may also be treated with a continuous positive airway pressure (CPAP) machine. This machine is an air pump connected to mask that gently blows pressurized air into your nose while you sleep. The pump does not breathe for you, but the gentle force of air helps keep your airway open to prevent obstruction. Do not stop using your CPAP machine during sleep unless your doctor tells you to. The combination of treatment with CPAP and Nuvigil may be necessary to best treat your condition.

Taking this medication does not take the place of getting enough sleep. Talk with your doctor if you continue to have excessive sleepiness even while taking this medicine. Nuvigil will not cure obstructive sleep apnea or treat its underlying causes. Follow your doctor's instructions about all your other treatments for this disorder.

Overdose

If you take too much Nuvigil, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Storage

Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Nuvigil is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Nuvigil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Nuvigil if you are allergic to armodafinil or modafinil (Provigil).

To make sure Nuvigil is safe for you, tell your doctor if you have ever had:

liver or kidney disease; heart disease or a heart muscle or valve disorder such as mitral valve prolapse; high blood pressure, heart disease, or prior heart attack; mental illness or psychosis; or drug or alcohol addiction.

It is not known whether Nuvigil will harm an unborn baby. Nuvigil has been reported to be associated with growth restriction (small fetus) and miscarriage. Tell your doctor if you are pregnant or plan to become pregnant.

Use a barrier form of birth control (condom or diaphragm with spermicide). Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) will not effectively prevent pregnancy while you are taking Nuvigil.

It is not known whether Nuvigil passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Nuvigil is not approved for use by anyone younger than 17 years old.

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Frequency distribution of individuals aged 3-60 years according to gingival health status--a cross sectional study. Stimulus-induced accumulation of inositol tetrakis-, pentakis-, and hexakisphosphates in N1E-115 neuroblastoma cells. A comparison of these patterns shows that the mechanical activity of each region varies significantly during these phases of cardiac cycle. A labor and delivery service unit model for a multihospital health maintenance organization. Therefore, parenteral administration of nutrients may be advisable, pending the reversal of the exocrine and intestinal mucosal defect. Vascular occlusion may lead to impairment of the alveolar-capillary barrier and consequently an increase in the clearance of Tc-99m DTPA aerosol in embolized regions. This case is unusual in that there was the direct infusion of MTX into cerebral parenchyma, circumventing both the blood:brain and cerebrospinal fluid:brain barriers. To determine the influence of vitamin E on phylloquinone activity, one day-old chicks were raised on a masch diet supplemented with different amounts of vitamin E for 31 days. Resting metabolic rate increased by a bi- or triphasic pattern with body mass. In conclusion, our data indicate that the environment surrounding non-peptide antagonist and peptide agonists are vastly different when bound to the NK1 receptor.

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A rapid in vitro method for the evaluation of potential antitumor drugs requiring metabolic activation by hepatic S9 enzymes. It follows that tubocurarine does not act competitively with ACh at synapses when transmitter action is sufficiently brief, and that its binding to the receptor is probably diffusion-limited. Antibody titers of unknown sera were determined by comparison to known reference standard pool sera. Besides scoliosis, the usual roentgenograms, bone scans, CAT and MRI, did not show any relevant abnormality, which is a possibility that does not allow us to exclude the diagnosis of this tumor in a young patient with lower back pain and a rigid scoliosis. The sustained plasma glucose levels and decreased liver and muscle glycogen concentrations during cessation of feeding of the catfish suggest that during period of food deprivation, it draws its energy through glycogenolysis. A higher number of TUNEL-positive cells was found in the NT group, but they were significantly decreased in the HT group. The enhancements of release by the adrenergic antagonist yohimbine and by veratridine were not additive, suggesting a common site of action. The specificity of the test will dissect the chain of pathogenetic events from secondary consequences.(ABSTRACT TRUNCATED AT 250 WORDS). Influence of detergents on egg-white inhibition of hemagglutination by formolized swine influenza virus.

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Disproportionate shortening of DT with higher pressure-rate product during one-handed compared with two-handed weight-holding exercise can initiate an imbalance of myocardial oxygen supply and demand in patients with MI. A questionnaire survey was undertaken of individuals who either worked on the allotment or ate significant amounts of produce grown on it. These results indicate that the SFO mediates the effect of systemically administered ANG II on alcohol intake but does not otherwise affect the regulation of alcohol consumption. Oxidation activity of plant parts above the ground was quite low. In the case of an assumed hypertonic theory data can be explained only with the help of at least three ad hoc postulates. Lesions in the parietal operculum can i take diflucan while breastfeeding associated with persisting thalamic pain or loss of pain sensation have been reported, but rarely with episodic pain. As bulk concentration is increased, proportional tracer uptake diminishes and ultimately approaches zero. The Movement Assessment Battery for Children: a comparison of 4-year-old to 6-year-old children from Hong Kong and the United States. Stem cell behaviour, in particular the balance between self-renewal and differentiation, is ultimately controlled by the integration of intrinsic factors with extrinsic cues supplied by the surrounding microenvironment, known as the stem cell niche.

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Possible regulation of ornithine decarboxylase activity in the adrenal medulla of the rat by a cAMP-dependent mechanism. Two patients had a slightly elevated FTI and normal T4, and have remained clinically euthyroid. A consistent correlation was found between sensitivity to anchorage-dependent growth control and the presence of large, thick sheaths of actin-containing material. The indices did not correlate with the disease variants and gender but with age and PD complication. The purpose of this study was to test CFTR antibodies in paraffin-embedded skin biopsies to take advantage of the superior tissue preservation as compared to cryofixation. Cholinergic deafferentation exacerbates seizure-induced loss of somatostatin-immunoreactive neurons in the rat hippocampus. strain HO1-N grown on hydrocarbon and nonhydrocarbon substrates was compared using thin sections and freeze-etching. Fragments of DNA of the temperate phage P2, generated by treatment with the restriction enzyme PstI, have been cloned into the plasmid pBR322.

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