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Nuvigil (Armodafinil)

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Nuvigil is a medication that promotes wakefulness. Nuvigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. Nuvigil may also be used for purposes not listed in this medication guide.

Other names for this medication:
Armod, Armodafinil, Biryth, Waklert

Similar Products:
Seroquel, Motilium, Imitrex, Zyprexa, Colcrys, Pamelor, Soma

Also known as: Armodafinil


Nuvigil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder).

This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Nuvigil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder.

It is not known how Nuvigil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.


Take Nuvigil exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Armodafinil may be habit-forming. Never share Nuvigil with another person, especially someone with a history of drug abuse or addiction. Selling or giving away this medicine is against the law.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Nuvigil is usually taken each morning to prevent daytime sleepiness, or 1 hour before the start of a work shift to treat work-time sleep disorders.

You may take this medicine with or without food. Nuvigil is usually given for up to 12 weeks. Follow your doctor's instructions.

If you are taking this medicine to treat sleepiness caused by obstructive sleep apnea, you may also be treated with a continuous positive airway pressure (CPAP) machine. This machine is an air pump connected to mask that gently blows pressurized air into your nose while you sleep. The pump does not breathe for you, but the gentle force of air helps keep your airway open to prevent obstruction. Do not stop using your CPAP machine during sleep unless your doctor tells you to. The combination of treatment with CPAP and Nuvigil may be necessary to best treat your condition.

Taking this medication does not take the place of getting enough sleep. Talk with your doctor if you continue to have excessive sleepiness even while taking this medicine. Nuvigil will not cure obstructive sleep apnea or treat its underlying causes. Follow your doctor's instructions about all your other treatments for this disorder.


If you take too much Nuvigil, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.


Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Nuvigil is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Nuvigil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Nuvigil if you are allergic to armodafinil or modafinil (Provigil).

To make sure Nuvigil is safe for you, tell your doctor if you have ever had:

liver or kidney disease; heart disease or a heart muscle or valve disorder such as mitral valve prolapse; high blood pressure, heart disease, or prior heart attack; mental illness or psychosis; or drug or alcohol addiction.

It is not known whether Nuvigil will harm an unborn baby. Nuvigil has been reported to be associated with growth restriction (small fetus) and miscarriage. Tell your doctor if you are pregnant or plan to become pregnant.

Use a barrier form of birth control (condom or diaphragm with spermicide). Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) will not effectively prevent pregnancy while you are taking Nuvigil.

It is not known whether Nuvigil passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Nuvigil is not approved for use by anyone younger than 17 years old.

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