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From these findings, it is indicated that 1) 5-HT reuptake inhibitors decrease anxiety, 2) 5-HT release is increased at the nerve terminal under anxiety conditions, 3) the elevation of 5-HT levels in the terminal has an anxiolytic action which is closely related to the pharmacological effects of SSRI-class of anxiolytics, and 4) 5-HT1A receptor antagonist enhances the antifreezing effect of SSRI by blocking the autoreceptor-mediated negative feedback mechanisms of 5-HT neurons. Virus markers useful in the determination of the etiology of virus-free tumors are described, including viral DNA, viral mRNA, virus-induced antigens, and the rescue of infectious virus. Conservative treatment of occult gallbladder perforation is possible and should be performed in high-risk patients. After a mean follow-up period of 40.5 months, all patients except 2 revealed normal physical findings and renal function as well as urinary findings. The lens was surgically removed from one eye of 3 macaques during the first month of life. In the past year, much has been learned about structure-function correlations in the tubulin molecule, and specifically about the nature and roles of post-translational modifications and tubulin isotypes. Letter: The isolation of a herpesvirus from pigeon and experimental infection in psittacine birds. Recommendations on the interpretation and evaluation of juvenile electrocardiograms. All 24 schools in North Karelia province and 16 randomly selected schools in Kuopio province. The results do not support the suggestion that inhibition of the exocytotic release of transmitter is responsible for the early in vitro effects of these drugs.
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It is clear that the major proportion of bone and dentin NCM consists of glycoproteins of the less-acidic and anionic types. In this study we use an in vivo UV crosslinking procedure to probe the interactions of TLS with RNA. Estrone, estradiol, and testosterone were not injurious in this regard at the dosages used. 125I-iodo IGF 2 was degraded more rapidly than was 125I-iodo IGF 1. The genetic variation and epidemiology of HIV-1 group O isolates are of considerable importance to the design of HIV-1 diagnostic and screening assays, especially since current serologic and genetic methods to detect HIV-1 have been developed mainly on the basis of sequences from isolates belonging to HIV-1 group M. We report a patient with symptomatic AV block associated with conduction solely through an atriofascicular pathway that inserted into the left bundle branch. In both models, hyperthermia significantly reduced pancreatic injury. Autocrine nitric oxide modulates CD95-induced apoptosis in gammadelta T lymphocytes.
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The excitatory input to SNPR could contribute to the damage observed. 4 women with cervical and endometrial cancer (stages I and II) and treated with the same doses of physiological saline solution were used as controls. The system could be operated in two modes: beta optimized, in which the difference between the signals from the two detectors was calculated to correct the beta signal for photon contamination, and photon-optimized mode, in which the signals were summed. Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients. Adrenal reserve in diabetes insipidus treated with chlorpropamide. cerebral cortex, corpus striatum, medulla, cerebellum and hypothalamus. Diabetes was found to inhibit all three parameters of fertility.
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Regulation of protein kinase B in rat adipocytes by insulin, vanadate, and peroxovanadate. There was no statistically significant difference in tumor responses and in recurrence--free survival time between the patients who received irradiation and misonidazole as compared to those who received irradiation and placebos. Tissue bound autoantibodies in genital organs of infertile couples. The desiccant was unable to remove all the water from the samples, which indicated that some water was tightly held within the sample matrix. On the molecular structure of the nucleosome core particle of chromatin.
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Continuous registration of physiological functions of the organism during stimulation of the vestibular analysor with the aid of an electrically vibrated chair. Clastogenic and physiological response of chromosomes to nine pesticides in the Vicia faba in vivo root tip assay system. Intrapericardial treatment with 300 mg/m2 triamcinolone was for the first time performed in patients with autoreactive myopericarditis and minimal pericardial effusions (75 to 110 ml). Six patients between 61 to 84 years of age died in the early postoperative period during their stay in hospital. Increasing the concentration of antigen in the CFT reduced the tendency to prozone. Thus, at least with respect to the number of responses emitted, a sex dependency of visual lateralization could not be demonstrated. One of the sites of linkage between the left terminus of Ad12 DNA and mouse DNA was cloned, mapped and sequenced by using conventional techniques. Increased expression of clusterin has been identified in several cases of tissues undergoing apoptosis (programmed cell death), and our finding suggests that the degenerative changes in advanced RP may represent another example of apoptosis, possibly with common causative mechanisms. Each of several current models can explain some of our results, but no one of them seems capable of accounting for all three sets of data.
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A technique for experimental determination of regional myocardial blood flow and heat generation has been developed, based on a heat-clearance method. Although G-CSF stimulated the proliferation of leukemic progenitor cells to form leukemic blast colonies, the chimeric soluble G-CSF receptor completely inhibited this stimulatory effect. Contribution to the prevalence of cholecystolithiasis in patients with familial hyperlipoproteinaemia. Eight different known molecular defects were detected, at different frequencies. This technique is the basis for recently initiated clinical studies. Comparison of ciprofloxacin hydrochloride-loaded protein, lipid, and chitosan nanoparticles for drug delivery. This research tested the hypothesis that behavioral standards in a drinking situation are learned. Experimental selenium toxicity in guinea pigs: haematological studies. Overall, tobramycin seemed the most effective of the drugs studied. These data suggest that bradykinin enhanced the nutritional flow across the capillary wall and, thereby, indirectly accelerates the glucose metabolism in the isolated perfused heart.
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Laser in situ keratomileusis for myopia of -1 to -3.50 diopters. We show that similar pairwise homogenizations occur in the chimpanzee (Pan troglodytes), where chromosomes 14 and 22, homologous to human chromosomes 13 and 21, share one partially homogenized alphoid DNA subfamily and chromosomes 15 and 23, homologous to human chromosomes 14 and 22, share another extensively homogenized subfamily. Terminal-deoxynucleotidyl transferase (TdT): serial observations on patients with leukemia. Effect of expression of exogenous PDGF-A chain on growth and transformation of CHO cells. Interrelationship between disease activity and nutrient intake or serum cytokine in patients with rheumatoid arthritis. No essential differences in G6PD levels were seen in animals inoculated with physiological saline when compared with uninoculated controls. Addition of tetracycline nearly completely repressed activator-dependent transcription from the tetO-HOP1 promoter.
Intracellular injection of the gap junction permeable fluorescent dye Lucifer Yellow and ionic current were used to establish the presence of coupling among these identified cells. Renal kallikrein and PGE in the exaggerated fractional Na excretion in patients with chronic renal failure. The method can also be applied as an electro-concentration system in a field-strength gradient. We believe that the use of propofol and alfentanil as an induction and maintenance regimen for military anaesthesia merits further evaluation and comparison with established techniques. To examine the effect of once-daily dosing of modafinil, a stimulant that has a long duration of action, on clinical features of attention-deficit/hyperactivity disorder (ADHD) in children.