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Sildenafila

Sildenafila is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. Its effectiveness for treating sexual dysfunction in women has not been demonstrated. Pfizer scientists Andrew Bell, David Brown, and Nicholas Terrett originally discovered sildenafil as a treatment for various cardiovascular disorders. Since becoming available in 1998, sildenafil has been a common treatment for erectile dysfunction The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus.

Other names for this medication:
Caverta, Intagra, Kamagra, Penegra, Revatio, Silagra, Sildenafil, Sildenafila, Sildenafilo, Sildenafilum, Sildigra, Suhagra, Veega, Zenegra

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Also known as: Sildenafil

Description

Viagra is the brand name for sildenafil citrate and is used to treat erectile dysfunction and pulmonary arterial hypertension.

Originally developed by scientists in the United Kingdom, it was brought onto the market by Pfizer Inc., an American pharmaceutical company.

Viagra can help men who cannot achieve or sustain an erection due to erectile dysfunction. It improves the erectile response when a man is already sexually stimulated, but it does not provide sexual stimulation. If there is no sexual stimulation, viagra will not work.

When sexual stimulation occurs, nitric oxide is released by the nervous system in the erectile tissue of the penis. Nitric oxide stimulates an enzyme that produces messenger cyclic guanosine monophosphate (cGMP).

cGMP causes the arteries in the penis to dilate, so that the arteries and the erectile tissue fill with blood. An erection results.

Viagra prevents cGMP from becoming degraded, so the blood flow and the erection can continue.

Dosage

The Sildenafila dosage your doctor prescribes will depend on several factors. These include:

  • your age
  • whether you have liver or kidney problems
  • other medical conditions you may have
  • other medications you may be taking
The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug forms and strengths

Sildenafila comes as tablets that are taken by mouth. It’s available in three strengths: 25 mg, 50 mg, and 100 mg.

Dosage for ED

The typical dose of Sildenafila for erectile dysfunction (ED) is 50 mg. You can take this dose 30 minutes to 4 hours before you plan to have sexual activity. But for most people, it’s recommended that you take your dose about an hour before having sex. Don’t take Sildenafila more than once a day.

Your doctor may prescribe a different dosage of Sildenafila for you depending on several factors. These factors may include whether you have liver or kidney problems, or if you’re taking certain other medications. If any of these factors apply to you, your starting dose might be 25 mg, which is lower than the typical recommended dose.

If you have questions about the Sildenafila dosage that’s right for you, talk with your doctor.

And keep in mind that if Sildenafila isn’t working for you, your doctor may increase your dose of the drug. But the maximum dose of Sildenafila is 100 mg.

Dosage questions

Below, we answer some common questions related to Sildenafila’s dosage.

Is Sildenafila’s dosage based on age or weight?

Your dosage of Sildenafila won’t be based on your weight, but it may be based on your age.

For example, people ages 65 years and older tend to get higher levels of Sildenafila in their blood after taking a dose. So, if you’re over 65 years of age, your doctor will usually recommend a starting dose of Sildenafila for you that’s lower than the typical starting dose. For example, they may recommend that you take 25 mg of the drug rather than 50 mg.

Can I take Sildenafila just for fun, even if I don’t have ED? If so, how much is safe to take?

No, you shouldn’t take Sildenafila if you don’t have ED. Sildenafila is a prescription medication that can have serious side effects. And it’s approved only to treat ED, not to be used recreationally.

You should only take Sildenafila if it’s been prescribed to you by a doctor who knows your medical history.

Will I need to use this drug long term?

Maybe. If you and your doctor determine that Sildenafila is safe and effective for you, you can likely take it for as long as you continue to need it.

Overdose

If you take an overdose of Sildenafila, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store Viagra at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Viagra out of the reach of children and away from pets.

Side effects

The most common side effects associated with Sildenafila are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Sildenafila if you are allergic to sildenafil, or:

if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas). if you take nitrates.

Do not take Sildenafila if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

To make sure Sildenafila is safe for you, tell your doctor if you have ever had:

heart disease or heart rhythm problems, coronary artery disease; a heart attack, stroke, or congestive heart failure; high or low blood pressure; liver or kidney disease; a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a bleeding disorder such as hemophilia; a stomach ulcer; retinitis pigmentosa (an inherited condition of the eye); a physical deformity of the penis (such as Peyronie's disease); or if you have been told you should not have sexual intercourse for health reasons.

Sildenafila can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether sildenafil is the actual cause of vision loss.

Sildenafila is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether sildenafil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medicine to anyone under 18 years old without medical advice.

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A total of 334 Korean cancer patients participated in this cross-sectional study. Development of optimized combination and clinical application of thrombosis and hemostasis experimental study. Paramyxovirus matrix (M) proteins organize virus assembly, functioning as adapters that link together viral ribonucleoprotein complexes and viral glycoproteins at infected cell plasma membranes. Patients with post-traumatic stress disorder (PTSD) exhibit exaggerated daytime muscle tension as well as nocturnal sleep disturbances. Leukotrienes: potential therapeutic targets in cardiovascular diseases. Between May and December 2005, 64 multidrug-resistant isolates of Klebsiella pneumoniae were detected from patients admitted to Uppsala University Hospital. A 61-year-old man presented with 20/200 vision in the right eye because of a branch retinal vein occlusion secondary to a RAM. Our results show that increased cardiac and vascular complications along with short survival in nephrogenic systemic fibrosis are associated with metal accumulation in the heart, blood vessels, and skin of these patients. Of desk-economists and doctors at the bedside within a health care system: they should learn from each other.

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To study the clinical and genetic characteristics of generalized epilepsy with febrile seizures plus (GEFS). Notalgia paresthetica is a chronic sensory neuropathy characterized by pruritus of the upper to middle back, typically below the left shoulder blade. Lexical decision task in an event-related potential experiment was used in order to determine the organization of mental lexicon regarding the polimorphemic words: are they stored as unanalyzable items or as separate morphemes?. Recurrences are infrequent, and distant metastasis has never been reported. Also, the lumican LRR 7 sequence-based synthetic peptide CYLDNNKC inhibits the binding to collagen. The ongoing research about it in Department of Cleft Lip and Palate Surgery in West China College of Stomatology of Sichuan University is one of the earliest domestically researches, so there must be some learnable experiences from it. Twenty-two studies were found, which showed a large variety in research designs, instruments and populations. A tree based on the nuclear ornithine decarboxylase (ODC) introns 6-7 is unresolved with respect to the ingroup, but provides strong support for a clade containing the Lanius excubitor complex, L. Elemental mapping demonstrates that the relative abundance of elements varies between different anatomical features of the specimens. The aim of this cadaveric study was to assess and compare the distance of commonly used dorsal wrist portals to the dorsal ulnar and radial superficial nerves and their branches.

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Anesthetic considerations in patients with cardiomyopathies --a review. Both serotonin- and angiotensin II-dependent cytokine production occur via a Src/heparin-binding epidermal growth factor-dependent transactivation of epidermal growth factor receptors in cardiac fibroblasts, supporting a common signaling pathway. Research suggests that individuals with social phobia fear positive social events and interpret them in a negative fashion that serves to maintain anxiety. Correlation analysis, principal components analysis and stepwise least squares multiple regression were used to determine the spatio-temporal variability of water quality variables and in particular their correlations with land use/land cover in the 100 m riparian zone along the stream network. Access to new anatomical work on the living platypus, Ornithorhynchus anatinus, and the present comparative study of the cranial foramina of Ob. Can We Bring about a Velvet Revolution in Psychological Measurement?.

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Surfactant protein A2 gene expression by human airway submucosal gland cells. Both antisera were found to inhibit, when microinjected into Drosophila ovarian follicles, the intercellular exchange of fluorescent tracer molecules between oocyte and follicle epithelium. Are release recommendations for NGRI acquittees informed by relevant data?. Median age of patients was 54 (28-69), 16/17 were female, ECOG performance status was 0/1 in 16 patients. The RRAM characteristics are critically influenced by the thickness of the Al(2) O(3) barrier layer, which prevents significant migration of Ag into the CdS layer as revealed by Auger electron spectroscopy (AES). To help in the assignments, some of these compounds were studied in DMSO-d(6) solution. in the first trimester also significantly increased the risk of second trimester pregnancy loss. Here we discuss the structural basis of non-consensus SH3 ligand binding and the dominant role of the SH3 domain specificity zone in selective target recognition, and review some of the best-characterized examples of such interactions. After total resection of the tumor, histopathological diagnosis revealed a gangliocytic paraganglioma.

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The reorganization of microtubules induced by salt stress is required for Arabidopsis survival under high salinity conditions. However, measurement of trefoil with this instrument is less repeatable. The combination of laser-induced acoustic desorption and electrospray ionization mass spectrometry (LIAD/ESI/MS) can be used to rapidly characterize chemical compounds separated on a thin layer chromatography (TLC) plate. Even if abortion jurisprudence is deemed to apply in the partial-birth context, a federal style ban is still constitutional under Casey because a ban on partial-birth abortions does not impose an undue burden on abortion rights. Additionally vasotec generic brand , it is expected that the diesel biofuel norms will be extended to ethyl esters produced from bioethanol in the upcoming years.

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To develop a clinical tool that predicts pregnancy rates (PRs) in patients with surgically documented endometriosis who attempt non-IVF conception. Few articles have reported on it and those that have enrolled few patients. M-line titin homozygous truncations cause the first congenital and purely recessive titinopathy, and the first to involve both cardiac and skeletal muscle. This prospective study confirms the complications rate of ERCP including therapeutic procedures is low in our experience. These findings indicate that nucleus reuniens represents a critical link between the medial prefrontal cortex and the hippocampus.

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